메뉴 건너뛰기




Volumn 19, Issue 10, 2012, Pages 1689-1697

Signaling crosstalk between TGFβ and Dishevelled/Par1b

Author keywords

development; Smad activation; TGF ; Wnt

Indexed keywords

BONE MORPHOGENETIC PROTEIN; DISHEVELLED 3; DISHEVELLED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; PAR1B PROTEIN; SMAD4 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTIONAL INTERMEDIARY FACTOR 1 GAMMA; TRANSFORMING GROWTH FACTOR BETA; TRIPARTITE MOTIF PROTEIN 33; TRIPARTITE MOTIF PROTEIN 5; UNCLASSIFIED DRUG; WNT5A PROTEIN;

EID: 84866107779     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2012.50     Document Type: Article
Times cited : (9)

References (37)
  • 1
    • 3042737691 scopus 로고    scopus 로고
    • Regionally specific induction by the Spemann-Mangold organizer
    • DOI 10.1038/nrg1347
    • Niehrs C. Regionally specific induction by the Spemann-Mangold organizer. Nat Rev Genet 2004; 5: 425-434. (Pubitemid 38915409)
    • (2004) Nature Reviews Genetics , vol.5 , Issue.6 , pp. 425-434
    • Niehrs, C.1
  • 2
    • 70450187617 scopus 로고    scopus 로고
    • The regulation of TGFbeta signal transduction
    • Moustakas A, Heldin CH. The regulation of TGFbeta signal transduction. Development 2009; 136: 3699-3714.
    • (2009) Development , vol.136 , pp. 3699-3714
    • Moustakas, A.1    Heldin, C.H.2
  • 3
    • 63049136592 scopus 로고    scopus 로고
    • Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis
    • Adorno M, Cordenonsi M, Montagner M, Dupont S, Wong C, Hann B et al. Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell 2009; 137: 87-98.
    • (2009) Cell , vol.137 , pp. 87-98
    • Adorno, M.1    Cordenonsi, M.2    Montagner, M.3    Dupont, S.4    Wong, C.5    Hann, B.6
  • 4
    • 78649982907 scopus 로고    scopus 로고
    • The dynamic roles of TGF-beta in cancer
    • Meulmeester E, Ten Dijke P. The dynamic roles of TGF-beta in cancer. J Pathol 2011; 223: 205-218.
    • (2011) J Pathol , vol.223 , pp. 205-218
    • Meulmeester, E.1    Ten Dijke, P.2
  • 5
    • 58149218252 scopus 로고    scopus 로고
    • Regulating the stability of TGFbeta receptors and Smads
    • Lonn P, Moren A, Raja E, Dahl M, Moustakas A. Regulating the stability of TGFbeta receptors and Smads. Cell Res 2009; 19: 21-35.
    • (2009) Cell Res , vol.19 , pp. 21-35
    • Lonn, P.1    Moren, A.2    Raja, E.3    Dahl, M.4    Moustakas, A.5
  • 6
    • 58149093172 scopus 로고    scopus 로고
    • FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination
    • Dupont S, Mamidi A, Cordenonsi M, Montagner M, Zacchigna L, Adorno M et al. FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination. Cell 2009; 136: 123-135.
    • (2009) Cell , vol.136 , pp. 123-135
    • Dupont, S.1    Mamidi, A.2    Cordenonsi, M.3    Montagner, M.4    Zacchigna, L.5    Adorno, M.6
  • 7
    • 77955753654 scopus 로고    scopus 로고
    • Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo
    • Morsut L, Yan KP, Enzo E, Aragona M, Soligo SM, Wendling O et al. Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo. Development 2010; 137: 2571-2578.
    • (2010) Development , vol.137 , pp. 2571-2578
    • Morsut, L.1    Yan, K.P.2    Enzo, E.3    Aragona, M.4    Soligo, S.M.5    Wendling, O.6
  • 8
    • 0034574602 scopus 로고    scopus 로고
    • The establishment of Spemann's organizer and patterning of the vertebrate embryo
    • De Robertis EM, Larrain J, Oelgeschlager M, Wessely O. The establishment of Spemann's organizer and patterning of the vertebrate embryo. Nat Rev Genet 2000; 1: 171-181.
    • (2000) Nat Rev Genet , vol.1 , pp. 171-181
    • De Robertis, E.M.1    Larrain, J.2    Oelgeschlager, M.3    Wessely, O.4
  • 9
    • 67649109026 scopus 로고    scopus 로고
    • Wnt/Fz signaling and the cytoskeleton: Potential roles in tumorigenesis
    • Lai SL, Chien AJ, Moon RT. Wnt/Fz signaling and the cytoskeleton: potential roles in tumorigenesis. Cell Res 2009; 19: 532-545.
    • (2009) Cell Res , vol.19 , pp. 532-545
    • Lai, S.L.1    Chien, A.J.2    Moon, R.T.3
  • 10
    • 70649099961 scopus 로고    scopus 로고
    • Integration of BMP and Wnt signaling via vertebrate Smad1/5/8 and Drosophila Mad
    • Eivers E, Demagny H, De Robertis EM. Integration of BMP and Wnt signaling via vertebrate Smad1/5/8 and Drosophila Mad. Cytokine Growth Factor Rev 2009; 20: 357-365.
    • (2009) Cytokine Growth Factor Rev , vol.20 , pp. 357-365
    • Eivers, E.1    Demagny, H.2    De Robertis, E.M.3
  • 11
    • 33846688094 scopus 로고    scopus 로고
    • Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker
    • DOI 10.1016/j.molcel.2007.01.006, PII S109727650700010X
    • Sapkota G, Alarcon C, Spagnoli FM, Brivanlou AH, Massague J. Balancing BMP signaling through integrated inputs into the Smad1 linker. Mol Cell 2007; 25: 441-454. (Pubitemid 46199289)
    • (2007) Molecular Cell , vol.25 , Issue.3 , pp. 441-454
    • Sapkota, G.1    Alarcon, C.2    Spagnoli, F.M.3    Brivanlou, A.H.4    Massague, J.5
  • 12
    • 36248995245 scopus 로고    scopus 로고
    • Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal
    • DOI 10.1016/j.cell.2007.09.027, PII S0092867407012160
    • Fuentealba LC, Eivers E, Ikeda A, Hurtado C, Kuroda H, Pera EM et al. Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal. Cell 2007; 131: 980-993. (Pubitemid 350138081)
    • (2007) Cell , vol.131 , Issue.5 , pp. 980-993
    • Fuentealba, L.C.1    Eivers, E.2    Ikeda, A.3    Hurtado, C.4    Kuroda, H.5    Pera, E.M.6    De Robertis, E.M.7
  • 13
    • 27744535862 scopus 로고    scopus 로고
    • The developmental biology of Dishevelled: An enigmatic protein governing cell fate and cell polarity
    • DOI 10.1242/dev.02068
    • Wallingford JB, Habas R. The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity. Development 2005; 132: 4421-4436. (Pubitemid 41632222)
    • (2005) Development , vol.132 , Issue.20 , pp. 4421-4436
    • Wallingford, J.B.1    Habas, R.2
  • 15
    • 0030293782 scopus 로고    scopus 로고
    • Analysis of Dishevelled signalling pathways during Xenopus development
    • Sokol SY. Analysis of Dishevelled signalling pathways during Xenopus development. Curr Biol 1996; 6: 1456-1467. (Pubitemid 27012244)
    • (1996) Current Biology , vol.6 , Issue.11 , pp. 1456-1467
    • Sokol, S.Y.1
  • 16
    • 0034213262 scopus 로고    scopus 로고
    • Beta-catenin signaling activity dissected in the early Xenopus embryo: A novel antisense approach
    • DOI 10.1006/dbio.2000.9720
    • Heasman J, Kofron M, Wylie C. Beta-catenin signaling activity dissected in the early Xenopus embryo: a novel antisense approach. Dev Biol 2000; 222: 124-134. (Pubitemid 30387734)
    • (2000) Developmental Biology , vol.222 , Issue.1 , pp. 124-134
    • Heasman, J.1    Kofron, M.2    Wylie, C.3
  • 17
    • 0037321789 scopus 로고    scopus 로고
    • Chordin is required for the spemann organizer transplantation phenomenon in Xenopus embryos
    • DOI 10.1016/S1534-5807(02)00404-5, PII S1534580702004045
    • Oelgeschlager M, Kuroda H, Reversade B, De Robertis EM. Chordin is required for the Spemann organizer transplantation phenomenon in Xenopus embryos. Dev Cell 2003; 4: 219-230. (Pubitemid 36221798)
    • (2003) Developmental Cell , vol.4 , Issue.2 , pp. 219-230
    • Oelgeschlager, M.1    Kuroda, H.2    Reversade, B.3    De Robertis, E.M.4
  • 18
    • 20144361825 scopus 로고    scopus 로고
    • Subcellular localization and signaling properties of Dishevelled in developing vertebrate embryos
    • DOI 10.1016/j.cub.2005.04.062, PII S0960982205005099
    • Park TJ, Gray RS, Sato A, Habas R, Wallingford JB. Subcellular localization and signaling properties of dishevelled in developing vertebrate embryos. Curr Biol 2005; 15: 1039-1044. (Pubitemid 40772152)
    • (2005) Current Biology , vol.15 , Issue.11 , pp. 1039-1044
    • Tae, J.P.1    Gray, R.S.2    Sato, A.3    Habas, R.4    Wallingford, J.B.5
  • 19
    • 0032529161 scopus 로고    scopus 로고
    • Differential recruitment of dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways
    • Axelrod JD, Miller JR, Shulman JM, Moon RT, Perrimon N. Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes Dev 1998; 12: 2610-2622. (Pubitemid 28406962)
    • (1998) Genes and Development , vol.12 , Issue.16 , pp. 2610-2622
    • Axelrod, J.D.1    Miller, J.R.2    Shulman, J.M.3    Moon, R.T.4    Perrimon, N.5
  • 20
    • 42349093195 scopus 로고    scopus 로고
    • Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors
    • DOI 10.1126/science.1151250
    • Witze ES, Litman ES, Argast GM, Moon RT, Ahn NG. Wnt5a control of cell polarity and directional movement by polarized redistribution of adhesion receptors. Science 2008; 320: 365-369. (Pubitemid 351555657)
    • (2008) Science , vol.320 , Issue.5874 , pp. 365-369
    • Witze, E.S.1    Litman, E.S.2    Argast, G.M.3    Moon, R.T.4    Ahn, N.G.5
  • 22
    • 35549001736 scopus 로고    scopus 로고
    • The PAR proteins: Fundamental players in animal cell polarization
    • DOI 10.1016/j.devcel.2007.10.007, PII S1534580707003851
    • Goldstein B, Macara IG. The PAR proteins: fundamental players in animal cell polarization. Dev Cell 2007; 13: 609-622. (Pubitemid 350011991)
    • (2007) Developmental Cell , vol.13 , Issue.5 , pp. 609-622
    • Goldstein, B.1    Macara, I.G.2
  • 23
    • 19944372081 scopus 로고    scopus 로고
    • Distinct PAR-1 proteins function in different branches of Wnt gignaling during vertebrate development
    • DOI 10.1016/j.devcel.2005.04.011, PII S1534580705001425
    • Ossipova O, Dhawan S, Sokol S, Green JB. Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate development. Dev Cell 2005; 8: 829-841. (Pubitemid 40754055)
    • (2005) Developmental Cell , vol.8 , Issue.6 , pp. 829-841
    • Ossipova, O.1    Dhawan, S.2    Sokol, S.3    Green, J.B.A.4
  • 24
    • 9144231872 scopus 로고    scopus 로고
    • The polarity-inducing kinase Par-1 controls Xenopus gastrulation in cooperation with 14-3-3 and aPKC
    • DOI 10.1038/sj.emboj.7600381
    • Kusakabe M, Nishida E. The polarity-inducing kinase Par-1 controls Xenopus gastrulation in cooperation with 14-3-3 and aPKC. EMBO J 2004; 23: 4190-4201. (Pubitemid 39546157)
    • (2004) EMBO Journal , vol.23 , Issue.21 , pp. 4190-4201
    • Kusakabe, M.1    Nishida, E.2
  • 25
    • 33646876973 scopus 로고    scopus 로고
    • Hematopoiesis controlled by distinct tif1gammma and smad4 branches of the TGFbeta pathway
    • DOI 10.1016/j.cell.2006.03.045, PII S0092867406005186
    • He W, Dorn DC, Erdjument-Bromage H, Tempst P, Moore MA, Massague J. Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway. Cell 2006; 125: 929-941. (Pubitemid 43795187)
    • (2006) Cell , vol.125 , Issue.5 , pp. 929-941
    • He, W.1    Dorn, D.C.2    Erdjument-Bromage, H.3    Tempst, P.4    Moore, M.A.S.5    Massague, J.6
  • 26
    • 33846990139 scopus 로고    scopus 로고
    • Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling
    • Itoh K, Brott BK, Bae GU, Ratcliffe MJ, Sokol SY. Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling. J Biol 2005; 4: 3.
    • (2005) J Biol , vol.4 , pp. 3
    • Itoh, K.1    Brott, B.K.2    Bae, G.U.3    Ratcliffe, M.J.4    Sokol, S.Y.5
  • 27
    • 79959891289 scopus 로고    scopus 로고
    • Recruitment of TIF1gamma to chromatin via its PHD finger-bromodomain activates its ubiquitin ligase and transcriptional repressor activities
    • Agricola E, Randall RA, Gaarenstroom T, Dupont S, Hill CS. Recruitment of TIF1gamma to chromatin via its PHD finger-bromodomain activates its ubiquitin ligase and transcriptional repressor activities. Mol Cell 2011; 43: 85-96.
    • (2011) Mol Cell , vol.43 , pp. 85-96
    • Agricola, E.1    Randall, R.A.2    Gaarenstroom, T.3    Dupont, S.4    Hill, C.S.5
  • 28
    • 34548238145 scopus 로고    scopus 로고
    • Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation
    • DOI 10.1128/MCB.00664-07
    • Levy L, Howell M, Das D, Harkin S, Episkopou V, Hill CS. Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation. Mol Cell Biol 2007; 27: 6068-6083. (Pubitemid 47326695)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.17 , pp. 6068-6083
    • Levy, L.1    Howell, M.2    Das, D.3    Harkin, S.4    Episkopou, V.5    Hill, C.S.6
  • 29
    • 17044365440 scopus 로고    scopus 로고
    • Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase
    • Dupont S, Zacchigna L, Cordenonsi M, Soligo S, Adorno M, Rugge M et al. Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase. Cell 2005; 121: 87-99.
    • (2005) Cell , vol.121 , pp. 87-99
    • Dupont, S.1    Zacchigna, L.2    Cordenonsi, M.3    Soligo, S.4    Adorno, M.5    Rugge, M.6
  • 31
    • 70350785179 scopus 로고    scopus 로고
    • Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling
    • Gao S, Alarcon C, Sapkota G, Rahman S, Chen PY, Goerner N et al. Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling. Mol Cell 2009; 36: 457-468.
    • (2009) Mol Cell , vol.36 , pp. 457-468
    • Gao, S.1    Alarcon, C.2    Sapkota, G.3    Rahman, S.4    Chen, P.Y.5    Goerner, N.6
  • 32
    • 79958265710 scopus 로고    scopus 로고
    • Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast
    • Scheel C, Eaton EN, Li SH, Chaffer CL, Reinhardt F, Kah KJ et al. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell 2011; 145: 926-940.
    • (2011) Cell , vol.145 , pp. 926-940
    • Scheel, C.1    Eaton, E.N.2    Li, S.H.3    Chaffer, C.L.4    Reinhardt, F.5    Kah, K.J.6
  • 33
    • 79959969184 scopus 로고    scopus 로고
    • Antagonistic regulation of EMT by TIF1gamma and Smad4 in mammary epithelial cells
    • Hesling C, Fattet L, Teyre G, Jury D, Gonzalo P, Lopez J et al. Antagonistic regulation of EMT by TIF1gamma and Smad4 in mammary epithelial cells. EMBO Rep 2011; 12: 665-672.
    • (2011) EMBO Rep , vol.12 , pp. 665-672
    • Hesling, C.1    Fattet, L.2    Teyre, G.3    Jury, D.4    Gonzalo, P.5    Lopez, J.6
  • 34
    • 0032101178 scopus 로고    scopus 로고
    • Direct binding of Smad3 and Smad4 to critical TGFbeta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
    • DOI 10.1093/emboj/17.11.3091
    • Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S, Gauthier JM. Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J 1998; 17: 3091-3100. (Pubitemid 28254381)
    • (1998) EMBO Journal , vol.17 , Issue.11 , pp. 3091-3100
    • Dennler, S.1    Itoh, S.2    Vivien, D.3    Dijke, P.T.4    Huet, S.5    Gauthier, J.-M.6
  • 35
    • 0037085441 scopus 로고    scopus 로고
    • Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter
    • DOI 10.1074/jbc.M111023200
    • Korchynskyi O, ten Dijke P. Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter. J Biol Chem 2002; 277: 4883-4891. (Pubitemid 34968524)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.7 , pp. 4883-4891
    • Korchynskyi, O.1    Ten Dijke, P.2
  • 36
    • 40449138006 scopus 로고    scopus 로고
    • Signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation
    • Schlange T, Matsuda Y, Lienhard S, Huber A, Hynes NE, Autocrine WNT. signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation. Breast Cancer Res 2007; 9: R63.
    • (2007) Breast Cancer Res , vol.9
    • Schlange, T.1    Matsuda, Y.2    Lienhard, S.3    Huber, A.4    Hynes, N.E.5    Autocrine, W.N.T.6
  • 37
    • 0037155185 scopus 로고    scopus 로고
    • Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled
    • DOI 10.1074/jbc.M111131200
    • Li L, Mao J, Sun L, Liu W, Wu D. Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled. J Biol Chem 2002; 277: 5977-5981. (Pubitemid 34968379)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.8 , pp. 5977-5981
    • Li, N.1    Mao, J.2    Sun, L.3    Liu, W.4    Wu, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.