Structures of lysenin reveal a shared evolutionary origin for pore-forming proteins and its mode of sphingomyelin recognition

Structure

Volumn 20, Issue 9, 2012, Pages 1498-1507

  De Colibus, Luigi ^a   Sonnen, Andreas F P ^a,c,g   Morris, Keith J ^a   Siebert, C Alistair ^a   Abrusci, Patrizia ^b   Plitzko, Jürgen ^c   Hodnik, Vesna ^d   Leippe, Matthias ^e   Volpi, Emanuela ^a   Anderluh, Gregor ^d,f   Gilbert, Robert J C ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^d UNIVERSITY OF LJUBLJANA   (Slovenia)

^e UNIVERSITY OF KIEL   (Germany)

^f NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

^g UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LYSENIN; PHOSPHORYLCHOLINE; PORE FORMING CYTOTOXIC PROTEIN; SPHINGOMYELIN; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; CELL VIABILITY; CHANNEL GATING; CRYSTAL STRUCTURE; EISENIA FETIDA; INNATE IMMUNITY; LIPID ANALYSIS; MOLECULAR RECOGNITION; PARASITE IMMUNITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CRYSTALLOGRAPHY, X-RAY; EVOLUTION, MOLECULAR; HUMANS; JURKAT CELLS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OLIGOCHAETA; PHOSPHORYLCHOLINE; PORE FORMING CYTOTOXIC PROTEINS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; SPHINGOMYELINS; TOXINS, BIOLOGICAL;

EISENIA FETIDA; EUKARYOTA; PROKARYOTA;

EID: 84865730019     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2012.06.011     Document Type: Article

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