The OPCML tumor suppressor functions as a cell surface repressor-adaptor, negatively regulating receptor tyrosine kinases in epithelial ovarian cancer

Cancer Discovery

Volumn 2, Issue 2, 2012, Pages 156-171

  McKie, Arthur B ^a   Vaughan, Sebastian ^a   Zanini, Elisa ^a   Okon, Imoh S ^a   Louis, Louay ^a   de Sousa, Camila ^a   Greene, Mark I ^c   Wang, Qiang ^c   Agarwal, Roshan ^a   Shaposhnikov, Dmitry ^a   Wong, Joshua L C ^a   Gungor, Hatice ^a   Janczar, Szymon ^a   El Bahrawy, Mona ^b   Lam, Eric W F ^a   Chayen, Naomi E ^b   Gabra, Hani ^a  

^a Ovarian Cancer Action Research Centre   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CAVEOLIN 1; CELL ADHESION MOLECULE; EARLY ENDOSOME ANTIGEN 1; EPHRIN RECEPTOR A2; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 4; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 3; OPIOID BINDING PROTEIN CELL ADHESION MOLECULE; POLYUBIQUITIN; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL INCLUSION; CELL PROLIFERATION; COMPUTER MODEL; CONTROLLED STUDY; DOWN REGULATION; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; OVARY CARCINOMA; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TUMOR GROWTH; UBIQUITINATION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CELL ADHESION MOLECULES; CELL GROWTH PROCESSES; CELL LINE, TUMOR; FEMALE; GENES, TUMOR SUPPRESSOR; GPI-LINKED PROTEINS; HUMANS; MICE; NEOPLASM TRANSPLANTATION; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; RECEPTOR PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 84865746086     PISSN: 21598274     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-11-0256     Document Type: Article

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