Effects of acute and chronic exercise on vasoconstrictor responsiveness of rat abdominal aorta

Journal of Applied Physiology

Volumn 87, Issue 5, 1999, Pages 1752-1757

  Spier, Scott A ^a   Laughlin, M Harold ^b   Delp, Michael D ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

Exercise; Norepinephrine; Vascular smooth muscle

Indexed keywords

ARGIPRESSIN; NORADRENALIN; OXIDOREDUCTASE; PHENYLEPHRINE; POTASSIUM CHLORIDE; VASOCONSTRICTOR AGENT;

ABDOMINAL AORTA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; ENZYME ACTIVITY; EXERCISE; EXHAUSTION; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TENSION; TREADMILL EXERCISE; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

EID: 0032753776     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1999.87.5.1752     Document Type: Article

References (21)

1. Bennet, T., R. G. Wilcox, and I. A. MacDonald. Post-exercise reduction of blood pressure in hypertensive men is not due to acute impairment of baroreflex function. Clin. Sci. (Colch.) 67: 97-103, 1984.
2. Chen, H.-I., H.-T. Li, and C.-C. Chen. Physical conditioning decreases norepinephrine-induced vasoconstriction in rabbits: possible roles of norepinephrine-evoked endothelium-derived relaxing factor. Circulation 90: 970-975, 1994.
3. Coats, A. J. S., J. Conway, J. E. Isea, G. Pannarale, P. Sleight, and V. K. Somers. Systemic and forearm vascular resistance changes after upright bicycle exercise in man. J. Physiol. (Lond.) 413: 289-298, 1989.
4. Delp, M. D. Differential effects of training on the control of skeletal muscle perfusion. Med. Sci. Sports Exerc. 30: 361-364, 1998.
5. Delp, M. D., and M. H. Laughlin. Time course of enhanced endothelium-mediated dilation in aorta of trained rats. Med. Sci. Sports Exerc. 29: 1454-1461, 1997.
6. Delp, M. D., R. M. McAllister, and M. H. Laughlin. Exercise training alters endothelium-dependent vasoreactivity of rat abdominal aorta. J. Appl. Physiol. 75: 1354-1363, 1993.
7. Delp, M. D., R. M. McAllister, and M. H. Laughlin. Exercise training alters aortic vascular reactivity in hypothyroid rats. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H1428-H1435, 1995.
8. Fitzgerald, W. Labile hypertension and jogging: new diagnostic tool or spurious discovery? Br. Med. J. 282: 542-544, 1981.
9. Howard, M. G., and S. E. DiCarlo. Reduced vascular responsiveness after a single bout of dynamic exercise in the conscious rabbit. J. Appl. Physiol. 73: 2662-2667, 1992.
10. Howard, M. G., S. E. DiCarlo, and J. N. Stallone. Acute exercise attenuates phenylephrine-induced contraction of rabbit isolated aortic rings. Med. Sci. Sports Exerc. 24: 1102-1107, 1992.
11. Kaufman, F. L., R. L. Hughson, and J. P. Schaman. Effect of exercise on recovery blood pressure in normotensive and hypertensive subjects. Med. Sci. Sports Exerc. 19: 17-20, 1987.
12. Nadaud, S., M. Philippe, J.-F. Arnal, J.-B. Michel, and F. Soubrier. Sustained increase in aortic endothelial nitric oxide synthase expression in vivo in a model of chronic high blood flow. Circ. Res. 79: 857-863, 1996.
13. Overton, J. M., M. J. Joyner, and C. M. Tipton. Reductions in blood pressure after acute exercise by hypertensive rats. J. Appl. Physiol. 64: 748-752, 1988.
14. Piepoli, M., A. J. S. Coats, S. Adamopoulos, L. Bernardi, Y. H. Feng, J. Conway, and P. Sleight. Persistent peripheral vasodilation and sympathetic activity in hypotension after maximal exercise. J. Appl. Physiol. 75: 1807-1814, 1993.
15. Sessa, W. C., K. Pritchard, N. Seyedi, J. Wang, and T. H. Hintze. Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ. Res. 74: 349-353, 1994.
16. Srere, P.A. Citrate synthase. Methods Enzymol. 13: 3-5, 1969.
17. 2-adrenoreceptors and endothelium-derived relaxing factor. Am. J. Med. 87: 3C-1S, 1989.
18. VanNess, J. M., H. J. Takata, and J. M. Overton. Attenuated blood pressure responsiveness during post-exercise hypotension. Clin. Exp. Hypertens. 18: 891-900, 1996.
19. Weigman, D. L., P. D. Harris, I. G. Joshua, and F. N. Miller. Decreased vascular sensitivity to norepinephrine following exercise training. J. Appl. Physiol. 51: 282-287, 1981.
20. Wilcox, R. G., T. Bennet, A. M. Brown, and I.A. MacDonald. Is exercise good for high blood pressure? Br Med. J. 285: 767-769, 1982.
21. Woodman, C. R., J. M. Muller, M. H. Laughlin, and E. M. Price. Induction of nitric oxide synthase mRNA in coronary resistance arteries from exercise-trained pigs. Am. J. Physiol. 273 (Heart Circ. Physiol. 42): H2575-H2579, 1997.