Bronchiolization of the alveoli in lung cancer: Pathology, patterns of differentiation and oncogene expression

International Journal of Cancer

Volumn 75, Issue 4, 1998, Pages 489-496

  Jensen Taubman, Sandra M ^a   Steinberg, Seth M ^a   Linnoila, R Ilona ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR RECEPTOR; LUNG SURFACTANT; MESSENGER RNA; MYC PROTEIN; ONCOPROTEIN; PROTEIN P53;

ARTICLE; BRONCHIOLE; CELL DIFFERENTIATION; CLARA CELL; CLINICAL PROTOCOL; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LUNG ALVEOLUS EPITHELIUM; LUNG NON SMALL CELL CANCER; LUNG RESECTION; MAJOR CLINICAL STUDY; ONCOGENE; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

BRONCHI; CARCINOMA, NON-SMALL-CELL LUNG; CELL DIFFERENTIATION; HUMANS; IMMUNOENZYME TECHNIQUES; KERATINS; LUNG DISEASES; LUNG NEOPLASMS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEINS; PROTEOLIPIDS; PROTO-ONCOGENE PROTEINS; PULMONARY ALVEOLI; PULMONARY SURFACTANT-ASSOCIATED PROTEINS; PULMONARY SURFACTANTS; RECEPTORS, GROWTH FACTOR; UTEROGLOBIN;

EID: 0032498593     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19980209)75:4<489::AID-IJC1>3.0.CO;2-P     Document Type: Article

References (23)

1. BERNARD, A., ROELS, H., LAUWERYS, R., WITTERS, R., GIELENS, C., SOUMILLION, A., VAN DAMME, J. and DE LEY, M., Human urinary protein 1: evidence for identity with the Clara cell protein and occurrence in respiratory tract and urogenital secretions. Clin. chim. Acta, 207, 239-249 (1992).
2. BROERS, J.L.V., VIALLET, J., JENSEN, S.M., PASS, H., TRAVIS, W.D., MINNA, J.D. and LINNOILA, R.I., Expression of c-myc in progenitor cells of the bronchopulmonary epithelium and in a large number of non-small cell lung cancers. Amer. J. respir. Cell mol. Biol., 9, 33-43 (1993).
3. EBINA, M., STEINBERG, S.M., MULSHINE, J.L. and LINNOILA, R.I., Relationship of p53 overexpression and up-regulation of proliferating cell nuclear antigen with the clinical course of non-small cell lung cancer. Cancer Res., 54, 2496-2503 (1994).
4. FRANKLIN, W.A., KENNEDY, T.C., DEMPSEY, E.J. and MILLER, Y.E., Micropapillary squamous metaplasia: a lesion reflecting angiogenesis in bronchial mucosa of smokers. Lung Cancer, 18 (S1), 173 (1997).
5. JENSEN, S.M., JONES, J.E., PASS, H., STEINBERG, S.M. and LINNOILA, R.I., Clara cell 10 kDa protein mRNA in normal and atypical regions of human respiratory epithelium. Int. J. Cancer, 58, 629-637 (1994).
6. JONCKHEERE, A.R., A distribution-free K-sampIe test against ordered alternatives. Biometrika, 41, 133-145 (1954).
7. KERR, K., CAREY, F., KING, G. and LAMB, D., Atypical alveolar hyperplasia: relationship with pulmonary adenocarcinoma, p53, and c-erbB-2 expression. J. Pathol., 174, 249-256 (1994).
8. KITAMURA, H., KAMEDA, Y., NAKAMURA, N., NAKATANI, Y., INAYAMA, Y., IDA, M., NODA, K., OGAWA, N., SHIBAGAKI, T. and KANISAWA, M., Proliferate potential and p53 overexpression in precursor and early stage lesions of bronchioloaiveolar lung carcinoma. Amer. J. Pathol., 146, 876-887 (1995).
9. LINNOILA, R.I., JENSEN, S.M., STEINBERG, S.M., MULSHINE, J.L., EGGLESTON, J.C. and GAZDAR, A.F., Peripheral airway cell marker expression in non-small cell lung carcinoma: association with distinct clinicopathologic features. Amer. J. clin. Pathol., 97, 233-243 (1992).
10. LINNOILA, R.I., PIANTADOSI, S. and RUCKDESCHEL, J.C., Impact of neuroendocrine differentiation in non-small cell lung cancer. Chest, 106, 367S-371S (1994).
11. NETTESHEIM, P. and SZAKAL, M.S., Morphogenesis of alveolar bronchiolization. Lab. Invest., 26, 210-219 (1972).
12. RUCKDESCHEL, J.C., LINNOILA, R.I., MULSHINE, J.L., KIM, K., AISNER, S., GAZDAR, A.F., JENSEN, S.M. and BONOMI, P., The impact of neuroendocrine (NE) and epithelial (EPI) differentiation on response and survival in lung cancer: the ECOG experience. Proc. Amer. Soc. Clin. Oncol., 10, 248 (1991).
13. SCHAAFSMA, H.E. and RAMAEKERS, F.C.S., Cytokeratin subtyping in normal and neoplastic epithelium: basic principles and diagnostic applications. Pathol. Ann., 29 (Pt. 1), 21-62 (1994).
14. SHAW, G.L. and 14 OTHERS, Individualized chemotherapy for patients with non-small cell lung cancer determined by prospective identification of neuroendocrine markers and in vitro drug sensitivity testing. Cancer Res., 53, 5181-5187 (1993).
15. SHI, D., HE, G., CAO, S., PAN, W., ZHANG, H., YU, D. and HUNG, M., Overexpression of the c-erbB-2/neu-encoded p185 protein in primary lung cancer. Mol. Carcinogenesis, 5, 213-218 (1992).
16. SHIMOSATO, Y., Pulmonary neoplasms. In: S.S. Sternberg (ed.), Diagnostic surgical pathology, pp. 785-827, Raven Press, New York (1989).
17. SIEGFRIED, J.M., GUENTERT, P.J. and GAITHER, A.L., Effects of bombesin and gastrin-releasing peptide on human bronchial epithelial cells from a series of donors: individual variation and modulation by bombesin analogs. Anal Record, 236, 241-247 (1993).
18. SIMON, R.H. and PAINE, R., Participation of pulmonary alveolar epithelial cells in lung inflammation. J. Lab. Clin. Med., 126, 108-118 (1995).
19. SLAUGHTER, D.P., SOUTHWICK, H.W. and SMEJKAL, W., "Field cancerization" in oral stratified squamous epithelium. Cancer, 6, 963-968 (1953).
20. SLEBOS, R., CLEMENT, M., BAAS, I., OFFERHAUS, J., ASKIN, F., HRUBAN, H. and WESTRA, N., p53 and p21WAF1/Cip1 in atypical alveolar hyperplasia of the lung. Proc. Amer. Assoc. Cancer Res., 38, 271 (1997).
21. SOZZI, G., MUIZZO, M., TALGLIABUE, E., CALDERONE, C., PILOTTI, L.S., PASTORINO, U., PIEROTTI, M. and DELLA PORTA, G., Cytogenetic abnormalities and overexpression of receptors for growth factors in normal bronchial epithelium and tumor samples of lung cancer patients. Cancer Res., 51, 400-404 (1991).
22. TEN HAVE-OPBROEK, A.A.W., BENFIELD, J.R., VAN KRIEKEN, J.H. and DUKMAN, J.H., The alveolar type II cell is a pluripotential stem cell in the genesis of human adenocarcinomas and squamous cell carcinomas. Histol. Histopathol., 12, 319-336 (1997).
23. WENG, S., TSUCHIYA, E., KASUGA, T. and SUGANO, H., Incidence of atypical bronchioloalveolar cell hyperplasia of the lung: relation to histological subtypes of lung cancer. Virchows Arch. (A), 420, 463-471 (1992).