Direct response to proton beam linear energy transfer (LET) in a novel polymer gel dosimeter formulation

Technology in Cancer Research and Treatment

Volumn 11, Issue 5, 2012, Pages 441-445

  Lopatiuk Tirpak, O ^a   Su, Z ^b   Li, Z ^b   Zeidan, O A ^c   Meeks, S L ^a   Maryanski, M J ^d  

^a M D ANDERSON CANCER CENTER ORLANDO   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c ProCure Proton Therapy Center   (United States)

^d MGS Research Inc   (United States)

Author keywords

Linear energy transfer; Polymer gel dosimetry; Proton therapy

Indexed keywords

POLYMER;

ARTICLE; CALCULATION; COMPUTED TOMOGRAPHY SCANNER; DOSIMETER; EVALUATION; GEL; LINEAR ENERGY TRANSFER; MATHEMATICAL COMPUTING; OPTICAL DENSITY; POLYMERIZATION; PROTON RADIATION; PROTON THERAPY; RADIATION DOSE DISTRIBUTION;

EID: 84865858664     PISSN: 15330346     EISSN: None     Source Type: Journal    
DOI: 10.7785/tcrt.2012.500263     Document Type: Article

References (19)

1. Paganetti, H., Niemierko, A., Ancukiewicz, M., Gerweck, L. E., Goitein, M., Loeffler, J. S., Suit, H. D. Relative biological effectiveness (RBE) values for proton beam therapy. Int J Radiat Oncol Biol Phys 53, 407-421 (2002).
2. Paganetti, H., Olko, P., Kobus, H., Becker, R., Schmitz, T., Waligorski, M. P. R., Filges, D., Müller-Gärtner, H.-W. Calculation of relative biological effectiveness for proton beams using biological weighting functions. Int J Radiat Oncol Biol Phys 37, 719-729 (1997).
3. Kohno, T., Kiyota, T., Matsufuji, N., Futami, Y., Kanai, T. Response of multiwire proportional counter for energy loss measurement. Nucl Instrum Meth A 450, 456-466 (2000).
4. Borak, T. B., Doke, T., Fuse, T., Guetersloh, S., Heilbronn, L., Hara, K., Moyers, M., Suzuki, S., Taddei, P., Terasawa, K., Zeitlin, C. J. Comparisons of LET distributions for protons with energies between 50 and 200 MeV determined using a spherical tissue-equivalent proportional counter (TEPC) and a position-sensitive silicon spectrometer (RRMD-III). Radiat Res 162, 687-692 (2004).
5. 3:C optically stimulated luminescence (OSL) detectors. Phys Med Biol 55, 4963-4976 (2010).
6. Spurny, F., Molokanov, A. G., Bamblevski, V. P. Passive spectrometry of linear energy transfer: development and use. Radiat Prot Dosimetry 110, 675-679 (2004).
7. Bilski, P. Dosimetry of densely ionising radiation with three LiF phosphors for space applications. Radiat Prot Dosimetry 120, 397-400 (2006).
8. ICRU (International Commission on Radiation Units and Measurement) Clinical proton dosimetry. Part I: beam production, beam delivery and measurement of absorbed dose. ICRU Report No. 59 (1998).
9. Yukihara, E. G., McKeever, S. W. S. Optically stimulated thermoluminescence: Fundamentals and applications. John Wiley & Sons, Ltd., Chichester, UK (2011).
10. Gustavsson, H., Bjack, S. A. J., Medin, J., Grusell, E., Olsson, L. E. Linear energy transfer dependence of a normoxic polymer gel dosimeter investigated using proton beam absorbed dose measurements. Phys Med Biol 49, 3847-3855 (2004).
11. Heufelder, J., Stiefel, S., Pfaender, M., Ludemann, L., Grebe, G., Heese, J. Use of BANG(R) polymer gel for dose measurements in a 68 MeV proton beam. Med Phys 30, 1235-1240 (2003).
12. Archambault, L., Polf, J. C., Beaulieu, L., Beddar, S. Characterizing the response of miniature scintillation detectors when irradiated with proton beams. Phys Med Biol 53, 1865-1876 (2008).
13. Vatnitsky, S. M. Radiochromic film dosimetry for clinical proton beams. Appl Rad Isotopes 48, 643-651 (1997).
14. Veronese, I., Cantone, M. C., Chiodini, N., Coray, A., Fasoli, M., Lomax, A., Mones, E., Moretti, F., Vedda, A. Feasibility study for the use of cerium-doped silica fibres in proton therapy. Radiat Meas 45, 635-639 (2010).
15. Zeidan, O. A., Sriprisan, S. I., Lopatiuk-Tirpak, O., Kupelian, P. A., Meeks, S. L., Hsi, W. C., Li, Z., Palta, J. R., Maryanski, M. J. Dosimetric evaluation of a novel polymer gel dosimeter for proton therapy. Med Phys 37, 2145-2152 (2010).
16. Wilkens, J. J., Oelfke, U. Analytical linear energy transfer calculations for proton therapy. Med Phys 30, 806-815 (2003).
17. Bortfeld, T. An analytical approximation of the bragg curve for therapeutic proton beams. Med Phys 24, 2024-2033 (1997).
18. Gardey, K.-U., Oelfke, U., Lam, G. K. Y. Range modulation in proton therapy-an optimization technique for clinical and experimental applications. Phys Med Biol 44, N81-N88 (1999).
19. Maryanski, M. J., Zastavker, Y. Z., Gore, J. C. Radiation dose distributions in three dimensions from tomographic optical density scanning of polymer gels: II. Optical properties of the BANG polymer gel. Phys Med Biol 41, 2705-2717 (1996).