Effects of interventions on depression in heart failure: A systematic review

Heart and Lung: Journal of Acute and Critical Care

Volumn 41, Issue 5, 2012, Pages 469-483

  Woltz, Patricia C ^a,b   Chapa, Deborah W ^c   Friedmann, Erika ^b   Son, Heesook ^c   Akintade, Bimbola ^b   Thomas, Sue Ann ^b  

^a UNIVERSITY OF MARYLAND MEDICAL CENTER   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF NURSING   (United States)

^c GEORGE WASHINGTON UNIVERSITY   (United States)

Author keywords

Depression; Heart failure; Intervention; Systematic review

Indexed keywords

CITALOPRAM; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; PAROXETINE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE;

ALTERNATIVE MEDICINE; ANEMIA; COGNITIVE THERAPY; DEPRESSION; EXERCISE; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; MUSCLE RELAXATION; PATIENT CARE; PRIORITY JOURNAL; RESISTANCE TRAINING; REVIEW; STRESS MANAGEMENT; SUICIDAL IDEATION; SYSTEMATIC REVIEW; TAI CHI; UNSPECIFIED SIDE EFFECT; WALKING; WEIGHT CONTROL;

ANTIDEPRESSIVE AGENTS; DEPRESSION; HEART FAILURE; HUMANS; TREATMENT OUTCOME;

EID: 84865608578     PISSN: 01479563     EISSN: 15273288     Source Type: Journal    
DOI: 10.1016/j.hrtlng.2012.06.002     Document Type: Review

References (83)

1. Thomas S.A., Chapa D.W., Friedmann E., Durden C., Ross A., Lee M.C., et al. Depression in patients with heart failure: prevalence, pathophysiological mechanisms, and treatment. Crit Care Nurse 2008, 28:40-55.
2. Parissis J.T., Fountoulaki K., Paraskevaidis I., Kremastinos D. Depression in chronic heart failure: novel pathophysiological mechanisms and therapeutic approaches. Expert Opin Invest Drugs 2005, 14:567-577.
3. Evans D.L., Charney D.S., Lewis L., Golden R.N., Gorman J.M., Krishnan K.R., et al. Mood disorders in the medically ill: scientific review and recommendations. Biol Psychiatry 2005, 58:175-189.
4. Sullivan M., Levy W.C., Russo J.E., Spertus J.A. Depression and health status in patients with advanced heart failure: a prospective study in tertiary care. J Card Fail 2004, 10:390-396.
5. Rumsfeld J.S., Havranek E., Masoudi F.A., Peterson E.D., Jones P., Tooley J.F., et al. Depressive symptoms are the strongest predictors of short-term declines in health status in patients with heart failure. J Am Coll Cardiol 2003, 42:1811-1817.
6. Jiang W., Alexander J., Christopher E., Kuchibhatla M., Gaulden L.H., Cuffe M.S., et al. Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure. Arch Intern Med 2001, 161:1849-1856.
7. Faris R., Purcell H., Henein M.Y., Coats A.J. Clinical depression is common and significantly associated with reduced survival in patients with non-ischemic heart failure. Eur J Heart Fail 2002, 4:541-551.
8. Jiang W., Kuchibhatla M., Cuffe M.S., Christopher E.J., Alexander J.D., Clary G.L., et al. Prognostic value of anxiety and depression in patients with chronic heart failure. Circulation 2004, 110:3452-3456.
9. Sayers S.L., Hanrahan N., Kutney A., Clarke S.P., Reis B.F., Riegel B. Psychiatric comorbidity and greater hospitalization risk, longer length of stay, and higher hospitalization costs in older adults with heart failure. J Am Geriatr Soc 2007, 55:1585-1591.
10. Fulop G., Strain J.J., Stettin G. Congestive heart failure and depression in older adults: clinical course and health services use 6 months after hospitalization. Psychosomatics 2003, 44:367-373.
11. Diagnostic and statistical manual of mental disorders-4th ed (DSM-IV) and text-revision (DSM-IV-TR) 2000, American Psychiatric Association, American Psychiatric Association Press, Washington, DC.
12. Handbook of chronic depression 2004, Marcel Dekker, Inc, New York. J.E. Alpert, M. Fava (Eds.).
13. Jacob S., Sebastian J.C., Abraham G. Depression and congestive heart failure: are antidepressants underutilized?. Eur J Heart Fail 2003, 5:399-400.
14. Gottlieb S.S., Kop W.J., Ellis S.J., Binkley P., Howlett J., O'Connor C., et al. Relation of depression to severity of illness in heart failure (from Heart Failure and a Controlled Trial Investigating Outcomes of Exercise Training [HF-ACTION]). Am J Cardiol 2009, 103:1285-1289.
15. Redeker N.S. Somatic symptoms explain differences in psychological distress in heart failure patients vs a comparison group. Prog Cardiovasc Nurs 2006, 21:182-189.
16. Liberati A., Altman D.G., Tetzlaff J., Mulrow C., Gøtzsche P.C., Ioannidis J.P., et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol 2009, 62:e1-34.
17. Moher D., Liberati A., Tetzlaff J., Altman D.G. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol 2009, 62:1006-1012. for the PRISMA Group.
18. Lane D.A., Chong A.Y., Lip G.Y. Psychological interventions for depression in heart failure. Cochrane Database Syst Rev 2005, 1:CD003329.
19. Appendix 9: search strategies for the identification of clinical studies. British Psychological Society and Royal College of Psychiatrists, editor. NICE clinical practice guideline 115: alcohol-use disorders: diagnosis, assessment and management of harmful drinking and alcohol dependence 2011, NICE and National Collaborating Center for Mental Health, British Psychological Society and Royal College of Psychiatrists, London, Available at:, Accessed August 25, 2011. http://www.nice.org.uk/nicemedia/live/13337/55724/55724.pdf.
20. Berlin J.A. Does blinding of readers affect the results of meta-analyses?. Lancet 1997, 350:185-186.
21. Effective Public Health Practice Project. Quality assessment tool for quantitative studies. 1998. Available at: Accessed October 2011. http://www.ephpp.ca/index.html.
22. Thomas B.H., Ciliska D., Dobbins M., Micucci S. A process for systematically reviewing the literature: providing the research evidence for public health nursing interventions. Worldviews Evid Based Nurs 2004, 1:176-184.
23. Deeks J.J., Dinnes J., D'Amico R., Sowden A.J., Sakarovitch C., Song F., et al. Evaluating non-randomized intervention studies. Health Technol Assess 2003, 7:1-192.
24. Atkins D., Best D., Briss P.A., Eccles M., Falck-Ytter Y., Flottorp S., et al. Grading quality of evidence and strength of recommendations. Br Med J [Clin Res] 2004, 328:1490-1494.
25. Miche E., Roelleke E., Zoller B., Wirtz U., Schneider M., Huerst M., et al. A longitudinal study of quality of life in patients with chronic heart failure following an exercise training program. Eur J Cardiovasc Nurs 2009, 8:281-287.
26. Owens D.K., Lohr K.N., Atkins D., Treadwell J.R., Reston J.T., Bass E.B., et al. AHRQ series paper 5: grading the strength of a body of evidence when comparing medical interventions: agency for healthcare research and quality and the effective health-care program. J Clin Epidemiol 2010, 63:513-523.
27. Owens DK, Lohr KN, Atkins D, Treadwell JR, Reston JT, Bass EB, et al. Grading the strength of a body of evidence when comparing medical interventions. In: AHRQ methods guide for comparative effectiveness reviews. 2009:1-15. Available at: Accessed October 15, 2011. http://effectivehealthcare.ahrq.gov/healthInfo.cfm%3Finfotype%3Drr%26ProcessID%3D60.
28. National Center for Complementary and Alternative Medicine. What is complementary and alternative medicine? NCCAM publication no. D347. July 2012. Available at: Accessed September 3, 2011. http://nccam.nih.gov/health/whatiscam.
29. Raman G, DeVine D, Lau J. Technology assessment: non-pharmacological interventions for post-discharge care in heart failure. 2008. Available at: Accessed October 3, 2011. http://www.ahrq.gov/clinic/ta/hospdischrg/hospdis2.htm.
30. O'Connor C.M., Jiang W., Kuchibhatla M., Silva S.G., Cuffe M.S., Callwood D.D., et al. Safety and efficacy of sertraline for depression in patients with heart failure: results of the SADHART-CHF (Sertraline Against Depression and Heart Disease in Chronic Heart Failure) Trial. J Am Coll Cardiol 2010, 56:692-699.
31. Lekakis J., Ikonomidis I., Papoutsi Z., Moutsatsou P., Nikolaou M., Parissis J., et al. Selective serotonin re-uptake inhibitors decrease the cytokine-induced endothelial adhesion molecule expression, the endothelial adhesiveness to monocytes and the circulating levels of vascular adhesion molecules. Int J Cardiol 2010, 139:150-158.
32. Kourea K., Parissis J.T., Farmakis D., Paraskevaidis I., Panou F., Filippatos G., et al. Effects of darbepoetin-alpha on quality of life and emotional stress in anemic patients with chronic heart failure. Eur J Cardiovasc Prev Rehabil 2008, 15:365-369.
33. Dracup K., Evangelista L.S., Hamilton M.A., Erickson V., Hage A., Moriguchi J., et al. Effects of a home-based exercise program on clinical outcomes in heart failure. Am Heart J 2007, 154:877-883.
34. Kulcu D.G., Kurtais Y., Tur B.S., Gulec S., Seckin B. The effect of cardiac rehabilitation on quality of life, anxiety and depression in patients with congestive heart failure: a randomized controlled trial, short term results. Eur Medicophys 2007, 43:489-497.
35. Jolly K., Taylor R.S., Lip G.Y., Davies M., Davis R., Mant J., et al. A randomized trial of the addition of home-based exercise to specialist heart failure nurse care: the Birmingham Rehabilitation Uptake Maximisation Study for Patients With Congestive Heart Failure (BRUM-CHF) Study. Eur J Heart Fail 2009, 11:205-213.
36. Karapolat H., Demir E., Bozkaya Y.T., Eyigor S., Nalbantgil S., Durmaz B., et al. Comparison of hospital-based versus home-based exercise training in patients with heart failure: effects on functional capacity, quality of life, psychological symptoms, and hemodynamic parameters. Clin Res Cardiol 2009, 98:635-642.
37. Yu D.S., Lee D.T., Woo J., Hui E. Non-pharmacological interventions in older people with heart failure: effects of exercise training and relaxation therapy. Gerontology 2007, 53:74-81.
38. Radzewitz A., Miche E., Herrmann G., Nowak M., Montanus U., Adam U., et al. Exercise and muscle strength training and their effects on quality of life in patients with chronic heart failure. Eur J Heart Fail 2002, 4:627-634.
39. Schwarz K.A., Mion L.C., Hudock D., Litman G. Telemonitoring of heart failure patients and their caregivers: a pilot randomized controlled trial. Prog Cardiovasc Nurs 2008, 23:18-26.
40. Riegel B., Carlson B., Glaser D., Romero T. Randomized controlled trial of telephone case management in Hispanics of Mexican origin with heart failure. J Card Fail 2006, 12:211-219.
41. Dunagan W.C., Littenberg B., Ewald G.A., Jones C.A., Emery V.B., Waterman B.M., et al. Randomized trial of a nurse-administered, telephone-based disease management program for patients with heart failure. J Card Fail 2005, 11:358-365.
42. Azad N., Molnar F., Byszewski A. Lessons learned from a multidisciplinary heart failure clinic for older women: a randomized controlled trial. Age Ageing 2008, 37:282-287.
43. Barrow D.E., Bedford A., Ives G., O'Toole L., Channer K.S. An evaluation of the effects of tai chi chuan and chi kung training in patients with symptomatic heart failure: a randomized controlled pilot study. Postgrad Med J 2007, 83:717-721.
44. Sullivan M.J., Wood L., Terry J., Brantley J., Charles A., McGee V., et al. The Support, Education, and Research in Chronic Heart Failure Study (SEARCH): a mindfulness-based psycho educational intervention improves depression and clinical symptoms in patients with chronic heart failure. Am Heart J 2009, 157:84-90.
45. Gary R.A., Dunbar S.B., Higgins M.K., Musselman D.L., Smith A.L. Combined exercise and cognitive behavioral therapy improves outcomes in patients with heart failure. J Psychosom Res 2010, 69:119-131.
46. Fraguas R., da Silva Telles R.M., Alves T.C., Andrei A.M., Rays J., Iosifescu D.V., et al. A double-blind, placebo-controlled treatment trial of citalopram for major depressive disorder in older patients with heart failure: the relevance of the placebo effect and psychological symptoms. Contemp Clin Trials 2009, 30:205-211.
47. Mårtensson J., Strömberg A., Dahlström U., Karlsson J.E., Fridlund B. Patients with heart failure in primary health care: effects of a nurse-led intervention on health-related quality of life and depression. Eur J Heart Fail 2005, 7:393-403.
48. Andryukhin A., Frolova E., Vaes B., Degryse J. The impact of a nurse-led care programme on events and physical and psychosocial parameters in patients with heart failure with preserved ejection fraction: a randomized clinical trial in primary care in Russia. Eur J Gen Pract 2010, 16:205-214.
49. Gottlieb S.S., Kop W.J., Thomas S.A., Katzen S, Vesely MR, Greenberg N, et al. A double-blind placebo-controlled pilot study of controlled-release paroxetine on depression and quality of life in chronic heart failure. Am Heart J 2007, 153:868-873.
50. Powell L.H., Calvin J.E., Richardson D., Janssen I., Mendes de Leon C.F., Flynn K.J., et al. Self-management counseling in patients with heart failure. JAMA 2010, 304:1331.
51. Yeh G.Y., McCarthy E.P., Wayne P.M., Stevenson L.W., Wood M.J., Forman D., et al. Tai chi exercise in patients with chronic heart failure: a randomized clinical trial. Arch Intern Med 2011, 171:750.
52. Cohen J. Statistical power analysis for the behavioral sciences 1988, Erlbaum, Hillsdale, NJ. 2nd ed.
53. Grissom R.J., Kim J.J. Effect sizes for research: univariate and multivariate applications 2012, Taylor & Francis Group, New York. 2nd ed.
54. Lane DM. HyperStat online statistics textbook. 2007. Available at: Accessed April 19, 2012. http://davidmlane.com/hyperstat/effect_size.html.
55. Atkins D., Eccles M., Flottorp S., et al. Systems for grading the quality of evidence and the strength of recommendations I: critical appraisal of existing approaches: the GRADE Working Group. BMC Health Serv Res 2004, 4:38.
56. Hartling L., Bond B., Harvey K., Santaguida P., Viswananthan M., Dryden D. Developing and testing a tool for the classification of study designs in systematic reviews of interventions and exposures. AHRQ publication no. 11-EHC-007 2010, Agency for Healthcare Research and Quality, Rockville, MD, Available at:, Accessed March 5, 2012. http://effectivehealthcare.ahrq.gov/.
57. Pfeffer M.A., Burdmann E.A., Chen C.Y., Cooper M.E., de Zeeuw D., Eckardt K.U., et al. A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease. N Engl J Med 2009, 361:2019-2032.
58. United States Food and Drug Administration. Postmarket drug safety information for patients and providers: information on erythropoiesis-stimulating agents (ESA) epoetin alfa (marketed as Procrit, Epogen), darbepoetin alfa (marketed as Aranesp). 2011. Available at: Accessed November 3, 2011. http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm109375.htm.
59. Velasco-Garrido M, Busse R, Hisashige A. Are disease management programmers (DMPs) effective in improving quality of care for people with chronic conditions? Health Evidence Network report. 2003. Available at: Accessed November 17, 2011. http://www.euro.who.int/document/e82974.pdf.
60. Hunt S.A., Baker D.W., Chin M.H., Cinquegrani M.P., Feldman A.M., Francis G.S., et al. ACC/AHA practice guidelines. Circulation 2001, 104:2996-3007.
61. Hunt S.A., Abraham W.T., Chin M.H., Feldman A.M., Francis G.S., Ganiats T.G., et al. ACC/AHA 2005 guideline update for the diagnosis and management of chronic heart failure in the adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 2005, 112:e154-e235.
62. Nonpharmacologic management and health care maintenance in patients with chronic heart failure. J Card Fail 2006, 12:e29-e37. Heart Failure Society of America.
63. Tierney S., Mamas M., Woods S., Rutter M.K., Gibson M., Neyses L., et al. What strategies are effective for exercise adherence in heart failure? A systematic review of controlled studies. Heart Fail Rev 2012, 17:107-115.
64. Whellan D.J., O'Connor C.M., Lee K.L., Keteyian S.J., Cooper L.S., Ellis S.J., et al. Heart Failure and a Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION): design and rationale. Am Heart J 2007, 153:201-211.
65. Flynn K.E., Piña I.L., Whellan D.J., Lin L., Blumenthal J.A., Ellis S.J., et al. Effects of exercise training on health status in patients with chronic heart failure: HF-ACTION randomized controlled trial. JAMA 2009, 301:1451-1459.
66. Guyatt G.H., Oxman A.D., Montori V., Vist G., Kunz R., Brozek J., et al. GRADE guidelines: 5. Rating the quality of evidence-publication bias. J Clin Epidemiol 2011, 64:1277-1282.
67. Pham B., Klassen T.P., Lawson M.L., Moher D. Language of publication restrictions in systematic reviews gave different results depending on whether the intervention was conventional or complementary. J Clin Epidemiol 2005, 58:769-776.
68. Vickers A., Goyal N., Harland R., Rees R. Do certain countries produce only positive results? A systematic review of controlled trials. Controlled Clin Trials 1998, 19:159.
69. Jayadevappa R., Johnson J.C., Bloom B.S., Nidich S., Desai S., Chhatre S., et al. Effectiveness of transcendental meditation on functional capacity and quality of life of African Americans with congestive heart failure: A randomized control study. Ethn Dis 2007, 17:72-77.
70. Luskin F., Newell K., Haskell W. Stress management training of elderly patients with congestive heart failure: pilot study. Prev Cardiol 1999, 2:101-104.
71. Luskin F., Reitz M., Newell K., Quinn T.G., Haskell W. A controlled pilot study of stress management training of elderly patients with congestive heart failure. Prev Cardiol 2002, 5:168-172.
72. Swanson K.S., Gevirtz R.N., Brown M., Spira J., Guarneri E., Stoletniy L. The effect of biofeedback on function in patients with heart failure. Appl Psychophysiol Biofeedback 2009, 34:71-91.
73. Cole S.A., Farber N.C., Weiner J.S., Sulfaro M., Katzelnick D.J., Blader J.C. Double-disease management or one care manager for two chronic conditions: pilot feasibility study of nurse telephonic disease management for depression and congestive heart failure. Dis Manag 2006, 9:266-276.
74. Delaney C., Apostolidis B. Pilot testing of a multicomponent home care intervention for older adults with heart failure: an academic clinical partnership. J Cardiovasc Nurs 2010, 25:E27-E40.
75. Gary R.A., Sueta C.A., Dougherty M., Rosenberg B., Cheek D., Preisser J., et al. Home-based exercise improves functional performance and quality of life in women with diastolic heart failure. Heart Lung 2004, 33:210-218.
76. Gary R. Exercise self-efficacy in older women with diastolic heart failure: results of a walking program and education intervention. J Gerontol Nurs 2006, 32:31-41.
77. Gottlieb S.S., Fisher M.L., Freudenberger R., Robinson S., Zietowski G., Alves L., et al. Effects of exercise training on peak performance and quality of life in congestive heart failure patients. J Card Fail 1999, 5:188-194.
78. Koukouvou G., Kouidi E., Iacovides A., Konstantinidou E., Kaprinis G., Deligiannis A. Quality of life, psychological and physiological changes following exercise training in patients with chronic heart failure. J Rehabil Med 2004, 36:36-41.
79. van den Berg-Emons R., Balk A., Bussmann H., Stam H. Does aerobic training lead to a more active lifestyle and improved quality of life in patients with chronic heart failure?. Eur J Heart Fail 2004, 6:95-100.
80. Witham M.D., Daykin A.R., McMurdo M.E. Pilot study of an exercise intervention suitable for older heart failure patients with left ventricular systolic dysfunction. Eur J Cardiovasc Nurs 2008, 7:303-306.
81. Hui E., Yang H., Chan L.S., Or K., Lee D.T., Yu C.M., et al. A community model of group rehabilitation for older patients with chronic heart failure: a pilot study. Disabil Rehabil 2006, 28:1491-1497.
82. Flynn K.J., Powell L.H., Mendes de Leon C.F., Muñoz R., Eaton C.B., Downs D.L., et al. Increasing self-management skills in heart failure patients: a pilot study. Congest Heart Fail 2005, 11:297-302.
83. Lespérance F., Frasure-Smith N., Laliberté M.A., White M., Lafontaine S., Calderone A., et al. An open-label study of nefazodone treatment of major depression in patients with congestive heart failure. Can J Psychiatry 2003, 48:695-701.