Epinephrine auto-injector pandemic

Pediatric Emergency Care

Volumn 28, Issue 9, 2012, Pages 938-942

  Campbell, Ronna L ^a   Manivannan, Veena ^a   Hartz, Martha F ^a   Sadosty, Annie T ^a  

^a MAYO CLINIC   (United States)

Author keywords

epinephrine auto injector; indications; unintentional use

Indexed keywords

ADRENALIN; EPIPEN JR; EPIPENS; UNCLASSIFIED DRUG;

ANAPHYLAXIS; AWARENESS; DRUG USE; FOOD ALLERGY; HUMAN; NEEDLESTICK INJURY; NORTH AMERICA; PRESCRIPTION; REVIEW; TREATMENT INDICATION;

ADRENERGIC AGONISTS; ANAPHYLAXIS; DRUG PRESCRIPTIONS; EPINEPHRINE; HUMANS; INJECTIONS, INTRAMUSCULAR; SELF ADMINISTRATION;

EID: 84865849104     PISSN: 07495161     EISSN: 15351815     Source Type: Journal    
DOI: 10.1097/PEC.0b013e318267f689     Document Type: Review

References (38)

1. Lieberman P, Camargo CA Jr, Bohlke K, et al. Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working Group. Ann Allergy Asthma Immunol. 2006;97:596Y602.
2. Campbell RL, Luke A,Weaver AL, et al. Prescriptions for self-injectable epinephrine and follow-up referral in emergency department patients presenting with anaphylaxis. Ann Allergy Asthma Immunol. 2008;101:631Y636.
3. Bohlke K, Davis RL, DeStefano F, et al. Epidemiology of anaphylaxis among children and adolescents enrolled in a health maintenance organization. J Allergy Clin Immunol. 2004;113:536Y542.
4. Kemp SF, Lockey RF, Simons FE. Epinephrine: the drug of choice for anaphylaxis. A statement of the World Allergy Organization. Allergy. 2008;63:1061Y1070.
5. Simons FE. First-aid treatment of anaphylaxis to food: focus on epinephrine. J Allergy Clin Immunol. 2004;113:837Y844.
6. Simons FE, Peterson S, Black CD. Epinephrine dispensing patterns for an out-of-hospital population: a novel approach to studying the epidemiology of anaphylaxis. J Allergy Clin Immunol. 2002;110:647Y651.
7. Camargo CA Jr, Clark S, Kaplan MS, et al. Regional differences in EpiPen prescriptions in the United States: the potential role of vitamin D. J Allergy Clin Immunol. 2007;120:131Y136.
8. Kemp AS. EpiPen epidemic: suggestions for rational prescribing in childhood food allergy. J Paediatr Child Health. 2003;39:372Y375.
9. Levy Y, Segal N, Danon YL. Trends in adrenaline (EpiPen) dispensing in Israel in 1997Y2004. Public Health. 2007;121:144Y147.
10. Gupta R, Sheikh A, Strachan DP, et al. Time trends in allergic disorders in the UK. Thorax. 2007;62:91Y96.
11. Sheikh A, Hippisley-Cox J, Newton J, et al. Trends in national incidence, lifetime prevalence and adrenaline prescribing for anaphylaxis in England. J R Soc Med. 2008;101:139Y143.
12. YocumMW, Butterfield JH, Klein JS, et al. Epidemiology of anaphylaxis in Olmsted County: A population-based study [see comment]. J Allergy Clin Immunol. 1999;104(2 pt 1):452Y456.
13. Mulla ZD, Lin RY, Simon MR. Perspectives on anaphylaxis epidemiology in the United States with new data and analyses. Curr Allergy Asthma Rep. 2011;11:37Y44.
14. Clark S, Camargo CA Jr. Epidemiology of anaphylaxis. Immunol Allergy Clin North Am. 2007;27:145Y163.
15. Decker WW, Campbell RL, Manivannan V, et al. The etiology and incidence of anaphylaxis in Rochester, Minnesota: a report from the Rochester Epidemiology Project. J Allergy Clin Immunol. 2008;122:1161Y1165.
16. Gaeta TJ, Clark S, Pelletier AJ, et al. National study of US emergency department visits for acute allergic reactions, 1993 to 2004. Ann Allergy Asthma Immunol. 2007;98:360Y365.
17. Klein JS, Yocum MW. Underreporting of anaphylaxis in a community emergency room. J Allergy Clin Immunol. 1995;95:637Y638.
18. Clark S, Bock SA, Gaeta TJ, et al. Multicenter study of emergency department visits for food allergies. J Allergy Clin Immunol. 2004;113:347Y352.
19. Clark S, Long AA, Gaeta TJ, et al. Multicenter study of emergency department visits for insect sting allergies. J Allergy Clin Immunol. 2005;116:643Y649.
20. Sampson HA, Munoz-Furlong A, Campbell RL, et al. Second symposium on the definition and management of anaphylaxis: summary reportVsecond National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. Ann Emerg Med. 2006;47:373Y380.
21. Branum AM, Lukacs SL. Food allergy among US children: trends in prevalence and hospitalizations. NCHS Data Brief. 2008;10:1Y8.
22. Liew WK, Williamson E, Tang ML. Anaphylaxis fatalities and admissions in Australia. J Allergy Clin Immunol. 2009;123:434Y442.
23. Sicherer SH, Munoz-Furlong A, Godbold JH, et al. US prevalence of self-reported peanut, tree nut, and sesame allergy: 11-year follow-up. J Allergy Clin Immunol. 2010;125:1322Y1326.
24. Gupta RS, Springston EE, Warrier MR, et al. The prevalence, severity, and distribution of childhood food allergy in the United States. Pediatrics. 2011;128:e9Ye17.
25. Rona RJ, Keil T, Summers C, et al. The prevalence of food allergy: a meta-analysis. J Allergy Clin Immunol. 2007;120:638Y646.
26. Food Allergy & Anaphylaxis Alliance. Available at: http://www.foodallergyalliance.org/abo.html. Accessed February 16, 2012.
27. Boyce JA, Assa'ad A, Burks AW, et al. Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. J Allergy Clin Immunol. 2010;126(suppl 6):S1YS58.
28. Cianferoni A, Muraro A. Food-induced anaphylaxis. Immunol Allergy Clin North Am. 2012;32:165Y195.
29. ASCIA Guidelines for adrenaline autoinjector prescription. 2009. Available at: http://www.allergy.org.au/content/view/11/319/. Accessed September 29, 2011.
30. Muraro A, Roberts G, Clark A, et al. The management of anaphylaxis in childhood: position paper of the European academy of allergology and clinical immunology. Allergy. 2007;62:857Y871.
31. Simons FE, Edwards ES, Read EJ Jr, et al. Voluntarily reported unintentional injections from epinephrine auto-injectors. J Allergy Clin Immunol. 2010;125:419Y423.
32. Simons FE, Lieberman PL, Read EJ Jr, et al. Hazards of unintentional injection of epinephrine from autoinjectors: a systematic review. Ann Allergy Asthma Immunol. 2009;102:282Y287.
33. Fitzcharles-Bowe C, Denkler K, Lalonde D. Finger injection with high-dose (1:1000) epinephrine: does it cause finger necrosis and should it be treated? Hand (N Y). 2007;2:5Y11.
34. Arkwright PD, Farragher AJ. Factors determining the ability of parents to effectively administer intramuscular adrenaline to food allergic children. Pediatr Allergy Immunol. 2006;17:227Y229.
35. Mehr S, Robinson M, Tang M. Doctor, how do I use my EpiPen? Pediatr Allergy Immunol. 2007;18:448Y452.
36. Frew AJ. What are the ''ideal'' features of an adrenaline (epinephrine) auto-injector in the treatment of anaphylaxis? Allergy. 2011;66:15Y24.
37. Guerlain S, Hugine A, Wang L. A comparison of 4 epinephrine autoinjector delivery systems: usability and patient preference. Ann Allergy Asthma Immunol. 2010;104:172Y177.
38. Guerlain S, Wang L, Hugine A. Intelliject's novel epinephrine autoinjector: sharps injury prevention validation and comparable analysis with EpiPen and Twinject. Ann Allergy Asthma Immunol. 2010;105:480Y484.