α1-acid glycoprotein up-regulates CD163 via TLR4/CD14 protein pathway: Possible protection against hemolysis-induced oxidative stress

Journal of Biological Chemistry

Volumn 287, Issue 36, 2012, Pages 30688-30700

  Komori, Hisakazu ^a,b   Watanabe, Hiroshi ^a   Shuto, Tsuyoshi ^a   Kodama, Azusa ^a   Maeda, Hitoshi ^a   Watanabe, Kenji ^a   Kai, Hirofumi ^a   Otagiri, Masaki ^a,c   Maruyama, Toru ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

^c SOJO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PHASE PROTEINS; ACUTE-PHASE RESPONSE; ANTI-INFLAMMATORIES; ANTITRYPSIN; C-REACTIVE PROTEINS; CONCENTRATION-DEPENDENT; CRITICAL FACTORS; EXTRACELLULAR; IMMUNE RECEPTORS; IN-VIVO; INFLAMMATORY CONDITIONS; MOLECULAR MECHANISM; PERIPHERAL BLOOD MONONUCLEAR CELLS; PHYSIOLOGICAL CONCENTRATIONS; POSSIBLE PROTECTIONS; PROTEIN PATHWAYS; SCAVENGER RECEPTOR; SERUM CONCENTRATION; TISSUE DAMAGE; TOLL-LIKE RECEPTOR 4;

ENZYME ACTIVITY; GLYCOPROTEINS; INTERFERONS; MACROPHAGES; OXIDATIVE STRESS; PHYSIOLOGICAL MODELS; TISSUE;

BLOOD;

ALPHA 1 ANTITRYPSIN; C REACTIVE PROTEIN; CD14 ANTIGEN; CD163 ANTIGEN; HAPTOGLOBIN; HEMOGLOBIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; OROSOMUCOID; PHENYLHYDRAZINE; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 4;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HEMOLYSIS; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; NONHUMAN; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD14; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; C-REACTIVE PROTEIN; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; HAPTOGLOBINS; HEMOGLOBINS; HEMOLYSIS; HUMANS; INTERLEUKIN-10; INTERLEUKIN-6; MACROPHAGES; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; MICE; NF-KAPPA B; OROSOMUCOID; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, CELL SURFACE; TOLL-LIKE RECEPTOR 4; UP-REGULATION;

BACTERIA (MICROORGANISMS); MUS;

EID: 84865749056     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.353771     Document Type: Article

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