Armodafinil and modafinil in patients with excessive sleepiness associated with shift work disorder: A pharmacokinetic/pharmacodynamic model for predicting and comparing their concentration-effect relationships

Journal of Clinical Pharmacology

Volumn 52, Issue 9, 2012, Pages 1328-1342

  Darwish, Mona ^a   Bond, Mary ^a   Ezzet, Farkad ^b  

^a Cephalon Inc   (United States)

^b Strategic Consulting Services   (United States)

Author keywords

Armodafinil; modafinil; pharmacokinetic pharmacodynamic modeling; population pharmacokinetics; shift work disorder

Indexed keywords

ARMODAFINIL; MODAFINIL; PLACEBO;

ARTICLE; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG RESPONSE; HUMAN; PLASMA CONCENTRATION-TIME CURVE; RANDOMIZED CONTROLLED TRIAL (TOPIC); SHIFT WORKER; SLEEP; SOMNOLENCE; STATISTICAL MODEL; TIME; WAKEFULNESS;

BENZHYDRYL COMPOUNDS; CENTRAL NERVOUS SYSTEM STIMULANTS; DOUBLE-BLIND METHOD; HUMANS; MODELS, BIOLOGICAL; SLEEP DISORDERS, CIRCADIAN RHYTHM; WAKEFULNESS;

EID: 84866051856     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1177/0091270011417825     Document Type: Article

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