An integrated approach in the diagnosis of smoking-related interstitial lung diseases

European Respiratory Review

Volumn 21, Issue 125, 2012, Pages 207-217

  Caminati, Antonella ^a   Cavazza, Alberto ^b   Sverzellati, Nicola ^c   Harari, Sergio ^a  

^a IRCCS MULTIMEDICA   (Italy)

^b S MARIA NUOVA HOSPITAL   (Italy)

^c UNIVERSITY OF PARMA   (Italy)

Author keywords

Desquamative interstitial pneumonia; Interstitial lung diseases; Langerhans' cell histiocytosis; Respiratory bronchiolitis; Smoking

Indexed keywords

BOSENTAN; CHLORAMBUCIL; CLADRIBINE; CORTICOSTEROID; CYCLOPHOSPHAMIDE; ETOPOSIDE; METHOTREXATE; VINBLASTINE;

BRONCHIOLITIS; CIGARETTE SMOKING; DISEASE ASSOCIATION; DISEASE SEVERITY; EMPHYSEMA; FIBROSING ALVEOLITIS; GOODPASTURE SYNDROME; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HISTIOCYTOSIS X; HISTOPATHOLOGY; HUMAN; INTERSTITIAL LUNG DISEASE; INTERSTITIAL PNEUMONIA; LOEFFLER PNEUMONIA; LUNG BIOPSY; LUNG HEMORRHAGE; LUNG TRANSPLANTATION; PATHOPHYSIOLOGY; PROGNOSIS; PULMONARY HYPERTENSION; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; RHEUMATOID ARTHRITIS; SMOKING CESSATION;

HUMANS; LUNG; LUNG DISEASES, INTERSTITIAL; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RISK ASSESSMENT; RISK FACTORS; SMOKING; SMOKING CESSATION;

EID: 84865778649     PISSN: 09059180     EISSN: 16000617     Source Type: Journal    
DOI: 10.1183/09059180.00003112     Document Type: Review

References (101)

1. Visscher DW, Myers JL. Bronchiolitis: the pathologist's perspective. Proc Am Thorac Soc 2006; 3: 41-47.
2. Wright JL, Cagle P, Churg A, et al. Diseases of the small airways. Am Rev Respir Dis 1992; 146: 240-262.
3. Shaw RJ, Djukanovic R, Tashkin DP, et al. The role of small airways in lung disease. Respir Med 2002; 96: 67-80.
4. Fraig M, Shreesha U, Savici D, et al. Respiratory bronchiolitis: a clinicopathologic study in current smokers, ex-smokers, and never-smokers. Am J Surg Pathol 2002; 26: 647-653.
5. Myers JL, Veal CF Jr, Shin MS, et al. Respiratory bronchiolitis causing interstitial lung disease: a clinical pathologic study of six cases. Am Rev Respir Dis 1987; 135: 880-884.
6. Moon J, du Bois RM, Colby TV, et al. Clinical significance of respiratory bronchiolitis on open lung biopsy and its relationship to smoking related interstitial lung disease. Thorax 1999; 54: 1009-1014.
7. Heyneman LE, Ward S, Lynch DA, et al. Respiratory bronchiolitis, respiratory bronchiolitis-associated interstitial lung disease, and desquamative interstitial pneumonia: different entities or part of the spectrum of the same disease process? AJR Am J Roentgenol 1999; 173: 1617-1622.
8. Craig PJ, Wells AU, Doffman S, et al. Desquamative interstitial pneumonia, respiratory bronchiolitis and their relationship to smoking. Histopathology 2004; 45: 275-282.
9. Mang CM, Grosse C, Schmid K, et al. What every radiologist should know about idiopathic interstitial pneumonias. Radiographics 2007; 27: 595-615.
10. Myers JL, Katzenstein AL. Beyond a consensus classification for idiopathic interstitial pneumonias: progress and controversies. Histopathology 2009; 54: 90-103.
11. Yousem S, Colby T, Gaensler E. Respiratory bronchiolitis-associated interstitial lung disease and its relationship to desquamative interstitial pneumonia. Mayo Clin Proc 1989; 64: 1373-1380.
12. Elkin SL, Nicholson AG, du Bois RM. Desquamative interstitial pneumonia and respiratory bronchiolitis-associated interstitial lung disease. Semin Respir Crit Care Med 2001; 22: 387-398.
13. Kawabata Y, Takemura T, Hebisawa A, et al. Eosinophilia in bronchoalveolar lavage fluid and architectural destruction are features of desquamative interstitial pneumonia. Histopathology 2008; 52: 194-202.
14. Portnoy J, Veraldi KL, Schwarz MI, et al. Respiratory bronchiolitisinterstitial lung disease: long-term outcome. Chest 2007; 131: 664-671.
15. Ryu JH, Myers JL, Capizzi SA, et al. Desquamative interstitial pneumonia and respiratory bronchiolitis-associated interstitial lung disease. Chest 2005; 127: 178-184.
16. Yogo Y, Oyamada Y, Ishii M, et al. A case of acute exacerbation of desquamative interstitial pneumonia after video-assisted thoracoscopic surgery (VATS). J Japan Resp Soc 2003; 41: 386-391.
17. Sánchez Varilla JM, Vázquez Martin M, Garcia Dante H, et al. Exacerbacion aguda de un caso de neumonitis intersticial descamativa tras biopsia pulmonar por videotorascoscopia [Acute exacerbation of desquamative interstitial pneumonia after thoracoscopy lung biopsy]. Ann Med Intern 2005; 22: 604-605.
18. Tazelaar HD, Wright JL, Churg A. Desquamative interstitial pneumonia. Histopathology 2011; 58: 509-516.
19. Demedts M, Costabel U. ATS/ERS international multidisciplinary consensus classification of the idiopathic interstitial pneumonias. Eur Respir J 2002; 19: 794-796.
20. Ishii H, Iwata A, Sakamoto N, et al. Desquamative interstitial pneumonia (DIP) in a patient with rheumatoid arthritis: is DIP associated with autoimmune disorders? Intern Med 2009; 48: 827-830.
21. Beasley MB. Smoking-related small airway disease-a review and update. Adv Anat Pathol 2010; 17: 270-276.
22. Pappas K. Bronchiolitis and bronchial disorders in interstitial lung disease. Curr Opin Pulm Med 2011; 17: 316-324.
23. Kambouchner M, Basset F, Marchal J, et al. Three-dimensional characterization of pathologic lesions in pulmonary Langerhans cell histiocytosis. Am J Respir Crit Care Med 2002; 166: 1483-1490.
24. Yousem SA. Respiratory bronchiolitis-associated interstitial lung disease with fibrosis is a lesion distinct from fibrotic nonspecific interstitial pneumonia: a proposal. Mod Pathol 2006; 19: 1474-1479.
25. Hansell DM, Nicholson AG. Smoking-related diffuse parenchymal lung disease: HRCT-pathologic correlation. Semin Respir Crit Care Med 2003; 24: 377-392.
26. Marten K, Milne D, Antoniou KM, et al. Non-specific interstitial pneumonia in cigarette smokers; a CT study. Eur Radiol 2009; 19: 1679-1685.
27. Galvin JR, Franks TJ. Smoking-related lung disease. J Thorac Imaging 2009; 24: 274-284.
28. Shorr AF, Scoville SL, Cersovsky SB, et al. Acute eosinophilic pneumonia among US military personnel deployed in or near Iraq. JAMA 2004; 292: 2997-3005.
29. Cottin V, Nunes H, Brillet PY, et al. Combined pulmonary fibrosis and emphysema: a distinct under recognized entity. Eur Respir J 2005; 26: 586-593.
30. Cottin V, Le Pavec J, Prévot G, et al. Pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema syndrome. Eur Respir J 2010; 35: 105-111.
31. Balbi B, Cottin V, Singh S, et al. Smoking-related lung diseases: a clinical perspective. Eur Respir J 2010; 35: 231-233.
32. Harari S, Caminati A. Update on diffuse parenchymal lung disease. Eur Respir Rev 2010; 19: 97-108.
33. Myers JL. Respiratory bronchiolitis with interstitial lung disease. Semin Respir Med 1992; 13: 134-139.
34. Caminati A, Graziano P, Sverzellati N, et al. Smoking-related interstitial lung diseases. Pathologica 2010; 102: 525-536.
35. Gill A. Bong lung: regular smokers of cannabis show relatively distinctive histologic changes that predispose to pneumothorax. Am J Surg Pathol 2005; 29: 980-982.
36. Remy-Jardin M, Remy J, Gosselin B, et al. Lung parenchymal changes secondary to cigarette smoking: pathologic-CT correlations. Radiology 1993; 186: 643-651.
37. Remy-Jardin M, Remy J, Boulenguez C, et al. Morphologic effects of cigarette smoking on airways and pulmonary parenchyma in healthy adult volunteers: CT evaluation and correlation with pulmonary function tests. Radiology 1993; 186: 107-115.
38. Hansell DM. Small airways diseases: detection and insights with computed tomography. Eur Respir J 2001; 17: 1294-1313.
39. Hansell DM. Thin-section CT of the lungs: the Hinterland of normal. Radiology 2010; 256: 695-711.
40. Wells AU, Nicholson AG, Hansell DM. Challenges in pulmonary fibrosis. 4: smoking-induced diffuse interstitial lung diseases. Thorax 2007; 62: 904-910.
41. Churg A, Muller NL, Wright JL. Respiratory bronchiolitis/ interstitial lung disease. Fibrosis, pulmonary functions, and evolving concepts. Arch Pathol Lab Med 2010; 134: 27-32.
42. Vassallo R, Jensen EA, Colby TV, et al. The overlap between respiratory bronchiolitis and desquamative interstitial pneumonia in pulmonary Langerhans cell histiocytosis. High-resolution CT, histologic, and functional correlations. Chest 2003; 124: 1199-1205.
43. Kawabata Y, Hoshi E, Murai K, et al. Smoking-related changes in the background lung of specimens resected for lung cancer: a semiquantitative study with correlation to postoperative course. Histopathology 2008; 53: 707-714.
44. Washko GR, Hunninghake GM, Fernandez IE, et al. Lung volumes and emphysema in smokers with interstitial lung abnormalities. N Engl J Med 2011; 364: 897-906.
45. Sverzellati N, Guerci L, Randi G, et al. Interstitial lung diseases in a lung cancer screening trial. Eur Respir J 2011; 38: 392-400.
46. Copley SJ, Wells AU, Hawtin KE, et al. Lung morphology in the elderly: comparative CT study of subjects over 75 years old versus those under 55 years old. Radiology 2009; 251: 566-573.
47. Snider G, Kleinerman J, Thurlbeck W, et al. The definition of emphysema. Report of a National Heart, Lung and Blood Institute division of lung diseases workshop. Am Rev Respir Dis 1985; 132: 182-185.
48. Bellomi M, Rampinelli C, Veronesi G, et al. Evolution of emphysema in relation to smoking. Eur Radiol 2010; 20: 286-292.
49. Wright JL, Tazelaar HD, Churg A. Fibrosis with emphysema. Histopathology 2011; 58: 517-524.
50. Katzenstein AL. Smoking-related interstitial fibrosis (SRIF), pathogenesis and treatment of usual interstitial pneumonia (UIP), and transbronchial biopsy in UIP. Mod Pathol 2012; 25: Suppl. 1, S68-S78.
51. Katzenstein ALA, Mukhopadhyay S, Zanardi C, et al. Clinically occult interstitial fibrosis in smokers: classification and significance of a surprisingly common finding in lobectomy specimens. Hum Pathol 2010; 41: 316-325.
52. Akira M, Inoue Y, Kitaichi M, et al. Usual interstitial pneumonia and nonspecific interstitial pneumonia with and without concurrent emphysema: thin-section CT findings. Radiology 2009; 251: 271-279.
53. Sholl LM, Hornick JL, Pinkus JL, et al. Immunohistochemical analysis of Langerin in Langerhans cell histiocytosis and pulmonary inflammatory and infectious diseases. Am J Surg Pathol 2007; 31: 947-952.
54. Colby TV, Lombard C. Histiocytosis X in the lung. Hum Pathol 1983; 14: 847-856.
55. Cavazza A, Rossi G, Barbareschi M, et al. I macrofagi nelle malattie interstiziali del polmone: loro utilità diagnostic [Diagnostic utility of macrophages in interstitial lung disease]. Pathologica 2006; 98: 211-223.
56. Soler P, Bergeron A, Kambouchner M, et al. Is high-resolution computed tomography a reliable tool to predict the histopathological activity of pulmonary Langerhans cell histiocytosis? Am J Respir Crit Care Med 2000; 162: 264-270.
57. Koyama M, Johkoh T, Honda O, et al. Chronic cystic lung disease: diagnostic accuracy of high-resolution CT in 92 patients. AJR Am J Roentgenol 2003; 180: 827-835.
58. Kim HJ, Lee KS, Johkoh T, et al. Pulmonary Langerhans cell histiocytosis in adults: high-resolution CT-pathology comparisons and evolutional changes at CT. Eur Radiol 2011; 21: 1406-1415.
59. Hartmann TE, Primack SL, Kang EY, et al. Disease progression in usual interstitial pneumonia compared with desquamative interstitial pneumonia. Chest 1996; 110: 378-382.
60. Hidalgo A, Franquet T, Gimenez A, et al. Smoking-related interstitial lung diseases: radiologic-pathologic correlation. Eur Radiol 2006; 16: 2463-2470.
61. Flaherty KR, Travis WD, Colby TV, et al. Histologic variability in usual and nonspecific interstitial pneumonias. Am J Respir Crit Care Med 2001; 164: 1722-1727.
62. Gaensler EA, Carrington CB. Open biopsy for chronic diffuse infiltrative lung disease: clinical, roentgenographic, and physiological correlations in 502 patients. Ann Thorac Surg 1980; 30: 411-426.
63. Vassallo R, Ryu JH, Colby TV, et al. Pulmonary Langerhans cell histiocytosis. N Eng J Med 2000; 342: 1969-1978.
64. Soler P, Kambouchner M, Valeyre D, et al. Pulmonary Langerhans' cell granulomatosis (histiocytosis X). Annu Rev Med 1992; 43: 105-115.
65. Travis WD, Borok Z, Roum JH, et al. Pulmonary Langerhans cell granulomatosis (histiocytosis X): a clinicopathologic study of 48 cases. Am J Surg Pathol 1993; 17: 971-986.
66. Tazi A, Soler P, Hance AJ. Adult pulmonary Langerhans' cell histiocytosis. Thorax 2000; 55: 405-416.
67. Rao RN, Goodman LR, Tomashefski JF. Smoking-related interstitial lung disease. Ann Diagn Pathol 2008; 12: 445-457.
68. Soler P, Tazi A, Hance AJ. Pulmonary Langerhans cell granulomatosis. Curr Opin Pulm Med 1995; 1: 406-416.
69. Brabencova E, Tazi A, Lorenzato M, et al. Langerhans cells in Langerhans cell granulomatosis are not actively proliferating cells. Am J Pathol 1998; 152: 1143-1149.
70. Marchal J, Kambouchner M, Tazi A, et al. Expression of apoptosisregulatory proteins in lesions of pulmonary Langerhans cell histiocytosis. Histopathology 2004; 45: 20-28.
71. Senechal B, Elain G, Jeziorski E, et al. Expansion of regulatory T cells in patients with Langerhans cell histiocytosis. PLoS Medicine 2007; 4: 1374-1384.
72. Suri HS, Yi ES, Nowakowski GS, et al. Pulmonary Langerhans cell histiocytosis. Orphanet J Rare Dis 2012; 7: 16.
73. Badalian-Very G, Vergilio JA, Degar BA, et al. Recurrent BRAF mutations in Langerhans cell histiocytosis. Blood 2010; 116: 1919-1923.
74. Yousem SA, Colby TV, Chen YY, et al. Pulmonary Langerhans' cell histiocytosis: molecular analysis of clonality. Am J Surg Pathol 2001; 25: 630-636.
75. Schonfeld N, Frank W, Wenig S, et al. Clinical and radiologic features, lung function and therapeutic results in histiocytosis X. Respiration 1993; 60: 38-44.
76. Paciocco G, Uslenghi E, Bianchi A, et al. Diffuse cystic lung diseases: correlation between radiologic and functional status. Chest 2004; 125: 135-142.
77. Tazi A, Marc K, Dominique S, et al. Serial CT and lung function testing in pulmonary Langerhans cell histiocytosis. Eur Respir J 2012; [Epub ahead of print DOI: 10.1183/09031936.00210711].
78. Lacronique J, Roth C, Battesti JP, et al. Chest radiological features of pulmonary histiocytosis X: a report based on 50 adult cases. Thorax 1982; 32: 104-107.
79. Fartoukh M, Humbert M, Capron F, et al. Severe pulmonary hypertension in histiocytosis X. Am J Respir Crit Care Med 2000; 161: 216-223.
80. Harari S, Brenot F, Barberis M, et al. Advanced pulmonary histiocytosis X is associated with severe pulmonary hypertension. Chest 1997; 111: 1142-1144.
81. Lombard CM, Medeiros J, Colby TV. Pulmonary histiocytosis X and carcinoma. Arch Pathol Lab Med 1987; 111: 339-341.
82. Tomashefski JF, Khiyami A, Kleinerman J. Neoplasms associated with pulmonary eosinophilic granuloma. Arch Pathol Lab Med 1991; 115: 499-506.
83. American Thoracic Society, European Respiratory Society. American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias. Am J Respir Crit Care Med 2002; 165: 277-304.
84. Caminati A, Harari S. Smoking-related interstitial pneumonias and pulmonary Langerhans cell histiocytosis. Proc Am Thorac Soc 2006; 3: 299-306.
85. Torre O, Harari S. The diagnosis of cystic lung diseases: a role for bronchoalveolar lavage and transbronchial biopsy? Respir Med 2010; 104: Suppl. 1, S81-S85.
86. Housini I, Tomashefski JF Jr, Cohen A, et al. Transbronchial biopsy in patients with pulmonary eosinophilic granuloma. Comparison with findings on open lung biopsy. Arch Pathol Lab Med 1994; 118: 523-530.
87. Rao RN, Chang CC, Tomashefski JF Jr. Lymphocyte subpopulations and non-Langerhans' cell monocytoid cells in pulmonary Langerhans cell histiocytosis. Pathol Res Pract 2008; 208: 315-322.
88. Ryu JH, Colby TV, Hartman TE, et al. Smoking-related interstitial lung diseases: a concise review. Eur Respir J 2001; 17: 122-132.
89. Marten K, Hansell DM. Imaging of macrophage-related lung diseases. Eur Radiol 2005; 15: 727-741.
90. Verleden GM, Sels F, Van Raemdonck D, et al. Possible recurrence of desquamative interstitial pneumonitis in a single lung transplant recipient. Eur Respir J 1998; 11: 971-974.
91. Von Essen S, West W, Sitorius M, et al. Complete resolution of roentgenographic changes in a patient with pulmonary histiocytosis X. Chest 1990; 98: 765-767.
92. Mogulkuc N, Veral A, Bishop PW, et al. Pulmonary Langerhans' cell histiocytosis: radiologic resolution following smoking cessation. Chest 1999; 115: 1452-1455.
93. Chaowalit N, Pellikka P, Decker P, et al. Echocardiographic and clinical characteristics of pulmonary hypertension complicating pulmonary Langerhans cell histiocytosis. Mayo Clin Proc 2004; 79: 1269-1275.
94. Lazor R, Etienne-Mastroianni B, Khouatra C, et al. Progressive diffuse pulmonary Langerhans cell histiocytosis improbe by cladribine chemotherapy. Thorax 2009; 64: 274-275.
95. Dauriat G, Mal H, Thabut G, et al. Lung transplantation for pulmonary Langerhans' cell histicytosis: a multicenter analysis. Transplantation 2006; 81: 746-750.
96. Vassallo R, Ryu JH, Schroeder DR, et al. Clinical outcomes of pulmonary Langerhans cell histiocytosis in adults. N Engl J Med 2002; 346: 484-490.
97. Harari S, Caminati A. Pulmonary Langerhans cell histiocytosis. Eur Respir Monogr 2009; 46: 155-175.
98. Kiakouama L, Cottin V, Etienne-Mastroianni B, et al. Severe pulmonary hypertension in histiocytosis X: long-term improvement with bosentan. Eur Respir J 2010; 36: 202-211.
99. Le Pavec J, Lorillon G, Jais X, et al. Pulmonary Langerhans cell histiocytosis associated pulmonary hypertension: clinical characteristics and impact of pulmonary arterial hypertension therapies. Chest 2012 [Epub ahead of print DOI: 10.1378/chest.11-2490].
100. Krajicek BJ, Ryu JH, Hartman TE, et al. Abnormal fluorodeoxyglucose PET in pulmonary Langerhans cell histiocytosis. Chest 2009; 135: 1542-1549.
101. Szturz P, Rehak Z, Koukalova R, et al. Measuring diffuse metabolic activity on FDG-PET/TC: new method for evaluating Langerhans cell histiocytosis activity in pulmonary parenchyma. Nucl Med Biol 2012; 39: 429-436.