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Volumn 55, Issue , 2012, Pages 125-136

Synthesis and in vitro antibacterial activity of gemifloxacin derivatives containing a substituted benzyloxime moiety

Author keywords

Antibacterial activity; Gemifloxacin derivatives; Synthesis

Indexed keywords

7 [ 3 AMINOMETHYL 4 ( 2' CHLORO 3',4' DIMETHOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 2',3' DIMETHOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 2',3',4' TRIMETHOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 2',4' DIMETHOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 2',5' DIMETHOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 2',6' DIMETHOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 3',4' DIMETHOXY 2' NITROBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 3',4' DIMETHOXY 6' FLUOROBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 3',4' DIMETHOXY 6' NITROBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 3',4' DIMETHOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 3',4' ETHYLENEDIOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 3',4' METHYLENEDIOXY 6' NITROBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 3',4' METHYLENEDIOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 3',4',5' TRIMETHOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 4' BENZYLOXY 3' METHOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 4' BENZYLOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 4' METHOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 5' CHLORO 3',4' DIMETHOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 6' BROMO 3',4' DIMETHOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 ( 6' CHLORO 3',4' METHYLENEDIOXYBENZYLOXYIMINO)PYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; 7 [ 3 AMINOMETHYL 4 BENZYLOXYIMINOPYRROLIDIN 1 YL] 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 4 OXO 1,8 NAPHTHYRIDIN 3 CARBOXYLIC ACID DIMESYLATE; ANTIBIOTIC AGENT; BENZYLOXIME; GEMIFLOXACIN; GEMIFLOXACIN DERIVATIVE; LEVOFLOXACIN; MOXIFLOXACIN; OXIME DERIVATIVE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG; ANTIINFECTIVE AGENT; NAPHTHYRIDINE DERIVATIVE; OXIME; QUINOLONE DERIVATIVE;

EID: 84865771391     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.07.010     Document Type: Article
Times cited : (55)

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