Childhood-onset anti-MuSK antibody positive myasthenia gravis demonstrates a distinct clinical course

Brain and Development

Volumn 34, Issue 9, 2012, Pages 784-786

  Takahashi, Yumi ^a   Sugiyama, Minako ^b   Ueda, Yuki ^a   Itoh, Tomoshiro ^a   Yagyu, Kazuyori ^a   Shiraishi, Hideaki ^a   Ukeba Terashita, Yukayo ^b   Nakanishi, Masanori ^b   Nagashima, Tetsuro ^b   Imai, Tomihiro ^c   Motomura, Masakatsu ^d   Saitoh, Shinji ^a,e  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Kushiro Red Cross Hospital   (Japan)

^c SAPPORO MEDICAL UNIVERSITY   (Japan)

^d NAGASAKI UNIVERSITY   (Japan)

^e NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

Muscle specific tyrosine kinase; Myasthenia gravis; Seronegative myasthenia gravis

Indexed keywords

ANTIBIOTIC AGENT; IMMUNOGLOBULIN; METHYLPREDNISOLONE; MUSCLE SPECIFIC TYROSINE KINASE ANTIBODY; PREDNISONE; UNCLASSIFIED DRUG;

ANTIBODY PRODUCTION; ARTICLE; CASE REPORT; CHILD; CLINICAL FEATURE; DIPLOPIA; DISEASE COURSE; DISEASE SEVERITY; DYSPHAGIA; FEMALE; HUMAN; MYASTHENIA GRAVIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PNEUMONIA; PTOSIS; RESPIRATORY FAILURE; STRABISMUS; SYMPTOM; VIRUS INFECTION;

AUTOANTIBODIES; CHILD; DISEASE PROGRESSION; ELECTRIC STIMULATION; ELECTROMYOGRAPHY; FEMALE; HUMANS; MUSCLE, SKELETAL; MYASTHENIA GRAVIS; RECEPTOR PROTEIN-TYROSINE KINASES;

EID: 84865587059     PISSN: 03877604     EISSN: 18727131     Source Type: Journal    
DOI: 10.1016/j.braindev.2011.12.014     Document Type: Article

References (10)

1. Hoch W., McConville J., Newsom-Davis J., Melms A., Vincent A. Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies. Nat Med 2001, 7:365-368.
2. Deymeer F., Gungor-Tuncer O., Yilmaz V., Parman Y., Serdaroglu P., Ozdemir C., et al. Clinical comparison of anti-MuSK- vs anti-AChR-positive and seronegative myasthenia gravis. Neurology 2007, 68:609-611.
3. Evoli A., Bianchi M.R., Riso R., Minicuci G.M., Batocchi A.P., Servidei S., et al. Response to therapy in Myasthenia gravis with anti-MuSK antibodies. Ann NY Acad Sci 2008, 1132:76-83.
4. Murai H., Noda T., Himeno E., Kwano Y., Ohyagi Y., Shiraishi H., et al. Infantile onset myasthenia gravis with MuSK antibodies. Neurology 2006, 67:174.
5. Anlar B., Yilmaz V., Saruhan-Direskeneli G. Long remission in muscle-specific kinase antibody-positive juvenile myasthenia. Pediatr Neurol 2009, 40:455-456.
6. Chevessier F., Girard E., Molgo J., Bartling S., Koenig J., Hantai D., et al. A mouse model for congenital myasthenic syndrome due to MuSK mutations reveals defects in structure and function of neuromuscular junctions. Hum Mol Genet 2008, 17:3577-3595.
7. Benatar M., Hanmad M., Doss-Riney H. Concentric-needle single-fiber electromyography for the diagnosis of myasthenia gravis. Muscle Nerve 2006, 34:163-168.
8. Nemoto Y., Kuwabara S., Misawa S., Kawaguchi N., Hattori T., Takamori M., et al. Patterns and severity of neuromuscular transmission failure in seronegative myasthenia gravis. J Neurol Neurosurg Psychiatry 2005, 76:714-718.
9. Kouyoumdjian J.A., Stålberg E.V. Reference jitter values for concentric needle electrodes in voluntarily activated extensor digitorum communis and orbicularis oculi muscles. Muscle Nerve 2008, 37:694-699.
10. Bartoccioni E., Scuderi F., Minicuci G.M., Marino M., Ciaraffa F., Evoli A. Anti-MuSK antibodies: correlation with myasthenia gravis severity. Neurology 2006, 67:505-507.