Pharmacological and pharmacokinetic studies of anti-diabetic tropolonato-Zn(II) complexes with Zn(S2O2) coordination mode

Chemical and Pharmaceutical Bulletin

Volumn 60, Issue 9, 2012, Pages 1096-1104

  Murakami, Hiroki ^a   Yasui, Hiroyuki ^a   Yoshikawa, Yutaka ^a  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Anti diabetic effect; Inorganic medicine; Structure activity relationship; Tropolone derivative; Zn(II) complex

Indexed keywords

ADRENALIN; DI(2 MERCAPTOTHIOTROPOLONATO)ZINC; DI(2 MERCAPTOTROPOLONATO)ZINC; DI(HINOKITIOLATO)ZINC; DI(TROPOLONATO)ZINC; FATTY ACID; GLUCOSE; UNCLASSIFIED DRUG; ZINC COMPLEX; ZINC DISULFUR DIOXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; FATTY ACID METABOLISM; GLUCOSE TRANSPORT; IN VITRO STUDY; IN VIVO STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; RAT;

ANIMALS; BLOOD GLUCOSE; COORDINATION COMPLEXES; DIABETES MELLITUS, TYPE 2; GLUCOSE TOLERANCE TEST; HYPOGLYCEMIC AGENTS; INSULIN; MALE; MICE; RATS; RATS, WISTAR; ZINC;

EID: 84865960633     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.c12-00078     Document Type: Article

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