Isoquinoline alkaloids from tinospora cordifolia inhibit rat lens aldose reductase

Phytotherapy Research

Volumn 26, Issue 9, 2012, Pages 1342-1347

  Patel, Mayurkumar B ^a   Mishra, Shrihari ^a  

^a Faculty of Technology and Engineering   (India)

Author keywords

Aldose reductase; cataract; isoquinoline alkaloids; polyol; Tinospora cordifolia

Indexed keywords

ALCOHOL; ALDEHYDE REDUCTASE; GALACTOSE; ISOQUINOLINE ALKALOID; JATRORRHIZINE; MAGNOFLORINE; PALMATINE; POLYOL; QUERCETIN; TINOSPORA CORDIFOLIA EXTRACT;

ANIMAL TISSUE; ARTICLE; CATARACT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME INHIBITION; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; IN VITRO STUDY; MALE; NONHUMAN; OSMOTIC STRESS; PLANT STEM; RAT; TINOSPORA CORDIFOLIA;

ALDEHYDE REDUCTASE; ANIMALS; APORPHINES; BERBERINE; BERBERINE ALKALOIDS; ENZYME INHIBITORS; LENS, CRYSTALLINE; MALE; PLANT EXTRACTS; RATS; RATS, WISTAR; TINOSPORA;

RATTUS; RATTUS NORVEGICUS; TINOSPORA CORDIFOLIA;

EID: 84866131803     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3721     Document Type: Article

References (48)

1. Alper J,. 2000. New insights into type 2 diabetes. Science 289: 37-39.
2. Barbosa-Filho JM, Da-Cunha EVL, Corni-Lio ML, Dias CDS, Gray AI,. 1997. Cissaglaberrimine, An aporphine alkaloid from Cissampelos glaberrima. Phytochemistry 44: 959-961.
3. Baron AD,. 1998. Postprandial hyperglycemia and α-glucosidase inhibitors. Diabetes Res Clin Pract 40: S51-S55.
4. Bisset NG, Nwaiwu J,. 1983. Quaternary alkaloids of Tinospora species. Planta Med 48: 275-279.
5. Dhaliwal KS,. 1999. Method and Composition for Treatment of Diabetes. US Patent 5886029.
6. Fujita T, Ohira K, Miyatake K, Nakana Y, Nakayama M,. 1995. Inhibitory effects of perillosides A and C, and related monoterpene glycosides on aldose reductase and their structure activity relationships. Chem Pharm Bull 43: 920-926.
7. Grover JK, Vats V, Rathi SS,. 2000. Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J Ethnopharmacol 73: 461-470.
8. Grover JK, Vats V, Rathi SS, Dawar R,. 2001. Traditional Indian anti-diabetic plants attenuate progression of renal damage in streptozotocin induced diabetic mice. J Ethnopharmacol 76: 233-238.
9. Grover JK, Yadav S, Vats V,. 2002. Medicinal plants of India with anti-diabetic potential. J Ethnopharmacol 81: 81-100.
10. Gupta SS, Varma SCL, Garg VP, Rai M,. 1967. Antidiabetic effect of Tinospora cordifolia. I. Effect on fasting blood sugar level, glucose tolerence and adrenaline induced hyperglycemia. Indian J Exp Biol 55: 733-745.
11. Guzman A, Guerrero RO,. 2005. Inhibition of aldose reductase by herbs extracts and natural substances and their role in prevention of cataracts. Rev Cubana Plant Med 10: 3-4.
12. Halder N, Joshi S, Gupta SK,. 2003. Lens aldose reductase inhibiting potential of some indigenous plants. J Ethnopharmacol 86: 113-116.
13. Haraguchi H, Ohmi I, Masuda H, et al., 1996a. Inhibition of aldose reductase by dihydroflavonols in Engelhardtia chrysolepis and effects on other enzymes. Experientia 52: 564-567.
14. Haraguchi H, Ohmi I, Sakai S, Fukuda A,. 1996b. Effect of Polygonum hydropiper sulfated flavonoids on lens aldose reductase and related enzymes. J Nat Prod 59: 443-445.
15. Haraguchi H, Kaanada M, Fukuda A,. 1998. An inhibitor of aldose reductase and sorbitol accumulation from Anthocepharus chinensis. Planta Med 64: 68-69.
16. Hayman S, Kinoshita JH,. 1965. Isolation and properties of lens aldose reductase. J Biol Chem 240: 877-882.
17. Heyningen RV,. 1959. Formation of polyols by the lens of the rat with sugar cataract. Nature 184: 194-195.
18. Jung SH, Lee YS, Lim SS, Kim YS, Shin KH,. 2002. Isoflavonoids from the rhizomes of Belamcanda chinensis and their effects on aldose reductase and sorbitol accumulation in streotozotocin induced diabetic rat tissues. Arch Pharm Res 25: 306-312.
19. Kador PF, Robison WG, Kinoshita JH,. 1985. The pharmacology of aldose reductase inhibitors. Ann Rev Pharmacol Toxicol 25: 691-714.
20. Keawpradub N, Dej-adisai S, Yuenyongsawad S,. 2005. Antioxidant and cytotoxic activities of Thai medicinal plants named Khaminkhruea: Arcangelisia flava, Coscinium blumeanum and Fibraurea tinctoria. Songklanakarin J. Sci. Technol. 27 (Suppl. 2): 455-467.
21. Kim MJ, Ahn YJ, Kim MK, Kim HY, Lee HS,. 2001. Rat intestinal α-glucosidase inhibitory activities of leguminous seed extracts. Agric Chem Biotechnol 44: 1-5.
22. Kohda H, Tanaka S, Yamakoa Y, Yahara S, Nohara T, Tanimoto T, et al., 1989. Studies on lens-aldose reductase inhibitor in medicinal Plants. II. Active constituents of Monochasma savatierii Franch. Et Maxim. Chem Pharm Bull 37: 3153-3154.
23. Kumar S, Verma NS, Pande D, Srivastava PS,. 2000. In vitro regeneration and screening of berberine in Tinospora cordifolia. J Med Arom Plant Sci 22: 61.
24. Lee HS,. 2002. Rat lens aldose reductase inhibitory activities of Coptis japonica root-derived isoquinoline alkaloids. J Agric Food Chem 50: 7013.
25. Lee HS, Kim MK,. 2001. Rat intestinal α-glucosidase and lens aldose reductase inhibitory activities of grain extracts. Food Sci Biotechnol 10: 172-177.
26. Lee S, Shim SH, Kim JS, Shin KH, Kang SS,. 2005. Aldose reductase inhibitors from the fruiting bodies of Ganoderma Applanatum. Biol Pharm Bull 28: 1103-1105.
27. Lowry OH, Rosebrough NH, Farr AL, Randall RJ,. 1951. Protein measurement with the folin phenol reagent. J Biol Chem 193: 265-275.
28. Mahajan VR, Jolly CI,. 1985. A new hypoglyceamic agent from Tinospora cordifolia Miers. Indian Drugs 23: 119-120.
29. Matsuda H, Murakami T, Yashiro K, Yamahara J, Yoshikawa M,. 1999. Antidiabetic principles of natural medicines. IV. Aldose reductase and R-glucosidase inhibitors from the roots of Salacia oblonga Wall. (Celastraceae): Structure of a new friedelanetype triterpene, kotalagenin 16-acetate. Chem Pharm Bull 47: 1725-1729.
30. Mooradian AD, Thurman JE,. 1999 Drug therapy of postprandial hyperglycemia. Drugs 57: 19-29.
31. Pachaly P, Schneider C,. 1981. Alkaloids from Tinospora cordifolia Miers. Arch Pharm 314: 251-256.
32. Padhya MA,. 1986. Biosynthesis of isoquinoline alkaloid berberine in tissue cultures of Tinospora cordifolia. Indian Drugs 24: 47-48.
33. Patel MB, Mishra SH,. 2009. Aldose reductase inhibitory activity and anti cataract potential of some traditionally acclaimed antidiabetic medicinal plants. Oriental Pharm Exp Med 9: 245-251.
34. Prince PS, Menon VP,. 1999. Antioxidant activity of Tinospora cordifolia roots in experimental diabetes. J Ethnopharmacol 65: 277-281.
35. Qudrat-I-Khuda M, Khaleque A, Ray N,. 1964. Tinospora cordifolia. I. Constituents of the plant fresh from the field. J Sci Res 1: 177-183.
36. Raghunathan K, Sharma PV,. 1969. The aqueous extract of T. cordifolia caused reduction of blood sugar in alloxan induced hyperglycemic rats and rabbits. J Res Ind Med 3: 203-209.
37. Rosler K, Goodwin RS, Mabry T, Varma SD, Norri J,. 1984. Flavonoids with anti-cataract activity from Brickellia arguta. J Nat Prod 47: 316-319.
38. Sarma DNK, Khosa RL, Sahai M,. 1995. Isolation of jatrorrhizine from Tinospora cordifolia roots. Planta Med 61: 98-99.
39. Sarma DNK, Padma P, Khosa RL,. 1998. Constituents of Tinospora cordifolia root. Fitoterapia 69: 541-542.
40. Shimizu M, Horie S, Arisawa M, et al., 1987. Chemical and pharmaceutical studies on medicinal plants in Paraguay. I. Isolation and identification of lens aldose reductase inhibitor from 'Tapecue' Acanthospermum australe OK. Chem Pharm Bull 35: 1234-1237.
41. Stanely M, Prince P, Menon VP, Gunasekaran G,. 1999. Hypolipidaemic action of Tinospora cordifolia roots in alloxan diabetic rats. J Ethnopharmacol 64: 53-57.
42. Stanely M, Prince P, Menon VP,. 2000. Hypoglycaemic and other related actions of Tinospora cordifolia roots in alloxaninduced diabetic rats. J Ethnopharmacol 70: 9-15.
43. Suryanarayana P, Kumar PA, Saraswat M, Petrash JM, Reddy GB,. 2004. Inhibition of aldose reductase by tannoid principles of Emblica officinalis: implications for the prevention of sugar cataract. Mol Vis 10: 148-154.
44. Ueda H, Kuroiwa E, Tachibana Y, Kawanishi K, Ayala F, Moriyasu M,. 2004. Aldose reductase inhibitors from the leaves of Myrciaria dubia (HB & K) McVaaugh. Phytomedicine 11: 652-656.
45. Wadood N, Wadood A, Shah SA,. 1992. Effect of Tinospora cordifolia on blood glucose and total lipid levels of normal and alloxan-diabetic rabbits. Planta Med 58: 131-136.
46. West CD, Rapoport S,. 1949. Colorimetric method for the estimation of dulcitol. Proc Soc Exp Biol 70: 142-145.
47. Williamson J, Kilo C, Tilton RG,. 1992. Mechanism of glucoseand diabetes-induced vascular dysfunction. In Hyperglycemia,Diabetes, and Vascular Disease, Ruderman N, Williamson J, Brownlee M, (eds). American Physiological Society: New York; 107-132.
48. Yoshikawa M, Shimada H, Norihisa N, et al., 1998. Antidiabetic principles of natural medicines. II. Aldose reductase and R-glucosidase inhibitors from Brazilian natural medicine, the leaves of Myrcia multiflora DC. (Myrtaceae): Structures of myrciacitrins I and II and myrciaphenones A and B. Chem Pharm Bull 46: 113-119.