-
1
-
-
0027476046
-
Synergy between Ca2+ and protein kinase C is the major factor in determining the level of secretion from human platelets
-
Walker TR, Watson SP. Synergy between Ca2+ and protein kinase C is the major factor in determining the level of secretion from human platelets. Biochem J 1993; 289(Pt 1): 277-82.
-
(1993)
Biochem J
, vol.289
, Issue.PART 1
, pp. 277-282
-
-
Walker, T.R.1
Watson, S.P.2
-
2
-
-
0036905073
-
Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation
-
10.1042/BJ20020226. BJ20020226 [pii].
-
Quinton TM, Kim S, Dangelmaier C, Dorsam RT, Jin J, Daniel JL, Kunapuli SP. Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation. Biochem J 2002; 368: 535-43. 10.1042/BJ20020226. BJ20020226 [pii].
-
(2002)
Biochem J
, vol.368
, pp. 535-543
-
-
Quinton, T.M.1
Kim, S.2
Dangelmaier, C.3
Dorsam, R.T.4
Jin, J.5
Daniel, J.L.6
Kunapuli, S.P.7
-
3
-
-
0032828089
-
Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors
-
Paul BZ, Jin J, Kunapuli SP. Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors. J Biol Chem 1999; 274: 29108-14.
-
(1999)
J Biol Chem
, vol.274
, pp. 29108-29114
-
-
Paul, B.Z.1
Jin, J.2
Kunapuli, S.P.3
-
4
-
-
1642535447
-
Differential role of protein kinase C delta isoform in agonist-induced dense granule secretion in human platelets
-
10.1074/jbc.M306960200. M306960200 [pii].
-
Murugappan S, Tuluc F, Dorsam RT, Shankar H, Kunapuli SP. Differential role of protein kinase C delta isoform in agonist-induced dense granule secretion in human platelets. J Biol Chem 2004; 279: 2360-7. 10.1074/jbc.M306960200. M306960200 [pii].
-
(2004)
J Biol Chem
, vol.279
, pp. 2360-2367
-
-
Murugappan, S.1
Tuluc, F.2
Dorsam, R.T.3
Shankar, H.4
Kunapuli, S.P.5
-
5
-
-
12844270522
-
Regulation of outside-in signaling in platelets by integrin-associated protein kinase C beta
-
M410229200 [pii]. 10.1074/jbc.M410229200.
-
Buensuceso CS, Obergfell A, Soriani A, Eto K, Kiosses WB, Arias-Salgado EG, Kawakami T, Shattil SJ. Regulation of outside-in signaling in platelets by integrin-associated protein kinase C beta. J Biol Chem 2005; 280: 644-53. M410229200 [pii]. 10.1074/jbc.M410229200.
-
(2005)
J Biol Chem
, vol.280
, pp. 644-653
-
-
Buensuceso, C.S.1
Obergfell, A.2
Soriani, A.3
Eto, K.4
Kiosses, W.B.5
Arias-Salgado, E.G.6
Kawakami, T.7
Shattil, S.J.8
-
6
-
-
57049189797
-
Differential roles of the PKC novel isoforms, PKCdelta and PKCepsilon, in mouse and human platelets
-
10.1371/journal.pone.0003793
-
Pears CJ, Thornber K, Auger JM, Hughes CE, Grygielska B, Protty MB, Pearce AC, Watson SP. Differential roles of the PKC novel isoforms, PKCdelta and PKCepsilon, in mouse and human platelets. PLoS One 2008; 3: e3793. 10.1371/journal.pone.0003793.
-
(2008)
PLoS One
, vol.3
-
-
Pears, C.J.1
Thornber, K.2
Auger, J.M.3
Hughes, C.E.4
Grygielska, B.5
Protty, M.B.6
Pearce, A.C.7
Watson, S.P.8
-
7
-
-
67349202798
-
PKCtheta is required for hemostasis and positive regulation of thrombin-induced platelet aggregation and alpha-granule secretion
-
S0006-291X(09)00914-0 [pii]. 10.1016/j.bbrc.2009.05.021.
-
Cohen S, Braiman A, Shubinsky G, Ohayon A, Altman A, Isakov N. PKCtheta is required for hemostasis and positive regulation of thrombin-induced platelet aggregation and alpha-granule secretion. Biochem Biophys Res Commun 2009; 385: 22-7. S0006-291X(09)00914-0 [pii]. 10.1016/j.bbrc.2009.05.021.
-
(2009)
Biochem Biophys Res Commun
, vol.385
, pp. 22-27
-
-
Cohen, S.1
Braiman, A.2
Shubinsky, G.3
Ohayon, A.4
Altman, A.5
Isakov, N.6
-
8
-
-
84860184374
-
Protein kinase C isoform {varepsilon} negatively regulates ADP-induced calcium mobilization and thromboxane generation in platelets
-
ATVBAHA.111.242388 [pii]. 10.1161/ATVBAHA.111.242388.
-
Bynagari-Settipalli YS, Lakhani P, Jin J, Bhavaraju K, Rico MC, Kim S, Woulfe D, Kunapuli SP. Protein kinase C isoform {varepsilon} negatively regulates ADP-induced calcium mobilization and thromboxane generation in platelets. Arterioscler Thromb Vasc Biol 2012; 32: 1211-9. ATVBAHA.111.242388 [pii]. 10.1161/ATVBAHA.111.242388.
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 1211-1219
-
-
Bynagari-Settipalli, Y.S.1
Lakhani, P.2
Jin, J.3
Bhavaraju, K.4
Rico, M.C.5
Kim, S.6
Woulfe, D.7
Kunapuli, S.P.8
-
9
-
-
77949279691
-
Diverse functions of protein kinase C isoforms in platelet activation and thrombus formation
-
JTH3722 [pii]. 10.1111/j.1538-7836.2009.03722.x.
-
Harper MT, Poole AW. Diverse functions of protein kinase C isoforms in platelet activation and thrombus formation. J Thromb Haemost 2010; 8: 454-62. JTH3722 [pii]. 10.1111/j.1538-7836.2009.03722.x.
-
(2010)
J Thromb Haemost
, vol.8
, pp. 454-462
-
-
Harper, M.T.1
Poole, A.W.2
-
10
-
-
77954945985
-
Functional divergence of platelet protein kinase C (PKC) isoforms in thrombus formation on collagen
-
M110.136176 [pii]. 10.1074/jbc.M110.136176.
-
Gilio K, Harper MT, Cosemans JM, Konopatskaya O, Munnix IC, Prinzen L, Leitges M, Liu Q, Molkentin JD, Heemskerk JW, Poole AW. Functional divergence of platelet protein kinase C (PKC) isoforms in thrombus formation on collagen. J Biol Chem 2010; 285: 23410-9. M110.136176 [pii]. 10.1074/jbc.M110.136176.
-
(2010)
J Biol Chem
, vol.285
, pp. 23410-23419
-
-
Gilio, K.1
Harper, M.T.2
Cosemans, J.M.3
Konopatskaya, O.4
Munnix, I.C.5
Prinzen, L.6
Leitges, M.7
Liu, Q.8
Molkentin, J.D.9
Heemskerk, J.W.10
Poole, A.W.11
-
11
-
-
36749062608
-
Isoform-specific functions of protein kinase C: the platelet paradigm
-
BST0351005 [pii]. 10.1042/BST0351005.
-
Harper MT, Poole AW. Isoform-specific functions of protein kinase C: the platelet paradigm. Biochem Soc Trans 2007; 35: 1005-8. BST0351005 [pii]. 10.1042/BST0351005.
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 1005-1008
-
-
Harper, M.T.1
Poole, A.W.2
-
12
-
-
61749097572
-
PKCalpha regulates platelet granule secretion and thrombus formation in mice
-
10.1172/JCI34665. 34665 [pii].
-
Konopatskaya O, Gilio K, Harper MT, Zhao Y, Cosemans JM, Karim ZA, Whiteheart SW, Molkentin JD, Verkade P, Watson SP, Heemskerk JW, Poole AW. PKCalpha regulates platelet granule secretion and thrombus formation in mice. J Clin Invest 2009; 119: 399-407. 10.1172/JCI34665. 34665 [pii].
-
(2009)
J Clin Invest
, vol.119
, pp. 399-407
-
-
Konopatskaya, O.1
Gilio, K.2
Harper, M.T.3
Zhao, Y.4
Cosemans, J.M.5
Karim, Z.A.6
Whiteheart, S.W.7
Molkentin, J.D.8
Verkade, P.9
Watson, S.P.10
Heemskerk, J.W.11
Poole, A.W.12
-
13
-
-
33747594277
-
Distinct roles for protein kinase C isoforms in regulating platelet purinergic receptor function
-
mol.106.023549 [pii]. 10.1124/mol.106.023549.
-
Mundell SJ, Jones ML, Hardy AR, Barton JF, Beaucourt SM, Conley PB, Poole AW. Distinct roles for protein kinase C isoforms in regulating platelet purinergic receptor function. Mol Pharmacol 2006; 70: 1132-42. mol.106.023549 [pii]. 10.1124/mol.106.023549.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1132-1142
-
-
Mundell, S.J.1
Jones, M.L.2
Hardy, A.R.3
Barton, J.F.4
Beaucourt, S.M.5
Conley, P.B.6
Poole, A.W.7
-
14
-
-
54749136310
-
Genetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formation
-
10.1371/journal.pone.0003277
-
Hall KJ, Harper MT, Gilio K, Cosemans JM, Heemskerk JW, Poole AW. Genetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formation. PLoS One 2008; 3: e3277. 10.1371/journal.pone.0003277.
-
(2008)
PLoS One
, vol.3
-
-
Hall, K.J.1
Harper, M.T.2
Gilio, K.3
Cosemans, J.M.4
Heemskerk, J.W.5
Poole, A.W.6
-
15
-
-
63849163448
-
Impaired activation of platelets lacking protein kinase C-theta isoform
-
blood-2008-07-169268 [pii]. 10.1182/blood-2008-07-169268.
-
Nagy B Jr, Bhavaraju K, Getz T, Bynagari YS, Kim S, Kunapuli SP. Impaired activation of platelets lacking protein kinase C-theta isoform. Blood 2009; 113: 2557-67. blood-2008-07-169268 [pii]. 10.1182/blood-2008-07-169268.
-
(2009)
Blood
, vol.113
, pp. 2557-2567
-
-
Nagy Jr., B.1
Bhavaraju, K.2
Getz, T.3
Bynagari, Y.S.4
Kim, S.5
Kunapuli, S.P.6
-
16
-
-
78649709680
-
Protein kinase C alpha enhances sodium-calcium exchange during store-operated calcium entry in mouse platelets
-
S0143-4160(10)00164-8 [pii]. 10.1016/j.ceca.2010.10.006.
-
Harper MT, Molkentin JD, Poole AW. Protein kinase C alpha enhances sodium-calcium exchange during store-operated calcium entry in mouse platelets. Cell Calcium 2010; 48: 333-40. S0143-4160(10)00164-8 [pii]. 10.1016/j.ceca.2010.10.006.
-
(2010)
Cell Calcium
, vol.48
, pp. 333-340
-
-
Harper, M.T.1
Molkentin, J.D.2
Poole, A.W.3
-
17
-
-
65549123690
-
Protein kinase C[delta] differentially regulates platelet functional responses
-
ATVBAHA.109.184010 [pii]. 10.1161/ATVBAHA.109.184010.
-
Chari R, Getz T, Nagy B Jr, Bhavaraju K, Mao Y, Bynagari YS, Murugappan S, Nakayama K, Kunapuli SP. Protein kinase C[delta] differentially regulates platelet functional responses. Arterioscler Thromb Vasc Biol 2009; 29: 699-705. ATVBAHA.109.184010 [pii]. 10.1161/ATVBAHA.109.184010.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 699-705
-
-
Chari, R.1
Getz, T.2
Nagy Jr., B.3
Bhavaraju, K.4
Mao, Y.5
Bynagari, Y.S.6
Murugappan, S.7
Nakayama, K.8
Kunapuli, S.P.9
-
18
-
-
33645990604
-
A role for PKCtheta in outside-in alpha(IIb)beta3 signaling
-
JTH1806 [pii]. 10.1111/j.1538-7836.2006.01806.x.
-
Soriani A, Moran B, de Virgilio M, Kawakami T, Altman A, Lowell C, Eto K, Shattil SJ. A role for PKCtheta in outside-in alpha(IIb)beta3 signaling. J Thromb Haemost 2006; 4: 648-55. JTH1806 [pii]. 10.1111/j.1538-7836.2006.01806.x.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 648-655
-
-
Soriani, A.1
Moran, B.2
de Virgilio, M.3
Kawakami, T.4
Altman, A.5
Lowell, C.6
Eto, K.7
Shattil, S.J.8
-
19
-
-
0038712739
-
Direct demonstration of involvement of protein kinase Calpha in the Ca2+-induced platelet aggregation
-
10.1074/jbc.M212407200. M212407200 [pii].
-
Tabuchi A, Yoshioka A, Higashi T, Shirakawa R, Nishioka H, Kita T, Horiuchi H. Direct demonstration of involvement of protein kinase Calpha in the Ca2+-induced platelet aggregation. J Biol Chem 2003; 278: 26374-9. 10.1074/jbc.M212407200. M212407200 [pii].
-
(2003)
J Biol Chem
, vol.278
, pp. 26374-26379
-
-
Tabuchi, A.1
Yoshioka, A.2
Higashi, T.3
Shirakawa, R.4
Nishioka, H.5
Kita, T.6
Horiuchi, H.7
-
20
-
-
79958734808
-
Submaximal inhibition of protein kinase C restores ADP-induced dense granule secretion in platelets in the presence of Ca2+
-
M110.187138 [pii]. 10.1074/jbc.M110.187138.
-
Unsworth AJ, Smith H, Gissen P, Watson SP, Pears CJ. Submaximal inhibition of protein kinase C restores ADP-induced dense granule secretion in platelets in the presence of Ca2+. J Biol Chem 2011; 286: 21073-82. M110.187138 [pii]. 10.1074/jbc.M110.187138.
-
(2011)
J Biol Chem
, vol.286
, pp. 21073-21082
-
-
Unsworth, A.J.1
Smith, H.2
Gissen, P.3
Watson, S.P.4
Pears, C.J.5
-
21
-
-
67651120042
-
PKCtheta in platelet activation
-
author reply 91-2. 114/2/489 [pii]. 10.1182/blood-2009-03-208454.
-
Harper MT, Poole AW. PKCtheta in platelet activation. Blood 2009; 114: 489-91; author reply 91-2. 114/2/489 [pii]. 10.1182/blood-2009-03-208454.
-
(2009)
Blood
, vol.114
, pp. 489-491
-
-
Harper, M.T.1
Poole, A.W.2
-
22
-
-
70449572926
-
Role of PKC theta in collagen-related peptide-induced platelet activation Response
-
DOI 10.1182/blood-2009-05-219022.
-
Kunapuli SP, Jin JG. Role of PKC theta in collagen-related peptide-induced platelet activation Response. Blood 2009; 114: 491-2. DOI 10.1182/blood-2009-05-219022.
-
(2009)
Blood
, vol.114
, pp. 491-492
-
-
Kunapuli, S.P.1
Jin, J.G.2
-
23
-
-
68049086486
-
Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach
-
CIRCRESAHA.109.195313 [pii]. 10.1161/CIRCRESAHA.109.195313.
-
Liu Q, Chen X, Macdonnell SM, Kranias EG, Lorenz JN, Leitges M, Houser SR, Molkentin JD. Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach. Circ Res 2009; 105: 194-200. CIRCRESAHA.109.195313 [pii]. 10.1161/CIRCRESAHA.109.195313.
-
(2009)
Circ Res
, vol.105
, pp. 194-200
-
-
Liu, Q.1
Chen, X.2
Macdonnell, S.M.3
Kranias, E.G.4
Lorenz, J.N.5
Leitges, M.6
Houser, S.R.7
Molkentin, J.D.8
-
24
-
-
0033532146
-
Reconstitution of Btk signaling by the atypical tec family tyrosine kinases Bmx and Txk
-
Tomlinson MG, Kurosaki T, Berson AE, Fujii GH, Johnston JA, Bolen JB. Reconstitution of Btk signaling by the atypical tec family tyrosine kinases Bmx and Txk. J Biol Chem 1999; 274: 13577-85.
-
(1999)
J Biol Chem
, vol.274
, pp. 13577-13585
-
-
Tomlinson, M.G.1
Kurosaki, T.2
Berson, A.E.3
Fujii, G.H.4
Johnston, J.A.5
Bolen, J.B.6
-
25
-
-
1542284064
-
Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for Tec
-
Tomlinson MG, Kane LP, Su J, Kadlecek TA, Mollenauer MN, Weiss A. Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for Tec. Mol Cell Biol 2004; 24: 2455-66.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 2455-2466
-
-
Tomlinson, M.G.1
Kane, L.P.2
Su, J.3
Kadlecek, T.A.4
Mollenauer, M.N.5
Weiss, A.6
-
26
-
-
58249088259
-
Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains
-
BJ20081126 [pii]. 10.1042/BJ20081126.
-
Protty MB, Watkins NA, Colombo D, Thomas SG, Heath VL, Herbert JM, Bicknell R, Senis YA, Ashman LK, Berditchevski F, Ouwehand WH, Watson SP, Tomlinson MG. Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains. Biochem J 2009; 417: 391-400. BJ20081126 [pii]. 10.1042/BJ20081126.
-
(2009)
Biochem J
, vol.417
, pp. 391-400
-
-
Protty, M.B.1
Watkins, N.A.2
Colombo, D.3
Thomas, S.G.4
Heath, V.L.5
Herbert, J.M.6
Bicknell, R.7
Senis, Y.A.8
Ashman, L.K.9
Berditchevski, F.10
Ouwehand, W.H.11
Watson, S.P.12
Tomlinson, M.G.13
-
27
-
-
33750571429
-
Distinct but critical roles for integrin alphaIIbbeta3 in platelet lamellipodia formation on fibrinogen, collagen-related peptide and thrombin
-
EJB5500 [pii]. 10.1111/j.1742-4658.2006.05500.x.
-
Thornber K, McCarty OJ, Watson SP, Pears CJ. Distinct but critical roles for integrin alphaIIbbeta3 in platelet lamellipodia formation on fibrinogen, collagen-related peptide and thrombin. FEBS J 2006; 273: 5032-43. EJB5500 [pii]. 10.1111/j.1742-4658.2006.05500.x.
-
(2006)
FEBS J
, vol.273
, pp. 5032-5043
-
-
Thornber, K.1
McCarty, O.J.2
Watson, S.P.3
Pears, C.J.4
|