Liquid chromatographic mass spectrometric (LC/MS/MS) determination of plasma hydroxocobalamin and cyanocobalamin concentrations after hydroxocobalamin antidote treatment for cyanide poisoning

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 905, Issue , 2012, Pages 10-16

  Schwertner, Harvey A ^a   Valtier, Sandra ^a   Bebarta, Vikhyat S ^a  

^a WILFORD HALL MEDICAL CENTER   (United States)

Author keywords

Cyanide poisoning antidote; Cyanocobalamin; Hydroxocobalamin; LC MS MS analysis; Pharmacokinetics; Porcine models

Indexed keywords

CYANIDE POISONING; CYANOCOBALAMIN; HYDROXOCOBALAMIN; LC/MS/MS; PORCINE MODELS;

CALIBRATION; COLUMN CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; PHARMACOKINETICS; PLASMAS; TISSUE;

CYANIDES;

CYANIDE; CYANOCOBALAMIN; HYDROXOCOBALAMIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALIBRATION; CHEMICAL ANALYSIS; CONTROLLED STUDY; CYANIDE POISONING; DRUG STRUCTURE; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY MASS SPECTROMETRY; MASS SPECTROMETRY; MULTIPLE REACTION MONITORING; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; VITAMIN BLOOD LEVEL;

ANIMALS; CHROMATOGRAPHY, LIQUID; HYDROXOCOBALAMIN; LIMIT OF DETECTION; LINEAR MODELS; POTASSIUM CYANIDE; REPRODUCIBILITY OF RESULTS; SWINE; TANDEM MASS SPECTROMETRY; VITAMIN B 12;

SUIDAE; SUS; SUS SCROFA;

EID: 84865718091     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.07.012     Document Type: Article

References (24)

1. Baud F.J., Barriot P., Toffis V., Riou B., Vicaut E., Lecarpentier Y., Bourdon R., Astier A., Bismuth C. N. Engl. J. Med. 1991, 325:1761.
2. Alarie Y. Crit. Rev. Toxicol. 2002, 32:259.
3. Walsh D.W., Eckstein M. Emerg. Med. Serv. 2004, 10:160.
4. Eckstein M., Maniscalco P. Prehospital Disaster Med. 2006, 121(Suppl. 2):s49.
5. Bronstein A.C., Spyker D.A., Cantilena L.R., Green J., Rumack B.H., Heard S.E. Clin. Toxicol. (Phila) 2007, 45:815.
6. Megarbane B., Delahaye A., Goldgran-Toledano D., Baud F.J. J. Chin. Med. Assoc. 2003, 66:193.
7. Garcia R., Shephard G. Pharmacotherapy 2004, 24:1358.
8. Krapez J.R., Vesey C.J., Adams L., Cole P.V. Br. J. Anaesth. 1981, 53:793.
9. Hall A.H., Dart R., Bogdan G. Ann. Emerg. Med. 2007, 49:806.
10. Sauer S.W., Keim M.E. Ann. Emerg. Med. 2001, 37:635.
11. Borron S.W., Baud F.J., Barriot P., Imbert M., Bismuth C. Ann. Emerg. Med. 2007, 49:794.
12. Borron S.W., Stonerook M., Reid F. Clin. Toxicol. 2006, 44:5.
13. Fortin J.L., Ruttiman M., Domanski L., Kowalski J.J. J. Emerg. Med. Serv. 2004, 9(Suppl.):18.
14. Forsyth J.C., Mueller P.D., Becker C.E., Osterloh J., Benowitz N.L., Rumack B.H., Hall A.H. J. Toxicol. Clin. Toxicol. 1993, 31:277.
15. Houeto P., Buneaux F., Galliot-Guilley M., Baud F.J., Levillain P. J. Anal. Toxicol. 1994, 18:154.
16. Cruz-Landeira A., Lopez-Rivadulla M., Concheiro-Carro L., Fernandez-Gomez P., Tabernero-Duque M.J. J. Anal. Toxicol. 2000, 24:266.
17. Van den Berg M.P., Merkus P., Romeijn S.G., Verhoef J.C., Merkus F.W. J. Drug Target. 2003, 11:325.
18. Vinas P., Campillo N., Lopez Garcia I., Hernandez Cordoba M. Anal. Chim. Acta 1996, 318:319.
19. Kelly R.J., Gruner T.M., Sykes A.R. Biomed. Chromatogr. 2005, 19:329.
20. Nava-Ocampo A.A., Pastrak A., Cruz T., Koren G. Clin. Exp. Pharmacol. Physiol. 2005, 32:13.
21. Suarez-Suarez A., Tovar-Sanchez A., Rosello-Mora.R. Anal. Chim. Acta 2011, 701:81.
22. Astier A., Baud F.J. J. Chromatogr. B: Biomed. Appl. 1995, 667:129.
23. Chassaigne H., Lobinski R. Analyst 1998, 123:131.
24. Bebarta V.S., Tanen D.A., Lairet J., Dixon P.S., Valtier S., Bush A. Ann. Emerg. Med. 2010, 55:345.