The influence of lactose intolerance and other gastro-intestinal tract disorders on L-thyroxine absorption

Endokrynologia Polska

Volumn 63, Issue 4, 2012, Pages 318-323

  Ruchała, Marek ^a   Szczepanek Parulska, Ewelina ^a   Zybek, Ariadna ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Coeliac disease; Hypothyroidism; L thyroxine; Lactose intolerance; Malabsorption

Indexed keywords

LEVOTHYROXINE; LIOTHYRONINE;

ADD ON THERAPY; ATROPHIC GASTRITIS; CELIAC DISEASE; DIARRHEA; DISEASE ASSOCIATION; DRUG ABSORPTION; DRUG DOSE INCREASE; DRUG MEGADOSE; GASTROINTESTINAL DISEASE; GLUTEN FREE DIET; HASHIMOTO DISEASE; HELICOBACTER INFECTION; HUMAN; HYPOTHYROIDISM; INTESTINE RESECTION; LACTOSE INTOLERANCE; POLAND; REVIEW; SIDE EFFECT; THYROIDITIS;

CELIAC DISEASE; DIET, GLUTEN-FREE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; GASTROINTESTINAL DISEASES; HUMANS; HYPOTHYROIDISM; INTESTINAL ABSORPTION; LACTOSE INTOLERANCE; THYROXINE;

EID: 84865975946     PISSN: 0423104X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (49)

1. Ruchala M, Szczepanek E. Hypothyroidism in primary care. Family Medicine & Primary Care Review 2009; 11: 732-740.
2. Benvenga S, Bartolone L, Squadrito S et al. Delayed intestinal absorption of levothyroxine. Thyroid 1995; 5: 249-253.
3. Munoz-Torres M, Varsavsky M, Alonso G. Lactose intolerance revealed by severe resistance to treatment with levothyroxine. Thyroid 2006; 16: 1171-1173. (Pubitemid 44864493)
4. Bach-Huynh TG, Nayak B, Loh J et al. Timing of levothyroxine administration affects serum thyrotropin concentration. J Clin Endocrinol Metab 2009; 94: 3905-3912.
5. Lamson MJ, Pamplin CL, Rolleri RL, Klein I. Quantitation of a substantial reduction in levothyroxine (T4) absorption by food. Thyroid 2004; 14: 876.
6. Wenzel KW, Kirschsieper HE. Aspects of the absorption of oral L-thyroxine in normal man. Metabolism 1977; 26: 1-8. (Pubitemid 8027634)
7. Bolk N, Visser TJ, Kalsbeek A et al. Effects of evening vs morning thyroxine ingestion on serum thyroid hormone profiles in hypothyroid patients. Clin Endocrinol (Oxf) 2007; 66: 43-48. (Pubitemid 44952493)
8. Elliott DP. Effect of levothyroxine administration time on serum TSH in elderly patients. Ann Pharmacother 2001; 35: 529-532. (Pubitemid 32428124)
9. Campbell NR, Hasinoff BB, Stalts H et al. Ferrous sulfate reduces thyroxine efficacy in patients with hypothyroidism. Ann Intern Med 1992; 117: 1010-1013.
10. John-Kalarickal J, Pearlman G, Carlson HE. New medications which decrease levothyroxine absorption. Thyroid 2007; 17: 763-765. (Pubitemid 350194737)
11. Madhava K, Hartley A. Hypothyroidism in thyroid carcinoma follow-up: orlistat may inhibit the absorption of thyroxine. Clin Oncol (R Coll Radiol) 2005; 17: 492.
12. Sachmechi I, Reich DM, Aninyei M et al. Effect of proton pump inhibitors on serum thyroid-stimulating hormone level in euthyroid patients treated with levothyroxine for hypothyroidism. Endocr Pract 2007; 13: 345-349.
13. Sherman SI, Tielens ET, Ladenson PW. Sucralfate causes malabsorption of L-thyroxine. Am J Med 1994; 96: 531-535. (Pubitemid 24184438)
14. Singh N, Singh PN, Hershman JM. Effect of calcium carbonate on the absorption of levothyroxine. JAMA 2000; 283: 2822-2825. (Pubitemid 30387827)
15. Siraj ES, Gupta MK, Reddy SS. Raloxifene causing malabsorption of levothyroxine. Arch Intern Med 2003; 163: 1367-1370. (Pubitemid 36676204)
16. Berg JA, Mayor GH. A study in normal human volunteers to compare the rate and extent of levothyroxine absorption from Synthroid and Levoxine. J Clin Pharmacol 1992; 32: 1135-1140. (Pubitemid 23033668)
17. Blakesley V, Awni W, Locke C et al. Are bioequivalence studies of levothyroxine sodium formulations in euthyroid volunteers reliable? Thyroid 2004; 14: 191-200. (Pubitemid 38452191)
18. Hennessey JV. Levothyroxine dosage and the limitations of current bioequivalence standards. Nat Clin Pract Endocrinol Metab 2006; 2: 474-475. (Pubitemid 44353283)
19. Nowak N, Łoza B. Lactose intolerance in psychiatric practice. Rev Clin Neuropsychiatry 2010; 2: 137-176.
20. Lilja JJ, Laitinen K, Neuvonen PJ. Effects of grapefruit juice on the absorption of levothyroxine. Br J Clin Pharmacol 2005; 60: 337-341. (Pubitemid 41224144)
21. Deiana L, Marini S, Mariotti S. Ingestion of large amounts of papaya fruit and impaired effectiveness of levothyroxine therapy. Endocr Pract 2012; 18: 98-100.
22. Liel Y, Harman-Boehm I, Shany S. Evidence for a clinically important adverse effect of fiber-enriched diet on the bioavailability of levothyroxine in adult hypothyroid patients. J Clin Endocrinol Metab 1996; 81: 857-859. (Pubitemid 26055713)
23. Bell DS, Ovalle F. Use of soy protein supplement and resultant need for increased dose of levothyroxine. Endocr Pract 2001; 7: 193-194. (Pubitemid 32514876)
24. Benvenga S, Bartolone L, Pappalardo MA et al. Altered intestinal absorption of L-thyroxine caused by coffee. Thyroid 2008; 18: 293-301. (Pubitemid 351415797)
25. Hutyra T, Iwańczak B. Lactose intolerance: pathophysiology, clinical symptoms, diagnosis and treatment. Pol Merk Lek 2009; 26: 148.
26. Swora E, Grzymislawski M. Selected aspects of diagnostics and treatment of some diseases causing malabsorption syndrome. Gastroenterol Pol 2012; 19: 21-24.
27. Eadala P, Waud JP, Matthews SB i wsp. Quantifying the 'hidden' lactose in drugs used for the treatment of gastrointestinal conditions. Aliment Pharmacol Ther 2009; 29: 677-687.
28. d'Esteve-Bonetti L, Bennet AP, Malet D et al. Gluten-induced enteropathy (coeliac disease) revealed by resistance to treatment with levothyroxine and alfacalcidol in a sixty-eight-year-old patient: a case report. Thyroid 2002; 12: 633-636. (Pubitemid 34815522)
29. Silva CM, Souza MV. [Autoimmune hypothyroidism nonresponsive to high doses of levothyroxine and severe hypocalcemia]. Arq Bras Endocrinol Metabol 2005; 49: 599-603.
30. Caputo M, Brizzolara R, Schiavo M et al. Occurrence of overt celiac disease in the elderly following total thyroidectomy. J Endocrinol Invest 2006; 29: 831-833. (Pubitemid 44869429)
31. McDermott JH, Coss A, Walsh CH. Celiac disease presenting as resistant hypothyroidism. Thyroid 2005; 15: 386-388. (Pubitemid 40677414)
32. Khandwala HM, Chibbar R, Bedi A. Celiac disease occurring in a patient with hypoparathyroidism and autoimmune thyroid disease. South Med J 2006; 99: 290-292.
33. Jiskra J, Limanova Z, Vanickova Z et al. IgA and IgG antigliadin, IgA anti-tissue transglutaminase and antiendomysial antibodies in patients with autoimmune thyroid diseases and their relationship to thyroidal replacement therapy. Physiol Res 2003; 52: 79-88. (Pubitemid 36356264)
34. Virili C, Bassotti G, Santaguida MG et al. Atypical celiac disease as cause of increased need for thyroxine: a systematic study. J Clin Endocrinol Metab 2012; 97: E419-E422.
35. Ruchala M, Kosowicz J, Baumann-Antczak A et al. The prevalence of autoantibodies to: myosin, troponin, tropomyosin and myoglobin in patients with circulating triiodothyronine and thyroxine autoantibodies (THAA). Neuro Endocrinol Lett 2007; 28: 259-266. (Pubitemid 47045769)
36. Hadithi M, de Boer H, Meijer JW et al. Coeliac disease in Dutch patients with Hashimoto's thyroiditis and vice versa. World J Gastroenterol 2007; 13: 1715-1722. (Pubitemid 46711344)
37. Collins D, Wilcox R, Nathan M et al. Celiac disease and hypothyroidism. Am J Med 2012; 125: 278-282.
38. Annibale B, Negrini R, Caruana P et al. Two-thirds of atrophic body gastritis patients have evidence of Helicobacter pylori infection. Helicobacter 2001; 6: 225-233. (Pubitemid 32843606)
39. Centanni M, Gargano L, Canettieri G et al. Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis. N Engl J Med 2006; 354: 1787-1795.
40. Bugdaci MS, Zuhur SS, Sokmen M et al. The role of Helicobacter pylori in patients with hypothyroidism in whom could not be achieved normal thyrotropin levels despite treatment with high doses of thyroxine. Helicobacter 2011; 16: 124-130.
41. Paśnik K. Chirurgiczne leczenie otyłości. Gastroenterol Pol 2009; 16: 135-139.
42. Padwal R, Brocks D, Sharma AM. A systematic review of drug absorption following bariatric surgery and its theoretical implications. Obes Rev 2010; 11: 41-50.
43. Stone E, Leiter LA, Lambert JR et al. L-thyroxine absorption in patients with short bowel. J Clin Endocrinol Metab 1984; 59: 139-141. (Pubitemid 14087539)
44. Rubio IG, Galrao AL, Santo MA et al. Levothyroxine absorption in morbidly obese patients before and after Roux-En-Y gastric bypass (RYGB) surgery. Obes Surg 2012; 22: 253-258.
45. Radaeli Rde F, Diehl LA. Increased levothyroxine requirement in a woman with previously well-controlled hypothyroidism and intestinal giardiasis. Arq Bras Endocrinol Metabol 2011; 55: 81-84.
46. Seppel T, Rose F, Schlaghecke R. Chronic intestinal giardiasis with isolated levothyroxine malabsorption as reason for severe hypothyroidism - implications for localization of thyroid hormone absorption in the gut. Exp Clin Endocrinol Diabetes 1996; 104: 180-182. (Pubitemid 26130398)
47. Liwanpo L, Hershman JM. Conditions and drugs interfering with thyroxine absorption. Best Pract Res Clin Endocrinol Metab 2009; 23: 781-792.
48. Srinivas V, Oyibo SO. Levothyroxine pseudomalabsorption and thyroxine absorption testing with use of high-dose levothyroxine: case report and discussion. Endocr Pract 2010; 16: 1012-1015.
49. Mussig K, Morike K, Klein R i wsp. [Hypothyroidism due to pseudo-malabsorption of levothyroxine - Case 12/2009]. Dtsch Med Wochenschr 2009; 134: 2514.