Target practice: HDAC inhibitors for schizophrenia

Nature Neuroscience

Volumn 15, Issue 9, 2012, Pages 1180-1181

  Hyman, Steven E ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE; DOPAMINE 2 RECEPTOR; ENTINOSTAT; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE INHIBITOR; HISTONE H3; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR 3; METABOTROPIC RECEPTOR AGONIST; PLACEBO; RISPERIDONE; SEROTONIN 2A RECEPTOR; VORINOSTAT;

CELL DIVISION; CHROMATIN STRUCTURE; DNA SEQUENCE; EPIGENETICS; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENOME; HISTONE ACETYLATION; HUMAN; IMMUNOPRECIPITATION; NERVE CELL PLASTICITY; NONHUMAN; PHASE 2 CLINICAL TRIAL (TOPIC); PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROCESSING; RECEPTOR DOWN REGULATION; SCHIZOPHRENIA; SHORT SURVEY; TRANSCRIPTION INITIATION;

ANIMALS; ANTIPSYCHOTIC AGENTS; HISTONE DEACETYLASE 2; HUMANS; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 84866093614     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3200     Document Type: Short Survey

References (11)

1. Kurita, M. et al. Nat. Neurosci. 15, 1245-1254 (2012).
2. Patil, S.T. et al. Nat. Med. 13, 1102-1107 (2007).
3. Lieberman, J.A. et al. N. Engl. J. Med. 353, 1209-1223 (2005).
4. González-Maeso, J. et al. Nature 452, 93-97 (2008).
5. Maze, I. et al. Neuropsychopharmacology published online, doi:10.1038/npp.2012.124 (25 July 2012)
6. Robison, A.J. & Nestler, E.J. Nat. Rev. Neurosci. 12, 623-637 (2011).
7. Day, J.J. & Sweatt, J.D. Neuron 70, 813-829 (2011).
8. Lewis, D.A. & Levitt, P. Annu. Rev. Neurosci. 25, 409-432 (2002).
9. Nestler, E.J. & Hyman, S.E. Nat. Neurosci. 13, 1161-1169 (2010).
10. Ward, R.D. et al. Neuropsychopharmacology 37, 1699-1707 (2012).
11. Lee, S.H. et al. Nat. Genet. 44, 247-250 (2012).