메뉴 건너뛰기




Volumn 2, Issue 4, 2012, Pages 272-283

Polycaprolactone scaffold as targeted drug delivery system and cell attachment scaffold for postsurgical care of limb salvage

Author keywords

Polycaprolactone; Scaffold; Targeted drug delivery; Tissue engineering

Indexed keywords

DOXORUBICIN; LIDOCAINE; MACROGOL DERIVATIVE; POLY(ETHYLENE GLYCOL) DIACRYLATE; POLYCAPROLACTONE; RHODAMINE B; TISSUE SCAFFOLD; UNCLASSIFIED DRUG;

EID: 84866147356     PISSN: 2190393X     EISSN: 21903948     Source Type: Journal    
DOI: 10.1007/s13346-012-0096-9     Document Type: Article
Times cited : (34)

References (50)
  • 1
    • 0027903339 scopus 로고
    • Limb salvage tumor surgery in children
    • Lindell EB, Carroll NC. Limb salvage tumor surgery in children. Iowa Orthop J. 1993; 13: 124-35.
    • (1993) Iowa Orthop J , vol.13 , pp. 124-135
    • Lindell, E.B.1    Carroll, N.C.2
  • 3
    • 69049092640 scopus 로고    scopus 로고
    • Impairment and disability following limb salvage procedures for bone sarcoma
    • doi:10.1016/j.knee.2009.02.006
    • Carty CP, Dickinson IC, Watts MC, Crawford RW, Steadman P. Impairment and disability following limb salvage procedures for bone sarcoma. Knee. 2009; 16(5): 405-8.
    • (2009) Knee , vol.16 , Issue.5 , pp. 405-408
    • Carty, C.P.1    Dickinson, I.C.2    Watts, M.C.3    Crawford, R.W.4    Steadman, P.5
  • 4
    • 0023890926 scopus 로고
    • Metallic wear in failed titanium-alloy total hip replacements. A histological and quantitative analysis
    • Agins HJ, Alcock NW, Bansal M, Salvati EA, Wilson Jr PD, Pellicci PM, et al. Metallic wear in failed titanium-alloy total hip replacements. A histological and quantitative analysis. J Bone Joint Surg Am. 1988; 70(3): 347-56.
    • (1988) J Bone Joint Surg Am , vol.70 , Issue.3 , pp. 347-356
    • Agins, H.J.1    Alcock, N.W.2    Bansal, M.3    Salvati, E.A.4    Wilson Jr., P.D.5    Pellicci, P.M.6
  • 6
    • 0020670519 scopus 로고
    • The effects of metal plates on post-traumatic remodelling and bone mass
    • Uhthoff HK, Finnegan M. The effects of metal plates on post-traumatic remodelling and bone mass. J Bone Joint Surg Br. 1983; 65(1): 66-71.
    • (1983) J Bone Joint Surg Br , vol.65 , Issue.1 , pp. 66-71
    • Uhthoff, H.K.1    Finnegan, M.2
  • 7
    • 0028157344 scopus 로고
    • The effects of rigid fixation on craniofacial growth of rhesus monkeys
    • discussion 1-5
    • Yaremchuk MJ, Fiala TG, Barker F, Ragland R. The effects of rigid fixation on craniofacial growth of rhesus monkeys. Plast Reconstr Surg. 1994; 93(1): 1-10. discussion 1-5.
    • (1994) Plast Reconstr Surg , vol.93 , Issue.1 , pp. 1-10
    • Yaremchuk, M.J.1    Fiala, T.G.2    Barker, F.3    Ragland, R.4
  • 8
    • 0027998049 scopus 로고
    • Cranio-orbital reconstruction: safety and image quality of metallic implants on CT and MRI scanning
    • Sullivan PK, Smith JF, Rozzelle AA. Cranio-orbital reconstruction: safety and image quality of metallic implants on CT and MRI scanning. Plast Reconstr Surg. 1994; 94(5): 589-96.
    • (1994) Plast Reconstr Surg , vol.94 , Issue.5 , pp. 589-596
    • Sullivan, P.K.1    Smith, J.F.2    Rozzelle, A.A.3
  • 9
    • 47849123487 scopus 로고    scopus 로고
    • Preliminary experience with biodegradable implants for fracture fixation
    • doi:10.4103/0019-5413.41856
    • Dhillon MS, Prabhakar S, Prasanna C. Preliminary experience with biodegradable implants for fracture fixation. Indian J Orthop. 2008; 42(3): 319-22.
    • (2008) Indian J Orthop , vol.42 , Issue.3 , pp. 319-322
    • Dhillon, M.S.1    Prabhakar, S.2    Prasanna, C.3
  • 11
    • 0035380036 scopus 로고    scopus 로고
    • Synthetic bone graft substitutes
    • doi:10.1046/j.1440-1622.2001.02128.x
    • Moore WR, Graves SE, Bain GI. Synthetic bone graft substitutes. ANZ J Surg. 2001; 71(6): 354-61.
    • (2001) ANZ J Surg , vol.71 , Issue.6 , pp. 354-361
    • Moore, W.R.1    Graves, S.E.2    Bain, G.I.3
  • 12
    • 0024832051 scopus 로고
    • Harvesting autogenous iliac bone grafts. A review of complications and techniques
    • Kurz LT, Garfin SR, Booth Jr RE. Harvesting autogenous iliac bone grafts. A review of complications and techniques. Spine (Phila Pa 1976). 1989; 14(12): 1324-31.
    • (1989) Spine (Phila Pa 1976) , vol.14 , Issue.12 , pp. 1324-1331
    • Kurz, L.T.1    Garfin, S.R.2    Booth Jr., R.E.3
  • 13
    • 33644612205 scopus 로고    scopus 로고
    • Cranioplasty after trephination using a novel biodegradable burr hole cover: technical case report
    • discussion ONS-E176, ONS-E176
    • Schantz JT, Lim TC, Ning C, Teoh SH, Tan KC, Wang SC, et al. Cranioplasty after trephination using a novel biodegradable burr hole cover: technical case report. Neurosurgery. 2006; 58(1 Suppl): ONS-E176. discussion ONS-E176.
    • (2006) Neurosurgery , vol.58 , Issue.1 SUPPL.
    • Schantz, J.T.1    Lim, T.C.2    Ning, C.3    Teoh, S.H.4    Tan, K.C.5    Wang, S.C.6
  • 14
    • 64549145109 scopus 로고    scopus 로고
    • Mandibular defect reconstruction using three-dimensional polycaprolactone scaffold in combination with platelet-rich plasma and recombinant human bone morphogenetic protein-2: de novo synthesis of bone in a single case
    • Schuckert KH, Jopp S, Teoh SH. Mandibular defect reconstruction using three-dimensional polycaprolactone scaffold in combination with platelet-rich plasma and recombinant human bone morphogenetic protein-2: de novo synthesis of bone in a single case. Tissue Eng Part A. 2009; 15(3): 493-9.
    • (2009) Tissue Eng Part A , vol.15 , Issue.3 , pp. 493-499
    • Schuckert, K.H.1    Jopp, S.2    Teoh, S.H.3
  • 15
    • 0020059356 scopus 로고
    • Preoperative chemotherapy for osteogenic-sarcoma: selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy
    • Rosen G, Caparros B, Huvos AG, Kosloff C, Nirenberg A, Cacavio A, et al. Preoperative chemotherapy for osteogenic-sarcoma: selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy. Cancer. 1982; 49(6): 1221-30.
    • (1982) Cancer , vol.49 , Issue.6 , pp. 1221-1230
    • Rosen, G.1    Caparros, B.2    Huvos, A.G.3    Kosloff, C.4    Nirenberg, A.5    Cacavio, A.6
  • 16
    • 71949105972 scopus 로고    scopus 로고
    • Doxorubicin loaded polymeric nanoparticulate delivery system to overcome drug resistance in osteosarcoma
    • Susa M, Iyer AK, Ryu K, Hornicek FJ, Mankin H, Amiji MM, et al. Doxorubicin loaded polymeric nanoparticulate delivery system to overcome drug resistance in osteosarcoma. BMC Cancer. 2009; 9: 399.
    • (2009) BMC Cancer , vol.9 , pp. 399
    • Susa, M.1    Iyer, A.K.2    Ryu, K.3    Hornicek, F.J.4    Mankin, H.5    Amiji, M.M.6
  • 17
    • 77954333247 scopus 로고    scopus 로고
    • Bone sarcomas: ESMO clinical practice guidelines for diagnosis, treatment and follow-up
    • Hogendoorn PC, Athanasou N, Bielack S, De Alava E, Dei Tos AP, Ferrari S, et al. Bone sarcomas: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2010; 21 Suppl 5: v204-13.
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. 5
    • Hogendoorn, P.C.1    Athanasou, N.2    Bielack, S.3    de Alava, E.4    Dei Tos, A.P.5    Ferrari, S.6
  • 18
    • 79959837515 scopus 로고    scopus 로고
    • A novel hyperthermia treatment for bone metastases using magnetic materials
    • doi:10.1007/s10147-011-0217-3
    • Matsumine A, Takegami K, Asanuma K, Matsubara T, Nakamura T, Uchida A, et al. A novel hyperthermia treatment for bone metastases using magnetic materials. Int J Clin Oncol. 2011; 16(2): 101-8.
    • (2011) Int J Clin Oncol , vol.16 , Issue.2 , pp. 101-108
    • Matsumine, A.1    Takegami, K.2    Asanuma, K.3    Matsubara, T.4    Nakamura, T.5    Uchida, A.6
  • 19
    • 22544460778 scopus 로고    scopus 로고
    • Infections in children and young adults with bone malignancies undergoing limb-sparing surgery
    • Gaur AH, Liu T, Knapp KM, Daw NC, Rao BN, Neel MD, et al. Infections in children and young adults with bone malignancies undergoing limb-sparing surgery. Cancer. 2005; 104(3): 602-10.
    • (2005) Cancer , vol.104 , Issue.3 , pp. 602-610
    • Gaur, A.H.1    Liu, T.2    Knapp, K.M.3    Daw, N.C.4    Rao, B.N.5    Neel, M.D.6
  • 20
    • 79951904017 scopus 로고    scopus 로고
    • Painful sequelae following limb salvage: etiology and management
    • Goff BJ, Castillo R, Raja SN. Painful sequelae following limb salvage: etiology and management. J Am Acad Orthop Surg. 2011; 19 Suppl 1: S23-7.
    • (2011) J Am Acad Orthop Surg , vol.19 , Issue.SUPPL. 1
    • Goff, B.J.1    Castillo, R.2    Raja, S.N.3
  • 21
    • 70450221930 scopus 로고    scopus 로고
    • Biodegradable polymeric nanoparticles based drug delivery systems
    • Kumari A, Yadav SK, Yadav SC. Biodegradable polymeric nanoparticles based drug delivery systems. Colloids Surf B Biointerfaces. 2010; 75(1): 1-18.
    • (2010) Colloids Surf B Biointerfaces , vol.75 , Issue.1 , pp. 1-18
    • Kumari, A.1    Yadav, S.K.2    Yadav, S.C.3
  • 22
    • 70349480763 scopus 로고    scopus 로고
    • Poly(epsilon-caprolactone)/poly(ethylene glycol)/poly(epsilon-caprolactone) nanoparticles: preparation, characterization, and application in doxorubicin delivery
    • Gou M, Zheng X, Men K, Zhang J, Zheng L, Wang X, et al. Poly(epsilon-caprolactone)/poly(ethylene glycol)/poly(epsilon-caprolactone) nanoparticles: preparation, characterization, and application in doxorubicin delivery. J Phys Chem B. 2009; 113(39): 12928-33.
    • (2009) J Phys Chem B , vol.113 , Issue.39 , pp. 12928-12933
    • Gou, M.1    Zheng, X.2    Men, K.3    Zhang, J.4    Zheng, L.5    Wang, X.6
  • 23
    • 55049137346 scopus 로고    scopus 로고
    • Superior antitumor efficiency of cisplatin-loaded nanoparticles by intratumoral delivery with decreased tumor metabolism rate
    • Li X, Li R, Qian X, Ding Y, Tu Y, Guo R, et al. Superior antitumor efficiency of cisplatin-loaded nanoparticles by intratumoral delivery with decreased tumor metabolism rate. Eur J Pharm Biopharm. 2008; 70(3): 726-34.
    • (2008) Eur J Pharm Biopharm , vol.70 , Issue.3 , pp. 726-734
    • Li, X.1    Li, R.2    Qian, X.3    Ding, Y.4    Tu, Y.5    Guo, R.6
  • 24
    • 78349308872 scopus 로고    scopus 로고
    • Polycaprolactone-based fused deposition modeled mesh for delivery of antibacterial agents to infected wounds
    • Teo EY, Ong SY, Chong MS, Zhang Z, Lu J, Moochhala S, et al. Polycaprolactone-based fused deposition modeled mesh for delivery of antibacterial agents to infected wounds. Biomaterials. 2011; 32(1): 279-87.
    • (2011) Biomaterials , vol.32 , Issue.1 , pp. 279-287
    • Teo, E.Y.1    Ong, S.Y.2    Chong, M.S.3    Zhang, Z.4    Lu, J.5    Moochhala, S.6
  • 25
    • 70649085278 scopus 로고    scopus 로고
    • Microfabrication-derived DDS: from batch to individual production
    • Takada K. Microfabrication-derived DDS: from batch to individual production. Drug Discov Ther. 2008; 2(3): 140-55.
    • (2008) Drug Discov Ther , vol.2 , Issue.3 , pp. 140-155
    • Takada, K.1
  • 26
    • 0033102401 scopus 로고    scopus 로고
    • A novel fabrication of poly(ε-caprolactone) microspheres from blends of poly(ε-caprolactone) and poly(ethylene glycol)s
    • Lin W-J, Flanagan DR, Linhardt RJ. A novel fabrication of poly(ε-caprolactone) microspheres from blends of poly(ε-caprolactone) and poly(ethylene glycol)s. Polymer. 1999; 40(7): 1731-5.
    • (1999) Polymer , vol.40 , Issue.7 , pp. 1731-1735
    • Lin, W.-J.1    Flanagan, D.R.2    Linhardt, R.J.3
  • 28
    • 59749092851 scopus 로고    scopus 로고
    • 3D polycarprolactone (PCL) scaffold with hierarchical structure fabricated by a piezoelectric transducer (PZT)-assisted bioplotter
    • Kim GH, Son JG. 3D polycarprolactone (PCL) scaffold with hierarchical structure fabricated by a piezoelectric transducer (PZT)-assisted bioplotter. Appl Phys A Mater. 2009; 94(4): 781-5.
    • (2009) Appl Phys A Mater , vol.94 , Issue.4 , pp. 781-785
    • Kim, G.H.1    Son, J.G.2
  • 29
    • 79956196821 scopus 로고    scopus 로고
    • Fabrication of porous polycaprolactone/hydroxyapatite (PCL/HA) blend scaffolds using a 3D plotting system for bone tissue engineering
    • Park SA, Lee SH, Kim WD. Fabrication of porous polycaprolactone/hydroxyapatite (PCL/HA) blend scaffolds using a 3D plotting system for bone tissue engineering. Bioprocess Biosyst Eng. 2011; 34(4): 505-13.
    • (2011) Bioprocess Biosyst Eng , vol.34 , Issue.4 , pp. 505-513
    • Park, S.A.1    Lee, S.H.2    Kim, W.D.3
  • 30
    • 67449126802 scopus 로고    scopus 로고
    • From natural bone grafts to tissue engineering therapeutics: brainstorming on pharmaceutical formulative requirements and challenges
    • Baroli B. From natural bone grafts to tissue engineering therapeutics: brainstorming on pharmaceutical formulative requirements and challenges. J Pharm Sci. 2009; 98(4): 1317-75.
    • (2009) J Pharm Sci , vol.98 , Issue.4 , pp. 1317-1375
    • Baroli, B.1
  • 31
    • 74049143921 scopus 로고    scopus 로고
    • Bone tissue engineering therapeutics: controlled drug delivery in three-dimensional scaffolds
    • Mouriño V, Boccaccini AR. Bone tissue engineering therapeutics: controlled drug delivery in three-dimensional scaffolds. J R Soc Interface. 2010; 7(43): 209-27.
    • (2010) J R Soc Interface , vol.7 , Issue.43 , pp. 209-227
    • Mouriño, V.1    Boccaccini, A.R.2
  • 32
    • 84866179599 scopus 로고    scopus 로고
    • A simple method of microneedle array fabrication for transdermal drug delivery
    • In press
    • Kochhar JS, Goh WJ, Chan SY, Kang L. A simple method of microneedle array fabrication for transdermal drug delivery. Drug Dev Ind Pharm. 2012; in press.
    • (2012) Drug Dev Ind Pharm
    • Kochhar, J.S.1    Goh, W.J.2    Chan, S.Y.3    Kang, L.4
  • 33
    • 77956185544 scopus 로고    scopus 로고
    • A novel two-level microstructured poly(N-isopropylacrylamide) hydrogel for controlled release
    • Zhang JT, Keller TF, Bhat R, Garipcan B, Jandt KD. A novel two-level microstructured poly(N-isopropylacrylamide) hydrogel for controlled release. Acta Biomater. 2010; 6(10): 3890-8.
    • (2010) Acta Biomater , vol.6 , Issue.10 , pp. 3890-3898
    • Zhang, J.T.1    Keller, T.F.2    Bhat, R.3    Garipcan, B.4    Jandt, K.D.5
  • 34
    • 33645758286 scopus 로고    scopus 로고
    • Development of novel sustained-release system, disintegration-controlled matrix tablet (DCMT) with solid dispersion granules of nilvadipine (II): in vivo evaluation
    • Tanaka N, Imai K, Okimoto K, Ueda S, Tokunaga Y, Ibuki R, et al. Development of novel sustained-release system, disintegration-controlled matrix tablet (DCMT) with solid dispersion granules of nilvadipine (II): in vivo evaluation. J Control Release. 2006; 112(1): 51-6.
    • (2006) J Control Release , vol.112 , Issue.1 , pp. 51-56
    • Tanaka, N.1    Imai, K.2    Okimoto, K.3    Ueda, S.4    Tokunaga, Y.5    Ibuki, R.6
  • 35
    • 0028968166 scopus 로고
    • A simple-model based on first-order kinetics to explain release of highly water-soluble drugs from porous dicalcium phosphate dihydrate matrices
    • Mulye NV, Turco SJ. A simple-model based on first-order kinetics to explain release of highly water-soluble drugs from porous dicalcium phosphate dihydrate matrices. Drug Dev Ind Pharm. 1995; 21(8): 943-53.
    • (1995) Drug Dev Ind Pharm , vol.21 , Issue.8 , pp. 943-953
    • Mulye, N.V.1    Turco, S.J.2
  • 36
    • 84887725686 scopus 로고
    • Dependence of reaction velocity upon surface and agitation: I-theoretical consideration
    • Hixson AW, Crowell JH. Dependence of reaction velocity upon surface and agitation: I-theoretical consideration. Ind Eng Chem. 1931; 23: 923-31.
    • (1931) Ind Eng Chem , vol.23 , pp. 923-931
    • Hixson, A.W.1    Crowell, J.H.2
  • 37
    • 78651077024 scopus 로고    scopus 로고
    • Preparation, in vitro characterization and in vivo release of naproxen loaded in poly-caprolactone nanoparticles
    • Rodrigues MR, Lanzarini CM, Ricci E. Preparation, in vitro characterization and in vivo release of naproxen loaded in poly-caprolactone nanoparticles. Pharm Dev Technol. 2011; 16(1): 12-21.
    • (2011) Pharm Dev Technol , vol.16 , Issue.1 , pp. 12-21
    • Rodrigues, M.R.1    Lanzarini, C.M.2    Ricci, E.3
  • 38
    • 29244474129 scopus 로고    scopus 로고
    • Delivery of the antibiotic gentamicin sulphate from precipitation cast matrices of polycaprolactone
    • Chang HI, Perrie Y, Coombes AG. Delivery of the antibiotic gentamicin sulphate from precipitation cast matrices of polycaprolactone. J Control Release. 2006; 110(2): 414-21.
    • (2006) J Control Release , vol.110 , Issue.2 , pp. 414-421
    • Chang, H.I.1    Perrie, Y.2    Coombes, A.G.3
  • 39
    • 79751484921 scopus 로고    scopus 로고
    • Improving anticancer activity and reducing systemic toxicity of doxorubicin by self-assembled polymeric micelles
    • Gou M, Shi H, Guo G, Men K, Zhang J, Zheng L, et al. Improving anticancer activity and reducing systemic toxicity of doxorubicin by self-assembled polymeric micelles. Nanotechnology. 2011; 22(9): 095102.
    • (2011) Nanotechnology , vol.22 , Issue.9 , pp. 095102
    • Gou, M.1    Shi, H.2    Guo, G.3    Men, K.4    Zhang, J.5    Zheng, L.6
  • 40
    • 34047104570 scopus 로고    scopus 로고
    • Induction of osteoblast differentiation markers in human dermal fibroblasts: potential application to bone tissue engineering
    • Hee CK, Nicoll SB. Induction of osteoblast differentiation markers in human dermal fibroblasts: potential application to bone tissue engineering. Conf Proc IEEE Eng Med Biol Soc. 2006; 1: 521-4.
    • (2006) Conf Proc IEEE Eng Med Biol Soc , vol.1 , pp. 521-524
    • Hee, C.K.1    Nicoll, S.B.2
  • 41
    • 16644401707 scopus 로고    scopus 로고
    • In situ non-invasive spectral discrimination between bone cell phenotypes used in tissue engineering
    • Notingher I, Jell G, Lohbauer U, Salih V, Hench LL. In situ non-invasive spectral discrimination between bone cell phenotypes used in tissue engineering. J Cell Biochem. 2004; 92(6): 1180-92.
    • (2004) J Cell Biochem , vol.92 , Issue.6 , pp. 1180-1192
    • Notingher, I.1    Jell, G.2    Lohbauer, U.3    Salih, V.4    Hench, L.L.5
  • 43
    • 0033961642 scopus 로고    scopus 로고
    • Osteoblast adhesion on biomaterials
    • Anselme K. Osteoblast adhesion on biomaterials. Biomaterials. 2000; 21(7): 667-81.
    • (2000) Biomaterials , vol.21 , Issue.7 , pp. 667-681
    • Anselme, K.1
  • 44
    • 28744438866 scopus 로고    scopus 로고
    • The in vivo degradation, absorption and excretion of PCL-based implant
    • Sun HF, Mei L, Song CX, Cui XM, Wang PY. The in vivo degradation, absorption and excretion of PCL-based implant. Biomaterials. 2006; 27(9): 1735-40.
    • (2006) Biomaterials , vol.27 , Issue.9 , pp. 1735-1740
    • Sun, H.F.1    Mei, L.2    Song, C.X.3    Cui, X.M.4    Wang, P.Y.5
  • 46
    • 0021248678 scopus 로고
    • Effects of chemotherapeutic agents on bone. I. Short-term methotrexate and doxorubicin (adriamycin) treatment in a rat model
    • Friedlaender GE, Tross RB, Doganis AC, Kirkwood JM, Baron R. Effects of chemotherapeutic agents on bone. I. Short-term methotrexate and doxorubicin (adriamycin) treatment in a rat model. J Bone Joint Surg Am. 1984; 66(4): 602-7.
    • (1984) J Bone Joint Surg Am , vol.66 , Issue.4 , pp. 602-607
    • Friedlaender, G.E.1    Tross, R.B.2    Doganis, A.C.3    Kirkwood, J.M.4    Baron, R.5
  • 47
    • 0032887666 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy with doxorubicin and cisplatin in malignant fibrous histiocytoma of bone: a European Osteosarcoma Intergroup study
    • Bramwell VH, Steward WP, Nooij M, Whelan J, Craft AW, Grimer RJ, et al. Neoadjuvant chemotherapy with doxorubicin and cisplatin in malignant fibrous histiocytoma of bone: a European Osteosarcoma Intergroup study. J Clin Oncol. 1999; 17(10): 3260-9.
    • (1999) J Clin Oncol , vol.17 , Issue.10 , pp. 3260-3269
    • Bramwell, V.H.1    Steward, W.P.2    Nooij, M.3    Whelan, J.4    Craft, A.W.5    Grimer, R.J.6
  • 48
    • 0031588180 scopus 로고    scopus 로고
    • Randomised trial of two regimens of chemotherapy in operable osteosarcoma: a study of the European Osteosarcoma Intergroup
    • doi:10.1016/S0140-6736(97)02307-6
    • Souhami RL, Craft AW, van der Eijken JW, Nooij M, Spooner D, Bramwell VH, et al. Randomised trial of two regimens of chemotherapy in operable osteosarcoma: a study of the European Osteosarcoma Intergroup. Lancet. 1997; 350(9082): 911-7.
    • (1997) Lancet , vol.350 , Issue.9082 , pp. 911-917
    • Souhami, R.L.1    Craft, A.W.2    van der Eijken, J.W.3    Nooij, M.4    Spooner, D.5    Bramwell, V.H.6
  • 49
    • 0027082303 scopus 로고
    • A comparison of two short intensive adjuvant chemotherapy regimens in operable osteosarcoma of limbs in children and young adults: the first study of the European Osteosarcoma Intergroup
    • Bramwell VH, Burgers M, Sneath R, Souhami R, van Oosterom AT, Voute PA, et al. A comparison of two short intensive adjuvant chemotherapy regimens in operable osteosarcoma of limbs in children and young adults: the first study of the European Osteosarcoma Intergroup. J Clin Oncol. 1992; 10(10): 1579-91.
    • (1992) J Clin Oncol , vol.10 , Issue.10 , pp. 1579-1591
    • Bramwell, V.H.1    Burgers, M.2    Sneath, R.3    Souhami, R.4    van Oosterom, A.T.5    Voute, P.A.6
  • 50
    • 78649283150 scopus 로고    scopus 로고
    • Bone-targeted doxorubicin-loaded nanoparticles as a tool for the treatment of skeletal metastases
    • Salerno M, Cenni E, Fotia C, Avnet S, Granchi D, Castelli F, et al. Bone-targeted doxorubicin-loaded nanoparticles as a tool for the treatment of skeletal metastases. Curr Cancer Drug Targets. 2010; 10(7): 649-59.
    • (2010) Curr Cancer Drug Targets , vol.10 , Issue.7 , pp. 649-659
    • Salerno, M.1    Cenni, E.2    Fotia, C.3    Avnet, S.4    Granchi, D.5    Castelli, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.