Short-term exercise training augments sympathetic vasoconstrictor responsiveness and endothelium-dependent vasodilation in resting skeletal muscle

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 303, Issue 3, 2012, Pages 332-339

  Jendzjowsky, Nicholas G ^a   DeLorey, Darren S ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Blood flow; Exercise intensity; Nitric oxide; Sympathetic nervous system

Indexed keywords

ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; CONDUCTANCE; CONTROLLED STUDY; ENDOTHELIUM DEPENDENT VASODILATION; EXERCISE; FEMORAL ARTERY FLOW; FEMORAL VASCULAR CONDUCTANCE; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RANDOMIZATION; RAT; REST; SEDENTARY LIFESTYLE; SHORT TERM EXERCISE TRAINING; SKELETAL MUSCLE; SYMPATHETIC NERVE; SYMPATHETIC VASOCONSTRICTION; VASOCONSTRICTION; VASODILATATION;

ACETYLCHOLINE; ANIMALS; BLOOD PRESSURE; ELECTRIC STIMULATION; ENDOTHELIUM, VASCULAR; MALE; MODELS, ANIMAL; MUSCLE, SKELETAL; PHYSICAL CONDITIONING, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW; REST; SYMPATHETIC NERVOUS SYSTEM; TIME FACTORS; VASOCONSTRICTION; VASODILATION; VASODILATOR AGENTS;

EID: 84865660781     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00053.2012     Document Type: Article

References (56)

1. Armstrong RB, Laughlin MH. Exercise blood flow patterns within and among rat muscles after training. Am J Physiol Heart Circ Physiol 246: H59-H68, 1984.
2. Armstrong RB, Laughlin MH. Metabolic indicators of fibre recruitment in mammalian muscles during locomotion. J Exp Biol 115: 201-213, 1985.
3. Behnke BJ, Armstrong RB, Delp MD. Adrenergic control of vascular resistance varies in muscles composed of different fiber types: influence of the vascular endothelium. Am J Physiol Regul Integr Comp Physiol 301: R783-R790, 2011.
4. Bradley E, Law A, Bell D, Johnson CD. Effects of varying impulse number on cotransmitter contributions to sympathetic vasoconstriction in rat tail artery. Am J Physiol Heart Circ Physiol 284: H2007-H2014, 2003.
5. 1 receptor vasoconstriction in exercising canine skeletal muscles. J Appl Physiol 99: 2115-2120, 2005.
6. Buckwalter JB, Hamann JJ, Clifford PS. Vasoconstriction in active skeletal muscles: a potential role for P2X purinergic receptors? J Appl Physiol 95: 953-959, 2003.
7. Buckwalter JB, Hamann JJ, Kluess HA, Clifford PS. Vasoconstriction in exercising skeletal muscles: a potential role for neuropeptide Y? Am J Physiol Heart Circ Physiol 287: H144-H149, 2004.
8. Buckwalter JB, Taylor JC, Hamann JJ, Clifford PS. Do P2X purinergic receptors regulate skeletal muscle blood flow during exercise? Am J Physiol Heart Circ Physiol 286: H633-H639, 2004.
9. Burnstock G. Cotransmission. Curr Opin Pharmacol 4: 47-52, 2004.
10. Burnstock G. Integration of factors controlling vascular tone. Overview. Anesthesiology 79: 1368-1380, 1993.
11. Coney AM, Marshall JM. Contribution of adenosine to the depression of sympathetically evoked vasoconstriction induced by systemic hypoxia in the rat. J Physiol 549: 613-623, 2003.
12. 1 neuropeptide Y receptors to the blunting of sympathetic vasocon-striction induced by systemic hypoxia in the rat. J Physiol 582: 1349-1359, 2007.
13. DeLorey DS, Buckwalter JB, Mittelstadt SW, Anton MM, Kluess HA, Clifford PS. Is tonic sympathetic vasoconstriction increased in the skeletal muscle vasculature of aged canines? Am J Physiol Regul Integr Comp Physiol 299: R1342-R1349, 2010.
14. Delorey DS, Clifford PS, Mittelstadt S, Anton MM, Kluess HA, Tune JD, Dincer UD, Buckwalter JB. The effect of aging on adrenergic and nonadrenergic receptor expression and responsiveness in canine skeletal muscle. J Appl Physiol 112: 841-848, 2012.
15. Delp MD. Differential effects of training on the control of skeletal muscle perfusion. Med Sci Sports Exerc 30: 361-374, 1998.
16. Delp MD. Effects of exercise training on endothelium-dependent peripheral vascular responsiveness. Med Sci Sports Exerc 27: 1152-1157, 1995.
17. Delp MD, McAllister RM, Laughlin MH. Exercise training alters endothelium-dependent vasoreactivity of rat abdominal aorta. J Appl Physiol 75: 1354-1363, 1993.
18. Dibona GF, Sawin LL. Functional significance of the pattern of renal sympathetic nerve activation. Am J Physiol Regul Integr Comp Physiol 277: R346-R353, 1999.
19. Donato AJ, Lesniewski LA, Delp MD. Ageing and exercise training alter adrenergic vasomotor responses of rat skeletal muscle arterioles. J Physiol 579: 115-125, 2007.
20. Grassi G, Seravalle G, Calhoun DA, Mancia G. Physical training and baroreceptor control of sympathetic nerve activity in humans. Hypertension 23: 294-301, 1994.
21. Green DJ, Maiorana A, O'Driscoll G, Taylor R. Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol 561: 1-25, 2004.
22. Haniuda K, Nakane T, Chiba S. Different contributions of ATP and noradrenaline to neurotransmission in the isolated canine intermediate auricular artery. Eur J Pharmacol 333: 163-168, 1997.
23. Hudson S, Johnson CD, Coney AM, Marshall JM. Changes in sympathetic nerve activity recorded from skeletal muscle arteries of the anaesthetized rat during graded levels of systemic hypoxia. J Physiol 544: 28P, 2002.
24. Jasperse JL, Laughlin MH. Vasomotor responses of soleus feed arteries from sedentary and exercise-trained rats. J Appl Physiol 86: 441-449, 1999.
25. Jendzjowsky NG, DeLorey DS. A prospective evaluation of non-interval- and interval-based exercise training progressions in rodents. Appl Physiol Nutr Metab 36: 723-729, 2011.
26. Johnson CD, Coney AM, Marshall JM. Roles of norepinephrine and ATP in sympathetically evoked vasoconstriction in rat tail and hindlimb in vivo. Am J Physiol Heart Circ Physiol 281: H2432-H2440, 2001.
27. Koller A, Huang A, Sun D, Kaley G. Exercise training augments flow-dependent dilation in rat skeletal muscle arterioles. Role of endothelial nitric oxide and prostaglandins. Circ Res 76: 544-550, 1995.
28. Lash JM. Exercise training enhances adrenergic constriction and dilation in the rat spinotrapezius muscle. J Appl Physiol 85: 168-174, 1998.
29. Laughlin MH, Armstrong RB. Muscle blood flow during locomotory exercise. Exerc Sport Sci Rev 13: 95-136, 1985.
30. Laughlin MH, Armstrong RB. Muscular blood flow distribution patterns as a function of running speed in rats. Am J Physiol Heart Circ Physiol 243: H296-H306, 1982.
31. Laughlin MH, Mohrman SJ, Armstrong RB. Muscular blood flow distribution patterns in the hindlimb of swimming rats. Am J Physiol Heart Circ Physiol 246: H398-H403, 1984.
32. Laughlin MH, Ripperger J. Vascular transport capacity of hindlimb muscles of exercise-trained rats. J Appl Physiol 62: 438-443, 1987.
33. Laughlin MH, Roseguini B. Mechanisms for exercise training-induced increases in skeletal muscle blood flow capacity: differences with interval sprint training versus aerobic endurance training. J Physiol Pharmacol 59 Suppl 7: 71-88, 2008.
34. Laughlin MH, Woodman CR, Schrage WG, Gute D, Price EM. Interval sprint training enhances endothelial function and eNOS content in some arteries that perfuse white gastrocnemius muscle. J Appl Physiol 96: 233-244, 2004.
35. Li Y, Zheng J, Bird IM, Magness RR. Effects of pulsatile shear stress on signaling mechanisms controlling nitric oxide production, endothelial nitric oxide synthase phosphorylation, and expression in ovine fetoplacen-tal artery endothelial cells. Endothelium 12: 21-39, 2005.
36. Linderman JR, Boegehold MA. Modulation of arteriolar sympathetic constriction by local nitric oxide: onset during rapid juvenile growth. Microvasc Res 56: 192-202, 1998.
37. Macefield VG, Wallin BG, Vallbo AB. The discharge behaviour of single vasoconstrictor motoneurones in human muscle nerves. J Physiol 481: 799-809, 1994.
38. Martin WH, 3rd Tolley TK, Saffitz JE. Autoradiographic delineation of skeletal muscle alpha1-adrenergic receptor distribution. Am J Physiol Heart Circ Physiol 259: H1402-H1408, 1990.
39. McAllister RM, Laughlin MH. Short-term exercise training alters responses of porcine femoral and brachial arteries. J Appl Physiol 82: 1438-1444, 1997.
40. Murai H, Takata S, Maruyama M, Nakano M, Kobayashi D, Otowa K, Takamura M, Yuasa T, Sakagami S, Kaneko S. The activity of a single muscle sympathetic vasoconstrictor nerve unit is affected by physiological stress in humans. Am J Physiol Heart Circ Physiol 290: H853-H860, 2006.
41. Ng AV, Callister R, Johnson DG, Seals DR. Endurance exercise training is associated with elevated basal sympathetic nerve activity in healthy older humans. J Appl Physiol 77: 1366-1374, 1994.
42. Nilsson H, Ljung B, Sjoblom N, Wallin BG. The influence of the sympathetic impulse pattern on contractile responses of rat mesenteric arteries and veins. Acta Physiol Scand 123: 303-309, 1985.
43. Pernow J, Kahan T, Lundberg JM. Neuropeptide Y and reserpine-resistant vasoconstriction evoked by sympathetic nerve stimulation in the dog skeletal muscle. Br J Pharmacol 94: 952-960, 1988.
44. Revington M, McCloskey DI. Neuropeptide Y and control of vascular resistance in skeletal muscle. Regul Pept 23: 331-342, 1988.
45. Rowell LB. Human Cardiovascular Control. New York: Oxford University Press, 1993.
46. Samora JB, Frisbee JC, Boegehold MA. Growth-dependent changes in endothelial factors regulating arteriolar tone. Am J Physiol Heart Circ Physiol 292: H207-H214, 2007.
47. Sheldahl LM, Ebert TJ, Cox B, Tristani FE. Effect of aerobic training on baroreflex regulation of cardiac and sympathetic function. J Appl Physiol 76: 158-165, 1994.
48. Sinoway L, Shenberger J, Leaman G, Zelis R, Gray K, Baily R, Leuen-berger U. Forearm training attenuates sympathetic responses to prolonged rhythmic forearm exercise. J Appl Physiol 81: 1778-1784, 1996.
49. Spier SA, Laughlin MH, Delp MD. Effects of acute and chronic exercise on vasoconstrictor responsiveness of rat abdominal aorta. J Appl Physiol 87: 1752-1757, 1999.
50. Srere PA. Citrate synthase. Methods Enzymol 13: 3-5, 1969.
51. Sugawara J, Komine H, Hayashi K, Yoshizawa M, Otsuki T, Shimojo N, Miyauchi T, Yokoi T, Maeda S, Tanaka H. Systemic alpha-adren-ergic and nitric oxide inhibition on basal limb blood flow: effects of endurance training in middle-aged and older adults. Am J Physiol Heart Circ Physiol 293: H1466-H1472, 2007.
52. Sun D, Huang A, Koller A, Kaley G. Short-term daily exercise activity enhances endothelial NO synthesis in skeletal muscle arterioles of rats. J Appl Physiol 76: 2241-2247, 1994.
53. Tinken TM, Thijssen DH, Hopkins N, Dawson EA, Cable NT, Green DJ. Shear stress mediates endothelial adaptations to exercise training in humans. Hypertension 55: 312-318, 2010.
54. Tuttle JL, Nachreiner RD, Bhuller AS, Condict KW, Connors BA, Herring BP, Dalsing MC, Unthank JL. Shear level influences resistance artery remodeling: wall dimensions, cell density, and eNOS expression. Am J Physiol Heart Circ Physiol 281: H1380-H1389, 2001.
55. Wiegman DL, Harris PD, Joshua IG, Miller FN. Decreased vascular sensitivity to norepinephrine following exercise training. J Appl Physiol 51: 282-287, 1981.
56. Wray DW, Witman MA, Ives SJ, McDaniel J, Fjeldstad AS, Trinity JD, Conklin JD, Supiano MA, Richardson RS. Progressive handgrip exercise: evidence of nitric oxide-dependent vasodilation and blood flow regulation in humans. Am J Physiol Heart Circ Physiol 300: H1101-H1107, 2011.