Virotherapy using a novel chimeric oncolytic adenovirus prolongs survival in a human pancreatic cancer xenograft model

Surgery (United States)

Volumn 152, Issue 3, 2012, Pages 441-448

  Chu, Quyen D ^a   Sun, Guang ^a   Pope, Matt ^a   Luraguiz, Natalia ^a   Curiel, David T ^b   Kim, Roger ^a   Li, Benjamin D L ^a   Mathis, J Michael ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CHEMOKINE RECEPTOR CXCR4; GREEN FLUORESCENT PROTEIN; ONCOLYTIC ADENOVIRUS; PHOSPHATE BUFFERED SALINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; ONCOLYTIC VIROTHERAPY; OVERALL SURVIVAL; PANCREAS CANCER; PRIORITY JOURNAL; SURVIVAL TIME; TUMOR VOLUME; TUMOR XENOGRAFT; WILD TYPE;

ADENOCARCINOMA; ANALYSIS OF VARIANCE; ANIMALS; CELL LINE, TUMOR; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; MICE; MICE, SCID; ONCOLYTIC VIROTHERAPY; ONCOLYTIC VIRUSES; PANCREATIC NEOPLASMS; RATS; RECEPTORS, CXCR4; SEROTYPING; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84865794666     PISSN: 00396060     EISSN: 15327361     Source Type: Journal    
DOI: 10.1016/j.surg.2012.05.040     Document Type: Article

References (28)

1. A. Jemal, R. Siegel, J. Xu, and E. Ward Cancer statistics, 2010 CA Cancer J Clin 60 2010 277 300
2. Q.D. Chu, N. Khushalani, M. Javle, H. Douglass, and J. Gibbs Should adjuvant therapy remain standard of care for patients with resected adenocarcinoma of the pancreas? Ann Surg Oncol 10 2003 539 545
3. D. Wong, and W. Korz Translating an antagonist of chemokine receptor CXCR4: from bench to bedside Clin Cancer Res 14 2008 7975 7980
4. D.M. Parkin, F. Bray, J. Ferlay, and P. Pisani Global cancer statistics CA Cancer J Clin 55 2005 74 108
5. A. Ben-Baruch The multifaceted roles of chemokines in malignancy Cancer Metast Rev 25 2006 357 371
6. A. Mueller, B. Homey, and H. Soto Involvement of chemokine receptors in breast cancer metastasis Nature 410 2001 50 56
7. O. Salvucci, A. Bouchard, and A. Baccarelli The role of CXCR4 receptor expression in breast cancer: a large tissue microarray study Breast Cancer Res Treat 97 2006 275 283
8. Q.D. Chu, L. Panu, N. Holm, B. Li, L. Johnson, and S. Zhang High chemokine receptor CXCR4 level in triple negative breast cancer specimens predicts poor clinical outcome J Surg Res 159 2010 689 695
9. A. Ottaniano, R. Franco, and A. Aiello Talamanca Overexpression of both CXC chemokine receptor 4 and vascular endothelial growth factor proteins predicts early distant relapse in stages II-III colorectal cancer patients Clin Cancer Res 12 2006 2795 2803
10. T. Murakami, W. Maki, and A.R. Cardones Expression of CXC chemokine receptor-4 enhances the pulmonary metastatic potential of murine B16 melanoma cells Cancer Res 62 2002 7328 7334
11. T. Wehler, F. Wolfert, and C. Schimanski Strong expression of chemokine receptor CXCR4 by pancreatic cancer correlates with advanced disease Oncol Rep 16 2006 1159 1164
12. J. Short, A. Rivera, and H. Wu Substitution of adenovirus serotype 3 hexon onto a serotype 5 oncolytic adenovirus reduces factor X binding, decreases liver tropism, and improves antitumor efficiency Mol Cancer Ther 9 2010 OF1-9
13. R. Thomas, J. Kim, M. Revelo-Penafiel, R. Angel, D. Dawson, and A. Lowy The chemokine receptor CXCR4 is expressed in pancreatic intraepithelial neoplasia Gut 57 2008 1555 1560
14. M. Stoff-Khalili, A. Rivera, and A. Stoff Combining high selectivity of replication via CXCR4 promoter with fiber chimerism for effective adenoviral oncolysis in breast cancer Int J Cancer 120 2006 935 941
15. E.V. Paster, K.A. Villines, and D.L. Hickman Endpoints for mouse abdominal tumormodels: refinement of current criteria Comp Med 59 2009 234 241
16. V. Krasnykh, I. Dmitriev, and J. Navarro Advanced generation adenoviral vectors possess augmented gene transfer efficiency based upon coxsackie adenovirus receptor-independent cellular entry capacity Cancer Res 60 2000 6784 6787
17. T. Uil, T. Seki, and I. Dmitriev Generation of an adenoviral vector containing an addition of a heterologous ligand to the serotype 3 fiber knob Cancer Gene Ther 10 2003 121 124
18. T. Nishimoto, K. Yoshida, and Y. Miura Oncolytic virus therapy for pancreatic cancer using the adenovirus library displaying random peptides on the fiber knob Gene Ther 16 2009 669 680
19. S. Yang, J. Cody, and A. Rivera Conditionally replicating adenovirus expression TIMP2 for ovarian cancer therapy Clin Cancer Res 17 2011 538 549
20. B. Everts, and H. van der Poel Replication-selective oncolytic viruses in the treatment of cancer Cancer Gene Ther 12 2005 141 161
21. D. Curiel The development of conditionally replicative adenoviruses for cancer therapy Clin Cancer Res 6 2000 3395 3399
22. R. Alemany, C. Balague, and D. Curiel Replicative adenoviruses for cancer therapy Nat Biotechnol 18 2000 723 727
23. M. Stoff-Khalili, A. Stoff, A. Rivera, N. Banerjee, M. Everts, and S. Young Preclinical evaluation of transcriptional targeting strategies for carcinoma of the breast in a tissue slice model system Breast Cancer Research 7 2005 R1141 R1152
24. F. Marchesi, P. Monti, and B. Leone Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4 Cancer Res 64 2004 8420 8427
25. D. Saur, B. Seidler, and G. Schneider CXCR4 expression increases liver and lung metastasis in a mouse model of pancreatic cancer Gastroenterology 129 2005 1237 1250
26. T. Mori, R. Doi, and M. Koizumi CXCR4 antagonist inhibits stromal cell-derived factor 1-induced migration and invasion of human pancreatic cancer Mol Cancer Ther 3 2004 29 37
27. T. Koshiba, R. Hosotani, and Y. Miyamoto Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression Clin Can Res 6 2000 3530 3535
28. J. Spencer, J. Sagartz, W. Wold, and K. Toth New pancreatic carcinoma model for studying oncolytic adenoviruses in the permissive Syrian hamster Cancer Gene Ther 16 2009 912 922