메뉴 건너뛰기




Volumn 34, Issue 5, 2012, Pages 517-524

Frequency of VKORC1 (C1173T) and CYP2C9 genetic polymorphisms in Egyptians and their influence on warfarin maintenance dose: Proposal for a new dosing regimen

Author keywords

CYP2C9; Real time PCR; VKORC1; Warfarin

Indexed keywords

CYTOCHROME P450 2C9; WARFARIN;

EID: 84865549975     PISSN: 17515521     EISSN: 1751553X     Source Type: Journal    
DOI: 10.1111/j.1751-553X.2012.01426.x     Document Type: Article
Times cited : (23)

References (31)
  • 1
    • 0037565623 scopus 로고    scopus 로고
    • Pharmacokinetics of oral anticoagulants
    • Daly A, King B. Pharmacokinetics of oral anticoagulants. Pharmacogenetics 2003;13:247-52.
    • (2003) Pharmacogenetics , vol.13 , pp. 247-252
    • Daly, A.1    King, B.2
  • 2
    • 34248347478 scopus 로고    scopus 로고
    • The Pharmacogenetics of CYP2C9 and CYP2C19: ethnic variation and clinical significance
    • Rosemary J, Adithan C. The Pharmacogenetics of CYP2C9 and CYP2C19: ethnic variation and clinical significance. Curr Clin Pharmacol 2007;2:93-109.
    • (2007) Curr Clin Pharmacol , vol.2 , pp. 93-109
    • Rosemary, J.1    Adithan, C.2
  • 3
    • 39449109003 scopus 로고    scopus 로고
    • A rapid-ACCE review of CYP2C9 and VKORC1 alleles testing to inform warfarin dosing in adults at elevated risk for thrombotic events to avoid serious bleeding
    • McClain MR, Palomaki GE, Piper M, Haddow JE. A rapid-ACCE review of CYP2C9 and VKORC1 alleles testing to inform warfarin dosing in adults at elevated risk for thrombotic events to avoid serious bleeding. Genet Med 2008;10:89-98.
    • (2008) Genet Med , vol.10 , pp. 89-98
    • McClain, M.R.1    Palomaki, G.E.2    Piper, M.3    Haddow, J.E.4
  • 5
    • 11244332058 scopus 로고    scopus 로고
    • A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose anticoagulant effect of warfarin
    • D'Andrea G, D'Ambrosio R, Di Perna P, Chetta M, Santacroce R, Brancaccio V, Grandone E, Margaglione M. A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose anticoagulant effect of warfarin. Blood 2005;105:645-9.
    • (2005) Blood , vol.105 , pp. 645-649
    • D'Andrea, G.1    D'Ambrosio, R.2    Di Perna, P.3    Chetta, M.4    Santacroce, R.5    Brancaccio, V.6    Grandone, E.7    Margaglione, M.8
  • 7
    • 84877254416 scopus 로고    scopus 로고
    • New issues in oral anticoagulants
    • Francis C. New issues in oral anticoagulants. Am Soc Hematol 2008;25:260-4.
    • (2008) Am Soc Hematol , vol.25 , pp. 260-264
    • Francis, C.1
  • 8
    • 34247141066 scopus 로고    scopus 로고
    • Warfarin dose and the pharmacogenomics next term of CYP2C9 and VKORC1-rationale and perspectives
    • Yin T, Miyata T. Warfarin dose and the pharmacogenomics next term of CYP2C9 and VKORC1-rationale and perspectives. Thromb Res 2007;120:1-10.
    • (2007) Thromb Res , vol.120 , pp. 1-10
    • Yin, T.1    Miyata, T.2
  • 10
    • 67349185332 scopus 로고    scopus 로고
    • A systematic review of pharmacogenetic dosing of warfarin. Genetic testing before anticoagulation?
    • Kangelaris K, Bent S, Nussbaum R, Garcia D, Tice J. A systematic review of pharmacogenetic dosing of warfarin. Genetic testing before anticoagulation?. J Gen Intern Med 2009;24:656-64.
    • (2009) J Gen Intern Med , vol.24 , pp. 656-664
    • Kangelaris, K.1    Bent, S.2    Nussbaum, R.3    Garcia, D.4    Tice, J.5
  • 11
    • 58149234043 scopus 로고    scopus 로고
    • SYBR Green-based real time PCR assay for detection of VKORC1 and CYP2C9 polymorphisms that modulate warfarin dose requirement
    • Huang S, Li Q, Zu S, Li L, Xiong F, Jia Y, Xu X. SYBR Green-based real time PCR assay for detection of VKORC1 and CYP2C9 polymorphisms that modulate warfarin dose requirement. Clin Chem Lab Med 2009;47:26-31.
    • (2009) Clin Chem Lab Med , vol.47 , pp. 26-31
    • Huang, S.1    Li, Q.2    Zu, S.3    Li, L.4    Xiong, F.5    Jia, Y.6    Xu, X.7
  • 13
    • 0033950347 scopus 로고    scopus 로고
    • Rheumatic fever - is it still a problem
    • Olivier C. Rheumatic fever - is it still a problem. J Antimicrob Chemother 2000;45:13-21.
    • (2000) J Antimicrob Chemother , vol.45 , pp. 13-21
    • Olivier, C.1
  • 15
    • 38349126516 scopus 로고    scopus 로고
    • Influence of CYP2C9 and VKORC1 1173C/T genotype on the risk of hemorrhagic complications in African-American and European-American patients on Warfarin
    • Limdi N, Mc Gwin G, Goldstein JA, Beasley TM, Arnett DK, Adler BK, Baird MF, Acton RT. Influence of CYP2C9 and VKORC1 1173C/T genotype on the risk of hemorrhagic complications in African-American and European-American patients on Warfarin. Clin Pharmacol Ther 2008;83:312-21.
    • (2008) Clin Pharmacol Ther , vol.83 , pp. 312-321
    • Limdi, N.1    Mc Gwin, G.2    Goldstein, J.A.3    Beasley, T.M.4    Arnett, D.K.5    Adler, B.K.6    Baird, M.F.7    Acton, R.T.8
  • 16
    • 78650840777 scopus 로고    scopus 로고
    • Contribution of 1173C>T polymorphism in the VKORC1 gene to warfarin dose requirements in Han Chinese patients receiving anticoagulation
    • Yang J, Huang C, Shen Z, Miao L. Contribution of 1173C>T polymorphism in the VKORC1 gene to warfarin dose requirements in Han Chinese patients receiving anticoagulation. Int J Clin Pharmacol Ther 2011;49:23-9.
    • (2011) Int J Clin Pharmacol Ther , vol.49 , pp. 23-29
    • Yang, J.1    Huang, C.2    Shen, Z.3    Miao, L.4
  • 17
    • 0035987174 scopus 로고    scopus 로고
    • Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian population
    • Hamdy S, Hiratsuka M, Narahara K, El-Enany M, Moursi N, Ahmed M, Mizugaki M. Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian population. Br J Clin Pharmacol 2002;53:596-603.
    • (2002) Br J Clin Pharmacol , vol.53 , pp. 596-603
    • Hamdy, S.1    Hiratsuka, M.2    Narahara, K.3    El-Enany, M.4    Moursi, N.5    Ahmed, M.6    Mizugaki, M.7
  • 18
    • 33845765706 scopus 로고    scopus 로고
    • Frequency of CYP2C9 genotypes among Omani patients receiving warfarin and its correlation with warfarin dose
    • Tanira M, Al-Mukhaini M, Al-Hinai A, Al Balushi K, Ahmed I. Frequency of CYP2C9 genotypes among Omani patients receiving warfarin and its correlation with warfarin dose. Commun Genet 2007;10:32-7.
    • (2007) Commun Genet , vol.10 , pp. 32-37
    • Tanira, M.1    Al-Mukhaini, M.2    Al-Hinai, A.3    Al Balushi, K.4    Ahmed, I.5
  • 20
    • 0034283762 scopus 로고    scopus 로고
    • Influence of cytochrome P-450 CYP2C9 polymorphisms on warfarin sensitivity and risk of over-anticoagulation in patients on long-term treatment
    • Taube J, Halsall D, Baglin T. Influence of cytochrome P-450 CYP2C9 polymorphisms on warfarin sensitivity and risk of over-anticoagulation in patients on long-term treatment. Blood 2000;96:1816-9.
    • (2000) Blood , vol.96 , pp. 1816-1819
    • Taube, J.1    Halsall, D.2    Baglin, T.3
  • 22
    • 33645474219 scopus 로고    scopus 로고
    • Malaysian Indians are genetically similar to Caucasians: CYP2C9 polymorphism
    • Zainuddin Z, Teh L, Suhaimi A, Ismail R. Malaysian Indians are genetically similar to Caucasians: CYP2C9 polymorphism. J Clin Pharmacol Ther 2006;31:187-91.
    • (2006) J Clin Pharmacol Ther , vol.31 , pp. 187-191
    • Zainuddin, Z.1    Teh, L.2    Suhaimi, A.3    Ismail, R.4
  • 23
    • 0036263813 scopus 로고    scopus 로고
    • Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data
    • Lee C, Goldstein J, Pieper J. Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data. Pharmacogenetics 2002;12:251-63.
    • (2002) Pharmacogenetics , vol.12 , pp. 251-263
    • Lee, C.1    Goldstein, J.2    Pieper, J.3
  • 24
    • 41249091755 scopus 로고    scopus 로고
    • Oral anticoagulants: pharmacogenetics relationship between genetic and nongenetic factors
    • D'Andrea G, D'Ambrosio R, Margaglione M. Oral anticoagulants: pharmacogenetics relationship between genetic and nongenetic factors. Blood Rev 2008;22:127-40.
    • (2008) Blood Rev , vol.22 , pp. 127-140
    • D'Andrea, G.1    D'Ambrosio, R.2    Margaglione, M.3
  • 26
    • 49549107264 scopus 로고    scopus 로고
    • Pharmacogenetics of oral anticoagulants: a basis for dose individualization
    • Stehle S, Kirchheiner J, Lazar A, Fuhr U. Pharmacogenetics of oral anticoagulants: a basis for dose individualization. Clin Pharmacokinet 2008;47:565-94.
    • (2008) Clin Pharmacokinet , vol.47 , pp. 565-594
    • Stehle, S.1    Kirchheiner, J.2    Lazar, A.3    Fuhr, U.4
  • 29
    • 72049115752 scopus 로고    scopus 로고
    • Interethnic differences of CYP2C9 alleles in healthy Hungarian and Roma population samples: relationship to worldwide allelic frequencies
    • Sipeky C, Lakner L, Szabo M, Takacs I, Tamasi V, Polgar N, Falus A, Melegh B. Interethnic differences of CYP2C9 alleles in healthy Hungarian and Roma population samples: relationship to worldwide allelic frequencies. Blood Cell Mol Dis 2009;43:239-42.
    • (2009) Blood Cell Mol Dis , vol.43 , pp. 239-242
    • Sipeky, C.1    Lakner, L.2    Szabo, M.3    Takacs, I.4    Tamasi, V.5    Polgar, N.6    Falus, A.7    Melegh, B.8
  • 31
    • 77954648173 scopus 로고    scopus 로고
    • The impact of genetic polymorphisms and patient characteristics on warfarin dose requirements: a cross-sectional study in Iran
    • Namazi S, Azarpira N, Hendijani F, Khorshid MB, Vessal G, Mehdipour AR. The impact of genetic polymorphisms and patient characteristics on warfarin dose requirements: a cross-sectional study in Iran. Clin Ther 2010;32:1050-60.
    • (2010) Clin Ther , vol.32 , pp. 1050-1060
    • Namazi, S.1    Azarpira, N.2    Hendijani, F.3    Khorshid, M.B.4    Vessal, G.5    Mehdipour, A.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.