Identification of CD14 residues involved in specific lipopolysaccharide recognition

Infection and Immunity

Volumn 65, Issue 1, 1997, Pages 293-297

  Shapiro, Robert A ^a   Cunningham, Mark D ^a   Ratcliffe, Kent ^a   Seachord, Carrie ^a   Blake, James ^a   Bajorath, Jürgen ^a   Aruffo, Alejandro ^a   Darveau, Richard P ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD14 ANTIGEN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1;

AMINO TERMINAL SEQUENCE; ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; INFLAMMATION; LIGAND BINDING; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

EID: 0031025738     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.1.293-297.1997     Document Type: Article

References (27)

1. Cunningham, M. D., C. Seachord, K. Katcliffe, B. Bainbridge, A. Aruffo, and R. P. Darveau. 1996. Helicobacter pylori and Porphyromonas gingivalis lipopolysaccharides are poorly transferred to recombinant soluble CD14. Infect. Immun. 64:3601-3608.
2. Darveau, R. P., M. D. Cunningham, T. Bailey, C. Seachord, K. Ratcliffe, B. Bainbridge, M. Dietsch, R. C. Page, and A. Aruffo. 1995. Ability of bacteria associated with chronic inflammatory disease to stimulate E-selectin expression and promote neutrophil adhesion. Infect. Immun. 63:1311-1317.
3. Delude, R. L., R. Savedra, Jr., H. Zhao, R. Thieringer, S. Yamamoto, M. J. Fenton, and D. T. Golenbock. 1995. CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognition. Proc. Natl. Acad. Sci. USA 92:9288-9292.
4. Ferrero, E., C.-L. Hsieh, U. Francke, and W. S. M. Goyert. 1990. CD14 is a member of the family of leucine-rich proteins and is encoded by a gene syntenic with multiple receptor genes. J. Immunol. 145:331-336.
5. Forman, D., D. G. Newell, F. Fullerton, J. W. Yarnell, A. R. Stacey, N. Wald, and F. Sitas. 1991. Association between infection with Helicobacter pylori and risk of gastric cancer: evidence from a prospective investigation. Br. Med. J. 302:1302-1305.
6. Frey, E. A., D. S. Miller, T. G. Jahr, A. Sundan, V. Bazil, T. Espevik, B. B. Finlay, and S. D. Wright. 1992. Soluble CD14 participates in the response of cells to lipopolysaccharide. J. Exp. Med. 176:1665-1671.
7. Gausepohl, H., C. Boulin, M. Kraft, and A. W. Frank. 1992. Automated multiple peptide synthesis. Pept. Res. 5:315-320.
8. Haziot, A., E. Ferrero, F. Kontgen, N. Hijiya, S. Yamamoto, J. Silver, C. L. Stewart, and S. M. Goyert. 1996. Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice. Immunity 4:407-414.
9. Hollenbaugh, D., and A. Aruffo. 1994. Construction of immunoglobulin fusion proteins, p. 10.19.1-10.19.11. In J. F. Coligan, A. M. Kruisbeek, D. H. Marqulies, E. M. Shevach, and W. Strober (ed.), Current protocols in immunology. John Wiley & Sons, Inc., New York, N.Y.
10. Hollenbaugh, D., L. S. Grosmaire, C. D. Kullas, N. J. Chalupny, S. Braesch-Andersen, R. J. Nolle, I. Stamenkovic, J. A. Ledbetter, and A. Aruffo. 1992. The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co-stimulatory activity. EMBO J. 11:4313-4321.
11. Holt, S. C, J. Ebersole, J. Felton, M. Brunsvold, and K. S. Kornman. 1988. Implantation of Bacteroides gingivalis in nonhuman primates initiates progression of periodontitis. Science 239:55-57.
12. Janeway, C. A., Jr. 1992. The immune system evolved to discriminate infectious nonself from noninfectious self. Immunol. Today 13:11-16.
13. Juan, T. S.-C, E. Hailman, M. J. Kelley, L. A. Busse, E. Davy, C. J. Empig, L. O. Narhi, S. D. Wright, and H. S. Lichenstein. 1995. Identification of a lipopolysaccharide binding domain in CD14 between amino acids 57 and 64. J. Biol. Chem. 270:5219-5224.
14. Juan, T. S.-C., M. J. Kelley, D. A. Johnson, L. A. Busse, E. Hailman, S. D. Wright, and H. S. Lichenstein. 1995. Soluble CD14 truncated at amino acid 152 binds lipopolysaccharide (LPS) and enables cellular response to LPS. J. Biol. Chem. 270:1382-1387.
15. Kusunoki, T., E. Hailman, T. S.-C. Juan, H. S. Lichenstein, and S. D. Wright. 1995. Molecules from Staphylococcus aureus that bind CD14 and stimulate innate immune responses. J. Exp. Med. 182:1673-1682.
16. McGinley, M. D., L. O. Narhi, M. J. Kelley, E. Davy, J. Robinson, M. F. Rohde, S. D. Wright, and H. S. Lichenstein. 1995. CD14: physical properties and identification of an exposed site that is protected by lipopolysaccharide. J. Biol. Chem. 270:5213-5218.
17. Ogawa, T. 1993. Chemical structure of lipid A from Porphyromonas (Bacteroides) gingivalis lipopolysaccharide. FEBS Lett. 332:197-201.
18. Ogawa, T., H. Uchida, and K. Amino. 1994. Immunobiological activities of chemically defined lipid A from lipopolysaccharides of Porphyromonas gingivalis. Microbiology 140:1209-1216.
19. Pugin, J., D. Heumann, A. Tomasz, V. V. Kravchenko, Y. Akamatsu, M. Nishijima, M. P. Glauser, P. S. Tobias, and R. J. Ulevitch. 1994. CD14 is a pattern recognition receptor. Immunity 1:509-516.
20. Pugin, J., C.-C. Schurer-Maly, D. Leturcq, A. Moriarty, R. J. Ulevitch, and P. S. Tobias. 1993. Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14. Proc. Natl. Acad. Sci. USA 90:2744-2748.
21. Raetz, C. R. H. 1993. Bacterial endotoxins: extraordinary lipids that activate eucaryotic signal transduction. J. Bacteriol. 175:5745-5753.
22. Shapira, L., S. Takashiba, S. Amar, and T. E. Van Dyke. 1994. Porphyromonas gingivalis lipopolysaccharide stimulation of human monoeytes: dependence on serum and CD14 receptor. Oral Microbiol. Immunol. 9:112-117.
23. Tobias, P. S., K. Soldau, J. A. Gegner, D. Mintz, and R. J. Ulevitch. 1995. Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14. J. Biol. Chem. 270:10482-10488.
24. Ulevitch, R. J., and P. S. Tobias. 1995. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. 13:437-457.
25. Virivakosol, S., and T. N. Kirkland. 1995. A region of human CD14 required for lipopolysaccharide binding. J. Biol. Chem. 270:361-368.
26. Wright, S. D. 1995. CD14 and innate recognition of bacteria. J. Immunol. 155:6-8.
27. Yu, B., and S. D. Wright. 1996. Catalytic properties of lipopolysaccharide (LPS) binding protein. J. Biol. Chem. 271:4100-4105.