Does Augmentation with Alpha1-Antitrypsin Affect Neutrophil Extracellular Traps Formation?

International Journal of Biological Sciences

Volumn 8, Issue 7, 2012, Pages 1023-1025

  Frenzel, Eileen ^a,b   Korenbaum, Elena ^a,b   Hegermann, Jan ^a,b   Ochs, Matthias ^a,b   Koepke, Janine ^a,b   Koczulla, Andreas Rembert ^a,b   Welte, Tobias ^a,b   Köhnlein, Thomas ^a,b   Janciauskiene, Sabina ^a,b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN;

AGED; ARTICLE; BLOOD; CHRONIC OBSTRUCTIVE LUNG DISEASE; FEMALE; HUMAN; NEUTROPHIL; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

AGED; ALPHA 1-ANTITRYPSIN; FEMALE; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; NEUTROPHILS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 84866047357     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.4701     Document Type: Article

References (5)

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2. Nauseef WM. How human neutrophils kill and degrade microbes: an integrated view. Immunol Rev. 2007; 219: 883.
3. Marcos V, Zhou Z, Yildirim AO, et al. CXCR2 mediates NADPH oxi-dase-independent neutrophil extracellular trap formation in cystic fi-brosis airway inflammation. Nat Med. 2010; 16: 1018-23.
4. Bucurenci N, Blake DR, Chidwick K, et al. Inhibition of neutrophil su-peroxide production by human plasma alpha 1-antitrypsin. FEBS Lett. 1992; 300: 21-4.
5. Stockley RA, Parr DG, Piitulainen E, et al. Therapeutic efficacy of α-1 antitrypsin augmentation therapy on the loss of lung tissue: an inte-grated analysis of 2 randomised clinical trials using computed tomog-raphy densitometry. Respir Res. 2010; 5: 136.