Pain Processing in the Human Nervous System. A Selective Review of Nociceptive and Biobehavioral Pathways

Primary Care - Clinics in Office Practice

Volumn 39, Issue 3, 2012, Pages 561-571

  Garland, Eric L ^a  

^a FLORIDA STATE UNIVERSITY   (United States)

Author keywords

Affective; Autonomic; Cognitive; Neurobiology; Nociception; Pain

Indexed keywords

AUTONOMIC NERVOUS SYSTEM; BEHAVIOR; CENTRAL NERVOUS SYSTEM; COGNITION; EMOTION; HUMAN; NEUROANATOMY; NEUROBIOLOGY; NEUROCHEMISTRY; NOCICEPTION; PAIN; PATHOPHYSIOLOGY; PERIPHERAL NERVOUS SYSTEM; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; PSYCHOPHYSIOLOGY; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION;

ADAPTATION, PSYCHOLOGICAL; AFFECT; AUTONOMIC NERVOUS SYSTEM; BEHAVIOR THERAPY; CHRONIC DISEASE; COGNITION; EMOTIONS; HUMANS; LOW BACK PAIN; NEUROANATOMY; NEUROBIOLOGY; NOCICEPTIVE PAIN; PERCEPTION; STRESS, PSYCHOLOGICAL;

EID: 84865841765     PISSN: 00954543     EISSN: 1558299X     Source Type: Journal    
DOI: 10.1016/j.pop.2012.06.013     Document Type: Review

References (72)

1. Merskey H., Bogduk N. Classification of chronic pain, IASP Task Force on Taxonomy 1994, IASP Press, Seattle (WA).
2. Brodal P. The central nervous system: structure and function 2010, Oxford University Press.
3. Loeser J.D., Melzack R. Pain: an overview. The Lancet 1999, 353(9164):1607-1609.
4. Bishop G.H., Landau W.M. Evidence for a double peripheral pathway for pain. Science 1958, 128(3326):712-713.
5. Sherman S.M., Guillery R. Functional organization of thalamocortical relays. J Neurophysiol 1996, 76(3):1367.
6. Willis W., Westlund K. Neuroanatomy of the pain system and of the pathways that modulate pain. J Clin Neurophysiol 1997, 14(1):2.
7. Tracey I., Mantyh P.W. The cerebral signature for pain perception and its modulation. Neuron 2007, 55(3):377-391.
8. Melzack R. From the gate to the neuromatrix. Pain 1999, 82:S121-S126.
9. Petrenko A.B., Yamakura T., Baba H., et al. The role of N-methyl-D-aspartate (NMDA) receptors in pain: a review. Anesth Analg 2003, 97(4):1108.
10. JM B. The neurobiology of pain. The Lancet 1999, 353(9164):1610-1615.
11. Yaksh T.L. Pharmacology of spinal adrenergic systems which modulate spinal nociceptive processing. Pharmacol Biochem Behav 1985, 22(5):845-858.
12. Voisin D.L., Guy N., Chalus M., et al. Nociceptive stimulation activates locus coeruleus neurones projecting to the somatosensory thalamus in the rat. J Physiol 2005, 566(3):929-937.
13. Yaksh T.L. Opioid receptor systems and the endorphins: a review of their spinal organization. J Neurosurg 1987, 67(2):157-176.
14. Basbaum A.I., Fields H.L. Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. Annu Rev Neurosci 1984, 7(1):309-338.
15. Jasmin L., Rabkin S.D., Granato A., et al. Analgesia and hyperalgesia from GABA-mediated modulation of the cerebral cortex. Nature 2003, 424(6946):316-320.
16. Heinricher M., Tavares I., Leith J., et al. Descending control of nociception: specificity, recruitment and plasticity. Brain Res Rev 2009, 60(1):214-225.
17. Melzack R., Wall P.D. Pain mechanisms: a new theory. Science 1965, 150(699):971-979.
18. Reynolds D.V. Surgery in the rat during electrical analgesia induced by focal brain stimulation. Science 1969, 164(3878):444.
19. Carlson J.D., Maire J.J., Martenson M.E., et al. Sensitization of pain-modulating neurons in the rostral ventromedial medulla after peripheral nerve injury. J Neurosci 2007, 27(48):13222.
20. Desimone R., Duncan J. Neural mechanisms of selective visual attention. Annu Rev Neurosci 1995, 18:193-222.
21. Corbetta M., Shulman G.L. Control of goal-directed and stimulus-driven attention in the brain. Nat Rev Neurosci 2002, 3:201-215.
22. Friedman R.S., Förster J. Implicit affective cues and attentional tuning: an integrative review. Psychol Bull 2010, 136(5):875.
23. Lang P.J., Bradley M.M. Emotion and the motivational brain. Biol Psychol 2011, 84:437-450.
24. Legrain V., Perchet C., García-Larrea L. Involuntary orienting of attention to nociceptive events: neural and behavioral signatures. J Neurophysiol 2009, 102(4):2423.
25. Eccleston C., Crombez G. Pain demands attention: a cognitive-affective model of the interruptive function of pain. Psychol Bull 1999, 125(3):356.
26. Quevedo A.S., Coghill R.C. Attentional modulation of spatial integration of pain: evidence for dynamic spatial tuning. J Neurosci 2007, 27(43):11635-11640.
27. Terkelsen A.J., Andersen O.K., Mølgaard H. Mental stress inhibits pain perception and heart rate variability but not a nociceptive withdrawal reflex. Acta Physiol Scand 2004, 180(4):405-414.
28. Wiech K., Ploner M., Tracey I. Neurocognitive aspects of pain perception. Trends in Cognitive Sciences 2008, 12(8):306-313.
29. Schoth D.E., Nunes V.D., Liossi C. Attentional bias towards pain-related information in chronic pain; a meta-analysis of visual-probe investigations. Clin Psychol Rev 2012, 32(1):13-25. [Epub 2011 Sep 17].
30. Hollins M., Harper D., Gallagher S., et al. Perceived intensity and unpleasantness of cutaneous and auditory stimuli: an evaluation of the generalized hypervigilance hypothesis. Pain 2009, 141(3):215-221.
31. Rollman G.B. Perspectives on hypervigilance. Pain 2009, 141(3):183-184.
32. Rainville P., Carrier B., Hofbauer R.K., et al. Dissociation of sensory and affective dimensions of pain using hypnotic modulation. Pain 1999, 82:159-171.
33. Rainville P., Duncan G.H., Price D.D., et al. Pain affect encoded in human anterior cingulate but not somatosensory cortex. Science 1997, 277:968-971.
34. Price D.D. Central neural mechanisms that interrelate sensory and affective dimensions of pain. Mol Interv 2002, 2(6):392-403.
35. Ochsner K.N., Gross J.J. The cognitive control of emotion. Trends Cogn Sci 2005, 9:242-249.
36. Kalisch R. The functional neuroanatomy of reappraisal: time matters. Neurosci Biobehav Rev 2009, 33:1215-1226.
37. Haythornthwaite J.A., Menefee L.A., Heinberg L.J., et al. Pain coping strategies predict perceived control over pain. Pain 1998, 77(1):33-39.
38. Garland E.L., Gaylord S.A., Palsson O., et al. Therapeutic mechanisms of a mindfulness-based treatment for IBS: effects on visceral sensitivity, catastrophizing, and affective processing of pain sensations. J Behav Med 2011, 1-12.
39. Severeijns R., Vlaeyen J.W., van den Hout M.A., et al. Pain catastrophizing predicts pain intensity, disability, and psychological distress independent of the level of physical impairment. Clin J Pain 2001, 17(2):165.
40. Picavet H.S., Vlaeyen J.W., Schouten J.S. Pain catastrophizing and kinesiophobia: predictors of chronic low back pain. Am J Epidemiol 2002, 156(11):1028-1034.
41. Tousignant-Laflamme Y., Marchand S. Sex differences in cardiac and autonomic response to clinical and experimental pain in LBP patients. Eur J Pain 2006, 10(7):603-614.
42. Flor H., Turk D.C., Birbaumer N. Assessment of stress-related psychophysiological reactions in chronic back pain patients. J Consult Clin Psychol 1985, 53(3):354-364.
43. Lundberg U., Dohns I.E., Melin B., et al. Psychophysiological stress responses, muscle tension, and neck and shoulder pain among supermarket cashiers. J Occup Health Psychol 1999, 4(3):245-255.
44. Rainville P., Bao Q.V., Chrétien P. Pain-related emotions modulate experimental pain perception and autonomic responses. Pain 2005, 118(3):306-318.
45. Cannon W.B. Organization of physiological homeostasis. Physiol Rev 1929, 9:399-431.
46. Benarroch E.E. Pain-autonomic interactions. Neurol Sci 2006, 27(Suppl 2):s130-s133.
47. Sommer C., Kress M. Recent findings on how proinflammatory cytokines cause pain: peripheral mechanisms in inflammatory and neuropathic hyperalgesia. Neurosci Lett 2004, 361(1-3):184-187.
48. Chapman C.R., Tuckett R.P., Song C.W. Pain and stress in a systems perspective: reciprocal neural, endocrine, and immune interactions. J Pain 2008, 9(2):122-145.
49. Craig A.D. Interoception: the sense of the physiological condition of the body. Curr Opin Neurobiol 2003, 13:500-505.
50. Wiech K., Tracey I. The influence of negative emotions on pain: behavioral effects and neural mechanisms. Neuroimage 2009, 47:987-994.
51. de Wied M., Verbaten M.N. Affective pictures processing, attention, and pain tolerance. Pain 2001, 90(1-2):163-172.
52. Kirwilliam S.S., Derbyshire S.W. Increased bias to report heat or pain following emotional priming of pain-related fear. Pain 2008, 137(1):60-65.
53. Bogaerts K., Janssens T., De Peuter S., et al. Negative affective pictures can elicit physical symptoms in high habitual symptom reporters. Psychol Health 2009, 25(6):685-698.
54. Panerai A.E. Pain emotion and homeostasis. Neurol Sci 2011, 32(Suppl 1):27-29.
55. Strigo I.A., Simmons A.N., Matthews S.C., et al. Increased affective bias revealed using experimental graded heat stimuli in young depressed adults: evidence of " emotional allodynia." Psychosom Med 2008, 70(3):338-344.
56. Keogh E., Ellery D., Hunt C., et al. Selective attentional bias for pain-related stimuli amongst pain fearful individuals. Pain 2001, 91:91-100.
57. Arnsten A.F. Stress signalling pathways that impair prefrontal cortex structure and function. Nat Rev Neurosci 2009, 10(6):410-422.
58. Lawrence J.M., Hoeft F., Sheau K.E., et al. Strategy-dependent dissociation of the neural correlates involved in pain modulation. Anesthesiology 2011, 115(4):844-851.
59. Keefe F.J., Wilkins R.H., Cook W.A. Direct observation of pain behavior in low back pain patients during physical examination. Pain 1984, 20(1):59-68.
60. Hadjistavropoulos T., Craig K.D., Fuchs-Lacelle S.K. Social influences and the communication of pain. Pain: Psychological perspectives 2004, Lawrence Erlbaum Associates, Mahwah (NJ), 87-112. T. Hadjistavropoulos, K.D. Craig (Eds.).
61. Turk D.C., Flor H. Pain greater than pain behaviors: the utility and limitations of the pain behavior construct. Pain 1987, 31(3):277-295.
62. Vlaeyen J.W., Linton S.J. Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art. Pain 2000, 85(3):317-332.
63. Linton S.J., Buer N., Vlaeyen J., et al. Are fear-avoidance beliefs related to the inception of an episode of back pain? a prospective study. Psychol Health 2000, 14(6):1051-1059.
64. Buer N., Linton S.J. Fear-avoidance beliefs and catastrophizing: occurrence and risk factor in back pain and ADL in the general population. Pain 2002, 99(3):485-491.
65. Klenerman L., Slade P., Stanley I., et al. The prediction of chronicity in patients with an acute attack of low back pain in a general practice setting. Spine 1995, 20(4):478.
66. Crombez G., Vlaeyen J.W., Heuts P.H., et al. Pain-related fear is more disabling than pain itself: evidence on the role of pain-related fear in chronic back pain disability. Pain 1999, 80(1-2):329-339.
67. Waddell G., Newton M., Henderson I., et al. A fear-avoidance beliefs questionnaire (FABQ) and the role of fear-avoidance beliefs in chronic low back pain and disability. Pain 1993, 52(2):157-168.
68. Vlaeyen J.W., Kole-Snijders A.M., Boeren R.G., et al. Fear of movement/(re)injury in chronic low back pain and its relation to behavioral performance. Pain 1995, 62(3):363-372.
69. Waddell G. Biopsychosocial analysis of low back pain. Baillieres Clin Rheumatol 1992, 6(3):523.
70. Hoffman B.M., Papas R.K., Chatkoff D.K., et al. Meta-analysis of psychological interventions for chronic low back pain. Health Psychol 2007, 26(1):1.
71. Waddell G., McCulloch J., Kummel E., et al. Nonorganic physical signs in low-back pain. Spine 1980, 5(2):117-125.
72. Waddell G. Low back pain: a twentieth century health care enigma. Spine 1996, 21(24):2820.