Crystallographic Study of Novel Transthyretin Ligands Exhibiting Negative-Cooperativity between Two Thyroxine Binding Sites

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Tomar, Divya ^a   Khan, Tarique ^a   Singh, Rajiv Ranjan ^a   Mishra, Satyendra ^a   Gupta, Sarika ^a   Surolia, Avadhesha ^a,b   Salunke, Dinakar M ^a,c  

^a NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

^b INDIAN INSTITUTE OF SCIENCE   (India)

^c REGIONAL CENTRE FOR BIOTECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BIPHENYL ETHER DERIVATIVE; ETHER DERIVATIVE; PREALBUMIN; SERINE; TETRAMER; THYROXINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CRYSTAL STRUCTURE; DISSOCIATION; HYDROGEN BOND; IMAGE ANALYSIS; LIGAND BINDING; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; STEROID BINDING; WATER RETENTION; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHENYL ETHERS; PREALBUMIN; PROTEIN BINDING; PROTEIN STABILITY; THYROXINE;

EID: 84866051945     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043522     Document Type: Article

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