메뉴 건너뛰기




Volumn 103, Issue 4, 2012, Pages 427-453

The prolonged gastrointestinal syndrome in rhesus macaques: The relationship between gastrointestinal, hematopoietic, and delayed multi-organ sequelae following acute, potentially lethal, partial-body irradiation

Author keywords

biological factors; modeling; radiation damage; radiation dose; radiobiology

Indexed keywords

ACUTE RADIATION SYNDROME; ANIMAL; ARTICLE; CELL SURVIVAL; GASTROINTESTINAL DISEASE; HEMATOPOIETIC STEM CELL; HUMAN; LD 50; MALE; MULTIPLE ORGAN FAILURE; PATHOLOGY; PATHOPHYSIOLOGY; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; RADIATION RESPONSE; RHESUS MONKEY; SURVIVAL; SURVIVAL RATE; WHOLE BODY RADIATION;

EID: 84866053516     PISSN: 00179078     EISSN: None     Source Type: Journal    
DOI: 10.1097/HP.0b013e318266eb4c     Document Type: Article
Times cited : (107)

References (85)
  • 1
    • 0345700759 scopus 로고    scopus 로고
    • Dose response relationships for acute ionizing radiation lethality
    • Anno GH, Young RW, Bloom RM, Mercier JR. Dose response relationships for acute ionizing radiation lethality. Health Phys 84:565-575; 2003.
    • (2003) Health Phys , vol.84 , pp. 565-575
    • Anno, G.H.1    Young, R.W.2    Bloom, R.M.3    Mercier, J.R.4
  • 3
    • 0025370110 scopus 로고
    • Hematological effects of unilateral and bilateral exposures of dogs to 300-kvp x rays
    • Baltschukat K, Nothdurft W. Hematological effects of unilateral and bilateral exposures of dogs to 300-kVp x rays. Radiat Res 123:7-16; 1990.
    • (1990) Radiat Res , vol.123 , pp. 7-16
    • Baltschukat, K.1    Nothdurft, W.2
  • 4
    • 50249168240 scopus 로고    scopus 로고
    • Allogenic bone marrow transplantation after severe, uniform total-body irradiation: Experience from recent (Nyasvizh, Belarus) and previous radiation accidents
    • In: MacVittie TJ, Weiss JF, Browne D, eds. Tarrytown, NY: Pergamon; Elsevier Science Ltd
    • Baranov AE. Allogenic bone marrow transplantation after severe, uniform total-body irradiation: experience from recent (Nyasvizh, Belarus) and previous radiation accidents. In: MacVittie TJ, Weiss JF, Browne D, eds. Advances in the treatment of radiation injuries: advances in the biosciences, Vol. 94. Tarrytown, NY: Pergamon; Elsevier Science Ltd; 1996: 281-293.
    • (1996) Advances in the Treatment of Radiation Injuries: Advances in the Biosciences , vol.94 , pp. 281-293
    • Baranov, A.E.1
  • 6
    • 0027952656 scopus 로고
    • Hematopoietic recovery after 10-gy acute total body radiation
    • Baranov AE, Selidovkin GD, Butturini A, Gale RP. Hematopoietic recovery after 10-Gy acute total body radiation. Blood 83:596-599; 1994.
    • (1994) Blood , vol.83 , pp. 596-599
    • Baranov, A.E.1    Selidovkin, G.D.2    Butturini, A.3    Gale, R.P.4
  • 8
    • 77956396683 scopus 로고    scopus 로고
    • Managing the adverse effects of radiation therapy
    • Berkely FJ. Managing the adverse effects of radiation therapy. AM Fam Physician 82:381-388; 2010.
    • (2010) AM Fam Physician , vol.82 , pp. 381-388
    • Berkely, F.J.1
  • 9
    • 25844497528 scopus 로고    scopus 로고
    • Comparison of autologous cell therapy and granulocyte colony-stimulating factor (g-csf) injection vs. G-csf alone for the treatment of acute radiation syndrome in a nonhuman primate model
    • Bertho JM, Frick J, Prat M, Demarquay C, Dudoignon N, Trompier F, Gorin C, Thierry D, Gourmelon P. Comparison of autologous cell therapy and granulocyte colony-stimulating factor (G-CSF) injection vs. G-CSF alone for the treatment of acute radiation syndrome in a nonhuman primate model. Int J Radiat Oncol Biol Phys 63:911-920; 2005a.
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 911-920
    • Bertho, J.M.1    Frick, J.2    Prat, M.3    Demarquay, C.4    Dudoignon, N.5    Trompier, F.6    Gorin, C.7    Thierry, D.8    Gourmelon, P.9
  • 11
    • 0032897996 scopus 로고    scopus 로고
    • Clonal analysis of mouse intestinal epithelial progeitors
    • Bjerknes M, Cheng H. Clonal analysis of mouse intestinal epithelial progeitors. Gastroenterol 116:7-14; 1999.
    • (1999) Gastroenterol , vol.116 , pp. 7-14
    • Bjerknes, M.1    Cheng, H.2
  • 12
    • 0014167008 scopus 로고
    • A mortality determinant in nonuniform 1exposure of the mammal
    • Bond VP, Robinson CV. A mortality determinant in nonuniform 1exposure of the mammal. Radiat Res 7:265-275; 1967.
    • (1967) Radiat Res , vol.7 , pp. 265-275
    • Bond, V.P.1    Robinson, C.V.2
  • 13
    • 0025942898 scopus 로고
    • Severity of organ injury as a predictor of acute mortality for disparate patterns of absorbed dose distribution
    • Bond VP, Carsten AL, Bullis J, Roth SP. Severity of organ injury as a predictor of acute mortality for disparate patterns of absorbed dose distribution. Radiat Res 128:S9YS11; 1991.
    • (1991) Radiat Res , vol.128
    • Bond, V.P.1    Carsten, A.L.2    Bullis, J.3    Roth, S.P.4
  • 15
    • 0030914867 scopus 로고    scopus 로고
    • Quiescence cycling and turnover in the primitive hematopoietic stem cell compartment
    • Bradford GB, Williams B, Rossi R, Bertoncello I. Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment. Experimental Hematol 25:445-453; 1997.
    • (1997) Experimental Hematol , vol.25 , pp. 445-453
    • Bradford, G.B.1    Williams, B.2    Rossi, R.3    Bertoncello, I.4
  • 18
    • 84856076520 scopus 로고    scopus 로고
    • Ionizing radiation-induced expression of ink4a/arf in murine bone marrow-derived stromal cell populations interferes with bone marrow homeostasis
    • Carbonneau CL, Despars G, Rojas-Sutterlin S, Fortin A, Le O, Hoang T, Beausejour CM. Ionizing radiation-induced expression of INK4a/ARF in murine bone marrow-derived stromal cell populations interferes with bone marrow homeostasis. Blood 119:717-726; 2012.
    • (2012) Blood , vol.119 , pp. 717-726
    • Carbonneau, C.L.1    Despars, G.2    Rojas-Sutterlin, S.3    Fortin, A.4    Le O Hoang, T.5    Beausejour, C.M.6
  • 19
    • 0016325705 scopus 로고
    • Origin, differentiation, and renewal of four main epithelial cell tyoes in the mouse small intestine: 5. Unitarian theory of the origin of the four epithelial cells types
    • Cheng H, Leblond CP. Origin, differentiation, and renewal of four main epithelial cell tyoes in the mouse small intestine: V. Unitarian theory of the origin of the four epithelial cells types. Am J Anat 141:537-561; 1974.
    • (1974) Am J Anat , vol.141 , pp. 537-561
    • Cheng, H.1    Leblond, C.P.2
  • 20
    • 0032980506 scopus 로고    scopus 로고
    • In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells
    • Cheshier SH, Morrison SJ, Liao X, Weissman IL. In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells. Proc Natl Acad Sci 96:3120-3125; 1999.
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 3120-3125
    • Cheshier, S.H.1    Morrison, S.J.2    Liao, X.3    Weissman, I.L.4
  • 22
    • 0014128364 scopus 로고
    • Partial shielding of dogs: Effectiveness of small external epicondylar lead cuffs against lethal x-radiation
    • Cole LJ, Haire HM, Alpen EL. Partial shielding of dogs: effectiveness of small external epicondylar lead cuffs against lethal x-radiation. Radiat Res 32:54-63; 1967.
    • (1967) Radiat Res , vol.32 , pp. 54-63
    • Cole, L.J.1    Haire, H.M.2    Alpen, E.L.3
  • 23
    • 36649017819 scopus 로고
    • Experimental therapy of the gastrointestinal syndrome produced by lethal doses of ionizing radiation
    • Conard RA, Cronkite EP, Brecher G, Strome CPA. Experimental therapy of the gastrointestinal syndrome produced by lethal doses of ionizing radiation. JApplied Physiol 9:227-233; 1956.
    • (1956) J Applied Physiol , vol.9 , pp. 227-233
    • Conard, R.A.1    Cronkite, E.P.2    Brecher, G.3    Strome, C.P.A.4
  • 24
    • 0030690477 scopus 로고    scopus 로고
    • Criteria for the selection of radiation accident victims for stem cell transplantation
    • Densow D, Kindler H, Baranov AE, Tibken B, Hofer EP, Fliedner TM. Criteria for the selection of radiation accident victims for stem cell transplantation. Stem Cells 15(Suppl 2): 287-297; 1997.
    • (1997) Stem Cells , vol.15 , Issue.SUPPL. 2 , pp. 287-297
    • Densow, D.1    Kindler, H.2    Baranov, A.E.3    Tibken, B.4    Hofer, E.P.5    Fliedner, T.M.6
  • 26
    • 0021073636 scopus 로고
    • The expression of early and late damage after thoracic irradiation: A comparison between cba and c57b1 mice
    • Down JD, Steel GG. The expression of early and late damage after thoracic irradiation: a comparison between CBA and C57B1 mice. Radiat Res 96:603-610; 1983.
    • (1983) Radiat Res , vol.96 , pp. 603-610
    • Down, J.D.1    Steel, G.G.2
  • 28
    • 0004116672 scopus 로고
    • Cambridge UK: Cambridge University Press
    • Finney DJ. Probit analysis. Cambridge, UK: Cambridge University Press; 1947.
    • (1947) Probit Analysis
    • Finney, D.J.1
  • 29
    • 33947208052 scopus 로고    scopus 로고
    • Pathophysiological principles underlying the blood cell concentration responses used to assess the severity of effect after accidental whole-body radiation exposure: An essential basis for evidence-based clinical triage
    • Fliedner TM, Graessle D, Meineke V, Dorr H. Pathophysiological principles underlying the blood cell concentration responses used to assess the severity of effect after accidental whole-body radiation exposure: an essential basis for evidence-based clinical triage. Exp Hematol 35:8-16; 2007.
    • (2007) Exp Hematol , vol.35 , pp. 8-16
    • Fliedner, T.M.1    Graessle, D.2    Meineke, V.3    Dorr, H.4
  • 30
    • 0025793783 scopus 로고    scopus 로고
    • The genetic basis of strain-dependent differences in the early phase of radiation injury in mouse lung
    • Franko AJ. The genetic basis of strain-dependent differences in the early phase of radiation injury in mouse lung. Radiat Res 126:349-356; 2010.
    • (2010) Radiat Res , vol.126 , pp. 349-356
    • Franko, A.J.1
  • 31
    • 0018131348 scopus 로고
    • Radiation pneumonitis: Experience following a large single dose of radiation
    • Fryer CJHFPJ, Rider WD, Poon P. Radiation pneumonitis: experience following a large single dose of radiation. Int J Radiat Oncol Biol Phys 4:931-936; 1978.
    • (1978) Int J Radiat Oncol Biol Phys , vol.4 , pp. 931-936
    • Cjhfpj, F.1    Rider, W.D.2    Poon, P.3
  • 32
    • 77952007213 scopus 로고    scopus 로고
    • European consensus on the medical management of acute radiation syndrome and analysis of the radiation accidents in belgium and senegal
    • Gourmelon P, Benderitter M, Bertho J-M, Gorin NC, De Revel P. European consensus on the medical management of acute radiation syndrome and analysis of the radiation accidents in Belgium and Senegal. Health Phys 98:825-832; 2010.
    • (2010) Health Phys , vol.98 , pp. 825-832
    • Gourmelon, P.1    Benderitter, M.2    Bertho, J.-M.3    Gorin, N.C.4    De Revel, P.5
  • 33
    • 0018856358 scopus 로고
    • Radiation pneumonitis in mice. Some effects of corticosteroids on morality and pulmonary physiology
    • Gross NJ. Radiation pneumonitis in mice. Some effects of corticosteroids on morality and pulmonary physiology. J Clin Invest 66:504-510; 1980.
    • (1980) J Clin Invest , vol.66 , pp. 504-510
    • Gross, N.J.1
  • 34
    • 0023840306 scopus 로고
    • Protective effect of corticosteroids on radiation pneumonitis in mice
    • Gross NJ, Narine KR, Wade R. Protective effect of corticosteroids on radiation pneumonitis in mice. Radiat Res 113: 112-119; 1988.
    • (1988) Radiat Res , vol.113 , pp. 112-119
    • Gross, N.J.1    Narine, K.R.2    Wade, R.3
  • 35
    • 84866028123 scopus 로고
    • Acute effects of radiation exposure following the chernobyl accident immediate results of radiation sickness and outcome of treatment
    • In: Browne D Weiss JF MacVittie TJ Pillai MV Eds. New York: Plenum Press
    • Guskova AK, Nadezhina NM, Barabanova AV, Baranov AE, Gusev IA, Protasova TG, Boguslavskij VB, Pokrovskaya VN. Acute effects of radiation exposure following the Chernobyl accident, immediate results of radiation sickness and outcome of treatment. In: Browne D, Weiss JF, MacVittie TJ, Pillai MV, eds. Treatment of radiation injuries. New York: Plenum Press; 1990: 195-209.
    • (1990) Treatment Of Radiation Injuries , pp. 195-209
    • Guskova, A.K.1    Nadezhina, N.M.2    Barabanova, A.V.3    Baranov, A.E.4    Gusev, I.A.5    Protasova, T.G.6    Boguslavskij, V.B.7    Pokrovskaya, V.N.8
  • 38
    • 33749175256 scopus 로고    scopus 로고
    • Radiation effects on the respiratory system
    • Hill RP. Radiation effects on the respiratory system. Brit J Radiol 27:81; 2005.
    • (2005) Brit J Radiol , vol.27 , pp. 81
    • Hill, R.P.1
  • 42
    • 84912334933 scopus 로고
    • Effectiveness of transfusions of fresh and lyophiloized platelets in controlling bleeding due to thrombocytopenia
    • Jackson DP, Sorensen DK, Cronkite EP, Bond VP, Fliedner TM. Effectiveness of transfusions of fresh and lyophiloized platelets in controlling bleeding due to thrombocytopenia. J Clinical Investigation 38:1689-1697; 1959.
    • (1959) J Clinical Investigation , vol.38 , pp. 1689-1697
    • Jackson, D.P.1    Sorensen, D.K.2    Cronkite, E.P.3    Bond, V.P.4    Fliedner, T.M.5
  • 43
    • 35548936968 scopus 로고    scopus 로고
    • A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche
    • Jang Y-Y, Sharkis SJ. A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche. Blood 110:3056-3063; 2007.
    • (2007) Blood , vol.110 , pp. 3056-3063
    • Jang, Y.-Y.1    Sharkis, S.J.2
  • 44
    • 84863230213 scopus 로고    scopus 로고
    • Intact function of lgr5 receptor-expressing intestinal stem cells in the absence of paneth cells
    • Kim T-H, Escudero S, Shivdasani RA. Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of paneth cells. PNAS 109:3932-3937; 2012.
    • (2012) PNAS , vol.109 , pp. 3932-3937
    • Kim, T.-H.1    Escudero, S.2    Shivdasani, R.A.3
  • 45
    • 66149169115 scopus 로고    scopus 로고
    • Multiple organ involvment and failure: Selected russian radiation accident cases re-visited
    • Konchalovsky MV, Baranov AE, Kolganov AV. Multiple organ involvment and failure: selected Russian radiation accident cases re-visited. Br J Radiol 78:26-29; 2005.
    • (2005) Br J Radiol , vol.78 , pp. 26-29
    • Konchalovsky, M.V.1    Baranov, A.E.2    Kolganov, A.V.3
  • 46
    • 66149169115 scopus 로고    scopus 로고
    • Multiple organ involvement and failure: Selected russian radiation accident cases re-visited
    • Konchalovsky MV. Multiple organ involvement and failure: selected Russian radiation accident cases re-visited. BJR Supplement/ BIR 27:26-29; 2010.
    • (2010) BJR Supplement/BIR , vol.27 , pp. 26-29
    • Konchalovsky, M.V.1
  • 47
    • 0029154941 scopus 로고
    • Damage and morbidity from pneumonitis after irradiation of partial volumes of mouse lung
    • Liao ZX, Travis EL, Tucker SL. Damage and morbidity from pneumonitis after irradiation of partial volumes of mouse lung. Int J Radiat Oncol Biol Phys 32:1359-1370; 1995.
    • (1995) Int J Radiat Oncol Biol Phys , vol.32 , pp. 1359-1370
    • Liao, Z.X.1    Travis, E.L.2    Tucker, S.L.3
  • 48
    • 0021366383 scopus 로고
    • Radiation-induced pulmonary change: Ct findings
    • Libshitz HI, Shuman LS. Radiation-induced pulmonary change: CT findings. J Comput Assit Tomogr 8:15-19; 1984.
    • (1984) J Comput Assit Tomogr , vol.8 , pp. 15-19
    • Libshitz, H.I.1    Shuman, L.S.2
  • 49
    • 38949162931 scopus 로고    scopus 로고
    • Clinical report of three cases of acute radiation sickness from a 60co radiation accident in henan province in china
    • Liu Q, Jiang B, Jiang L-P, Wu Y, Wang X-G, Zhao F-L, Fu B-H, Turai I, Jiang E. Clinical report of three cases of acute radiation sickness from a 60Co radiation accident in Henan province in China. J Radiat Res 49:63-69; 2008.
    • (2008) J Radiat Res , vol.49 , pp. 63-69
    • Liu, Q.1    Jiang, B.2    Jiang, L.-P.3    Wu, Y.4    Wang, X.-G.5    Zhao, F.-L.6    Fu, B.-H.7    Turai, I.8    Jiang, E.9
  • 50
    • 0026049793 scopus 로고
    • The relative biological effectiveness of mixed fissionneutron: Gamma radiation on the hematopoietic syndrome in the canine: Effect of therapy on survival
    • MacVittie TJ, Monroy R, Vigneulle RM, Zeman GH, Jackson WE. The relative biological effectiveness of mixed fissionneutron: gamma radiation on the hematopoietic syndrome in the canine: effect of therapy on survival. Radiat Res 128: S29-S36; 1991.
    • (1991) Radiat Res , vol.128
    • MacVittie, T.J.1    Monroy, R.2    Vigneulle, R.M.3    Zeman, G.H.4    Jackson, W.E.5
  • 51
    • 26844474422 scopus 로고    scopus 로고
    • Consensus summary on the treatment of radiation injuries
    • In: MacVittie TJ Weiss JF Browne D Eds. Tarrytown NY: Pergamon, Elsevier Sciences Inc.
    • MacVittie TJ, Weiss JF, Browne D. Consensus summary on the treatment of radiation injuries. In: MacVittie TJ, Weiss JF, Browne D, eds. Advances in the treatment of radiation injuries. Tarrytown, NY: Pergamon, Elsevier Sciences Inc.; 1996: 325-346.
    • (1996) Advances In The Treatment Of Radiation Injuries , pp. 325-346
    • MacVittie, T.J.1    Weiss, J.F.2    Browne, D.3
  • 52
    • 26844521492 scopus 로고    scopus 로고
    • Defining the full therapeutic potential of recombinant growth factors in the post radiation-accident environment: The effect of supportive care plus administration of g-csf
    • MacVittie TJ, Farese AM, Jackson WI. Defining the full therapeutic potential of recombinant growth factors in the post radiation-accident environment: the effect of supportive care plus administration of G-CSF. Health Phys 89:546-555; 2005.
    • (2005) Health Phys , vol.89 , pp. 546-555
    • MacVittie, T.J.1    Farese, A.M.2    Jackson, W.I.3
  • 55
  • 57
    • 0024601562 scopus 로고
    • Comparison of the gastrointestinal syndrome after total-body or total-abdominal irradiation
    • Mason KA, Withers HR, McBride WH, Davis CA, Smathers JB. Comparison of the gastrointestinal syndrome after total-body or total-abdominal irradiation. Radiat Res 117:480-488; 1989.
    • (1989) Radiat Res , vol.117 , pp. 480-488
    • Mason, K.A.1    Withers, H.R.2    McBride, W.H.3    Davis, C.A.4    Smathers, J.B.5
  • 58
    • 33751099906 scopus 로고    scopus 로고
    • Radiation-induced multi-organ involvement and failure: Challenges for radiation accident medical management and future research
    • Meineke V, Fliedner TM. Radiation-induced multi-organ involvement and failure: challenges for radiation accident medical management and future research. Br J Radiol 27(Suppl): 196-200; 2005.
    • (2005) Br J Radiol , vol.27 , Issue.SUPPL. , pp. 196-200
    • Meineke, V.1    Fliedner, T.M.2
  • 59
    • 0023813251 scopus 로고
    • Recovery from severe hemopoietic suppression using recombinant human granulocyte-macrophage colony stimulating factor
    • Monroy RL, Skelly RR, Taylor P, Dubois A, Donahue RE, MacVittie TJ. Recovery from severe hemopoietic suppression using recombinant human granulocyte-macrophage colony stimulating factor. Experimental Hematol 16:334-338; 1988.
    • (1988) Experimental Hematol , vol.16 , pp. 334-338
    • Monroy, R.L.1    Skelly, R.R.2    Taylor, P.3    Dubois, A.4    Donahue, R.E.5    MacVittie, T.J.6
  • 60
    • 39149144034 scopus 로고    scopus 로고
    • Stem cells and niches: Mechanisms that promote stem cell maintenanace throughout life
    • Morrison SJ, Spradling AC. Stem cells and niches: mechanisms that promote stem cell maintenanace throughout life. Cell 132:598-611; 2008.
    • (2008) Cell , vol.132 , pp. 598-611
    • Morrison, S.J.1    Spradling, A.C.2
  • 61
    • 0027473628 scopus 로고
    • Evaluation of isoeffect formulae for predicting radiation-induced lung damage
    • Newcomb CH, Van Dyk J, Hill RP. Evaluation of isoeffect formulae for predicting radiation-induced lung damage. Radiother Oncol 26:51-63; 1993.
    • (1993) Radiother Oncol , vol.26 , pp. 51-63
    • Newcomb, C.H.1    Van Dyk, J.2    Hill, R.P.3
  • 62
    • 20244377491 scopus 로고
    • The regenerative ability of hemopoietic tissue following lethal x-irradiation in dogs
    • Perman V, Cronkite EP, Bond VP, Sorensen DK. The regenerative ability of hemopoietic tissue following lethal x-irradiation in dogs. Blood 19:724-737; 1962.
    • (1962) Blood , vol.19 , pp. 724-737
    • Perman, V.1    Cronkite, E.P.2    Bond, V.P.3    Sorensen, D.K.4
  • 63
    • 84989436823 scopus 로고
    • Continuous labeling studies on mouse skin and intestine
    • Potten CS. Continuous labeling studies on mouse skin and intestine. Cell Tissue Kinet 7:271-283; 1974.
    • (1974) Cell Tissue Kinet , vol.7 , pp. 271-283
    • Potten, C.S.1
  • 64
    • 0017739418 scopus 로고
    • Extreme sensitivity of some intestinal crypt cells to x irradiation
    • Potten CS. Extreme sensitivity of some intestinal crypt cells to X irradiation. Nature 269:518-521; 1977.
    • (1977) Nature , vol.269 , pp. 518-521
    • Potten, C.S.1
  • 66
    • 0015393582 scopus 로고
    • Radiation protection by tibia-shielding in adult, weanling and suckling mice
    • Rauchwerger M. Radiation protection by tibia-shielding in adult, weanling and suckling mice. Int J Radiat Biol 22: 269-278; 1972.
    • (1972) Int J Radiat Biol , vol.22 , pp. 269-278
    • Rauchwerger, M.1
  • 68
    • 46249128798 scopus 로고    scopus 로고
    • Bmi 1 is expressed in vivo in intestinal stem cells
    • Sangiorgi E, Capecchi MR. Bmi 1 is expressed in vivo in intestinal stem cells. Nat Genet 40:915-920; 2008.
    • (2008) Nat Genet , vol.40 , pp. 915-920
    • Sangiorgi, E.1    Capecchi, M.R.2
  • 69
    • 33745635043 scopus 로고    scopus 로고
    • The stem-cell niche as an entity of action
    • Scadden DT. The stem-cell niche as an entity of action. Nature 441:1075-1079; 2006.
    • (2006) Nature , vol.441 , pp. 1075-1079
    • Scadden, D.T.1
  • 70
    • 84965083504 scopus 로고
    • Water-electrolyte and antibiotic therapy against acute (3 to 5 day) intestinal radiation death in the rat
    • Taketa ST. Water-electrolyte and antibiotic therapy against acute (3 to 5 day) intestinal radiation death in the rat. Radiat Res 16:312-326; 1962.
    • (1962) Radiat Res , vol.16 , pp. 312-326
    • Taketa, S.T.1
  • 71
    • 70449257817 scopus 로고
    • Modification of radiation injury in rats through gastrointestinal tract shielding and bone marrow therapy
    • Taketa TS, Swift MN, Bond VP. Modification of radiation injury in rats through gastrointestinal tract shielding and bone marrow therapy. Am J Physiol 196:987-992; 1959.
    • (1959) Am J Physiol , vol.196 , pp. 987-992
    • Taketa, T.S.1    Swift, M.N.2    Bond, V.P.3
  • 73
    • 0024427204 scopus 로고
    • The influence of bone marrow depletion on intestinal radiation damage
    • Terry NH, Travis EL. The influence of bone marrow depletion on intestinal radiation damage. International J Radiat Oncol Biol Phys 17:569-573; 1989.
    • (1989) International J Radiat Oncol Biol Phys , vol.17 , pp. 569-573
    • Terry, N.H.1    Travis, E.L.2
  • 74
    • 0001413705 scopus 로고
    • Marrow transplants in lethally irradiated dogs given methotrexate
    • Thomas ED, Collins JA, Herman EC Jr, Ferrebee JW. Marrow transplants in lethally irradiated dogs given methotrexate. Blood 19:217-228; 1962.
    • (1962) Blood , vol.19 , pp. 217-228
    • Thomas, E.D.1    Collins, J.A.2    Herman Jr., E.C.3    Ferrebee, J.W.4
  • 75
    • 80054041585 scopus 로고    scopus 로고
    • A reserve stem cell population in small intestine renders lgr5-positive cells dispensable
    • Tian H, Biehs B, Warming S, Leong KG, Rangell L, Klein OD, de Sauvage FJ. A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. Nature 478: 255-260; 2011.
    • (2011) Nature , vol.478 , pp. 255-260
    • Tian, H.1    Biehs, B.2    Warming, S.3    Leong, K.G.4    Rangell, L.5    Klein, O.D.6    De Sauvage, F.J.7
  • 76
    • 0031890351 scopus 로고    scopus 로고
    • Proliferation-induced decline of primative hematopoietic progenitor cell activity is coupled with an increase in apoptosis in ex vivo expanded cd34+ cells
    • Traycoff CM, Orazi A, Ladd AC, Rice S, McMahel J, Srour EF. Proliferation-induced decline of primative hematopoietic progenitor cell activity is coupled with an increase in apoptosis in ex vivo expanded CD34+ cells. Experimental Hematol 26: 53-62; 1998.
    • (1998) Experimental Hematol , vol.26 , pp. 53-62
    • Traycoff, C.M.1    Orazi, A.2    Ladd, A.C.3    Rice, S.4    McMahel, J.5    Srour, E.F.6
  • 77
    • 0026070244 scopus 로고
    • Radiation sensitivity of the hemopoietic stem cell
    • van Bekkum DW. Radiation sensitivity of the hemopoietic stem cell. Radiat Res 128:S4YS8; 1991.
    • (1991) Radiat Res , vol.128
    • Van Bekkum, D.W.1
  • 78
    • 0019431047 scopus 로고
    • Radiation pneumonitis following large single dose irradiation: A reevaluation based on absolute dose to lung
    • Van Dyk J, Keane TJ, Kan S, Rider WD, Fryer CJ. Radiation pneumonitis following large single dose irradiation: a reevaluation based on absolute dose to lung. Int J Radiat Oncol Biol Phys 7:461-467; 1981.
    • (1981) Int J Radiat Oncol Biol Phys , vol.7 , pp. 461-467
    • Van Dyk, J.1    Keane, T.J.2    Kan, S.3    Rider, W.D.4    Fryer, C.J.5
  • 80
    • 0026070245 scopus 로고
    • The response of dogs to mixed neutron-g radiation with different ng ratios
    • Wang J,Wang B, Chen D, Luo Y. The response of dogs to mixed neutron-g radiation with different n/g ratios. Radiat Res 128: S42-S46; 1991.
    • (1991) Radiat Res , vol.128
    • Wang, J.1    Wang, B.2    Chen, D.3    Luo, Y.4
  • 81
    • 72649103214 scopus 로고    scopus 로고
    • Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells
    • WangY, Liu L, Pazhanisamy SK, Li H, Meng A, Zhou D. Total body irradiation causes residual bone marrow injury by induction of persistent oxidative stress in murine hematopoietic stem cells. Free Radical Biol Medicine 48:348-356; 2010.
    • (2010) Free Radical Biol Medicine , vol.48 , pp. 348-356
    • WangY Liu, L.1    Pazhanisamy, S.K.2    Li, H.3    Meng, A.4    Zhou, D.5
  • 82
    • 0013902682 scopus 로고
    • Changes in the villous pattern of the human jejunum associated with heavy radiation damage
    • Wiernik G. Changes in the villous pattern of the human jejunum associated with heavy radiation damage. Gut 7:149-153; 1966a.
    • (1966) Gut , vol.7 , pp. 149-153
    • Wiernik, G.1
  • 83
    • 0014013894 scopus 로고
    • In-vivo cell kinetics of a normal human tissue
    • Wiernik G. In-vivo cell kinetics of a normal human tissue. Brit Med J 2:385-387; 1966b.
    • (1966) Brit Med J , vol.2 , pp. 385-387
    • Wiernik, G.1
  • 84
    • 0013899620 scopus 로고
    • Radiation damage and repair in the human jejunal mucosa
    • Wiernik G. Radiation damage and repair in the human jejunal mucosa. J Pathol 91:389-393; 1966c.
    • (1966) J Pathol , vol.91 , pp. 389-393
    • Wiernik, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.