Influence of tumor thrombus location on the outcome of external-beam radiation therapy in advanced hepatocellular carcinoma with macrovascular invasion

International Journal of Radiation Oncology Biology Physics

Volumn 84, Issue 2, 2012, Pages 362-368

  Hou, Jia Zhou ^a   Zeng, Zhao Chong ^a   Zhang, Jian Ying ^a   Fan, Jia ^a   Zhou, Jian ^a   Zeng, Meng Su ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

External beam radiation therapy (EBRT); Hepatocellular carcinoma (HCC); Prognosis; Transcatheter arterial chemoembolization (TACE); Tumor thrombus

Indexed keywords

EXTERNAL-BEAM RADIATION THERAPY; FETOPROTEIN; HEPATOCELLULAR CARCINOMA; INFERIOR VENA CAVA; LYMPH NODE METASTASIS; MEDIAN SURVIVAL; MULTI VARIATE ANALYSIS; PORTAL VEINS; PRE-TREATMENT; PROGNOSIS; RESPONSE RATE; TRANSARTERIAL CHEMOEMBOLIZATION; TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION (TACE); UNIVARIATE;

BLOOD VESSELS; DISEASES; FAULT TOLERANT COMPUTER SYSTEMS; LIVER; MULTIVARIANT ANALYSIS; NATURAL LANGUAGE PROCESSING SYSTEMS; RADIOTHERAPY; TUMORS;

DIAGNOSIS;

ALBUMIN; ALPHA FETOPROTEIN;

ADULT; ADVANCED CANCER; ARTICLE; CANCER INVASION; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CHEMOEMBOLIZATION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; ECHOGRAPHY; EXTERNAL BEAM RADIOTHERAPY; FEMALE; HUMAN; INFERIOR CAVA VEIN; LIVER CELL CARCINOMA; MACROVASCULAR INVASION; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PORTAL VEIN; PRIORITY JOURNAL; RADIATION DOSE; RETROSPECTIVE STUDY; SURVIVAL TIME; THROMBUS; TREATMENT OUTCOME; TREATMENT RESPONSE; TUMOR THROMBUS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; CARCINOMA, HEPATOCELLULAR; CHEMOEMBOLIZATION, THERAPEUTIC; CHILD; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; PORTAL VEIN; PROGNOSIS; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, CONFORMAL; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; TUMOR BURDEN; VENA CAVA, INFERIOR; VENOUS THROMBOSIS; YOUNG ADULT;

EID: 84865661729     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2011.12.024     Document Type: Article

References (24)

1. M. Pirisi, C. Avellini, and C. Fabris Portal vein thrombosis in hepatocellular carcinoma: Age and sex distribution in an autopsy study J Cancer Res Clin Oncol 124 1998 397 400
2. K.W. Park, J.W. Park, and J.I. Choi Survival analysis of 904 patients with hepatocellular carcinoma in a hepatitis B virus-endemic area J Gastroenterol Hepatol 2007 10.1111/j.1440-1746.2007.05112.x
3. Y. Fong, R.L. Sun, W. Jarnagin, and L.H. Blumgart An analysis of 412 cases of hepatocellular carcinoma at a Western Center Ann Surg 229 1999 790 800
4. T.K. Cheung, C.L. Lai, and C.Y. Wong Clinical features, biochemical parameters, and virological profiles of patients with hepatocellular carcinoma in Hong Kong Aliment Pharmacol Ther 24 2006 573 583
5. D. Takizawa, S. Kakizaki, and N. Sohara Hepatocellular carcinoma with portal vein tumor thrombosis: Clinical characteristics, prognosis, and patient survival analysis Dig Dis Sci 52 2007 3290 3295
6. J.M. Liovet, J. Bustamante, and A. Castells Natural history of untreated nonsurgical hepatocellular carcinoma: Rationale for the design and evaluation of therapeutic trials Hepatology 29 1999 62 67
7. J.Y. Cheong, K.M. Lee, and S.W. Cho Survival benefits to intra-arterial infusion chemotherapy in patients with advanced hepatocellular carcinoma with portal vein tumor thrombosis Hepatol Res 32 2005 127 133
8. J.W. Jang, S.H. Bae, and J.Y. Choi A combination therapy with transarterial chemo-lipoidolization and systemic chemo-infusion for large extensive hepatocellular carcinoma invading portal vein in comparison with conservative management Cancer Chemother Pharmacol 59 2007 9 15
9. S. Okada How to manage hepatic vein tumour thrombus in hepatocellular carcinoma J Gastroenterol Hepatol 15 2000 346 348
10. Y.P. Le Treut, J. Hardwigsen, and P. Ananian Resection of hepatocellular carcinoma with tumor thrombus in the major vasculature. A European case-control series J Gastrointest Surg 10 2006 855 862
11. I.J. Lee, J.W. Chung, and H.C. Kim Extrahepatic collateral artery supply to the tumor thrombi of hepatocellular carcinoma invading inferior vena cava: The prevalence and determinant factors J Vasc Interv Radiol 2009 22 29 8
12. E. Ando, M. Tanaka, and F. Yamashita Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombosis: Analysis of 48 cases Cancer 95 2002 588 595
13. M.A. Hawkins, and L.A. Dawson Radiation therapy for hepatocellular carcinoma: From palliation to cure Cancer 106 2006 1653 1663
14. S. Krishnan, L.A. Dawson, and J. Seong Radiotherapy for hepatocellular carcinoma: An overview Ann Surg Oncol 15 2008 1015 1024
15. M. Fuss, B.J. Salter, and T.S. Herman External beam radiation therapy for hepatocellular carcinoma: Potential of intensity modulated and image-guided radiation therapy Gastroenterology 127 2004 S206 S217
16. Z.C. Zeng, J. Fan, and Z.Y. Tang A comparison of treatment combinations with and without radiotherapy for hepatocellular carcinoma with portal vein and/or inferior vena cava tumor thrombus Int J Radiat Oncol Biol Phys 61 2005 432 443
17. H. Igaki, K. Nakagawa, and K. Shiraishi Three-dimensional conformal radiotherapy for hepatocellular carcinoma with inferior vena cava invasion Jpn J Clin Oncol 38 2008 438 444
18. M. Mizumoto, K. Tokuuye, and S. Sugahara Proton beam therapy for hepatocellular carcinoma with inferior vena cava tumor thrombus: Report of three cases Jpn J Clin Oncol 37 2007 459 462
19. J. Bruix, and M. Sherman Management of gepatocellular carcinoma Hepatology 42 2005 1208 1236
20. J. Tazawa, M. Maeda, and Y. Sakai Radiation therapy in combination with transcatheter arterial chemoembolization for hepatocellular carcinoma with extensive portal vein involvement J Gastroenterol Hepatol 16 2001 660 665
21. S. Ishikura, T. Ogino, and J. Furuse Radiotherapy after transcatheter arterial chemoembolization for patients with hepatocellular carcinoma and portal vein tumor thrombus Am J Clin Oncol 25 2002 189 193
22. K. Yamada, K. Izaki, and K. Sugimoto Prospective trial of combined transcatheter arterial chemoembolization and three-dimensional conformal radiotherapy for portal vein tumor thrombus in patients with unresectable hepatocellular carcinoma Int J Radiat Oncol Biol Phys 57 2003 113 119
23. J.E. Koo, J.H. Kim, and Y.S. Lim Combination of transarterial chemoemobolization and three-dimensional conformal radiotherapy for hepatocellular carcinoma with inferior vena cava tumor thrombus Int J Radiat Oncol Biol Phys 78 2010 180 187
24. C. Dominique, and C. Bertrand Portal vein thrombosis in adults: Pathophysiology, pathogenesis and management J Hepatol 32 2000 865 871