-
1
-
-
78049479470
-
APOE polymorphism is associated with lipid profile, but not with arterial stiffness in the general population
-
Alvim RO, Freitas SR, Ferreira NE, et al. (2010) APOE polymorphism is associated with lipid profile, but not with arterial stiffness in the general population. Lipids Health Dis 9:128.
-
(2010)
Lipids Health Dis
, vol.9
, pp. 128
-
-
Alvim, R.O.1
Freitas, S.R.2
Ferreira, N.E.3
-
2
-
-
79961134642
-
Influence of genetic, biological and pharmacological factors on warfarin dose in a Southern Brazilian population of European ancestry
-
Botton MR, Bandinelli E, Rohde LE, et al. (2011) Influence of genetic, biological and pharmacological factors on warfarin dose in a Southern Brazilian population of European ancestry. Br J Clin Pharmacol 72:442-450.
-
(2011)
Br J Clin Pharmacol
, vol.72
, pp. 442-450
-
-
Botton, M.R.1
Bandinelli, E.2
Rohde, L.E.3
-
3
-
-
42149188553
-
CYP4F2 genetic variant alters required warfarin dose
-
Caldwell MD, Awad T, Johnson JA, et al. (2008) CYP4F2 genetic variant alters required warfarin dose. Blood 111:4106-4112.
-
(2008)
Blood
, vol.111
, pp. 4106-4112
-
-
Caldwell, M.D.1
Awad, T.2
Johnson, J.A.3
-
4
-
-
77949873283
-
Genetic and clinical predictors of warfarin dose requirements in African Americans
-
Cavallari LH, Langaee TY, Momary KM, et al. (2010) Genetic and clinical predictors of warfarin dose requirements in African Americans. Clin Pharmacol Ther 87:459-464.
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 459-464
-
-
Cavallari, L.H.1
Langaee, T.Y.2
Momary, K.M.3
-
5
-
-
77953304931
-
Warfarin genotyping reduces hospitalization rates results from the MM-WES (Medco-Mayo Warfarin Effectiveness study)
-
Epstein RS, Moyer TP, Aubert RE, et al. (2011) Warfarin genotyping reduces hospitalization rates results from the MM-WES (Medco-Mayo Warfarin Effectiveness study). J Am Coll Cardiol 55:2804-2812.
-
(2011)
J Am Coll Cardiol
, vol.55
, pp. 2804-2812
-
-
Epstein, R.S.1
Moyer, T.P.2
Aubert, R.E.3
-
6
-
-
73049117322
-
Ability of VKORC1 and CYP2C9 to predict therapeutic warfarin dose during the initial weeks of therapy
-
Ferder NS, Eby CS, Deych E, et al. (2010) Ability of VKORC1 and CYP2C9 to predict therapeutic warfarin dose during the initial weeks of therapy. J Thromb Haemost 8:95-100.
-
(2010)
J Thromb Haemost
, vol.8
, pp. 95-100
-
-
Ferder, N.S.1
Eby, C.S.2
Deych, E.3
-
8
-
-
47949086046
-
Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin
-
Gage BF, Eby C, Johnson JA, et al. (2008) Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin. Clin Pharmacol Ther 84:326-331.
-
(2008)
Clin Pharmacol Ther
, vol.84
, pp. 326-331
-
-
Gage, B.F.1
Eby, C.2
Johnson, J.A.3
-
9
-
-
27144539568
-
VKORC1 haplotypes and their impact on the inter-individual and interethnical variability of oral anticoagulation
-
Geisen C, Watzka M, Sittinger K, et al. (2005) VKORC1 haplotypes and their impact on the inter-individual and interethnical variability of oral anticoagulation. Thromb Haemost 94:773-779.
-
(2005)
Thromb Haemost
, vol.94
, pp. 773-779
-
-
Geisen, C.1
Watzka, M.2
Sittinger, K.3
-
10
-
-
77953308585
-
The long and winding road to warfarin pharmacogenetic testing
-
Ginsburg GS, Voora D (2010) The long and winding road to warfarin pharmacogenetic testing. J Am Coll Cardiol 55:2813-2815.
-
(2010)
J Am Coll Cardiol
, vol.55
, pp. 2813-2815
-
-
Ginsburg, G.S.1
Voora, D.2
-
11
-
-
83255185151
-
Brazilian urban population genetic structure reveals a high degree of admixture
-
Giolo SR, Soler JM, Greenway SC, et al. (2011) Brazilian urban population genetic structure reveals a high degree of admixture. Eur J Hum Genet 20:111-116.
-
(2011)
Eur J Hum Genet
, vol.20
, pp. 111-116
-
-
Giolo, S.R.1
Soler, J.M.2
Greenway, S.C.3
-
12
-
-
0037012465
-
Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy
-
Higashi MK, Veenstra DL, Kondo LM, et al. (2002) Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy. JAMA 287:1690-1698.
-
(2002)
JAMA
, vol.287
, pp. 1690-1698
-
-
Higashi, M.K.1
Veenstra, D.L.2
Kondo, L.M.3
-
13
-
-
0035128503
-
Oral anticoagulants: Mechanism of action, clinical effectiveness, and optimal therapeutic range
-
Hirsh J, Dalen J, Anderson DR, et al. (2001) Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest 119:8S-21S.
-
(2001)
Chest
, vol.119
-
-
Hirsh, J.1
Dalen, J.2
Anderson, D.R.3
-
14
-
-
2942620708
-
Cytochrome P450 2C9 phenotyping using low-dose tolbutamide
-
Jetter A, Kinzig-Schippers M, Skott A, et al. (2004) Cytochrome P450 2C9 phenotyping using low-dose tolbutamide. Eur J Clin Pharmacol 60:165-171.
-
(2004)
Eur J Clin Pharmacol
, vol.60
, pp. 165-171
-
-
Jetter, A.1
Kinzig-Schippers, M.2
Skott, A.3
-
15
-
-
80052969185
-
Pharmacogenomics: Application to the management of cardiovascular disease
-
Johnson JA, Cavallari LH, Beitelshees AL, et al. (2011) Pharmacogenomics: application to the management of cardiovascular disease. Clin Pharmacol Ther 90:519-531.
-
(2011)
Clin Pharmacol Ther
, vol.90
, pp. 519-531
-
-
Johnson, J.A.1
Cavallari, L.H.2
Beitelshees, A.L.3
-
16
-
-
10744229776
-
Effects of CYP2C9 polymorphisms on the pharmacokinetics of R-and Sphenprocoumon in healthy volunteers
-
Kirchheiner J, Ufer M, Walter EC, et al. (2004) Effects of CYP2C9 polymorphisms on the pharmacokinetics of R-and Sphenprocoumon in healthy volunteers. Pharmacogenetics 14:19-26.
-
(2004)
Pharmacogenetics
, vol.14
, pp. 19-26
-
-
Kirchheiner, J.1
Ufer, M.2
Walter, E.C.3
-
17
-
-
79954514722
-
Pharmacogenomic testing: Relevance in medical practice: Why drugs work in some patients but not in others
-
Kitzmiller JP, Groen DK, Phelps MA, et al. (2011) Pharmacogenomic testing: relevance in medical practice: why drugs work in some patients but not in others. Cleve Clin J Med 78:243-257.
-
(2011)
Cleve Clin J Med
, vol.78
, pp. 243-257
-
-
Kitzmiller, J.P.1
Groen, D.K.2
Phelps, M.A.3
-
18
-
-
60849097257
-
Estimation of the warfarin dose with clinical and pharmacogenetic data
-
Klein TE, Altman RB, Eriksson N, et al. (2009) Estimation of the warfarin dose with clinical and pharmacogenetic data. N Engl J Med 360:753-764.
-
(2009)
N Engl J Med
, vol.360
, pp. 753-764
-
-
Klein, T.E.1
Altman, R.B.2
Eriksson, N.3
-
19
-
-
0027257511
-
Anticoagulant-related bleeding: Clinical epidemiology, prediction, and prevention
-
Landefeld CS, Beyth RJ (1993) Anticoagulant-related bleeding: clinical epidemiology, prediction, and prevention. Am J Med 95:315-328.
-
(1993)
Am J Med
, vol.95
, pp. 315-328
-
-
Landefeld, C.S.1
Beyth, R.J.2
-
20
-
-
77951498679
-
Integration of genetic, clinical, and INR data to refine warfarin dosing
-
Lenzini P, Wadelius M, Kimmel S, et al. (2010) Integration of genetic, clinical, and INR data to refine warfarin dosing. Clin Pharmacol Ther 87:572-578.
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 572-578
-
-
Lenzini, P.1
Wadelius, M.2
Kimmel, S.3
-
21
-
-
33749258021
-
Polymorphisms in the VKORC1 gene are strongly associated with warfarin dosage requirements in patients receiving anticoagulation
-
Li T, Lange LA, Li X, et al. (2006) Polymorphisms in the VKORC1 gene are strongly associated with warfarin dosage requirements in patients receiving anticoagulation. J Med Genet 43:740-744.
-
(2006)
J Med Genet
, vol.43
, pp. 740-744
-
-
Li, T.1
Lange, L.A.2
Li, X.3
-
22
-
-
38349126516
-
Influence of CYP2C9 and VKORC1 1173C/T genotype on the risk of hemorrhagic complications in African-American and European-American patients on warfarin
-
Limdi NA, McGwin G, Goldstein JA, et al. (2008) Influence of CYP2C9 and VKORC1 1173C/T genotype on the risk of hemorrhagic complications in African-American and European-American patients on warfarin. Clin Pharmacol Ther 83:312-321.
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 312-321
-
-
Limdi, N.A.1
McGwin, G.2
Goldstein, J.A.3
-
23
-
-
77952570889
-
Warfarin pharmacogenetics: A single VKORC1 polymorphism is predictive of dose across 3 racial groups
-
Limdi NA, Wadelius M, Cavallari L, et al. (2010) Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups. Blood 115:3827-3834.
-
(2010)
Blood
, vol.115
, pp. 3827-3834
-
-
Limdi, N.A.1
Wadelius, M.2
Cavallari, L.3
-
24
-
-
33947231296
-
A coding VKORC1 Asp36Tyr polymorphism predisposes to warfarin resistance
-
Loebstein R, Dvoskin I, Halkin H, et al. (2007) A coding VKORC1 Asp36Tyr polymorphism predisposes to warfarin resistance. Blood 109:2477-2480.
-
(2007)
Blood
, vol.109
, pp. 2477-2480
-
-
Loebstein, R.1
Dvoskin, I.2
Halkin, H.3
-
25
-
-
58849108280
-
Prevalence and risk factors associated with peripheral arterial disease in the Hearts of Brazil Project
-
Makdisse M, Pereira AC, Brasil Dde P, et al. (2008) Prevalence and risk factors associated with peripheral arterial disease in the Hearts of Brazil Project. Arq Bras Cardiol 91:370-382.
-
(2008)
Arq Bras Cardiol
, vol.91
, pp. 370-382
-
-
Makdisse, M.1
Pereira, A.C.2
Brasil Dde, P.3
-
26
-
-
73249134561
-
Agedependent increase in blood pressure in two different Native American communities in Brazil
-
Meyerfreund D, Goncalves C, Cunha R, et al. (2009) Agedependent increase in blood pressure in two different Native American communities in Brazil. J Hypertens 27:1753-1760.
-
(2009)
J Hypertens
, vol.27
, pp. 1753-1760
-
-
Meyerfreund, D.1
Goncalves, C.2
Cunha, R.3
-
27
-
-
84864364455
-
Optimization of warfarin dose by population-specific pharmacogenomic algorithm
-
Epub ahead of print; Doi:10.1038/tpj.2011.4
-
Pavani A, Naushad SM, Rupasree Y, et al. (2011) Optimization of warfarin dose by population-specific pharmacogenomic algorithm. Pharmacogenomics J [Epub ahead of print]; Doi:10.1038/tpj.2011.4.
-
(2011)
Pharmacogenomics J
-
-
Pavani, A.1
Naushad, S.M.2
Rupasree, Y.3
-
28
-
-
79951895658
-
The genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expected
-
Pena SD, Di Pietro G, Fuchshuber-Moraes M, et al. (2011) The genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expected. PLoS One 6:e17063.
-
(2011)
PLoS One
, vol.6
-
-
Pena, S.D.1
Di Pietro, G.2
Fuchshuber-Moraes, M.3
-
29
-
-
79951811694
-
The missing association: Sequencing-based discovery of novel SNPs in VKORC1 and CYP2C9 that affect warfarin dose in African Americans
-
Perera MA, Gamazon E, Cavallari LH, et al. (2011) The missing association: sequencing-based discovery of novel SNPs in VKORC1 and CYP2C9 that affect warfarin dose in African Americans. Clin Pharmacol Ther 89:408-415.
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 408-415
-
-
Perera, M.A.1
Gamazon, E.2
Cavallari, L.H.3
-
30
-
-
33845752027
-
Color and genomic ancestry in Brazilians: A study with forensic microsatellites
-
Pimenta JR, Zuccherato LW, Debes AA, et al. (2006) Color and genomic ancestry in Brazilians: a study with forensic microsatellites. Hum Hered 62:190-195.
-
(2006)
Hum Hered
, vol.62
, pp. 190-195
-
-
Pimenta, J.R.1
Zuccherato, L.W.2
Debes, A.A.3
-
31
-
-
21144448879
-
Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose
-
Rieder MJ, Reiner AP, Gage BF, et al. (2005) Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose. N Engl J Med 352:2285-2293.
-
(2005)
N Engl J Med
, vol.352
, pp. 2285-2293
-
-
Rieder, M.J.1
Reiner, A.P.2
Gage, B.F.3
-
33
-
-
84857035975
-
SLCO1B1 haplotypes are not associated with atorvastatin-induced myalgia in Brazilian patients with familial hypercholesterolemia
-
Santos PC, Gagliardi AC, Miname MH, et al. (2012) SLCO1B1 haplotypes are not associated with atorvastatin-induced myalgia in Brazilian patients with familial hypercholesterolemia. Eur J Clin Pharmacol 68:273-279.
-
(2012)
Eur J Clin Pharmacol
, vol.68
, pp. 273-279
-
-
Santos, P.C.1
Gagliardi, A.C.2
Miname, M.H.3
-
34
-
-
80054903877
-
Genotyping of the hemochromatosis HFE p. H63D and p. C282Y mutations by high-resolution melting with the Rotor-Gene 6000 ((R)) instrument
-
Santos PC, Soares RA, Krieger JE, et al. (2011b) Genotyping of the hemochromatosis HFE p. H63D and p. C282Y mutations by high-resolution melting with the Rotor-Gene 6000 ((R)) instrument. Clin Chem Lab Med 49:1633-1636.
-
(2011)
Clin Chem Lab Med
, vol.49
, pp. 1633-1636
-
-
Santos, P.C.1
Soares, R.A.2
Krieger, J.E.3
-
35
-
-
80053928744
-
SLCO1B1 rs4149056 polymorphism associated with statin-induced myopathy is differently distributed according to ethnicity in the Brazilian general population: Amerindians as a high risk ethnic group
-
Santos PC, Soares RA, Nascimento RM, et al. (2011c) SLCO1B1 rs4149056 polymorphism associated with statin-induced myopathy is differently distributed according to ethnicity in the Brazilian general population: Amerindians as a high risk ethnic group. BMC Med Genet 12:136.
-
(2011)
BMC Med Genet
, vol.12
, pp. 136
-
-
Santos, P.C.1
Soares, R.A.2
Nascimento, R.M.3
-
36
-
-
78651498123
-
CYP2C19 and ABCB1 gene polymorphisms are differently distributed according to ethnicity in the Brazilian general population
-
Santos PC, Soares RA, Santos DB, et al. (2011d) CYP2C19 and ABCB1 gene polymorphisms are differently distributed according to ethnicity in the Brazilian general population. BMC Med Genet 12:13.
-
(2011)
BMC Med Genet
, vol.12
, pp. 13
-
-
Santos, P.C.1
Soares, R.A.2
Santos, D.B.3
-
37
-
-
40449120615
-
Genetic determinants of response to warfarin during initial anticoagulation
-
Schwarz UI, Ritchie MD, Bradford Y, et al. (2008) Genetic determinants of response to warfarin during initial anticoagulation. N Engl J Med 358:999-1008.
-
(2008)
N Engl J Med
, vol.358
, pp. 999-1008
-
-
Schwarz, U.I.1
Ritchie, M.D.2
Bradford, Y.3
-
38
-
-
23044440450
-
The impact of CYP2C9 and VKORC1 genetic polymorphism and patient new dosing regimen
-
Sconce EA, Khan TI, Wynne HA, et al. (2005) The impact of CYP2C9 and VKORC1 genetic polymorphism and patient new dosing regimen. Blood 106:2329-2333.
-
(2005)
Blood
, vol.106
, pp. 2329-2333
-
-
Sconce, E.A.1
Khan, T.I.2
Wynne, H.A.3
-
39
-
-
77952927473
-
Combined CYP2C9, VKORC1 and CYP4F2 frequencies among racial and ethnic groups
-
Scott SA, Khasawneh R, Peter I, et al. (2011) Combined CYP2C9, VKORC1 and CYP4F2 frequencies among racial and ethnic groups. Pharmacogenomics 11:781-791.
-
(2011)
Pharmacogenomics
, vol.11
, pp. 781-791
-
-
Scott, S.A.1
Khasawneh, R.2
Peter, I.3
-
40
-
-
79961161857
-
Pharmacogenetics in the brazilian population
-
Suarez-Kurtz G (2010) Pharmacogenetics in the brazilian population. Front Pharmacol 1:118.
-
(2010)
Front Pharmacol
, vol.1
, pp. 118
-
-
Suarez-Kurtz, G.1
-
41
-
-
79961135011
-
Population diversity and the performance of warfarin dosing algorithms
-
Suarez-Kurtz G (2011) Population diversity and the performance of warfarin dosing algorithms. Br J Clin Pharmacol 72:451-453.
-
(2011)
Br J Clin Pharmacol
, vol.72
, pp. 451-453
-
-
Suarez-Kurtz, G.1
-
43
-
-
34548096907
-
Use of genetic and nongenetic factors in warfarin dosing algorithms
-
Wu AH (2007) Use of genetic and nongenetic factors in warfarin dosing algorithms. Pharmacogenomics 8:851-861.
-
(2007)
Pharmacogenomics
, vol.8
, pp. 851-861
-
-
Wu, A.H.1
-
44
-
-
79251491073
-
Pharmacoeconomic evaluation of warfarin pharmacogenomics
-
You JH (2011) Pharmacoeconomic evaluation of warfarin pharmacogenomics. Expert Opin Pharmacother 12:435-441.
-
(2011)
Expert Opin Pharmacother
, vol.12
, pp. 435-441
-
-
You, J.H.1
-
45
-
-
24944503322
-
A novel functional VKORC1 promoter polymorphism is associated with interindividual and inter-ethnic differences in warfarin sensitivity
-
Yuan HY, Chen JJ, Lee MT, et al. (2005) A novel functional VKORC1 promoter polymorphism is associated with interindividual and inter-ethnic differences in warfarin sensitivity. Hum Mol Genet 14:1745-1751.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 1745-1751
-
-
Yuan, H.Y.1
Chen, J.J.2
Lee, M.T.3
|