MicroRNA profiling of primary high-grade soft tissue sarcomas

Genes Chromosomes and Cancer

Volumn 51, Issue 11, 2012, Pages 982-996

  Renner, Marcus ^a   Czwan, Esteban ^b   Hartmann, Wolfgang ^c   Penzel, Roland ^a   Brors, Benedikt ^b   Eils, Roland ^b   Wardelmann, Eva ^c   Büttner, Reinhard ^c   Lichter, Peter ^b   Schirmacher, Peter ^a   Mechtersheimer, Gunhild ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 200; MICRORNA 9;

ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; CHROMOSOME 14Q; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; LEIOMYOSARCOMA; MYXOSARCOMA; PRIORITY JOURNAL; SOFT TISSUE SARCOMA; SYNOVIAL SARCOMA;

CELL LINE, TUMOR; CLUSTER ANALYSIS; COMPUTATIONAL BIOLOGY; GENE EXPRESSION PROFILING; GENETIC MARKERS; HUMANS; MICRORNAS; NEOPLASM GRADING; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; SARCOMA;

EID: 84865997917     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.21980     Document Type: Article

References (44)

1. Adamowicz M, Radlwimmer B, Rieker RJ, Mertens D, Schwarzbach M, Schraml P, Benner A, Lichter P, Mechtersheimer G, Joos S. 2006. Frequent amplifications and abundant expression of TRIO, NKD2, and IRX2 in soft tissue sarcomas. Genes Chromosomes Cancer 45: 829-838.
2. Aman P, Ron D, Mandahl N, Fioretos T, Heim S, Arheden K, Willen H, Rydholm A, Mitelman F. 1992. Rearrangement of the transcription factor gene CHOP in myxoid liposarcomas with t(12;16)(q13;p11). Genes Chromosomes Cancer 5: 278-285.
3. Antonescu CR. 2008. Molecular profiling in the diagnosis and treatment of high grade sarcomas. Ultrastruct Pathol 32: 37-42.
4. Benjamini Y, Hochberg Y. 1995. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B (Methodol) 57: 289-300.
5. Birks DK, Barton VN, Donson AM, Handler MH, Vibhakar R, Foreman NK. 2011. Survey of MicroRNA expression in pediatric brain tumors. Pediatr Blood Cancer 56: 211-216.
6. Brabletz S, Brabletz T. 2010. The ZEB/miR-200 feedback loop-A motor of cellular plasticity in development and cancer? EMBO Rep 11: 670-677.
7. Braun CJ, Zhang X, Savelyeva I, Wolff S, Moll UM, Schepeler T, Orntoft TF, Andersen CL, Dobbelstein M. 2008. p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest. Cancer Res 68: 10094-10104.
8. Calin GA, Croce CM. 2006. MicroRNA signatures in human cancers. Nat Rev Cancer 6: 857-866.
9. Carneiro A, Francis P, Bendahl PO, Fernebro J, Akerman M, Fletcher C, Rydholm A, Borg A, Nilbert M. 2009. Indistinguishable genomic profiles and shared prognostic markers in undifferentiated pleomorphic sarcoma and leiomyosarcoma: Different sides of a single coin? Lab Invest 89: 668-675.
10. Chen JF, Mandel EM, Thomson JM, Wu Q, Callis TE, Hammond SM, Conlon FL, Wang DZ. 2006. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet 38: 228-233.
11. Doench JG, Sharp PA. 2004. Specificity of microRNA target selection in translational repression. Genes Dev 18: 504-511.
12. Fletcher CD. 2006. The evolving classification of soft tissue tumours: An update based on the new WHO classification. Histopathology 48: 3-12.
13. Francis P, Namlos HM, Muller C, Eden P, Fernebro J, Berner JM, Bjerkehagen B, Akerman M, Bendahl PO, Isinger A, Rydholm A, Myklebost O, Nilbert M. 2007. Diagnostic and prognostic gene expression signatures in 177 soft tissue sarcomas: Hypoxia-induced transcription profile signifies metastatic potential. Biomed Chromatogr Genomics 8: 73.
14. Fritz B, Schubert F, Wrobel G, Schwaenen C, Wessendorf S, Nessling M, Korz C, Rieker RJ, Montgomery K, Kucherlapati R, Mechtersheimer G, Eils R, Joos S, Lichter P. 2002. Microarray-based copy number and expression profiling in dedifferentiated and pleomorphic liposarcoma. Cancer Res 62: 2993-2998.
15. Greco S, De Simone M, Colussi C, Zaccagnini G, Fasanaro P, Pescatori M, Cardani R, Perbellini R, Isaia E, Sale P, Meola G, Capogrossi MC, Gaetano C, Martelli F. 2009. Common micro-RNA signature in skeletal muscle damage and regeneration induced by Duchenne muscular dystrophy and acute ischemia. FASEB J 23: 3335-3346.
16. Haller F, von Heydebreck A, Zhang JD, Gunawan B, Langer C, Ramadori G, Wiemann S, Sahin O. 2010. Localization- and mutation-dependent microRNA (miRNA) expression signatures in gastrointestinal stromal tumours (GISTs), with a cluster of co-expressed miRNAs located at 14q32.31. J Pathol 220: 71-86.
17. Hisaoka M, Matsuyama A, Nagao Y, Luan L, Kuroda T, Akiyama H, Kondo S, Hashimoto H. 2011. Identification of altered MicroRNA expression patterns in synovial sarcoma. Genes Chromosomes Cancer 50: 137-145.
18. Kawai A, Naito N, Yoshida A, Morimoto Y, Ouchida M, Shimizu K, Beppu Y. 2004. Establishment and characterization of a biphasic synovial sarcoma cell line, SYO-1. Cancer Lett 204: 105-113.
19. Kennell JA, Gerin I, MacDougald OA, Cadigan KM. 2008. The microRNA miR-8 is a conserved negative regulator of Wnt signaling. Proc Natl Acad Sci USA 105: 15417-15422.
20. Korpal M, Kang Y. 2008. The emerging role of miR-200 family of microRNAs in epithelial-mesenchymal transition and cancer metastasis. RNA Biol 5: 115-119.
21. Ling HY, Wen GB, Feng SD, Tuo QH, Ou HS, Yao CH, Zhu BY, Gao ZP, Zhang L, Liao DF. 2011. MicroRNA-375 promotes 3T3-L1 adipocyte differentiation through modulation of extracellular signal-regulated kinase signalling. Clin Exp Pharmacol Physiol 38: 239-246.
22. Liu X, Sempere LF, Galimberti F, Freemantle SJ, Black C, Dragnev KH, Ma Y, Fiering S, Memoli V, Li H, DiRenzo J, Korc M, Cole CN, Bak M, Kauppinen S, Dmitrovsky E. 2009. Uncovering growth-suppressive MicroRNAs in lung cancer. Clin Cancer Res 15: 1177-1183.
23. Liu L, Luo GZ, Yang W, Zhao X, Zheng Q, Lv Z, Li W, Wu HJ, Wang L, Wang XJ, Zhou Q. 2010. Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells. J Biol Chem 285: 19483-19490.
24. Luk JM, Burchard J, Zhang C, Liu AM, Wong KF, Shek FH, Lee NP, Fan ST, Poon RT, Ivanovska I, Philippar U, Cleary MA, Buser CA, Shaw PM, Lee CN, Tenen DG, Dai H, Mao M. 2011. DLK1-DIO3 genomic imprinted MicroRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival. J Biol Chem 286: 30706-30713.
25. Ma L, Young J, Prabhala H, Pan E, Mestdagh P, Muth D, Teruya-Feldstein J, Reinhardt F, Onder TT, Valastyan S, Westermann F, Speleman F, Vandesompele J, Weinberg RA. 2010. miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol 12: 247-256.
26. Nass D, Rosenwald S, Meiri E, Gilad S, Tabibian-Keissar H, Schlosberg A, Kuker H, Sion-Vardy N, Tobar A, Kharenko O, Sitbon E, Lithwick Yanai G, Elyakim E, Cholakh H, Gibori H, Spector Y, Bentwich Z, Barshack I, Rosenfeld N. 2009. MiR-92b and miR-9/9* are specifically expressed in brain primary tumors and can be used to differentiate primary from metastatic brain tumors. Brain Pathol 19: 375-383.
27. Nishio J, Iwasaki H, Ishiguro M, Ohjimi Y, Fujita C, Ikegami H, Ariyoshi A, Naito M, Kaneko Y, Kikuchi M. 2003. Establishment of a novel human dedifferentiated liposarcoma cell line, FU-DDLS-1: Conventional and molecular cytogenetic characterization. Int J Oncol 22: 535-542.
28. Park SM, Gaur AB, Lengyel E, Peter ME. 2008. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev 22: 894-907.
29. Peter ME. 2009. Let-7 and miR-200 microRNAs: Guardians against pluripotency and cancer progression. Cell Cycle 8: 843-852.
30. Romao JM, Jin W, Dodson MV, Hausman GJ, Moore SS, Guan le L. 2011. MicroRNA regulation in mammalian adipogenesis. Exp Biol Med (Maywood) 236: 997-1004.
31. Royo H, Bortolin ML, Seitz H, Cavaille J. 2006. Small non-coding RNAs and genomic imprinting. Cytogenet Genome Res 113: 99-108.
32. Ryan BM, Robles AI, Harris CC. 2010. Genetic variation in microRNA networks: The implications for cancer research. Nat Rev Cancer 10: 389-402.
33. Sarver AL, Li L, Subramanian S. 2010. MicroRNA miR-183 functions as an oncogene by targeting the transcription factor EGR1 and promoting tumor cell migration. Cancer Res 70: 9570-9580.
34. Seitz H, Royo H, Bortolin ML, Lin SP, Ferguson-Smith AC, Cavaille J. 2004. A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain. Genome Res 14: 1741-1748.
35. Song B, Wang Y, Titmus MA, Botchkina G, Formentini A, Kornmann M, Ju J. 2010. Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells. Mol Cancer 9: 96.
36. Subramanian S, Lui WO, Lee CH, Espinosa I, Nielsen TO, Heinrich MC, Corless CL, Fire AZ, van de Rijn M. 2008. MicroRNA expression signature of human sarcomas. Oncogene 27: 2015-2026.
37. Szymanska J, Serra M, Skytting B, Larsson O, Virolainen M, Akerman M, Tarkkanen M, Huuhtanen R, Picci P, Bacchini P, Asko-Seljavaara S, Elomaa I, Knuutila S. 1998. Genetic imbalances in 67 synovial sarcomas evaluated by comparative genomic hybridization. Genes Chromosomes Cancer 23: 213-219.
38. Torella D, Iaconetti C, Catalucci D, Ellison GM, Leone A, Waring CD, Bochicchio A, Vicinanza C, Aquila I, Curcio A, Condorelli G, Indolfi C. 2011. MicroRNA-133 controls vascular smooth muscle cell phenotypic switch in vitro and vascular remodeling in vivo. Circ Res 109: 880-893.
39. Ugras S, Brill E, Jacobsen A, Hafner M, Socci ND, Decarolis PL, Khanin R, O'Connor R, Mihailovic A, Taylor BS, Sheridan R, Gimble JM, Viale A, Crago A, Antonescu CR, Sander C, Tuschl T, Singer S. 2011. Small RNA sequencing and functional characterization reveals MicroRNA-143 tumor suppressor activity in liposarcoma. Cancer Res 71: 5659-5669.
40. Valastyan S, Reinhardt F, Benaich N, Calogrias D, Szasz AM, Wang ZC, Brock JE, Richardson AL, Weinberg RA. 2009. A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell 137: 1032-1046.
41. van de Rijn M, Fletcher JA. 2006. Genetics of soft tissue tumors. Annu Rev Pathol 1: 435-466.
42. Wang W, Peng B, Wang D, Ma X, Jiang D, Zhao J, Yu L. 2011. Human tumor MicroRNA signatures derived from large-scale oligonucleotide microarray datasets. Int J Cancer 129:7: 1624-1634.
43. Wangyu Z, Xiaoguang L, Jianying H, Dongdong C, Yanyan H, Yongkui Z. 2011. Overexpression of members of the microRNA-183 family is a risk factor for lung cancer: A case control study. BMC Cancer 11: 393.
44. Zagars GK, Ballo MT, Pisters PW, Pollock RE, Patel SR, Benjamin RS, Evans HL. 2003. Prognostic factors for patients with localized soft-tissue sarcoma treated with conservation surgery and radiation therapy: An analysis of 1225 patients. Cancer 97: 2530-2543.