Enhanced drug delivery capabilities from stents coated with absorbable polymer and crystalline drug

Journal of Controlled Release

Volumn 162, Issue 3, 2012, Pages 561-567

  Carlyle, Wenda C ^a   McClain, James B ^a   Tzafriri, Abraham R ^b,c   Bailey, Lynn ^b   Zani, Brett G ^b   Markham, Peter M ^b   Stanley, James R L ^b   Edelman, Elazer R ^c  

^a Micell Technologies Inc   (United States)

^b CBSET   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Crystalline; Modeling; Pharmacokinetic; PLGA; Sirolimus; Stent

Indexed keywords

ABSORBABLE POLYMERS; COATING MATERIAL; COMPUTATIONAL MODELING; DRUG RELEASE; DRUG STABILITY; DRUG-ELUTING STENTS; ELECTROSTATIC PROCESS; PLGA; PORCINE CORONARY ARTERY; SIROLIMUS; STENT; STENT COATINGS; STENT IMPLANTATION; TISSUE LEVELS;

COATINGS; COMPUTER SIMULATION; CRYSTALLINE MATERIALS; DRUG DELIVERY; DRUG PRODUCTS; EROSION; MODELS; OPTIMIZATION; PHARMACOKINETICS; STRUTS; TISSUE;

STENTS;

POLYGLACTIN; RAPAMYCIN;

ANIMAL TISSUE; ARTICLE; BARE METAL STENT; BIOCOMPATIBILITY; CONTROLLED STUDY; CORONARY ARTERY; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG ELUTING STENT; DRUG RELEASE; DRUG STABILITY; INFLAMMATION; MATERIAL COATING; NEOINTIMA; NONHUMAN; PRIORITY JOURNAL; SIMULATION; STATIC ELECTRICITY; STENOSIS; STENT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CONSTRICTION, PATHOLOGIC; CORONARY VESSELS; CRYSTALLIZATION; DRUG DELIVERY SYSTEMS; DRUG-ELUTING STENTS; LACTIC ACID; MODELS, BIOLOGICAL; NEOINTIMA; POLYGLYCOLIC ACID; POLYMERS; SIROLIMUS; SWINE; TUNICA MEDIA;

EID: 84865602524     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.07.004     Document Type: Article

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