Neuro-glial and systemic mechanisms of pathological responses in rat models of primary blast overpressure compared to "composite" blast

Frontiers in Neurology

Volumn FEB, Issue , 2012, Pages

  Svetlov, Stanislav I ^a,b   Prima, Victor ^a   Glushakova, Olena ^a   Svetlov, Artem ^a   Kirk, Daniel R ^c   Gutierrez, Hector ^c   Serebruany, Victor L ^d   Curley, Kenneth C ^e   Wang, Kevin K W ^b   Hayes, Ronald L ^a  

^a Banyan Laboratories Inc   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c Florida Institute of Technology   (United States)

^d Heart Drug Research LLC   (United States)

^e U S ARMY MEDICAL RESEARCH AND MATERIEL COMMAND   (United States)

Author keywords

Biomarkers; Blast; Brain injury; Neuro glia damage; Rat models; Systemic responses

Indexed keywords

EID: 84865841967     PISSN: None     EISSN: 16642295     Source Type: Journal    
DOI: 10.3389/fneur.2012.00015     Document Type: Article

References (45)

1. Bannerman, P., Ara, J., Hahn, A., Hong, L., McCauley, E., Friesen, K., and Pleasure, D. (2008). Peripheral nerve regeneration is delayed in neuropilin 2-deficient mice. Neurosd. Res. 86, 3163-3169.
2. Bass, C.R., Panzer, M.B., Rafaels, K.A., Wood, G., Shridharani, J., and Capehart, B. (2012). Brain injuries from blast. Ann. Biotned. Eng. 40, 185-202.
3. Belanger, H.G., Scott, S.G., Scholten, J., Curtiss, G., and Vanderploeg, R.D. (2005). Utility of mechanism-of-injury-based assessment and treatment: Blast Injury Program case illustration. Rehabil. Res. Dev. 42, 403-412.
4. Born, C.T. (2005). Blast trauma: the fourth weapon of mass destruction. Scand. J. Surg. 94, 279-285.
5. Calissano, P., and Matrone, C, Amadoro, G. (2010). Nerve growth factor as a paradigm of neu-rotrophins related to Alzheimer's disease. Dev. Neurobiol. 70, 372-383.
6. Cernak, I.(2010). The importance of systemic response in the pathobiology of blast-induced neurotrauma. Front. Neurol. 1:151. doi:10.3389/fneur.2010.00151
7. Cernak, I., Merkle, A.C, Koliatsos, V.E., Bilik, J.M., Luong, Q.T., Mahota, T. M., Xu, L., Slack, N., Windle, D., and Ahmed, F.A. (2011). The pathobiology of blast injuries and blast-induced neurotrauma as identified using a new experimental model of injury in mice. Neurobiol. Dis. 41, 538-551.
8. Cernak, I., and Noble-Haeusslein, L.J. (2010). Traumatic brain injury: an overview of pathobiology with emphasis on military populations. Cereb. Blood Flow Metab. 30, 255-266.
9. Cernak, I., Savic, J., Ignjatovic, D., and Jevtic, M. (1999). Blast injury from explosive munitions. Trauma. 47, 96-103; discussion 103-104.
10. Chavko, M., Adeeb, S., Ahlers, S.T., and McCarron, R.M. (2009). Attenuation of pulmonary inflammation after exposure to blast overpressure by N-acetylcysteine amide. Shock 32, 325-331.
11. Cloutier, J.E, Giger, R.J., Koentges, G., Dulac, C., Kolodkin, A.L., and Ginty, D.D. (2002). Neuropilin-2 mediates axonal fasciculation, zonal segregation, but not axonal convergence, of primary accessory olfactory neurons. Neuron 33, 877-892.
12. Dietrich, W.D., Chatzipanteli, K., Vitarbo, E., Wada, K., and Kinoshita, K. (2004). The role of inflammatory processes in the pathophysi-ology and treatment of brain and spinal cord trauma. Ada Neurochir. Suppl. 89, 69-74.
13. Elsayed, N.M. (1997). Toxicology of blast overpressure. Toxicology 121, 1-15.
14. Garman, R.H., Jenkins, L.W., Switzer, R.C, Bauman, R.A., Tong, L.C, Swauger, P.W., Parks, S.A., Ritzel, D.V., Dixon, C.E., Clark, R.S.B., Bayir, H., Kagan, V., Jackson, E.K., and Kochanek, P.M. (2011). Blast exposure in rats with body shielding is characterized primarily by diffuse axonal injury. Neurotrauma 28, 947-959.
15. Guy, R.J., Glover, M.A., and Cripps, N.P. (1998a). The pathophysiol-ogy of primary blast injury and its implications for treatment. Part I: the thorax. R. Nav. Med. Serv. 84, 79-86.
16. Guy, R.J., Kirkman, E., Watkins, P.E., and Cooper, G.J. (1998b). Physiologic responses to primary blast. Trauma. 45, 983-987.
17. Gyorgy, A., Ling, G., Wingo, D., Walker, J., Tong, L., Parks, S., Januszkiewicz, A., Baumann, R., and Agoston, D. V. (2011). Time-dependent changes in serum biomarker levels after blast traumatic brain injury. Neurotrauma 28, 1121-1126.
18. Hurley, R.A., McGowan, J.C, Arfanakis, K., Taber, K.H. (2004). Traumatic axonal injury: novel insights into evolution and identification. Neuropsychiatry Clin. Neurosd. 16, 1-7.
19. Jaffin, J.H., McKinney, L., Kinney, R.C, Cunningham, J.A., Moritz, D.M., Kraimer, J.M., Graeber, G.M., Moe, J.B., Salander, J.M., and Harmon, J.W (1987). A laboratory model for studying blast overpressure injury. Trauma. 27, 349-356.
20. Jones, E., Fear, N.T., and Wessely, S. (2007). Shell shock and mild traumatic brain injury: a historical review. Am. J. Psychiatry 164, 1641-1645.
21. Kinney, G.F. (1985). Explosive Shocks in Air. New York:Spinger-Verlag.
22. Kwon, S.K., Kovesdi, E., Gyorgy, A.B., Wingo, D., Kamnaksh, A., Walker, J., Long, J.B., andAgoston, D.V. (2011). Stress and traumatic brain injury: a behavioral, proteomics, and his-tological study. Front. Neurol. 2:12. doi:10.3389/fneur.2011.00012
23. Li, Y., Zhang, S.F., Zou, S.E., Xia, X., Bao, L. (2007). Accumulation of nerve growth factor and its receptors in the uterus and dorsal root ganglia in a mouse model of adenomyosis. Reprod. Biol. Endocrinol 9, 30.
24. Liu, M.C, Akinyi, L., Scharf, D., Mo, J., Lamer, S.E, Muller, U., Oh, M.W, Zheng, W., Kobeissy, E, Papa, L., Lu, X.C, Dave, J.R., Tortella, F.C, Hayes, R.L., and Wang, K.K. (2010). Ubiquitin C-terminal hydrolase-Ll as a biomarker for ischemic and traumatic brain injury in rats. Eur.]. Neurosd. 31, 722-732.
25. Maegele, M., Sauerland, S., Bouillon, B., Schafer, U., Trubel, H., Riess, P., and Neugebauer, E.A. (2007). Differential immunoresponses following experimental traumatic brain injury, bone fracture and "two-hit"-combined neurotrauma. Inflamm. Res. 56, 318-323.
26. Nelson, T.J., Wall, D.B., Stedje-Larsen, E.T., Clark, R.T., Chambers, L.W., and Bohman, H.R. (2006). Predictors of mortality in close proximity blast injuries during Operation Iraqi Freedom. Am. Coll. Surg. 202, 418-422.
27. Nottet, H.S. (1999). Interactions between macrophages and brain microvascular endothelial cells: role in pathogenesis of HIV-1 infection and blood - brain barrier function. Neurovirol. 5, 659-669.
28. Ralay Ranaivo, H., Zunich, S., Choi, N., Hodge, J., Wainwright, M. (2011). Mild stretch-induced injury increases susceptibility to interleukin- lbeta-induced release of matrix metalloproteinase-9 from astrocytes. J. Neurotrauma. 28, 1757-1766.
29. Rancan, M., Bye, N., Otto, V.I., Trentz, O., Kossmann, T., Frentzel, S., and Morganti-Kossmann, M.C. (2004). The chemokine fractalkine in patients with severe traumatic brain injury and a mouse model of closed head injury. Cereb. Blood Flow Metab. 24, 1110-1118.
30. Roffers-Agarwal, J., and Gammill, L.S. (2009). Neuropilin receptors guide distinct phases of sensory and motor neuronal segmentation. Development 136, 1879-1888.
31. Savic, J., Tatic, V., Ignjatovic, D., Mrda, V., Erdeljan, D., Cernak, I., Vujnov, S., Simovic, M., Andelic, G., and Duknic, M. (1991). Pathophysio-logic reactions in sheep to blast waves from detonation of aerosol explosives. Vojnosanit. Pregl. 48, 499-506.
32. Stuhmiller, J.H., Ho, K.H., Vander Vorst, M.J., Dodd, K.T., Fitzpatrick, T., and Mayorga, M. (1996).Amodel of blast overpressure injury to the lung. Biomech. 29, 227-234.
33. Svetlov, S.I, Prima, V., Kirk, D.R., Gutierrez, H., Curley, K.C, Hayes, R.L, and Wang, K.K.W. (2011). "Neuro-glial and systemic mechanisms of pathological responses to primary blast overpressure (OP) compared to "composite" blast accompanied by head acceleration in rats, "in Proceeding of NATO conference 'A Survey of Blast Injury across the Full Landscape of Military Science http://www.rto.nato.int/
34. Svetlov, S.I., Larner, S.E, Kirk, D.R., Atkinson, J., Hayes, R.L., and Wang, K.K. (2009). Biomarkers of blast-induced neurotrauma: profiling molecular and cellular mechanisms of blast brain injury. Neurotrauma 26, 913-921.
35. Svetlov, S.I., Prima, V., Kirk, D.R., Gutierrez, H., Curley, K.C, Hayes, R. L., and Wang, K.K. (2010). Morphologic and biochemical characterization of brain injury in a model of controlled blast overpressure exposure. Trauma. 69, 795-804.
36. Syed, Z., Dudbridge, R, and Kent, L. (2007). An investigation of the neu-rotrophic factor genes GDNF, NGF, and NT3 in susceptibility to ADHD. Am. J. Med. Genet. B Neuropsychiatr. Genet. 144B, 375-378.
37. Terrio, H., Brenner, L.A., Ivins, B.J., Cho, J.M., Helmick, K., Schwab, K., Scally, K., Bretthauer, R., Warden, D. (2009). Traumatic brain injury screening: preliminary findings in a US Army Brigade Combat Team. Head Trauma Rehabil. 24, 14-23.
38. Urrea, C, Castellanos, D.A., Sagen, J., Tsoulfas, P., Bramlett, H.M., and Dietrich, W.D. (2007). Widespread cellular proliferation and focal neurogenesis after traumatic brain injury in the rat. Restor. Neurol. Neurosd. 25, 65-76.
39. Utagawa, A., Bramlett, H.M., Daniels, L., Lotocki, G., Dekaban, G.A., Weaver, L.C, and Dietrich, W.D., (2008). Transient blockage of the CD 1 Id/CD 18 integrin reduces contusion volume and macrophage infiltration after traumatic brain injury in rats. Brain Res. 1207, 155-163.
40. Vander Vorst, M., Ono, K., Chan, P., and Stuhmiller, J. (2007). Correlates to traumatic brain injury in nonhuman primates. Trauma 62, 199-206.
41. Warden, D. (2006). Military TBI during the Iraq and Afghanistan wars. Head Trauma Rehabil. 21, 398-402.
42. Whalen, M.J., Carlos, T.M., Dixon, C.E., Robichaud, P., Clark, R.S., Marion, D.W, and Kochanek, P.M. (2000). Reduced brain edema after traumatic brain injury in mice deficient in P-selectin and intercellular adhesion molecule-1. Leukoc. Biol. 67, 160-168.
43. Whalen, M.J., Carlos, T.M., Kochanek, P.M., Clark, R.S., Heineman, S., Schiding, J.K., Franicola, D., Memarzadeh, E, Lo, W, Marion, D.W, and Dekosky, S.T. (1999). Neutrophils do not mediate blood-brain barrier permeability early after controlled cortical impact in rats. Neurotrauma 16, 583-594.
44. Wolf, S.J., Bebarta, V.S., Bonnett, C.J., Pons, P.T., and Cantrill, S.V. (2009). Blast injuries. Lancet 374, 405-415.
45. Yilmaz, S., and Pekdemir, M. (2007). An unusual primary blast injury Traumatic brain injury due to primary blast injury. Am. J. Emerg. Med. 25, 97-98.