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Volumn 47, Issue 5, 2012, Pages 645-654

Dose- and time-dependent effects of recombinant human bone morphogenetic protein-2 on the osteogenic and adipogenic potentials of alveolar bone-derived stromal cells

Author keywords

Adipogenesis; Osteogenesis; Recombinant human bone morphogenetic protein 2; Stem cells; Tissue engineering

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; BONE SIALOPROTEIN; HYDROXYAPATITE; HYDROXYAPATITE TRICALCIUMPHOSPHATE COMPOSITE; HYDROXYAPATITE-TRICALCIUMPHOSPHATE COMPOSITE; LIPOPROTEIN LIPASE; MESSENGER RNA; OSTEOCALCIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2; RECOMBINANT PROTEIN; TISSUE SCAFFOLD; TRANSFORMING GROWTH FACTOR BETA;

EID: 84865573010     PISSN: 00223484     EISSN: 16000765     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2012.01477.x     Document Type: Article
Times cited : (18)

References (39)
  • 1
    • 34250019537 scopus 로고
    • Bone: formation by autoinduction
    • Urist MR. Bone: formation by autoinduction. Science 1965;150:893-899.
    • (1965) Science , vol.150 , pp. 893-899
    • Urist, M.R.1
  • 2
    • 0038792833 scopus 로고    scopus 로고
    • Augmentation of alveolar bone and dental implant osseointegration: clinical implications of studies with rhBMP-2
    • Wikesjo UM, Sorensen RG, Wozney JM. Augmentation of alveolar bone and dental implant osseointegration: clinical implications of studies with rhBMP-2. J Bone Joint Surg Am 2001;83-A (Suppl 1):S136-S145.
    • (2001) J Bone Joint Surg Am , vol.83 A , Issue.SUPPL. 1
    • Wikesjo, U.M.1    Sorensen, R.G.2    Wozney, J.M.3
  • 4
    • 0035491139 scopus 로고    scopus 로고
    • Alveolar ridge augmentation with rhBMP-2 and bone-to-implant contact in induced bone
    • Sigurdsson TJ, Nguyen S, Wikesjo UM. Alveolar ridge augmentation with rhBMP-2 and bone-to-implant contact in induced bone. Int J Periodontics Restorative Dent 2001;21:461-473.
    • (2001) Int J Periodontics Restorative Dent , vol.21 , pp. 461-473
    • Sigurdsson, T.J.1    Nguyen, S.2    Wikesjo, U.M.3
  • 6
    • 0141681307 scopus 로고    scopus 로고
    • Long-term functional loading of dental implants in rhBMP-2 induced bone. A histologic study in the canine ridge augmentation model
    • Jovanovic SA, Hunt DR, Bernard GW et al. Long-term functional loading of dental implants in rhBMP-2 induced bone. A histologic study in the canine ridge augmentation model. Clin Oral Implants Res 2003;14:793-803.
    • (2003) Clin Oral Implants Res , vol.14 , pp. 793-803
    • Jovanovic, S.A.1    Hunt, D.R.2    Bernard, G.W.3
  • 8
    • 0036548656 scopus 로고    scopus 로고
    • Peri-implant bone regeneration using recombinant human bone morphogenetic protein-2 in a canine model: a dose-response study
    • Tatakis DN, Koh A, Jin L, Wozney JM, Rohrer MD, Wikesjo UM. Peri-implant bone regeneration using recombinant human bone morphogenetic protein-2 in a canine model: a dose-response study. J Periodontal Res 2002;37:93-100.
    • (2002) J Periodontal Res , vol.37 , pp. 93-100
    • Tatakis, D.N.1    Koh, A.2    Jin, L.3    Wozney, J.M.4    Rohrer, M.D.5    Wikesjo, U.M.6
  • 9
    • 2942655267 scopus 로고    scopus 로고
    • rhBMP-2 significantly enhances guided bone regeneration
    • Wikesjo UM, Qahash M, Thomson RC et al. rhBMP-2 significantly enhances guided bone regeneration. Clin Oral Implants Res 2004;15:194-204.
    • (2004) Clin Oral Implants Res , vol.15 , pp. 194-204
    • Wikesjo, U.M.1    Qahash, M.2    Thomson, R.C.3
  • 10
    • 0029249926 scopus 로고
    • Periodontal repair in dogs: recombinant human bone morphogenetic protein-2 significantly enhances periodontal regeneration
    • Sigurdsson TJ, Lee MB, Kubota K, Turek TJ, Wozney JM, Wikesjo UM. Periodontal repair in dogs: recombinant human bone morphogenetic protein-2 significantly enhances periodontal regeneration. J Periodontol 1995;66:131-138.
    • (1995) J Periodontol , vol.66 , pp. 131-138
    • Sigurdsson, T.J.1    Lee, M.B.2    Kubota, K.3    Turek, T.J.4    Wozney, J.M.5    Wikesjo, U.M.6
  • 11
    • 0034026950 scopus 로고    scopus 로고
    • Evaluation of recombinant human bone morphogenetic protein-2 as a bone-graft substitute in a canine segmental defect model
    • Sciadini MF, Johnson KD. Evaluation of recombinant human bone morphogenetic protein-2 as a bone-graft substitute in a canine segmental defect model. J Orthop Res 2000;18:289-302.
    • (2000) J Orthop Res , vol.18 , pp. 289-302
    • Sciadini, M.F.1    Johnson, K.D.2
  • 12
    • 79955022472 scopus 로고    scopus 로고
    • High doses of bone morphogenetic protein 2 induce structurally abnormal bone and inflammation in vivo
    • Zara JN, Siu RK, Zhang X et al. High doses of bone morphogenetic protein 2 induce structurally abnormal bone and inflammation in vivo. Tissue Eng Part A 2011;17:1389-1399.
    • (2011) Tissue Eng Part A , vol.17 , pp. 1389-1399
    • Zara, J.N.1    Siu, R.K.2    Zhang, X.3
  • 13
    • 79951936871 scopus 로고    scopus 로고
    • Enhanced adipogenic differentiation and reduced collagen synthesis induced by human periodontal ligament stem cells might underlie the negative effect of recombinant human bone morphogenetic protein-2 on periodontal regeneration
    • Song DS, Park JC, Jung IH et al. Enhanced adipogenic differentiation and reduced collagen synthesis induced by human periodontal ligament stem cells might underlie the negative effect of recombinant human bone morphogenetic protein-2 on periodontal regeneration. J Periodontal Res 2011;46:193-203.
    • (2011) J Periodontal Res , vol.46 , pp. 193-203
    • Song, D.S.1    Park, J.C.2    Jung, I.H.3
  • 14
    • 33748339795 scopus 로고    scopus 로고
    • Characterization of human bone cells derived from the maxillary alveolar ridge
    • Clausen C, Hermund NU, Donatsky O, Nielsen H. Characterization of human bone cells derived from the maxillary alveolar ridge. Clin Oral Implant Res 2006;17:533-540.
    • (2006) Clin Oral Implant Res , vol.17 , pp. 533-540
    • Clausen, C.1    Hermund, N.U.2    Donatsky, O.3    Nielsen, H.4
  • 16
    • 0037687418 scopus 로고    scopus 로고
    • SHED: stem cells from human exfoliated deciduous teeth
    • Miura M, Gronthos S, Zhao M et al. SHED: stem cells from human exfoliated deciduous teeth. Proc Nat Acad Sci USA 2003;100:5807-5812.
    • (2003) Proc Nat Acad Sci USA , vol.100 , pp. 5807-5812
    • Miura, M.1    Gronthos, S.2    Zhao, M.3
  • 17
    • 0036480623 scopus 로고    scopus 로고
    • The effects of an immediately pre-surgical chlorhexidine oral rinse on the bacterial contaminants of bone debris collected during dental implant surgery
    • Young MP, Korachi M, Carter DH, Worthington HV, McCord JF, Drucker DB. The effects of an immediately pre-surgical chlorhexidine oral rinse on the bacterial contaminants of bone debris collected during dental implant surgery. Clin Oral Implant Res 2002;13:20-29.
    • (2002) Clin Oral Implant Res , vol.13 , pp. 20-29
    • Young, M.P.1    Korachi, M.2    Carter, D.H.3    Worthington, H.V.4    McCord, J.F.5    Drucker, D.B.6
  • 18
    • 77953512596 scopus 로고    scopus 로고
    • Osteotomy irrigation: is it necessary?
    • Flanagan D. Osteotomy irrigation: is it necessary? Implant Dent 2010;19:241-249.
    • (2010) Implant Dent , vol.19 , pp. 241-249
    • Flanagan, D.1
  • 19
    • 80054933585 scopus 로고    scopus 로고
    • Induction of bone formation by Escherichia coli-expressed recombinant human bone morphogenetic protein-2 using block-type macroporous biphasic calcium phosphate in orthotopic and ectopic rat models
    • Park JC, So SS, Jung IH et al. Induction of bone formation by Escherichia coli-expressed recombinant human bone morphogenetic protein-2 using block-type macroporous biphasic calcium phosphate in orthotopic and ectopic rat models. J Periodontal Res 2011;46:682-690.
    • (2011) J Periodontal Res , vol.46 , pp. 682-690
    • Park, J.C.1    So, S.S.2    Jung, I.H.3
  • 20
    • 77249101466 scopus 로고    scopus 로고
    • Production and purification of recombinant human bone morphogenetic protein-2 in a E. coli expression system
    • Choi KH, Moon K, Kim SH, Cho KS, Yun JH, Jang KL. Production and purification of recombinant human bone morphogenetic protein-2 in a E. coli expression system. J Korean Acad Periodontol 2008;38:41-49.
    • (2008) J Korean Acad Periodontol , vol.38 , pp. 41-49
    • Choi, K.H.1    Moon, K.2    Kim, S.H.3    Cho, K.S.4    Yun, J.H.5    Jang, K.L.6
  • 21
    • 77249145300 scopus 로고    scopus 로고
    • The induction of bone formation in rat calvarial defects and subcutaneous tissues by recombinant human BMP-2, produced in Escherichia coli
    • Lee JH, Kim CS, Choi KH et al. The induction of bone formation in rat calvarial defects and subcutaneous tissues by recombinant human BMP-2, produced in Escherichia coli. Biomaterials 2010;31:3512-3519.
    • (2010) Biomaterials , vol.31 , pp. 3512-3519
    • Lee, J.H.1    Kim, C.S.2    Choi, K.H.3
  • 22
    • 79960341743 scopus 로고    scopus 로고
    • Isolation and characterization of human periodontal ligament (PDL) stem cells (PDLSCs) from the inflamed PDL tissue: in vitro and in vivo evaluations
    • Park JC, Kim JM, Jung IH et al. Isolation and characterization of human periodontal ligament (PDL) stem cells (PDLSCs) from the inflamed PDL tissue: in vitro and in vivo evaluations. J Clin Periodontol 2011;38:721-731.
    • (2011) J Clin Periodontol , vol.38 , pp. 721-731
    • Park, J.C.1    Kim, J.M.2    Jung, I.H.3
  • 23
    • 78651310848 scopus 로고    scopus 로고
    • Mechanism of alveolar bone loss in a collagen-induced arthritis model in mice
    • Park JC, Su C, Jung IH et al. Mechanism of alveolar bone loss in a collagen-induced arthritis model in mice. J Clin Periodontol 2011;38:122-130.
    • (2011) J Clin Periodontol , vol.38 , pp. 122-130
    • Park, J.C.1    Su, C.2    Jung, I.H.3
  • 24
    • 0032929399 scopus 로고    scopus 로고
    • Bone marrow and recombinant human bone morphogenetic protein-2 in osseous repair
    • Lane JM, Yasko AW, Tomin E et al. Bone marrow and recombinant human bone morphogenetic protein-2 in osseous repair. Clin Orthop Relat Res 1999;361:216-227.
    • (1999) Clin Orthop Relat Res , vol.361 , pp. 216-227
    • Lane, J.M.1    Yasko, A.W.2    Tomin, E.3
  • 25
    • 0001843334 scopus 로고    scopus 로고
    • Influence of osteogenic protein-1 (OP-1;BMP-7) and transforming growth factor-beta 1 on bone formation in vitro
    • Cheifetz S, Li IW, McCulloch CA, Sampath K, Sodek J. Influence of osteogenic protein-1 (OP-1;BMP-7) and transforming growth factor-beta 1 on bone formation in vitro. Connect Tissue Res 1996;35:71-78.
    • (1996) Connect Tissue Res , vol.35 , pp. 71-78
    • Cheifetz, S.1    Li, I.W.2    McCulloch, C.A.3    Sampath, K.4    Sodek, J.5
  • 26
    • 0031059353 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblasts
    • Chen D, Harris MA, Rossini G et al. Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblasts. Calcif Tissue Int 1997;60:283-290.
    • (1997) Calcif Tissue Int , vol.60 , pp. 283-290
    • Chen, D.1    Harris, M.A.2    Rossini, G.3
  • 27
    • 0025216220 scopus 로고
    • Recombinant human bone morphogenetic protein induces bone formation
    • Wang EA, Rosen V, D'Alessandro JS et al. Recombinant human bone morphogenetic protein induces bone formation. Proc Natl Acad Sci U S A 1990;87:2220-2224.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 2220-2224
    • Wang, E.A.1    Rosen, V.2    D'Alessandro, J.S.3
  • 28
    • 0030776315 scopus 로고    scopus 로고
    • Dependence of mesenchymal cell responses on duration of exposure to bone morphogenetic protein-2 in vitro
    • Puleo DA. Dependence of mesenchymal cell responses on duration of exposure to bone morphogenetic protein-2 in vitro. J Cell Physiol 1997;173:93-101.
    • (1997) J Cell Physiol , vol.173 , pp. 93-101
    • Puleo, D.A.1
  • 29
    • 0030307259 scopus 로고    scopus 로고
    • Expression of bone morphogenetic proteins by osteoinductive and non-osteoinductive human osteosarcoma cells
    • Raval P, Hsu HH, Schneider DJ et al. Expression of bone morphogenetic proteins by osteoinductive and non-osteoinductive human osteosarcoma cells. J Dent Res 1996;75:1518-1523.
    • (1996) J Dent Res , vol.75 , pp. 1518-1523
    • Raval, P.1    Hsu, H.H.2    Schneider, D.J.3
  • 30
    • 0345363018 scopus 로고    scopus 로고
    • Different effects of bone morphogenetic proteins 2, 4, 12, and 13 on the expression of cartilage and bone markers in the MC615 chondrocyte cell line
    • Valcourt U, Ronziere MC, Winkler P, Rosen V, Herbage D, Mallein-Gerin F. Different effects of bone morphogenetic proteins 2, 4, 12, and 13 on the expression of cartilage and bone markers in the MC615 chondrocyte cell line. Exp Cell Res 1999;251:264-274.
    • (1999) Exp Cell Res , vol.251 , pp. 264-274
    • Valcourt, U.1    Ronziere, M.C.2    Winkler, P.3    Rosen, V.4    Herbage, D.5    Mallein-Gerin, F.6
  • 31
    • 0029961204 scopus 로고    scopus 로고
    • The function of adipocytes in the bone marrow stroma: an update
    • Gimble JM, Robinson CE, Wu X, Kelly KA. The function of adipocytes in the bone marrow stroma: an update. Bone 1996;19:421-428.
    • (1996) Bone , vol.19 , pp. 421-428
    • Gimble, J.M.1    Robinson, C.E.2    Wu, X.3    Kelly, K.A.4
  • 32
    • 0034957648 scopus 로고    scopus 로고
    • Human BMP-7/OP-1 induces the growth and differentiation of adipocytes and osteoblasts in bone marrow stromal cell cultures
    • Chen TL, Shen WJ, Kraemer FB. Human BMP-7/OP-1 induces the growth and differentiation of adipocytes and osteoblasts in bone marrow stromal cell cultures. J Cell Biochem 2001;82:187-199.
    • (2001) J Cell Biochem , vol.82 , pp. 187-199
    • Chen, T.L.1    Shen, W.J.2    Kraemer, F.B.3
  • 33
    • 0029128268 scopus 로고
    • Bone morphogenetic proteins inhibit adipocyte differentiation by bone marrow stromal cells
    • Gimble JM, Morgan C, Kelly K et al. Bone morphogenetic proteins inhibit adipocyte differentiation by bone marrow stromal cells. J Cell Biochem 1995;58:393-402.
    • (1995) J Cell Biochem , vol.58 , pp. 393-402
    • Gimble, J.M.1    Morgan, C.2    Kelly, K.3
  • 34
    • 0036256989 scopus 로고    scopus 로고
    • Effects of cortisol and bone morphogenetic protein-2 on stromal cell differentiation: correlation with CCAAT-enhancer binding protein expression
    • Pereira RC, Delany AM, Canalis E. Effects of cortisol and bone morphogenetic protein-2 on stromal cell differentiation: correlation with CCAAT-enhancer binding protein expression. Bone 2002;30:685-691.
    • (2002) Bone , vol.30 , pp. 685-691
    • Pereira, R.C.1    Delany, A.M.2    Canalis, E.3
  • 35
    • 0042666802 scopus 로고    scopus 로고
    • Simvastatin induces osteoblastic differentiation and inhibits adipocytic differentiation in mouse bone marrow stromal cells
    • Song C, Guo Z, Ma Q et al. Simvastatin induces osteoblastic differentiation and inhibits adipocytic differentiation in mouse bone marrow stromal cells. Biochem Biophys Res Commun 2003;308:458-462.
    • (2003) Biochem Biophys Res Commun , vol.308 , pp. 458-462
    • Song, C.1    Guo, Z.2    Ma, Q.3
  • 36
    • 0345305861 scopus 로고    scopus 로고
    • Transcriptional characterization of bone morphogenetic proteins (BMPs)-mediated osteogenic signaling
    • Peng Y, Kang Q, Cheng H et al. Transcriptional characterization of bone morphogenetic proteins (BMPs)-mediated osteogenic signaling. J Cell Biochem 2003;90:1149-1165.
    • (2003) J Cell Biochem , vol.90 , pp. 1149-1165
    • Peng, Y.1    Kang, Q.2    Cheng, H.3
  • 37
    • 73349110430 scopus 로고    scopus 로고
    • Wnt and PPARgamma signaling in osteoblastogenesis and adipogenesis
    • Takada I, Kouzmenko AP, Kato S. Wnt and PPARgamma signaling in osteoblastogenesis and adipogenesis. Nat Rev Rheumatol 2009;5:442-447.
    • (2009) Nat Rev Rheumatol , vol.5 , pp. 442-447
    • Takada, I.1    Kouzmenko, A.P.2    Kato, S.3
  • 38
    • 47749111393 scopus 로고    scopus 로고
    • Molecular mechanism of switching adipocyte / osteoblast differentiation through regulation of PPAR-gamma function
    • Takada I, Kato S. Molecular mechanism of switching adipocyte / osteoblast differentiation through regulation of PPAR-gamma function. Clin calcium 2008;18:656-661.
    • (2008) Clin calcium , vol.18 , pp. 656-661
    • Takada, I.1    Kato, S.2
  • 39
    • 0036651815 scopus 로고    scopus 로고
    • Maintenance of osteoblastic and adipocytic differentiation potential with age and osteoporosis in human marrow stromal cell cultures
    • Justesen J, Stenderup K, Eriksen EF, Kassem M. Maintenance of osteoblastic and adipocytic differentiation potential with age and osteoporosis in human marrow stromal cell cultures. Calcif Tissue Int 2002;71:36-44.
    • (2002) Calcif Tissue Int , vol.71 , pp. 36-44
    • Justesen, J.1    Stenderup, K.2    Eriksen, E.F.3    Kassem, M.4


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