Ciliated adenocarcinomas of the lung: A tumor of non-terminal respiratory unit origin

Modern Pathology

Volumn 25, Issue 9, 2012, Pages 1265-1274

  Park, Won Young ^a   Kim, Mi Hyun ^b   Shin, Dong Hoon ^a,b   Lee, Jung Hee ^a   Choi, Kyung Un ^a   Kim, Jee Yeon ^a   Park, Do Youn ^a   Lee, Chang Hun ^a   Sol, Mee Young ^a  

^a Pusan National University School of Medicine   (South Korea)

^b Pusan National University   (South Korea)

Author keywords

adenocarcinoma; lung; mucous columnar cell change

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; K RAS PROTEIN;

ADULT; BRONCHIOLE; CANCER DIAGNOSIS; CANCER SURGERY; CELL NUCLEUS; CELL STRUCTURE; CILIATED EPITHELIUM; CLARA CELL; COLUMNAR EPITHELIUM; DYSPLASIA; EUKARYOTIC FLAGELLUM; FEMALE; GENE MUTATION; HUMAN; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LOBECTOMY; LUNG ADENOCARCINOMA; LUNG ALVEOLUS CELL; LUNG NON SMALL CELL CANCER; LUNG RESECTION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REVIEW; SMOKING; WEDGE RESECTION;

ADENOCARCINOMA, BRONCHIOLO-ALVEOLAR; BRONCHIOLES; CILIA; EPITHELIAL CELLS; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; METAPLASIA; MIDDLE AGED; MUTATION; NEOPLASM STAGING; PNEUMOCYTES; PROTO-ONCOGENE PROTEINS; RAS PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 84865782585     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2012.76     Document Type: Review

References (21)

1. Stricker TP, Kumar V. Neoplasia. In: Kumar V, Cotran RS, Robbins SL (eds). Robbins Basic Pathology. Saunders: Philadelphia, PA, 2010, pp 325-360.
2. Kohno H, Hiroshima K, Toyozaki T, et al p53 mutation and allelic loss of chromosome 3p, 9p of preneoplastic lesions in patients with nonsmall cell lung carcinoma. Cancer 1999;85:341-347.
3. Mori M, Rao SK, Popper HH, et al Atypical adenomatous hyperplasia of the lung: a probable forerunner in the development of adenocarcinoma of the lung. Mod Pathol 2001;14:72-84.
4. Chapman A, Kerr K. The association between atypical adenomatous hyperplasia and primary lung cancer. Br J Cancer 2000;83:632-636.
5. Mori M, Rao SK, Popper HH, et al Atypical adenomatous hyperplasia of the lung: a probable forerunner in the development of adenocarcinoma of the lung. Mod Pathol 2001;14:72-84.
6. Ullmann R, Bongiovanni M, Halbwedl I, et al Bronchiolar columnar cell dysplasia-genetic analysis of a novel preneoplastic lesion of peripheral lung. Virchows Arch 2003;442:429-446.
7. Pankiewicz W, Minarowski L, liñ ska W, et al Immunohistochemical markers of cancerogenesis in the lung. Folia Histochem Cytobiol 2007;45:65-74.
8. Edwards CW. Pulmonary adenocarcinoma: review of 106 cases and proposed new classification. J Clin Pathol 1987;40:125-135.
9. Stenhouse G, Fyfe N, King G, et al Thyroid transcription factor 1 in pulmonary adenocarcinoma. J Clin Pathol 2004;57:383-387.
10. Shimosato Y. Bronchial gland type carcinomas. In Corrin B (ed). Pathology of Lung Tumours. Churchill Livingstone: Edinburgh, 1997, pp 135-147.
11. Yatabe Y, Mitsudomi T. Epidermal growth factor receptor mutations in lung cancers. Pathol Int 2007; 57:233-244.
12. Yatabe Y, Kosaka T, Takahashi T, et al EGFR mutation is specific for terminal respiratory unit type adenocarcinoma. Am J Surg Pathol 2005;29:633-639.
13. Yatabe Y, Mitsudomi T, Takahashi T. TTF-1 expression in pulmonary adenocarcinomas. Am J Surg Pathol 2002;26:767-773.
14. Ramos SG, Barbosa GH, Tavora FR, et al Bronchioloalveolar carcinoma arising in a congenital pulmonary airway malformation in a child: case report with an update of this association. J Pediatr Surg 2007; 42:E1-E4.
15. Stacher E, Ullmann R, Halbwedl I, et al Atypical goblet cell hyperplasia in congenital cystic adenomatoid malformation as a possible preneoplasia for pulmonary adenocarcinoma in childhood: a genetic analysis. Hum Pathol 2004;35:565-570.
16. Yoo JY, Lee SM, Jung JH, et al Adenocarcinoma arising in type 1 congenital cystic adenomatoid malformation: a case report and review of the literature. Kor J Pathol 2008;42:396-400.
17. Lantuejoul S, Nicholson AG, Sartori G, et al Mucinous cells in type 1 pulmonary congenital cystic adenomatoid malformation as mucinous bronchioloalveolar carcinoma precursors. Am J Surg Pathol 2007;31:961-969.
18. Inamura K, Ninomiya H, Ishikawa Y, et al Is the epidermal growth factor receptor status in lung cancers reflected in clinicopathologic features? Arch Pathol Lab Med 2010;134:66-72.
19. Kerr KM. Pulmonary adenocarcinomas: classification and reporting. Histopathology 2009;54:12-27.
20. Chilosi M, Murer B. Mixed adenocarcinomas of the lung: place in new proposals in classification, mandatory for target therapy. Arch Pathol Lab Med 2010;134:55-65.
21. Jensen-Taubman SM, Steinberg SM, Linnoila RI. Bronchiolization of the alveoli in lung cancer: pathology, patterns of differentiation and oncogene expression. Int J Cancer 1998;75:489-496.