Assessment of the cross-protective capability of recombinant capsid proteins derived from pig, rat, and avian hepatitis E viruses (HEV) against challenge with a genotype 3 HEV in pigs

Vaccine

Volumn 30, Issue 44, 2012, Pages 6249-6255

  Sanford, Brenton J ^a   Opriessnig, Tanja ^b   Kenney, Scott P ^a   Dryman, Barbara A ^a   Córdoba, Laura ^a   Meng, Xiang Jin ^a  

^a CENTER FOR MOLECULAR MEDICINE AND INFECTIOUS DISEASES   (United States)

^b IOWA STATE UNIVERSITY   (United States)

Author keywords

Capsid protein; Cross protection; Hepatitis E virus (HEV); Pigs; Vaccine

Indexed keywords

AVIAN HEV ORF2 ANTIGEN; GENOTYPE 3 MAMMALIAN HEV; HEPATITIS E ANTIBODY; HEPATITIS E VACCINE; ORF2 VIRUS CAPSID ANTIGEN; RAT HEV ORF2 ANTIGEN; RECOMBINANT PROTEIN; SWINE HEV ORF2 ANTIGEN; UNCLASSIFIED DRUG; VIRUS CAPSID ANTIGEN; VIRUS RNA;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; AUTOPSY; BLOOD LEVEL; CONTROLLED STUDY; CROSS PROTECTION; ESCHERICHIA COLI; EXPERIMENTAL PIG; FECES ANALYSIS; FOWL; GENOTYPE; HEPATITIS E; HEPATITIS E VIRUS; HISTOPATHOLOGY; IMMUNIZATION; LIVER; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEROCONVERSION; SWINE; VIREMIA; VIRUS SHEDDING; VIRUS STRAIN;

ANIMALS; BIRDS; CAPSID PROTEINS; CROSS PROTECTION; DISEASE MODELS, ANIMAL; FECES; GENOTYPE; HEPATITIS ANTIBODIES; HEPATITIS E; HEPATITIS E VIRUS; HISTOCYTOCHEMISTRY; IMMUNOGLOBULIN G; LIVER; RATS; SWINE; VACCINATION; VACCINES, SYNTHETIC; VIRAL HEPATITIS VACCINES; VIREMIA; VIRUS SHEDDING;

EID: 84865803164     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2012.08.013     Document Type: Article

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