Trypanosoma cruzi carrying a monoallelic deletion of the calreticulin (TcCRT) gene are susceptible to complement mediated killing and defective in their metacyclogenesis

Molecular Immunology

Volumn 53, Issue 3, 2013, Pages 198-205

  Sánchez Valdéz, Fernando J ^a   Pérez Brandán, Cecilia ^a   Zago, M Paola ^a   Labriola, Carlos ^b   Ferreira, Arturo ^c   Basombrío, Miguel ángel ^a  

^a UNIVERSIDAD NACIONAL DE SALTA   (Argentina)

^b FUNDACIÓN INSTITUTO LELOIR   (Argentina)

^c UNIVERSITY OF CHILE   (Chile)

Author keywords

C1; Calreticulin; Complement mediate killing; Gene knock out; Gene overexpression; Trypanosoma cruzi

Indexed keywords

CALRETICULIN; COMPLEMENT COMPONENT C1;

ARTICLE; CELL KILLING; COMPLEMENT ACTIVATION; DOWN REGULATION; EPIMASTIGOTE; GENE DELETION; GENE EXPRESSION; GENE INACTIVATION; GENE OVEREXPRESSION; GENETIC SUSCEPTIBILITY; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; TRYPANOSOMA CRUZI; UPREGULATION;

ANIMALS; BASE SEQUENCE; CALRETICULIN; COMPLEMENT SYSTEM PROTEINS; CYTOTOXICITY, IMMUNOLOGIC; DNA, PROTOZOAN; GENE DELETION; GENES, PROTOZOAN; HUMANS; INSECT VECTORS; PROTOZOAN PROTEINS; TRIATOMA; TRYPANOSOMA CRUZI; UP-REGULATION;

TRYPANOSOMA CRUZI;

EID: 84865608125     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2012.08.001     Document Type: Article

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