Apoptotic cell death by the novel natural compound, cinobufotalin

Chemico-Biological Interactions

Volumn 199, Issue 3, 2012, Pages 154-160

  Emam, Heba ^a   Zhao, Qing Li ^a   Furusawa, Yukihiro ^a   Refaat, Alaa ^a   Ahmed, Kanwal ^a   Kadowaki, Makoto ^a   Kondo, Takashi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Apoptosis; Ca2+; Cinobufotalin; Fas; Mitochondria; Phosphatidylserine

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CALCIUM ION; CASPASE 2; CASPASE 3; CASPASE 8; CASPASE 9; CINOBUFOTALIN; CYTOCHROME C; FAS ANTIGEN; NATURAL PRODUCT; PROTEIN BAX; PROTEIN BID; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CANCER CHEMOTHERAPY; CELL STRAIN U937; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; HELA CELL; HUMAN; HUMAN CELL; INCUBATION TIME; INTRACELLULAR SIGNALING; LYMPHOMA; MICROSCOPY; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INDUCTION; UPREGULATION; WESTERN BLOTTING;

AMPHIBIAN VENOMS; ANIMALS; ANTIGENS, CD95; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BUFANOLIDES; CALCIUM; CASPASES; DNA FRAGMENTATION; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HUMANS; MEDICINE, CHINESE TRADITIONAL; MEMBRANE POTENTIAL, MITOCHONDRIAL; METABOLIC NETWORKS AND PATHWAYS; REACTIVE OXYGEN SPECIES; U937 CELLS;

ANURA;

EID: 84866036984     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2012.07.005     Document Type: Article

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