Kinetic evidence of a noncatalytic substrate binding site that regulates activity in legionella pneumophila l -serine dehydratase

Biochemistry

Volumn 51, Issue 35, 2012, Pages 6961-6967

  Grant, Gregory A ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL CELLS; CATALYTIC CENTER; CATALYTIC CYCLES; CONFORMATIONAL CHANGE; D-3-PHOSPHOGLYCERATE DEHYDROGENASE; KINETIC EVIDENCE; L-SERINE; LEGIONELLA PNEUMOPHILA; MYCOBACTERIUM TUBERCULOSIS; NON-CATALYTIC; NONCATALYTIC SITES; PRE-STEADY-STATE KINETIC ANALYSIS; SEQUENCE HOMOLOGY; STRUCTURAL HOMOLOGY; SUBSTRATE-BINDING SITES;

CATALYSIS; ENZYMES; RATE CONSTANTS; SUBSTRATES;

AMINO ACIDS;

PHOSPHOGLYCERATE DEHYDROGENASE; SERINE DEHYDRATASE;

ARTICLE; BACTERIAL CELL WALL; BINDING SITE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME REGULATION; LEGIONELLA PNEUMOPHILA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

BINDING SITES; COMPUTER SIMULATION; KINETICS; L-SERINE DEHYDRATASE; LEGIONELLA PNEUMOPHILA; MODELS, BIOLOGICAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PYRUVIC ACID; SERINE; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); LEGIONELLA PNEUMOPHILA; MYCOBACTERIUM TUBERCULOSIS;

EID: 84865795514     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi3008774     Document Type: Article

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