Increased expression of tryptophan-5-hydroxylase 1, but not 2, in brainstem as a result of intrauterine malnutrition

International Journal of Developmental Neuroscience

Volumn 30, Issue 6, 2012, Pages 445-450

  Manjarrez Gutiérrez, Gabriel ^a,b   Martínez Radilla, Karina ^a   Boyzo Montes de Oca, Alfonso ^c   Orozco Suárez, Sandra ^b   Hernández Rodríguez, Jorge ^c  

^a HOSPITAL DE CARDIOLOGÍA   (Mexico)

^b HOSPITAL DE ESPECIALIDADES   (Mexico)

^c DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Intrauterine malnutrition; Serotonin; Tryptophan 5 hydroxylase

Indexed keywords

SEROTONIN; TRYPTOPHAN; TRYPTOPHAN 5 HYDROXYLASE 1; TRYPTOPHAN HYDROXYLASE; TRYPTOPHAN HYDROXYLASE 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; BRAIN METABOLISM; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; ENZYME ANALYSIS; FETAL MALNUTRITION; FETUS; IMMUNOCYTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; RAT; SEROTONIN METABOLISM; WESTERN BLOTTING;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; BODY WEIGHT; BRAIN STEM; DISEASE MODELS, ANIMAL; FEMALE; FETAL NUTRITION DISORDERS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MALE; PREGNANCY; RATS; RATS, WISTAR; SEROTONIN; TRYPTOPHAN HYDROXYLASE;

EID: 84865864615     PISSN: 07365748     EISSN: 1873474X     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2012.07.001     Document Type: Article

References (37)

1. Abumaria N., Rygula R., Havemann-Reinecke U., Rüther E., Bodemer W., Roos C., Flügge G. Identification of genes regulated by chronic social stress in the rat dorsal raphe nucleus. Cellular and Molecular Neurobiology 2006, 26:145-162.
2. Abumaria N., Rygula R., Hiemke C., Fuchs E., Havemann-Reinecke U., Rüther E., Flügge G. Effect of chronic citalopram on serotonin-related and stress-regulated genes in the dorsal raphe nucleus of the rat. European Neuropsychopharmacology 2007, 17:417-429.
3. Abumaria N., Riic A., Anacker Ch., Fuchs E., Flügge G. Stress upregulates TPH1 but not TPH2 mRNA in the rat dorsal raphe nucleus: identification of two TPH2 mRNA splice variants. Cellular and Molecular Neurobiology 2008, 28:331-342.
4. Almeida S.S., Tonkiss J., Galler J.R. Malnutrition and reactivity to drugs acting in the central nervous system. Neuroscience and Biobehavioral Reviews 1996, 20:389-402.
5. Azmitia E.C., McEwen B.S. Adrenocortical influence on rat brain tryptophan hydroxylase activity. Brain Research 1974, 78:291-302.
6. Boadle-Biber M.C., Corley K.C., Graves L., Phan T.H., Rosecrans J. Increase in the activity of tryptophan hydroxylase from cortex and midbrain of male Fischer 344 rats in response to acute or repeated sound stress. Brain Research 1989, 482:306-316.
7. Boadle-Biber M. Regulation of serotonin synthesis. Progress in Biophysics and Molecular Biology 1993, 60:1-15.
8. Chaouloff F., Berton O., Mormede P. Serotonin and stress. Neuropsychopharmacology 1999, 21:28S-32S.
9. Diaz M.A., Chagoya G.G., Hernandez R.J. Modificación por desnutrición ontogénica de la neurotransmision serotoninergica cerebral y de la conducta relacionada. Boletin Medico del Hospital Infantil de Mexico 1993, 60:17-26.
10. Fitzpatrick P.F. The aromatic amino acid hydroxylase. Advances in Enzymology and Related Areas of Molecular Biology 2000, 74:235-294.
11. Gluckman P.D., Hanson M.A. Living with the past: evolution, development and patterns of disease. Science 2004, 305:1733-1736.
12. Grahame-Smith D.G. Tryptophan hydroxylation in brain. Biochemical and Biophysical Research Communications 1964, 16:586-592.
13. Hale C.N., Barker D.J. The thrifty phenotype hypothesis. British Medical Bulletin 2004, 60:5-20.
14. Hernández R.J., Manjarrez G.G., Chagoya G.G. Newborn humans and rats malnourished in utero: free plasma l-tryptophan, neutral amino acids and brain serotonin synthesis. Brain Research 1989, 488:1-13.
15. Hufton S.E., Jennings I.G., Cotton R.G.H. Structure and function of the aromatic aminoacids hydroxylase. Biochemical Journal 1995, 311:353-366.
16. Jequier E., Robinson D.S., Lovenberg W., Sjoerdsma A. Further studies on tryptophan hydroxylase in rat brainstem and beef pineal. Biochemical Pharmacology 1969, 18:1071-1081.
17. Johansen P.A., Jennings I., Cotton R.G.H., Kuhn D.M. Tryptophan hydroxylase is phosphorylated by protein kinase A. Journal of Neurochemistry 1995, 65:882-887.
18. Johansen P.A., Jennings I., Cotton R.G.H., Kuhn D.M. Phosphorylation and activation of tryptophan hydroxylase by exogenous protein kinase A. Journal of Neurochemistry 1996, 66:817-823.
19. Kaufman S. Aromatic amino acid hydroxylases. Biochemical Society Transactions 1985, 13:433-437.
20. Lopes de Souza S., Orozco-Solis R., Grit I., Manhaes de Castro R., Bolaños J.F. Perinatal protein restriction reduces the inhibitory action of serotonin on food intake. European Journal of Neuroscience 2008, 27:1400-1408.
21. Manjarrez G.G., Hernández R.J., Chagoya G.G. Perinatal brain serotonin metabolism in rats malnourished in utero. Biology of the Neonate 1988, 54:232-240.
22. Manjarrez G.G., Chagoya G.G., Hernández R.J. Early nutritional changes modify the kinetics and phosphorylation capacity of tryptophan-5-hydroxylase. International Journal of Developmental Neuroscience 1994, 12:695-702.
23. Manjarrez G.G., Magdaleno V.M., Chagoya G.G., Hernández R.J. Nutritional recovery does not reverse the activation of brain serotonin synthesis in the ontogenetically malnourished rat. International Journal of Developmental Neuroscience 1996, 14:641-648.
24. Manjarrez G., Contreras J.L., Chagoya G., Hernández R.J. Free tryptophan as indicator of brain serotonin synthesis in infants. Pediatric Neurology 1998, 18:57-62.
25. Manjarrez G.G., Herrera M.R., González R.M., Hernández Z.E., Manuel A.L., Hernández R.J. Long-term consequences of early undernourishment on the activation of brain serotonin synthesis in the rat: effect of nutritional recovery during the period of nursing. Nutritional Neuroscience 1999, 2:57-67.
26. Manjarrez G., Cisneros I., Herrera R., Vazquez F., Robles A., Hernandez J. Prenatal impairment of brain serotonergic transmission in infants. Journal of Pediatrics 2005, 147:592-596.
27. Manjarrez G.G., Gonzalez R.M., Boyzo M.O.A., Hernandez R.J. Dihydropteridine reductase activity in the brainstem of intrauterine growth-restricted rats. International Journal of Developmental Neuroscience 2010, 28:621-634.
28. Moran G.R., Daubner S.C., Fitzpatrick P.F. Expression and characterization of the catalytic core of tryptophan hydroxylase. Journal of Biological Chemistry 1998, 273:12259-12260.
29. Morgane P.J., Mokler D.J., Galler J.R. Effect of prenatal protein malnutrition on the hippocampal formation. Neuroscience and Biobehavioral Reviews 2002, 26:471-483.
30. Naish J.S., Boenisch A.J., Farmilio U., Stead R.H. Handbook of Immunochemical Staining Methods 1989, Dako, Carpinteria, CA.
31. Nakamura K., Sugawara Y., Sawabe K., Ohashi A., Tsurui H., Xiu Y., Ohtsuji M., Lin Q.S., Nishimura H., Hasegawa H., Hirose S. Late developmental stage-specific role of tryptophan hydroxylase 1 in brain serotonin levels. Journal of Neuroscience 2006, 26:530-534.
32. Nakamura K., Hasegawa H. Development role of tryptophan hydroxylase in the nervous system. Molecular Neurobiology 2007, 35:45-53.
33. Neckers L., Biggio G., Moja E., Meek J. Modulation of brain tryptophan hydroxylase activity by brain tryptophan content. Journal of Pharmacology and Experimental Therapeutics 1971, 177:475-480.
34. Peat M.A., Gibb J.W. High-performance liquid chromatography determination of indoleamines, dopamine, and norepinephrine in rat brain with fluorometric detection. Analytical Biochemistry 1983, 128:275-280.
35. Veenstra V.W.J., Cook E.H. Knockout mouse points to second form of tryptophan hydroxylase. Molecular Interventions 2003, 3:72-75.
36. Walther D.J. Synthesis of serotonin by second tryptophan hydroxylase isoform. Science 2003, 299:76.
37. Walther D.J., Bader M. A unique central tryptophan hydroxylase isoform. Biochemical Pharmacology 2003, 66:1673-1680.