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Volumn 73, Issue 4-5, 2012, Pages 140-149

Protective Effect of FTY720 on Several Markers of Liver Injury Induced by Concanavalin A in Mice

Author keywords

Concanavalin A; FTY720; Liver injury; Nuclear factor B; Tumor necrosis factor

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CONCANAVALIN A; FINGOLIMOD; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84865550678     PISSN: 0011393X     EISSN: 18790313     Source Type: Journal    
DOI: 10.1016/j.curtheres.2012.07.001     Document Type: Article
Times cited : (6)

References (29)
  • 1
    • 79953139969 scopus 로고    scopus 로고
    • Treatment with the immunomodulator FTY720 does not promote spontaneous bacterial infections after experimental stroke in mice
    • Pfeilschifter W., Czech-Zechmeister B., Sujak M., et al. Treatment with the immunomodulator FTY720 does not promote spontaneous bacterial infections after experimental stroke in mice. Exp Transl Stroke Med 2011, 3:2-7.
    • (2011) Exp Transl Stroke Med , vol.3 , pp. 2-7
    • Pfeilschifter, W.1    Czech-Zechmeister, B.2    Sujak, M.3
  • 2
    • 35548984947 scopus 로고    scopus 로고
    • The immunomodulator FTY720 has a direct cytoprotective effect in oligodendrocyte progenitors
    • Coelho R.P., Payne S.G., Bittman R., et al. The immunomodulator FTY720 has a direct cytoprotective effect in oligodendrocyte progenitors. J Pharmacol Exp Ther 2007, 323:626-635.
    • (2007) J Pharmacol Exp Ther , vol.323 , pp. 626-635
    • Coelho, R.P.1    Payne, S.G.2    Bittman, R.3
  • 3
    • 84865552565 scopus 로고    scopus 로고
    • New developments in small molecule immunosuppressive drugs
    • Van der Boon R.M., Jardine J.D., Ottevanger B., et al. New developments in small molecule immunosuppressive drugs. Erasmus J Med 2011, 1:18-21.
    • (2011) Erasmus J Med , vol.1 , pp. 18-21
    • Van der Boon, R.M.1    Jardine, J.D.2    Ottevanger, B.3
  • 4
    • 0032720661 scopus 로고    scopus 로고
    • FTY720: Mechanisms of action and its effect on organ transplantation
    • Suzuki S. FTY720: Mechanisms of action and its effect on organ transplantation. Transplant Proc 1999, 31:2779-2782.
    • (1999) Transplant Proc , vol.31 , pp. 2779-2782
    • Suzuki, S.1
  • 5
    • 79959657080 scopus 로고    scopus 로고
    • Targeting lymphangiogenesis after islet transplantation prolongs islet allograft survival
    • Yin N., Zhang N., Xu J., et al. Targeting lymphangiogenesis after islet transplantation prolongs islet allograft survival. Transplantation 2011, 92:25-30.
    • (2011) Transplantation , vol.92 , pp. 25-30
    • Yin, N.1    Zhang, N.2    Xu, J.3
  • 6
    • 29644447371 scopus 로고    scopus 로고
    • Novel insights into the mechanism of action of FTY720 in a transgenic model of allograft rejection: implications for therapy of chronic rejection
    • Habicht A., Clarkson M.R., Yang J., et al. Novel insights into the mechanism of action of FTY720 in a transgenic model of allograft rejection: implications for therapy of chronic rejection. J Immunol 2006, 176:36-42.
    • (2006) J Immunol , vol.176 , pp. 36-42
    • Habicht, A.1    Clarkson, M.R.2    Yang, J.3
  • 7
    • 33645283403 scopus 로고    scopus 로고
    • FTY720, sphingosine 1-phosphate receptor modulator, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration
    • Kataoka H., Sugahara K., Shimano K., et al. FTY720, sphingosine 1-phosphate receptor modulator, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. Cell Mol Immunol 2005, 2:439-448.
    • (2005) Cell Mol Immunol , vol.2 , pp. 439-448
    • Kataoka, H.1    Sugahara, K.2    Shimano, K.3
  • 8
    • 33847644587 scopus 로고    scopus 로고
    • FTY720 induced Bcl-associated and Fas-independent apoptosis in human renal cancer cells in vitro and significantly reduced in vivo tumor growth in mouse xenograft
    • Ubai T., Azuma H., Kotake Y., et al. FTY720 induced Bcl-associated and Fas-independent apoptosis in human renal cancer cells in vitro and significantly reduced in vivo tumor growth in mouse xenograft. Anticancer Res 2007, 27:75-88.
    • (2007) Anticancer Res , vol.27 , pp. 75-88
    • Ubai, T.1    Azuma, H.2    Kotake, Y.3
  • 9
    • 33750589822 scopus 로고    scopus 로고
    • Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function
    • Idzko M., Hammad H., van Nimwegen M., et al. Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function. J Clin Invest 2006, 116:2935-2944.
    • (2006) J Clin Invest , vol.116 , pp. 2935-2944
    • Idzko, M.1    Hammad, H.2    van Nimwegen, M.3
  • 10
    • 79551674537 scopus 로고    scopus 로고
    • FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation
    • Choi J.W., Gardell S.E., Herr D.R., et al. FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation. Proc Natl Acad Sci U S A 2011, 108:751-756.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 751-756
    • Choi, J.W.1    Gardell, S.E.2    Herr, D.R.3
  • 11
    • 84862808216 scopus 로고    scopus 로고
    • Fingolimod (FTY720), the sphingosine 1-phosphate receptor modulator, as a new therapeutic drug in multiple sclerosis
    • Chiba K., Kataoka H., Seki N., et al. Fingolimod (FTY720), the sphingosine 1-phosphate receptor modulator, as a new therapeutic drug in multiple sclerosis. Inflammation and Regeneration 2011, 31:167-174.
    • (2011) Inflammation and Regeneration , vol.31 , pp. 167-174
    • Chiba, K.1    Kataoka, H.2    Seki, N.3
  • 12
    • 13244253993 scopus 로고    scopus 로고
    • Effect of 2-amino-2-(2-(4-octylphenyl) ethyl) propane-1,3-diol hydrochloride (FTY 720) on immune liver injury in mice
    • He J.H., Zhang H.N., Lin Z.B. Effect of 2-amino-2-(2-(4-octylphenyl) ethyl) propane-1,3-diol hydrochloride (FTY 720) on immune liver injury in mice. World J Gastroenterol 2005, 11:573-576.
    • (2005) World J Gastroenterol , vol.11 , pp. 573-576
    • He, J.H.1    Zhang, H.N.2    Lin, Z.B.3
  • 13
    • 35948977261 scopus 로고    scopus 로고
    • Concanavalin A protects mice from a lethal inoculation of intragastric Klebsiella pneumoniae and reduces the induced liver damage
    • Kuo C.F., Wang Y.H., Lei H.Y., et al. Concanavalin A protects mice from a lethal inoculation of intragastric Klebsiella pneumoniae and reduces the induced liver damage. Antimicrob Agents Chemother 2007, 51:3122-3130.
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 3122-3130
    • Kuo, C.F.1    Wang, Y.H.2    Lei, H.Y.3
  • 14
    • 79953875412 scopus 로고    scopus 로고
    • Kupffer cells contribute to concanavalin A-induced hepatic injury through a Th1 but not Th17 type response-dependent pathway in mice
    • Chen L., Xie X.J., Ye Y.F., et al. Kupffer cells contribute to concanavalin A-induced hepatic injury through a Th1 but not Th17 type response-dependent pathway in mice. Hepatobiliary Pancreat Dis Int 2011, 10:171-178.
    • (2011) Hepatobiliary Pancreat Dis Int , vol.10 , pp. 171-178
    • Chen, L.1    Xie, X.J.2    Ye, Y.F.3
  • 15
    • 84860000084 scopus 로고    scopus 로고
    • IL-17 in liver injury: an inflammatory issue?
    • Crispe I.N. IL-17 in liver injury: an inflammatory issue?. Immunol Cell Biol 2012, 90:369-370.
    • (2012) Immunol Cell Biol , vol.90 , pp. 369-370
    • Crispe, I.N.1
  • 16
    • 79955549815 scopus 로고    scopus 로고
    • CXCR3 deficiency exacerbates liver disease and abrogates tolerance in a mouse model of immune-mediated hepatitis
    • Erhardt A., Wegscheid C., Claass B., et al. CXCR3 deficiency exacerbates liver disease and abrogates tolerance in a mouse model of immune-mediated hepatitis. J Immunol 2011, 186:5284-5293.
    • (2011) J Immunol , vol.186 , pp. 5284-5293
    • Erhardt, A.1    Wegscheid, C.2    Claass, B.3
  • 17
    • 79959851182 scopus 로고    scopus 로고
    • Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis
    • Sitia G., Iannacone M., Aiolfi R., et al. Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis. PLoS Pathog 2011, 7:e1002061.
    • (2011) PLoS Pathog , vol.7
    • Sitia, G.1    Iannacone, M.2    Aiolfi, R.3
  • 18
    • 0034876657 scopus 로고    scopus 로고
    • Low-molecular-weight hyaluronic acid induces nuclear factor-κB-dependent resistance against tumor necrosis factor-α-mediated liver injury in mice
    • Wolf D., Schumann J., Koerber K., et al. Low-molecular-weight hyaluronic acid induces nuclear factor-κB-dependent resistance against tumor necrosis factor-α-mediated liver injury in mice. Hepatology 2001, 34:535.
    • (2001) Hepatology , vol.34 , pp. 535
    • Wolf, D.1    Schumann, J.2    Koerber, K.3
  • 19
    • 62449300643 scopus 로고    scopus 로고
    • Accumulation of fingolimod (FTY720) in lymphoid tissues contributes to prolonged efficacy
    • Sensken S.C., Bode C., Gräler M.H. Accumulation of fingolimod (FTY720) in lymphoid tissues contributes to prolonged efficacy. J Pharmacol Exp Ther 2009, 328:963-969.
    • (2009) J Pharmacol Exp Ther , vol.328 , pp. 963-969
    • Sensken, S.C.1    Bode, C.2    Gräler, M.H.3
  • 20
    • 63249093704 scopus 로고    scopus 로고
    • Genetic delineation of the pathways mediated by bid and JNK in tumor necrosis factor-alpha-induced liver injury in adult and embryonic mice
    • Ni H.M., Chen X., Shi Y.H., et al. Genetic delineation of the pathways mediated by bid and JNK in tumor necrosis factor-alpha-induced liver injury in adult and embryonic mice. J Biol Chem 2009, 284:4373-4382.
    • (2009) J Biol Chem , vol.284 , pp. 4373-4382
    • Ni, H.M.1    Chen, X.2    Shi, Y.H.3
  • 21
    • 80055043388 scopus 로고    scopus 로고
    • Hepatoprotective and antioxidant effects of licorice extract against CCl(4)-induced oxidative damage in rats
    • Huo H.Z., Wang B., Liang Y.K., et al. Hepatoprotective and antioxidant effects of licorice extract against CCl(4)-induced oxidative damage in rats. Int J Mol Sci 2011, 12:6529-6543.
    • (2011) Int J Mol Sci , vol.12 , pp. 6529-6543
    • Huo, H.Z.1    Wang, B.2    Liang, Y.K.3
  • 22
    • 80555134787 scopus 로고    scopus 로고
    • Activation of MDL-1 (CLEC5A) on immature myeloid cells triggers lethal shock in mice
    • Cheung R., Shen F., Phillips J.H., et al. Activation of MDL-1 (CLEC5A) on immature myeloid cells triggers lethal shock in mice. J Clin Invest 2011, 121:4446-4461.
    • (2011) J Clin Invest , vol.121 , pp. 4446-4461
    • Cheung, R.1    Shen, F.2    Phillips, J.H.3
  • 23
    • 62849092266 scopus 로고    scopus 로고
    • NF-kappaB in liver diseases: a target for drug therapy
    • Muriel P. NF-kappaB in liver diseases: a target for drug therapy. J Appl Toxicol 2009, 29:91-100.
    • (2009) J Appl Toxicol , vol.29 , pp. 91-100
    • Muriel, P.1
  • 24
    • 34147197520 scopus 로고    scopus 로고
    • Gemtuzumab ozogamicin-associated sinusoidal obstructive syndrome (SOS): an overview from the research on adverse drug events and reports (RADAR) project
    • McKoy J.M., Angelotta C., Bennett C.L., et al. Gemtuzumab ozogamicin-associated sinusoidal obstructive syndrome (SOS): an overview from the research on adverse drug events and reports (RADAR) project. Leuk Res 2007, 31:599-604.
    • (2007) Leuk Res , vol.31 , pp. 599-604
    • McKoy, J.M.1    Angelotta, C.2    Bennett, C.L.3
  • 25
    • 33745064418 scopus 로고    scopus 로고
    • Safety analyses of adalimumab (HUMIRA) in global clinical trials and US postmarketing surveillance of patients with rheumatoid arthritis
    • Schiff M.H., Burmester G.R., Kent J.D., et al. Safety analyses of adalimumab (HUMIRA) in global clinical trials and US postmarketing surveillance of patients with rheumatoid arthritis. Ann Rheum Dis 2006, 65:889-894.
    • (2006) Ann Rheum Dis , vol.65 , pp. 889-894
    • Schiff, M.H.1    Burmester, G.R.2    Kent, J.D.3
  • 26
    • 0141532294 scopus 로고    scopus 로고
    • Decreased hepatic nitric oxide production contributes to the development of rat sinusoidal obstruction syndrome
    • DeLeve L.D., Wang X., Kanel G.C., et al. Decreased hepatic nitric oxide production contributes to the development of rat sinusoidal obstruction syndrome. Hepatology 2003, 38:900-908.
    • (2003) Hepatology , vol.38 , pp. 900-908
    • DeLeve, L.D.1    Wang, X.2    Kanel, G.C.3
  • 27
    • 77953587983 scopus 로고    scopus 로고
    • Oxidative stress signaling underlying liver disease and hepatoprotective mechanisms
    • Videla L.A. Oxidative stress signaling underlying liver disease and hepatoprotective mechanisms. World J Hepatol 2009, 1:72-78.
    • (2009) World J Hepatol , vol.1 , pp. 72-78
    • Videla, L.A.1
  • 28
    • 70349308534 scopus 로고    scopus 로고
    • Mechanisms of liver disease: cross-talk between the NF-kappaB and JNK pathways
    • Papa S., Bubici C., Zazzeroni F., et al. Mechanisms of liver disease: cross-talk between the NF-kappaB and JNK pathways. Biol Chem 2009, 390:965-976.
    • (2009) Biol Chem , vol.390 , pp. 965-976
    • Papa, S.1    Bubici, C.2    Zazzeroni, F.3
  • 29
    • 79951781882 scopus 로고    scopus 로고
    • Role of glucocorticoid receptor and nuclear factor kappa B in rat hepatic injury after traumatic hemorrhagic shock
    • Luo D., Huang X., Liu B., et al. Role of glucocorticoid receptor and nuclear factor kappa B in rat hepatic injury after traumatic hemorrhagic shock. Afr J Pharm Pharmacol 2010, 4:865-873.
    • (2010) Afr J Pharm Pharmacol , vol.4 , pp. 865-873
    • Luo, D.1    Huang, X.2    Liu, B.3


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