메뉴 건너뛰기




Volumn 107, Issue 6, 2012, Pages 961-966

Neoadjuvant bevacizumab persistently inactivates VEGF at the time of surgery despite preoperative cessation

Author keywords

bevacizumab; metastasised colorectal cancer; neoadjuvant therapy; VEGF; wound healing

Indexed keywords

BEVACIZUMAB; CAPECITABINE; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; OXALIPLATIN; VASCULOTROPIN;

EID: 84865863548     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2012.342     Document Type: Article
Times cited : (23)

References (42)
  • 1
    • 0038600610 scopus 로고    scopus 로고
    • Chemotherapy and surgery: New perspectives on the treatment of unresectable liver metastases
    • Adam R (2003) Chemotherapy and surgery: new perspectives on the treatment of unresectable liver metastases. Ann Oncol 14(Suppl 2): ii13-ii16
    • (2003) Ann Oncol , vol.14 , Issue.SUPPL. 2
    • Adam, R.1
  • 2
    • 47949099628 scopus 로고    scopus 로고
    • Modes of resistance to anti-angiogenic therapy
    • Bergers G, Hanahan D (2008) Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer 8: 592-603
    • (2008) Nat Rev Cancer , vol.8 , pp. 592-603
    • Bergers, G.1    Hanahan, D.2
  • 4
    • 42249115327 scopus 로고    scopus 로고
    • Neoadjuvant treatment of colorectal cancer with bevacizumab: The perioperative angiogenic balance is sensitive to systemic thrombospondin-1 levels
    • Brostjan C, Gebhardt K, Gruenberger B, Steinrueck V, Zommer H, Freudenthaler H, Roka S, Gruenberger T (2008) Neoadjuvant treatment of colorectal cancer with bevacizumab: the perioperative angiogenic balance is sensitive to systemic thrombospondin-1 levels. Clin Cancer Res 14: 2065-2074
    • (2008) Clin Cancer Res , vol.14 , pp. 2065-2074
    • Brostjan, C.1    Gebhardt, K.2    Gruenberger, B.3    Steinrueck, V.4    Zommer, H.5    Freudenthaler, H.6    Roka, S.7    Gruenberger, T.8
  • 5
    • 26644471951 scopus 로고    scopus 로고
    • Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
    • Casanovas O, Hicklin DJ, Bergers G, Hanahan D (2005) Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors. Cancer Cell 8: 299-309
    • (2005) Cancer Cell , vol.8 , pp. 299-309
    • Casanovas, O.1    Hicklin, D.J.2    Bergers, G.3    Hanahan, D.4
  • 7
    • 24644454338 scopus 로고    scopus 로고
    • Surgical resection after downsizing of colorectal liver metastasis in the era of bevacizumab
    • Ellis LM, Curley SA, Grothey A (2005) Surgical resection after downsizing of colorectal liver metastasis in the era of bevacizumab. J Clin Oncol 23: 4853-4855
    • (2005) J Clin Oncol , vol.23 , pp. 4853-4855
    • Ellis, L.M.1    Curley, S.A.2    Grothey, A.3
  • 8
    • 72249119811 scopus 로고    scopus 로고
    • VEGF-A: A critical regulator of blood vessel growth
    • Ferrara N (2009) VEGF-A: a critical regulator of blood vessel growth. Eur Cytokine Netw 20: 158-163
    • (2009) Eur Cytokine Netw , vol.20 , pp. 158-163
    • Ferrara, N.1
  • 9
    • 0026639806 scopus 로고
    • Angiogenesis
    • Folkman J, Shing Y (1992) Angiogenesis. J Biol Chem 267: 10931-10934
    • (1992) J Biol Chem , vol.267 , pp. 10931-10934
    • Folkman, J.1    Shing, Y.2
  • 10
    • 0033504042 scopus 로고    scopus 로고
    • Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: Analysis of 1001 consecutive cases
    • discussion 318-321
    • Fong Y, Fortner J, Sun RL, Brennan MF, Blumgart LH (1999) Clinical score for predicting recurrence after hepatic resection for metastatic colorectal cancer: analysis of 1001 consecutive cases. Ann Surg 230: 309-318; discussion 318-321
    • (1999) Ann Surg , vol.230 , pp. 309318
    • Fong, Y.1    Fortner, J.2    Sun, R.L.3    Brennan, M.F.4    Blumgart, L.H.5
  • 11
    • 77952994052 scopus 로고    scopus 로고
    • Metastatic colorectal cancer: From improved survival to potential cure
    • Gallagher DJ, Kemeny N (2010) Metastatic colorectal cancer: from improved survival to potential cure. Oncology 78: 237-248
    • (2010) Oncology , vol.78 , pp. 237-248
    • Gallagher, D.J.1    Kemeny, N.2
  • 12
    • 34248173883 scopus 로고    scopus 로고
    • Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200
    • Giantonio BJ, Catalano PJ, Meropol NJ, O'Dwyer PJ, Mitchell EP, Alberts SR, Schwartz MA, Benson 3rd AB (2007) Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 25: 1539-1544
    • (2007) J Clin Oncol , vol.25 , pp. 1539-1544
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3    O'Dwyer, P.J.4    Mitchell, E.P.5    Alberts, S.R.6    Schwartz, M.A.7    Benson Iii., A.B.8
  • 13
    • 42949130734 scopus 로고    scopus 로고
    • Bevacizumab, capecitabine, and oxaliplatin as neoadjuvant therapy for patients with potentially curable metastatic colorectal cancer
    • Gruenberger B, Tamandl D, Schueller J, Scheithauer W, Zielinski C, Herbst F, Gruenberger T (2008) Bevacizumab, capecitabine, and oxaliplatin as neoadjuvant therapy for patients with potentially curable metastatic colorectal cancer. J Clin Oncol 26: 1830-1835
    • (2008) J Clin Oncol , vol.26 , pp. 1830-1835
    • Gruenberger, B.1    Tamandl, D.2    Schueller, J.3    Scheithauer, W.4    Zielinski, C.5    Herbst, F.6    Gruenberger, T.7
  • 14
    • 33744988380 scopus 로고    scopus 로고
    • Neoadjuvant therapy with bevacizumab
    • author reply 2593-2594
    • Gruenberger T, Gruenberger B, Scheithauer W (2006) Neoadjuvant therapy with bevacizumab. J Clin Oncol 24: 2592-2593; author reply 2593-2594
    • (2006) J Clin Oncol , vol.24 , pp. 2592-2593
    • Gruenberger, T.1    Gruenberger, B.2    Scheithauer, W.3
  • 16
    • 80051669505 scopus 로고    scopus 로고
    • Review: Incidence and clinical significance of Bevacizumab-related non-surgical and surgical serious adverse events in metastatic colorectal cancer
    • Hompes D, Ruers T (2011) Review: Incidence and clinical significance of Bevacizumab-related non-surgical and surgical serious adverse events in metastatic colorectal cancer. Eur J Surg Oncol 37: 737-746
    • (2011) Eur J Surg Oncol , vol.37 , pp. 737-746
    • Hompes, D.1    Ruers, T.2
  • 20
    • 20544471876 scopus 로고    scopus 로고
    • Combined analysis of efficacy: The addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer
    • Kabbinavar FF, Hambleton J, Mass RD, Hurwitz HI, Bergsland E, Sarkar S (2005) Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer. J Clin Oncol 23: 3706-3712
    • (2005) J Clin Oncol , vol.23 , pp. 3706-3712
    • Kabbinavar, F.F.1    Hambleton, J.2    Mass, R.D.3    Hurwitz, H.I.4    Bergsland, E.5    Sarkar, S.6
  • 22
    • 34548242252 scopus 로고    scopus 로고
    • Presurgical chemotherapy in patients being considered for liver resection
    • Kemeny N (2007) Presurgical chemotherapy in patients being considered for liver resection. Oncologist 12: 825-839
    • (2007) Oncologist , vol.12 , pp. 825-839
    • Kemeny, N.1
  • 23
    • 55949084563 scopus 로고    scopus 로고
    • Preoperative bevacizumab does not significantly increase postoperative complication rates in patients undergoing hepatic surgery for colorectal cancer liver metastases
    • Kesmodel SB, Ellis LM, Lin E, Chang GJ, Abdalla EK, Kopetz S, Vauthey JN, Rodriguez-Bigas MA, Curley SA, Feig BW (2008) Preoperative bevacizumab does not significantly increase postoperative complication rates in patients undergoing hepatic surgery for colorectal cancer liver metastases. J Clin Oncol 26: 5254-5260
    • (2008) J Clin Oncol , vol.26 , pp. 5254-5260
    • Kesmodel, S.B.1    Ellis, L.M.2    Lin, E.3    Chang, G.J.4    Abdalla, E.K.5    Kopetz, S.6    Vauthey, J.N.7    Rodriguez-Bigas, M.A.8    Curley, S.A.9    Feig, B.W.10
  • 24
    • 29144510498 scopus 로고    scopus 로고
    • The effects of ZD6474, an inhibitor of VEGF signaling, on cutaneous wound healing in mice
    • Ko J, Ross J, Awad H, Hurwitz H, Klitzman B (2005) The effects of ZD6474, an inhibitor of VEGF signaling, on cutaneous wound healing in mice. J Surg Res 129: 251-259
    • (2005) J Surg Res , vol.129 , pp. 251-259
    • Ko, J.1    Ross, J.2    Awad, H.3    Hurwitz, H.4    Klitzman, B.5
  • 28
    • 0031779927 scopus 로고    scopus 로고
    • Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing
    • Nissen NN, Polverini PJ, Koch AE, Volin MV, Gamelli RL, DiPietro LA (1998) Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing. Am J Pathol 152: 1445-1452
    • (1998) Am J Pathol , vol.152 , pp. 1445-1452
    • Nissen, N.N.1    Polverini, P.J.2    Koch, A.E.3    Volin, M.V.4    Gamelli, R.L.5    Dipietro, L.A.6
  • 29
    • 70349690209 scopus 로고    scopus 로고
    • Surgery with curative-intent in patients treated with first-line chemotherapy plus bevacizumab for metastatic colorectal cancer First BEAT and the randomised phase-III NO16966 trial
    • Okines A, Puerto OD, Cunningham D, Chau I, Van Cutsem E, Saltz L, Cassidy J (2009) Surgery with curative-intent in patients treated with first-line chemotherapy plus bevacizumab for metastatic colorectal cancer First BEAT and the randomised phase-III NO16966 trial. Br J Cancer 101: 1033-1038
    • (2009) Br J Cancer , vol.101 , pp. 1033-1038
    • Okines, A.1    Puerto, O.D.2    Cunningham, D.3    Chau, I.4    Van Cutsem, E.5    Saltz, L.6    Cassidy, J.7
  • 30
    • 37249002806 scopus 로고    scopus 로고
    • Addition of bevacizumab to irinotecan-and oxaliplatin-based preoperative chemotherapy regimens does not increase morbidity after resection of colorectal liver metastases
    • Reddy SK, Morse MA, Hurwitz HI, Bendell JC, Gan TJ, Hill SE, Clary BM (2008) Addition of bevacizumab to irinotecan-and oxaliplatin-based preoperative chemotherapy regimens does not increase morbidity after resection of colorectal liver metastases. J Am Coll Surg 206: 96-106
    • (2008) J Am Coll Surg , vol.206 , pp. 96-106
    • Reddy, S.K.1    Morse, M.A.2    Hurwitz, H.I.3    Bendell, J.C.4    Gan, T.J.5    Hill, S.E.6    Clary, B.M.7
  • 31
    • 0035018909 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and liver regeneration
    • Reynaert H, Chavez M, Geerts A (2001) Vascular endothelial growth factor and liver regeneration. J Hepatol 34: 759-761
    • (2001) J Hepatol , vol.34 , pp. 759-761
    • Reynaert, H.1    Chavez, M.2    Geerts, A.3
  • 32
    • 2442636729 scopus 로고    scopus 로고
    • Loss of vascular endothelial growth factor a activity in murine epidermal keratinocytes delays wound healing and inhibits tumor formation
    • Rossiter H, Barresi C, Pammer J, Rendl M, Haigh J, Wagner EF, Tschachler E (2004) Loss of vascular endothelial growth factor a activity in murine epidermal keratinocytes delays wound healing and inhibits tumor formation. Cancer Res 64: 3508-3516
    • (2004) Cancer Res , vol.64 , pp. 3508-3516
    • Rossiter, H.1    Barresi, C.2    Pammer, J.3    Rendl, M.4    Haigh, J.5    Wagner, E.F.6    Tschachler, E.7
  • 34
    • 33645731843 scopus 로고    scopus 로고
    • Surgical resection of hepatic metastases from colorectal cancer: A systematic review of published studies
    • Simmonds PC, Primrose JN, Colquitt JL, Garden OJ, Poston GJ, Rees M (2006) Surgical resection of hepatic metastases from colorectal cancer: a systematic review of published studies. Br J Cancer 94: 982-999
    • (2006) Br J Cancer , vol.94 , pp. 982-999
    • Simmonds, P.C.1    Primrose, J.N.2    Colquitt, J.L.3    Garden, O.J.4    Poston, G.J.5    Rees, M.6
  • 38
    • 77954089195 scopus 로고    scopus 로고
    • Liver resection remains a safe procedure after neoadjuvant chemotherapy including bevacizumab: A case-controlled study
    • Tamandl D, Gruenberger B, Klinger M, Herberger B, Kaczirek K, Fleischmann E, Gruenberger T (2010) Liver resection remains a safe procedure after neoadjuvant chemotherapy including bevacizumab: a case-controlled study. Ann Surg 252: 124-130
    • (2010) Ann Surg , vol.252 , pp. 124-130
    • Tamandl, D.1    Gruenberger, B.2    Klinger, M.3    Herberger, B.4    Kaczirek, K.5    Fleischmann, E.6    Gruenberger, T.7
  • 40
    • 66549124650 scopus 로고    scopus 로고
    • Advanced colorectal cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up
    • Van Cutsem E, Oliveira J (2009) Advanced colorectal cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol 20(Suppl 4): 61-63
    • (2009) Ann Oncol , vol.20 , Issue.SUPPL. 4 , pp. 61-63
    • Van Cutsem, E.1    Oliveira, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.