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Volumn 107, Issue 10, 2012, Pages 1837-1844

Medicinal Δ 9-tetrahydrocannabinol (dronabinol) impairs on-the-road driving performance of occasional and heavy cannabis users but is not detected in Standard Field Sobriety Tests

Author keywords

9 tetrahydrocannabinol; Cannabis; Driving; Dronabinol; DUID; SFST; THC

Indexed keywords

PSYCHOTROPIC AGENT; TETRAHYDROCANNABINOL;

EID: 84866045303     PISSN: 09652140     EISSN: 13600443     Source Type: Journal    
DOI: 10.1111/j.1360-0443.2012.03928.x     Document Type: Article
Times cited : (101)

References (26)
  • 1
    • 84866040842 scopus 로고    scopus 로고
    • Substance Abuse and Mental Health Services Administration (SAMHSA). Results from the 2008 National Survey on Drug Use and Health: National Findings. NSDUH Series H-36, HHS Publication no. SMA 09-4434. Rockville, MD: Office of Applied Studies
    • Substance Abuse and Mental Health Services Administration (SAMHSA). Results from the 2008 National Survey on Drug Use and Health: National Findings. NSDUH Series H-36, HHS Publication no. SMA 09-4434. Rockville, MD: Office of Applied Studies; 2009.
    • (2009)
  • 2
    • 84866033417 scopus 로고    scopus 로고
    • 2007 National Roadside Survey of Alcohol and Drug Use by Drivers: Drug Results (DOT HS 811 249). Washington: US Department of Transportation, National Highway Traffic Safety Administration.
    • Lacey J. H., Kelley-Baker T., Furr-Holden D., Voas E. B., Romano E., Ramirez A. etal. 2007 National Roadside Survey of Alcohol and Drug Use by Drivers: Drug Results (DOT HS 811 249). Washington: US Department of Transportation, National Highway Traffic Safety Administration. 2009.
    • (2009)
    • Lacey, J.H.1    Kelley-Baker, T.2    Furr-Holden, D.3    Voas, E.B.4    Romano, E.5    Ramirez, A.6
  • 3
    • 84866040841 scopus 로고    scopus 로고
    • National Highway Traffic Safety Administration (NHTSA). FARS data query. Available at (accessed 17 June 2012).
    • National Highway Traffic Safety Administration (NHTSA). FARS data query. 2009. Available at http://www-fars.nhtsa.dot.gov/Main/index.aspx (accessed 17 June 2012).
    • (2009)
  • 7
    • 33645740221 scopus 로고    scopus 로고
    • Pharmacokinetics of cannabinoids
    • McGilveray I. J. Pharmacokinetics of cannabinoids. Pain Res Manag 2005; 10: 15A-22A.
    • (2005) Pain Res Manag , vol.10
    • McGilveray, I.J.1
  • 9
    • 65349097881 scopus 로고    scopus 로고
    • Neurocognitive performance during acute THC intoxication in heavy and occasional cannabis users
    • Ramaekers J. G., Kauert G., Theunissen E. L., Toennes S. W., Moeller M. R. Neurocognitive performance during acute THC intoxication in heavy and occasional cannabis users. J Psychopharmacol 2009; 23: 266-277.
    • (2009) J Psychopharmacol , vol.23 , pp. 266-277
    • Ramaekers, J.G.1    Kauert, G.2    Theunissen, E.L.3    Toennes, S.W.4    Moeller, M.R.5
  • 10
    • 50649086574 scopus 로고    scopus 로고
    • Tolerability and effects of oral Delta9-tetrahydrocannabinol in older adolescents with marijuana use disorders
    • Gray K. M., Hart C. L., Christie D. K., Upadhyaya H. P. Tolerability and effects of oral Delta9-tetrahydrocannabinol in older adolescents with marijuana use disorders. Pharmacol Biochem Behav 2008; 91: 67-70.
    • (2008) Pharmacol Biochem Behav , vol.91 , pp. 67-70
    • Gray, K.M.1    Hart, C.L.2    Christie, D.K.3    Upadhyaya, H.P.4
  • 11
    • 0036399623 scopus 로고    scopus 로고
    • Cognitive and subjective dose-response effects of acute oral Delta 9-tetrahydrocannabinol (THC) in infrequent cannabis users
    • Curran H. V., Brignell C., Fletcher S., Middleton P., Henry J. Cognitive and subjective dose-response effects of acute oral Delta 9-tetrahydrocannabinol (THC) in infrequent cannabis users. Psychopharmacology (Berl) 2002; 164: 61-70.
    • (2002) Psychopharmacology (Berl) , vol.164 , pp. 61-70
    • Curran, H.V.1    Brignell, C.2    Fletcher, S.3    Middleton, P.4    Henry, J.5
  • 12
    • 0032586698 scopus 로고    scopus 로고
    • Responses to oral delta9-tetrahydrocannabinol in frequent and infrequent marijuana users
    • Kirk J. M., de Wit H. Responses to oral delta9-tetrahydrocannabinol in frequent and infrequent marijuana users. Pharmacol Biochem Behav 1999; 63: 137-142.
    • (1999) Pharmacol Biochem Behav , vol.63 , pp. 137-142
    • Kirk, J.M.1    de Wit, H.2
  • 13
    • 23944513023 scopus 로고    scopus 로고
    • Assessment of driving capability through the use of clinical and psychomotor tests in relation to blood cannabinoids levels following oral administration of 20mg dronabinol or of a cannabis decoction made with 20 or 60mg Delta9-THC
    • Menetrey A., Augsburger M., Favrat B., Pin M. A., Rothuizen L. E., Appenzeller M. etal. Assessment of driving capability through the use of clinical and psychomotor tests in relation to blood cannabinoids levels following oral administration of 20mg dronabinol or of a cannabis decoction made with 20 or 60mg Delta9-THC. J Anal Toxicol 2005; 29: 327-338.
    • (2005) J Anal Toxicol , vol.29 , pp. 327-338
    • Menetrey, A.1    Augsburger, M.2    Favrat, B.3    Pin, M.A.4    Rothuizen, L.E.5    Appenzeller, M.6
  • 14
    • 0031762435 scopus 로고    scopus 로고
    • Marijuana's impairing effects on driving are moderate when taken alone but severe when combined with alcohol
    • Robbe H. Marijuana's impairing effects on driving are moderate when taken alone but severe when combined with alcohol. Hum Psychopharmacol Clin Exp 1998; 13: S70-78.
    • (1998) Hum Psychopharmacol Clin Exp , vol.13
    • Robbe, H.1
  • 17
    • 0021721450 scopus 로고
    • Driving performance under the influence of drugs: rationale for, and application of, a new test
    • O'Hanlon J. F. Driving performance under the influence of drugs: rationale for, and application of, a new test. Br J Clin Pharmacol 1984; 18: 121S-129.
    • (1984) Br J Clin Pharmacol , vol.18
    • O'Hanlon, J.F.1
  • 18
    • 0002568248 scopus 로고
    • The relationship between drivers' blood alcohol concentration (BAC) and actual driving performance during high speed travel
    • Louwerens J., Gloerich A., de Vries G., Brookhuis K., O'Hanlon J. The relationship between drivers' blood alcohol concentration (BAC) and actual driving performance during high speed travel. Alcohol Drugs Traffic Saf 1987; 86: 183-186.
    • (1987) Alcohol Drugs Traffic Saf , vol.86 , pp. 183-186
    • Louwerens, J.1    de Gloerich, A.2    Vries, G.3    Brookhuis, K.4    O'Hanlon, J.5
  • 19
    • 0019967272 scopus 로고
    • Diazepam impairs lateral position control in highway driving
    • O'Hanlon J. F., Haak T. W., Blaauw G. J., Riemersma J. B. Diazepam impairs lateral position control in highway driving. Science 1982; 217: 79-81.
    • (1982) Science , vol.217 , pp. 79-81
    • O'Hanlon, J.F.1    Haak, T.W.2    Blaauw, G.J.3    Riemersma, J.B.4
  • 20
    • 0037269674 scopus 로고    scopus 로고
    • Antidepressants and driver impairment: empirical evidence from a standard on-the-road test
    • Ramaekers J. G. Antidepressants and driver impairment: empirical evidence from a standard on-the-road test. J Clin Psychiatry 2003; 64: 20-29.
    • (2003) J Clin Psychiatry , vol.64 , pp. 20-29
    • Ramaekers, J.G.1
  • 21
    • 0028401515 scopus 로고
    • Measuring driving performance by car-following in traffic
    • Brookhuis K. A., de Waard D., Mulder B. Measuring driving performance by car-following in traffic. Ergonomics 1994; 37: 427-434.
    • (1994) Ergonomics , vol.37 , pp. 427-434
    • Brookhuis, K.A.1    de Waard, D.2    Mulder, B.3
  • 22
    • 0036166490 scopus 로고    scopus 로고
    • A comparative study of the effects of carbamazepine and the NMDA receptor antagonist remacemide on road tracking and car-following performance in actual traffic
    • Ramaekers J. G., Lamers J., Verhey F., Muntjewerff D., Mobbs E., Sanders N. etal. A comparative study of the effects of carbamazepine and the NMDA receptor antagonist remacemide on road tracking and car-following performance in actual traffic. Psychopharmacology (Berl) 2002; 159: 203-210.
    • (2002) Psychopharmacology (Berl) , vol.159 , pp. 203-210
    • Ramaekers, J.G.1    Lamers, J.2    Verhey, F.3    Muntjewerff, D.4    Mobbs, E.5    Sanders, N.6
  • 23
    • 84866044322 scopus 로고    scopus 로고
    • Validation of the Standardized Field Sobriety Test Battery at BACs Below 0.10. DOT-HS-808-839. Washington, DC: US Department of Transportation, National Highway Traffic Safety Administration
    • Stuster J., Burns M. Validation of the Standardized Field Sobriety Test Battery at BACs Below 0.10. DOT-HS-808-839. Washington, DC: US Department of Transportation, National Highway Traffic Safety Administration; 1998.
    • (1998)
    • Stuster, J.1    Burns, M.2
  • 24
    • 21244501729 scopus 로고    scopus 로고
    • An evaluation of the sensitivity of the Standardised Field Sobriety Tests (SFSTs) to detect impairment due to marijuana intoxication
    • Papafotiou K., Carter J. D., Stough C. An evaluation of the sensitivity of the Standardised Field Sobriety Tests (SFSTs) to detect impairment due to marijuana intoxication. Psychopharmacology (Berl) 2005; 180: 107-114.
    • (2005) Psychopharmacology (Berl) , vol.180 , pp. 107-114
    • Papafotiou, K.1    Carter, J.D.2    Stough, C.3
  • 26
    • 26844513819 scopus 로고    scopus 로고
    • The relationship between performance on the standardised field sobriety tests, driving performance and the level of Delta9-tetrahydrocannabinol (THC) in blood
    • Papafotiou K., Carter J. D., Stough C. The relationship between performance on the standardised field sobriety tests, driving performance and the level of Delta9-tetrahydrocannabinol (THC) in blood. Forensic Sci Int 2005; 155: 172-178.
    • (2005) Forensic Sci Int , vol.155 , pp. 172-178
    • Papafotiou, K.1    Carter, J.D.2    Stough, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.