Mesenchymal stem cells are a rescue approach for recovery of deteriorating kidney function

Nephrology

Volumn 17, Issue 7, 2012, Pages 650-657

  El Ansary, Mervat ^a   Saadi, Gamal ^a   Abd El Hamid, Samah M ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

chronic kidney disease; glomerulonephritis; MSCs; renal transplantation; tissue repair

Indexed keywords

ADAPALENE; BETA1 INTEGRIN; CREATININE;

ADULT; AGED; ARTICLE; BONE MARROW BIOPSY; CELL ISOLATION; CHRONIC KIDNEY DISEASE; CLINICAL ARTICLE; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; FEMALE; GLOMERULONEPHRITIS; HUMAN; HUMAN CELL; HUMAN TISSUE; ILIAC BONE; KIDNEY FUNCTION; KIDNEY TRANSPLANTATION; MALE; MESENCHYMAL STEM CELL; PILOT STUDY; PRIORITY JOURNAL; SYSTEMIC LUPUS ERYTHEMATOSUS;

ADULT; AGED; ANTIGENS, CD29; BIOLOGICAL MARKERS; CELL SEPARATION; CELLS, CULTURED; CREATININE; EGYPT; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; KIDNEY; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MIDDLE AGED; NERVE TISSUE PROTEINS; PILOT PROJECTS; RECEPTORS, NERVE GROWTH FACTOR; RECOVERY OF FUNCTION; RENAL INSUFFICIENCY, CHRONIC; TIME FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84865853720     PISSN: 13205358     EISSN: 14401797     Source Type: Journal    
DOI: 10.1111/j.1440-1797.2012.01622.x     Document Type: Article

References (24)

1. El Nahas AM, Bello AK,. Chronic kidney disease: The global challenge. Lancet 2005; 365: 331-40. (Pubitemid 40139112)
2. Romagnani P,. Toward the identification of a 'renopoietic system'? Stem Cells 2009; 27: 2247-53.
3. Kuci S, Kuci Z, Latifi-Pupovci H, et al,. Adult stem cells as an alternative source of multipotential (pluripotential) cells in regenerative medicine. Curr. Stem Cell Res. Ther. 2009; 4: 107-17.
4. Sagrinati C, Netti GS, Mazzinghi B, et al,. Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys. J. Am. Soc. Nephrol. 2006; 17: 2443-56. (Pubitemid 44300960)
5. Bi B, Schmitt R, Israilova M, et al,. Stromal cells protect against acute tubular injury via an endocrine effect. J. Am. Soc. Nephrol. 2007; 18: 2486-96. (Pubitemid 47378865)
6. Imberti B,. Insulin-like growth factor-1 sustains stem cell mediated renal repair. J. Am. Soc. Nephrol. 2007; 18: 2921-8. (Pubitemid 350058399)
7. Okuyama H, Krishnamachary B, Zhou YF, et al,. Expression of vascular endothelial growth factor receptor 1 in bone marrow-derived mesenchymal cells is dependent on hypoxia-inducible factor 1. J. Biol. Chem. 2006; 281: 15554-63. (Pubitemid 43855148)
8. Togel F, Hu Z, Weiss K, et al,. Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am. J. Physiol. Renal Physiol. 2005; 289: F31-42. (Pubitemid 40863570)
9. Ben-Ami E, Berrih-Aknin S, Miller A,. Mesenchymal stem cells as an immunomodulatory therapeutic strategy for autoimmune diseases. Autoimmun. Rev. 2011; 10: 410-5.
10. Bruno S, Grange C, Deregibus MC, et al,. Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J. Am. Soc. Nephrol. 2009; 20: 1053-67.
11. Jordan F, McWhinnie AG, Turner S, et al,. Comparison of HLA-DRB1 typing by DNA-RFLP, PCR-SSO and PCR-SSP methods and their application in providing matched unrelated donors for bone marrow transplantation. Tissue Antigens 2008; 45: 103-10.
12. Sagrinati C, Ronconi E, Lazzeri E, et al,. Stem-cell approaches for kidney repair: Choosing the right cells. Trends Mol. Med. 2008; 14: 277-85.
13. Humphreys BD, Bonventre JV,. The contribution of adult stem cells to renal repair. Nephrol. Ther. 2007; 3: 3-10. (Pubitemid 46454395)
14. Bühring HJ, Battula VL, Treml S, et al,. Novel markers for the prospective isolation of human MSC. Ann. N. Y. Acad. Sci. 2007; 1106: 262-71. (Pubitemid 47443036)
15. Di Nicola M, Carlo-Stella C, Magni M, et al,. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 2002; 99: 3838-43. (Pubitemid 34534559)
16. Le Blanc K, Frassoni F, Ball L, et al,. Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: A phase II study. Lancet 2008; 371: 1579-86. (Pubitemid 351626841)
17. Togel F, Westenfelder C,. Mesenchymal stem cells: A new therapeutic tool for AKI. Nat. Rev. Nephrol. 2010; 6: 179-83.
18. Chhabra P, Brayman KL,. The use of stem cells in kidney disease. Curr. Opin. Organ Transplant. 2009; 14: 72-8.
19. Morigi M, Introna M, Imberti B, et al,. Human bone marrow mesenchymal stem cells accelerate recovery of acute renal injury and prolong survival in mice. Stem Cells 2008; 26: 2075-82.
20. Togel F, Weiss K, Yang Y, et al,. Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injury. Am. J. Physiol. Renal Physiol. 2007; 292: F1626-35. (Pubitemid 46701891)
21. Pino CJ, David HD,. Stem cell technology for the treatment of acute and chronic renal failure. Transl. Res. 2010; 156: 161-8.
22. Bartholomew A, Sturgeon C, Siatskas M, et al,. Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Exp. Hematol. 2002; 30: 42-8. (Pubitemid 34059216)
23. Uccelli A, Pistoia V, Moretta L,. Mesenchymal stem cells: A new strategy for immunosuppression? Trends Immunol. 2007; 28: 219-26. (Pubitemid 46667240)
24. Adams KM, Nelson JL,. Microchimerism: An investigative frontier in autoimmunity and transplantation. JAMA 2004; 291: 1127-31. (Pubitemid 38541691)