Role of PKCθ in collagen-related peptide-induced platelet activation

Blood

Volumn 114, Issue 2, 2009, Pages 491-492

  Kunapuli, Satya P ^a   Jin, Jianguo ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; PROTEIN KINASE C THETA; SNARE PROTEIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 23; SYNTAXIN 4;

BLEEDING; ENZYME ACTIVITY; ENZYME RELEASE; IN VIVO STUDY; LETTER; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; THROMBOCYTE ACTIVATION; THROMBOSIS;

EID: 70449572926     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-05-219022     Document Type: Letter

References (6)

1. Harper MT, Poole AW. PKCtheta in platelet activaiton. Blood. 2009;114:0.
2. Nagy B Jr, Bhavaraju K, Getz T, Bynagari YS, Kim S, Kunapuli SP. Impaired activation of platelets lacking protein kinase C-theta isoform. Blood. 2009;113:2557-2567.
3. Hall KJ, Harper MT, Gilio K, Cosemans JM, Heemskerk JW, Poole AW. Genetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formation. PLoS ONE. 2008;3:e3277.
4. Cohen S, Braiman A, Shubinsky G, Ohayon A, Altman A, Isakov N. PKCtheta is required for hemostasis and positive regulation of thrombin-induced platelet aggregation and alpha-granule secretion. Biochem Biophys Res Commun. 2009.
5. Chung SH, Polgar J, Reed GL. Protein kinase C phosphorylation of syntaxin 4 in thrombin-activated human platelets. J Biol Chem. 2000;275:25286-25291. (Pubitemid 30687024)
6. Flaumenhaft R, Croce K, Chen E, Furie B, Furie BC. Proteins of the exocytotic core complex mediate platelet alpha-granule secretion. Roles of vesicle-associated membrane protein, SNAP-23, and syntaxin 4. J Biol Chem. 1999;274:2492-2501. (Pubitemid 29061412)