Early pathogenesis of classical swine fever virus (CSFV) strains in Danish pigs

Veterinary Microbiology

Volumn 159, Issue 3-4, 2012, Pages 327-336

  Lohse, Louise ^a   Nielsen, Jens ^a   Uttenthal, Åse ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Clinical score; CSFV; Host virus interaction; Pathogenesis; Pathological score; Pig; Strain difference; Virus distribution

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENMARK; DISEASE SEVERITY; EARLY DIAGNOSIS; ENVIRONMENTAL FACTOR; FEVER; GASTROINTESTINAL DISEASE; HOST PATHOGEN INTERACTION; INOCULATION; LABORATORY DIAGNOSIS; LYMPH NODE; LYMPHOID TISSUE; NONHUMAN; PERSISTENT VIRUS INFECTION; PESTIVIRUS; PESTIVIRUS INFECTION; RISK ASSESSMENT; SWINE; SYMPTOM; TONSIL; VIRUS LOAD; VIRUS PATHOGENESIS; VIRUS STRAIN; VIRUS VIRULENCE;

ANIMALS; CLASSICAL SWINE FEVER; CLASSICAL SWINE FEVER VIRUS; DISEASE OUTBREAKS; PALATINE TONSIL; SUS SCROFA; SWINE; VIRAL LOAD; VIRULENCE; WEANING;

CLASSICAL SWINE FEVER VIRUS; SUIDAE;

EID: 84865625372     PISSN: 03781135     EISSN: 18732542     Source Type: Journal    
DOI: 10.1016/j.vetmic.2012.04.026     Document Type: Article

References (32)

1. {star, open}. Vet. Microbiol. 2000, 77:83-97.
2. Belak K., Koenen F., Vanderhallen H., Mittelholzer C., Feliziani F., De Mia G.M., Belak S. Comparative studies on the pathogenicity and tissue distribution of three virulence variants of classical swine fever virus, two field isolates and one vaccine strain, with special regard to immunohistochemical investigations. Acta Vet. Scand. 2008, 50:34.
3. Blacksell S.D., Khounsy S., Van A.D., Gleeson L.J., Westbury H.A. Comparative susceptibility of indigenous and improved pig breeds to Classical swine fever virus infection: practical and epidemiological implications in a subsistence-based, developing country setting. Trop. Anim. Health Prod. 2006, 38:467-474.
4. Depner K.R., Hinrichs U., Bickhardt K., Greiser-Wilke I., Pohlenz J., Moennig V., Liess B. Influence of breed-related factors on the course of classical swine fever virus infection. Vet. Rec. 1997, 140:506-507.
5. Donahue B.C., Petrowski H.M., Melkonian K., Ward G.B., Mayr G.A., Metwally S. Analysis of clinical samples for early detection of classical swine fever during infection with low, moderate, and highly virulent strains in relation to the onset of clinical signs. J. Virol. Methods 2012, 179:108-115.
6. Durand B., Davila S., Cariolet R., Mesplède A., Le Potier M.-F. Comparison of viraemia- and clinical-based estimates of within- and between-pen transmission of classical swine fever virus from three transmission experiments. Vet. Microbiol. 2009, 135:196-204.
7. Elbers A.R., Stegeman A., Moser H., Ekker H.M., Smak J.A., Pluimers F.H. The classical swine fever epidemic 1997-1998 in the Netherlands: descriptive epidemiology. Prev. Vet. Med. 1999, 42:157-184.
8. Elbers A.R.W., Vos J.H., Bouma A., van Exsel A.C.A., Stegeman A. Assessment of the use of gross lesions at post-mortem to detect outbreaks of classical swine fever. Vet. Microbiol. 2003, 96:345-356.
9. Elbers A.R.W., Gorgievski-Duijvesteijn M.J., van der Velden P.G., Loeffen W.L.A., Zarafshani K. A socio-psychological investigation into limitations and incentives concerning reporting a clinically suspect situation aimed at improving early detection of classical swine fever outbreaks. Vet. Microbiol. 2010, 142:108-118.
10. Elbers A., van der Gaag L., Schmeiser S., Uttenthal Å., Lohse L., Nielsen J., Crooke H., Blome S., Loeffen W. A Bayesian clinical decision support system for early detection of classical swine fever in individual pigs - evaluation of the sensitivity and specificity of the model. Proceedings of 8th ESVV Pestivirus Symposium 2011.
11. Everett H., Salguero F.J., Graham S.P., Haines F., Johns H., Clifford D., Nunez A., La Rocca S.A., Parchariyanon S., Steinbach F., Drew T., Crooke H. Characterization of experimental infections in domestic pigs with genotype 2.1 and 3.3 isolates of classical swine fever virus. Vet. Microbiol. 2010, 142:26-33.
12. Floegel-Niesmann G., Bunzenthal C., Fischer S., Moennig V. Virulence of recent and former classical swine fever isolates evaluated by their clinical and pathological signs. J. Vet. Med. B 2003, 50:214-220.
13. Floegel-Niesmann G., Blome S., Gerß-Dülmer H., Bunzenthal C., Moennig V. Virulence of classical swine fever virus isolates from Europe and other areas during 1996 until 2007. Vet. Microbiol. 2009, 139:165-169.
14. Fritzemeyer J., Teuffert J., Greiser-Wilke I., Staubach C., Schlüter H., Moennig V. Epidemiology of classical swine fever in Germany in the 1990s. Vet. Microbiol. 2000, 77:29-41.
15. Handel K., Kehler H., Hills K., Pasick J. Comparison of reverse transcriptase-polymerase chain reaction, virus isolation, and immunoperoxidase assays for detecting pigs infected with low, moderate, and high virulent strains of classical swine fever virus. J. Vet. Diagn. Invest. 2004, 16:132-138.
16. Hansen M.S., Bille-Hansen V., Uttenthal Å., Lohse L., Nielsen J. Localization of classical swine fever virus (CSFV) in the brain of pigs infected with strain Kozlov. Proceedings of 8th ESVV Pestivirus Symposium 2011.
17. Have P. Detection of antibodies against swine fever virus by enzyme-linked immunosorbent assay (ELISA). Acta Vet. Scand. 1984, 25:462-465.
18. Hyera J.M., Liess B., Frey H.R. A direct neutralizing peroxidase-linked antibody assay for detection and titration of antibodies to bovine viral diarrhea virus. Zbl. Vet. Med. B 1987, 34:227-239.
19. Kaden V., Lange E., Polster U., Klopfleisch R., Teifke J.P. Studies on the virulence of two field isolates of the classical swine fever virus genotype 2.3 Rostock in wild boars of different age groups. J. Vet. Med. 2004, 51:202-208.
20. Koenen F., Van Caenegem G., Vermeersch J.P., Vandenheede J., Deluyker H. Epidemiological characteristics of an outbreak of classical swine fever in an area of high pig density. Vet. Rec. 1996, 139:367-371.
21. Mayer D., Thayer T.M., Hofmann M.A., Tratschin J.D. Establishment and characterization of two cDNA-derived strains of classical swine fever virus, one highly virulent and one avirulent. Vet. Res. 2003, 98:105-116.
22. Meyer H., Liess B., Frey H.-R., Hermanns W., Trautwein G. Experimental transplacental transmission of hog cholera virus in pigs. IV. Virological and serological studies in newborn pigs. Zbl. Vet. Med. B 1981, 28:659-668.
23. Mittelholzer C., Moser C., Tratschin J.D., Hofmann M.A. Analysis of classical swine fever virus replication kinetics allows differentiation of highly virulent from avirulent strains. Vet. Microbiol. 2000, 74:293-308.
24. Moennig V., Floegel-Niesmann G., Greiser-Wilke I. Clinical signs and epidemiology of classical swine fever: a review of new knowledge. Vet. J. 2003, 165:11-20.
25. Nielsen J., Lohse L., Rasmussen T.B., Uttenthal Å. Classical swine fever in 6- and 11-week-old pigs: haematological and immunological parameters are modulated in pigs with mild clinical disease. Vet. Immunol. Immunopathol. 2010, 138:159-173.
26. Pol F., Rossi S., Mesplède A., Kuntz-Simon G., Le Potier M.F. Two outbreaks of classical swine fever in wild boar in France. Vet. Rec. 2008, 162:811-816.
27. Rasmussen T.B., Uttenthal Å., Reimann I., Nielsen J., Depner K., Beer M. Virulence, immunogenicity and vaccine properties of a novel chimeric pestivirus. J. Gen. Virol. 2007, 88:481-486.
28. Sandvik T., Drew T., Paton D. CSF virus in East Anglia: where from?. Vet. Rec. 2000, 147:251.
29. Uttenthal A., Storgaard T., Oleksiewicz M.B., de Stricker K. Experimental infection with the Paderborn isolate of classical swine fever virus in 10-week-old pigs: determination of viral replication kinetics by quantitative RT-PCR, virus isolation and antigen ELISA. Vet. Microbiol. 2003, 92:197-212.
30. Uttenthal A., Rasmussen T.B., Nielsen J. Classical swine fever in one-week-old piglets. Proceedings of the 7th ESSV Pestivirus Symposium 2008, 125.
31. Van Oirschot J.T., Terpstra C. A congenital persistent swine fever infection. I. Clinical and virological observations. Vet. Microbiol. 1977, 2:121-132.
32. Yadin H., Deike S., David D., Bombarov V., Fridgout O., Elad D., Brener Y., Edri N., Hadany Y., Perl S. Case study - occurrence of classical swine fever in Israel. Abstract in Report on Annual Meeting of National Swine Fever Laboratories 2009.