Are Bioequivalence Studies of Levothyroxine Sodium Formulations in Euthyroid Volunteers Reliable?

Thyroid

Volumn 14, Issue 3, 2004, Pages 191-200

  Blakesley, Vicky ^a   Awni, Walid ^a   Locke, Charles ^a   Ludden, Thomas ^b   Granneman, G Richard ^a   Braverman, Lewis E ^c  

^a ABBOTT LABORATORIES   (United States)

^b GloboMax LLC   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEVOTHYROXINE SODIUM; THYROXINE;

ACCURACY; ADULT; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; BIOLOGICAL MONITORING; CALCULATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG FORMULATION; DRUG SAFETY; EUTHYROIDISM; FEMALE; FOOD AND DRUG ADMINISTRATION; HUMAN; HUMAN EXPERIMENT; HYPERTHYROIDISM; HYPOTHYROIDISM; IATROGENIC DISEASE; MALE; MATHEMATICAL ANALYSIS; METHODOLOGY; NORMAL HUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RISK; TABLET FORMULATION; THYROXINE BLOOD LEVEL;

ADULT; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GUIDELINES; HUMANS; MALE; MIDDLE AGED; MODELS, STATISTICAL; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; THERAPEUTIC EQUIVALENCY; THYROXINE; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 1842429851     PISSN: 10507256     EISSN: None     Source Type: Journal    
DOI: 10.1089/105072504773297867     Document Type: Article

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