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Volumn 7, Issue 1, 2012, Pages

Radiation dose ≥54 Gy and CA 19-9 response are associated with improved survival for unresectable, non-metastatic pancreatic cancer treated with chemoradiation

Author keywords

CA 19 9 antigen; Chemotherapy; Pancreas cancer; Radiotherapy dosage

Indexed keywords

CA 19-9 ANTIGEN; CAPECITABINE; DOCETAXEL; FLUOROURACIL; GADOLINIUM TEXAPHYRIN; GEMCITABINE; IRINOTECAN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84866069285     PISSN: None     EISSN: 1748717X     Source Type: Journal    
DOI: 10.1186/1748-717X-7-156     Document Type: Article
Times cited : (19)

References (29)
  • 1
    • 77955635233 scopus 로고    scopus 로고
    • Cancer statistics, 2010.
    • 10.3322/caac.20073, 20610543
    • Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA Cancer J Clin 2010, 60:277-300. 10.3322/caac.20073, 20610543.
    • (2010) CA Cancer J Clin , vol.60 , pp. 277-300
    • Jemal, A.1    Siegel, R.2    Xu, J.3    Ward, E.4
  • 2
    • 0032985541 scopus 로고    scopus 로고
    • Pancreatic cancer: a report of treatment and survival trends for 100,313 patients diagnosed from 1985-1995, using the national cancer database
    • 10.1016/S1072-7515(99)00075-7, 10401733
    • Sener SF, Fremgen A, Menck HR, Winchester DP. Pancreatic cancer: a report of treatment and survival trends for 100,313 patients diagnosed from 1985-1995, using the national cancer database. J Am Coll Surg 1999, 189:1-7. 10.1016/S1072-7515(99)00075-7, 10401733.
    • (1999) J Am Coll Surg , vol.189 , pp. 1-7
    • Sener, S.F.1    Fremgen, A.2    Menck, H.R.3    Winchester, D.P.4
  • 3
    • 43449093718 scopus 로고    scopus 로고
    • Chemoradiotherapy for unresectable pancreatic cancer
    • 10.1007/s10147-007-0763-x, 18463955
    • Ben-Josef E, Lawrence TS. Chemoradiotherapy for unresectable pancreatic cancer. Int J Clin Oncol 2008, 13:121-126. 10.1007/s10147-007-0763-x, 18463955.
    • (2008) Int J Clin Oncol , vol.13 , pp. 121-126
    • Ben-Josef, E.1    Lawrence, T.S.2
  • 4
    • 77955466371 scopus 로고    scopus 로고
    • The role of radiotherapy in locally advanced pancreatic carcinoma
    • 10.1038/nrgastro.2010.98, 20628346
    • Gutt R, Liauw SL, Weichselbaum RR. The role of radiotherapy in locally advanced pancreatic carcinoma. Nat Rev Gastroenterol Hepatol 2010, 7:437-447. 10.1038/nrgastro.2010.98, 20628346.
    • (2010) Nat Rev Gastroenterol Hepatol , vol.7 , pp. 437-447
    • Gutt, R.1    Liauw, S.L.2    Weichselbaum, R.R.3
  • 5
    • 62249176551 scopus 로고    scopus 로고
    • DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer
    • 10.1200/JCO.2008.17.7188, 2668706, 19273710
    • Iacobuzio-Donahue CA, Fu B, Yachida S, Luo M, Abe H, Henderson CM, Vilardell F, Wang Z, Keller JW, Banerjee P, et al. DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer. J Clin Oncol 2009, 27:1806-1813. 10.1200/JCO.2008.17.7188, 2668706, 19273710.
    • (2009) J Clin Oncol , vol.27 , pp. 1806-1813
    • Iacobuzio-Donahue, C.A.1    Fu, B.2    Yachida, S.3    Luo, M.4    Abe, H.5    Henderson, C.M.6    Vilardell, F.7    Wang, Z.8    Keller, J.W.9    Banerjee, P.10
  • 6
    • 0028820160 scopus 로고
    • Hematogenous metastases of pancreatic ductal carcinoma
    • 10.1097/00006676-199511000-00005, 8532650
    • Kamisawa T, Isawa T, Koike M, Tsuruta K, Okamoto A. Hematogenous metastases of pancreatic ductal carcinoma. Pancreas 1995, 11:345-349. 10.1097/00006676-199511000-00005, 8532650.
    • (1995) Pancreas , vol.11 , pp. 345-349
    • Kamisawa, T.1    Isawa, T.2    Koike, M.3    Tsuruta, K.4    Okamoto, A.5
  • 7
    • 33846908072 scopus 로고    scopus 로고
    • Impact of chemoradiotherapy after disease control with chemotherapy in locally advanced pancreatic adenocarcinoma in GERCOR phase II and III studies
    • 10.1200/JCO.2006.07.5663, 17235048
    • Huguet F, Andre T, Hammel P, Artru P, Balosso J, Selle F, Deniaud-Alexandre E, Ruszniewski P, Touboul E, Labianca R, et al. Impact of chemoradiotherapy after disease control with chemotherapy in locally advanced pancreatic adenocarcinoma in GERCOR phase II and III studies. J Clin Oncol 2007, 25:326-331. 10.1200/JCO.2006.07.5663, 17235048.
    • (2007) J Clin Oncol , vol.25 , pp. 326-331
    • Huguet, F.1    Andre, T.2    Hammel, P.3    Artru, P.4    Balosso, J.5    Selle, F.6    Deniaud-Alexandre, E.7    Ruszniewski, P.8    Touboul, E.9    Labianca, R.10
  • 8
    • 0023722682 scopus 로고
    • Treatment of locally unresectable carcinoma of the pancreas: comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone
    • Gastrointestinal Tumor Study Group
    • Gastrointestinal Tumor Study Group Treatment of locally unresectable carcinoma of the pancreas: comparison of combined-modality therapy (chemotherapy plus radiotherapy) to chemotherapy alone. J Natl Cancer Inst 1988, 80:751-755. Gastrointestinal Tumor Study Group.
    • (1988) J Natl Cancer Inst , vol.80 , pp. 751-755
  • 9
    • 80755143456 scopus 로고    scopus 로고
    • Gemcitabine alone versus gemcitabine plus radiotherapy in patients with locally advanced pancreatic cancer: an Eastern Cooperative Oncology Group trial
    • 10.1200/JCO.2011.34.8904, 21969502
    • Loehrer PJ, Feng Y, Cardenes H, Wagner L, Brell JM, Cella D, Flynn P, Ramanathan RK, Crane CH, Alberts SR, Benson AB. Gemcitabine alone versus gemcitabine plus radiotherapy in patients with locally advanced pancreatic cancer: an Eastern Cooperative Oncology Group trial. J Clin Oncol 2011, 29:4105-4112. 10.1200/JCO.2011.34.8904, 21969502.
    • (2011) J Clin Oncol , vol.29 , pp. 4105-4112
    • Loehrer, P.J.1    Feng, Y.2    Cardenes, H.3    Wagner, L.4    Brell, J.M.5    Cella, D.6    Flynn, P.7    Ramanathan, R.K.8    Crane, C.H.9    Alberts, S.R.10    Benson, A.B.11
  • 11
    • 80255123454 scopus 로고    scopus 로고
    • Pretreatment carbohydrate antigen 19-9 level indicates tumor response, early distant metastasis, overall survival, and therapeutic selection in localized and unresectable pancreatic cancer
    • 10.1016/j.ijrobp.2011.02.063, 21600705
    • Yoo T, Lee WJ, Woo SM, Kim TH, Han SS, Park SJ, Moon SH, Shin KH, Kim SS, Hong EK, et al. Pretreatment carbohydrate antigen 19-9 level indicates tumor response, early distant metastasis, overall survival, and therapeutic selection in localized and unresectable pancreatic cancer. Int J Radiat Oncol Biol Phys 2011, 81:e623-e630. 10.1016/j.ijrobp.2011.02.063, 21600705.
    • (2011) Int J Radiat Oncol Biol Phys , vol.81
    • Yoo, T.1    Lee, W.J.2    Woo, S.M.3    Kim, T.H.4    Han, S.S.5    Park, S.J.6    Moon, S.H.7    Shin, K.H.8    Kim, S.S.9    Hong, E.K.10
  • 12
    • 0019410935 scopus 로고
    • Therapy of locally unresectable pancreatic carcinoma: a randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil: The Gastrointestinal Tumor Study Group
    • 10.1002/1097-0142(19811015)48:8<1705::AID-CNCR2820480803>3.0.CO;2-4, 7284971
    • Moertel CG, Frytak S, Hahn RG, O'Connell MJ, Reitemeier RJ, Rubin J, Schutt AJ, Weiland LH, Childs DS, Holbrook MA, et al. Therapy of locally unresectable pancreatic carcinoma: a randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil: The Gastrointestinal Tumor Study Group. Cancer 1981, 48:1705-1710. 10.1002/1097-0142(19811015)48:8<1705::AID-CNCR2820480803>3.0.CO;2-4, 7284971.
    • (1981) Cancer , vol.48 , pp. 1705-1710
    • Moertel, C.G.1    Frytak, S.2    Hahn, R.G.3    O'Connell, M.J.4    Reitemeier, R.J.5    Rubin, J.6    Schutt, A.J.7    Weiland, L.H.8    Childs, D.S.9    Holbrook, M.A.10
  • 13
    • 0345449065 scopus 로고    scopus 로고
    • The role of intraoperative radiotherapy in pancreatic cancer
    • 10.1016/S1055-3207(03)00090-5, 14989127
    • Crane CH, Beddar AS, Evans DB. The role of intraoperative radiotherapy in pancreatic cancer. Surg Oncol Clin N Am 2003, 12:965-977. 10.1016/S1055-3207(03)00090-5, 14989127.
    • (2003) Surg Oncol Clin N Am , vol.12 , pp. 965-977
    • Crane, C.H.1    Beddar, A.S.2    Evans, D.B.3
  • 16
    • 24944476588 scopus 로고    scopus 로고
    • Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer
    • 10.1016/j.ijrobp.2005.07.002, 16168826
    • Koong AC, Christofferson E, Le QT, Goodman KA, Ho A, Kuo T, Ford JM, Fisher GA, Greco R, Norton J, Yang GP. Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer. Int J Radiat Oncol Biol Phys 2005, 63:320-323. 10.1016/j.ijrobp.2005.07.002, 16168826.
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 320-323
    • Koong, A.C.1    Christofferson, E.2    Le, Q.T.3    Goodman, K.A.4    Ho, A.5    Kuo, T.6    Ford, J.M.7    Fisher, G.A.8    Greco, R.9    Norton, J.10    Yang, G.P.11
  • 22
    • 34249283789 scopus 로고    scopus 로고
    • A phase II study of fixed-dose rate gemcitabine plus low-dose cisplatin followed by consolidative chemoradiation for locally advanced pancreatic cancer
    • 10.1016/j.ijrobp.2007.01.005, 17363191
    • Ko AH, Quivey JM, Venook AP, Bergsland EK, Dito E, Schillinger B, Tempero MA. A phase II study of fixed-dose rate gemcitabine plus low-dose cisplatin followed by consolidative chemoradiation for locally advanced pancreatic cancer. Int J Radiat Oncol Biol Phys 2007, 68:809-816. 10.1016/j.ijrobp.2007.01.005, 17363191.
    • (2007) Int J Radiat Oncol Biol Phys , vol.68 , pp. 809-816
    • Ko, A.H.1    Quivey, J.M.2    Venook, A.P.3    Bergsland, E.K.4    Dito, E.5    Schillinger, B.6    Tempero, M.A.7
  • 23
    • 34250829023 scopus 로고    scopus 로고
    • Induction chemotherapy selects patients with locally advanced, unresectable pancreatic cancer for optimal benefit from consolidative chemoradiation therapy
    • 10.1002/cncr.22735, 17538975
    • Krishnan S, Rana V, Janjan NA, Varadhachary GR, Abbruzzese JL, Das P, Delclos ME, Gould MS, Evans DB, Wolff RA, Crane CH. Induction chemotherapy selects patients with locally advanced, unresectable pancreatic cancer for optimal benefit from consolidative chemoradiation therapy. Cancer 2007, 110:47-55. 10.1002/cncr.22735, 17538975.
    • (2007) Cancer , vol.110 , pp. 47-55
    • Krishnan, S.1    Rana, V.2    Janjan, N.A.3    Varadhachary, G.R.4    Abbruzzese, J.L.5    Das, P.6    Delclos, M.E.7    Gould, M.S.8    Evans, D.B.9    Wolff, R.A.10    Crane, C.H.11
  • 25
    • 80052723825 scopus 로고    scopus 로고
    • ATP assay-guided chemosensitivity testing for gemcitabine with biopsy specimens obtained from unresectable pancreatic cancer using endoscopic ultrasonography-guided fine-needle aspiration
    • 10.1007/s10147-011-0197-3, 21331767
    • Wakatsuki T, Irisawa A, Terashima M, Shibukawa G, Takagi T, Imamura H, Takahashi Y, Sato A, Sato M, Ikeda T, et al. ATP assay-guided chemosensitivity testing for gemcitabine with biopsy specimens obtained from unresectable pancreatic cancer using endoscopic ultrasonography-guided fine-needle aspiration. Int J Clin Oncol 2011, 16:387-394. 10.1007/s10147-011-0197-3, 21331767.
    • (2011) Int J Clin Oncol , vol.16 , pp. 387-394
    • Wakatsuki, T.1    Irisawa, A.2    Terashima, M.3    Shibukawa, G.4    Takagi, T.5    Imamura, H.6    Takahashi, Y.7    Sato, A.8    Sato, M.9    Ikeda, T.10
  • 27
    • 0032076257 scopus 로고    scopus 로고
    • Prognostic value of CA 19-9 levels in patients with carcinoma of the pancreas treated with radiotherapy
    • 10.1016/S0360-3016(98)00058-3, 9607356
    • Katz A, Hanlon A, Lanciano R, Hoffman J, Coia L. Prognostic value of CA 19-9 levels in patients with carcinoma of the pancreas treated with radiotherapy. Int J Radiat Oncol Biol Phys 1998, 41:393-396. 10.1016/S0360-3016(98)00058-3, 9607356.
    • (1998) Int J Radiat Oncol Biol Phys , vol.41 , pp. 393-396
    • Katz, A.1    Hanlon, A.2    Lanciano, R.3    Hoffman, J.4    Coia, L.5


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