An investigation of the co-variation in circulating levels of a large number of environmental contaminants

Journal of Exposure Science and Environmental Epidemiology

Volumn 22, Issue 5, 2012, Pages 476-482

  Lampa, Erik ^a   Lind, Lars ^b   Hermansson, Anna Bornefalk ^a   Salihovic, Samira ^c   Van Bavel, Bert ^c   Lind, P Monica ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^c ÖREBRO UNIVERSITY   (Sweden)

Author keywords

environmental contaminants; mixtures; multivariate analysis

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; BIOLOGICAL MARKER; CHLORINE DERIVATIVE; PESTICIDE; PHENOL DERIVATIVE; PHTHALIC ACID DERIVATIVE; POLYCHLORINATED BIPHENYL;

ADOLESCENT; ADULT; AGE; AGED; ARTICLE; BLOOD; CHILD; CLUSTER ANALYSIS; ENVIRONMENTAL EXPOSURE; FEMALE; HUMAN; MALE; MIDDLE AGED; NUTRITION; POLLUTANT; PRINCIPAL COMPONENT ANALYSIS; SEX DIFFERENCE; STATISTICS; SWEDEN; UNITED STATES;

ADOLESCENT; ADULT; AGE FACTORS; AGED; BIOLOGICAL MARKERS; CHILD; CHLORINE COMPOUNDS; CLUSTER ANALYSIS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; FEMALE; HUMANS; MALE; MIDDLE AGED; NUTRITION SURVEYS; PESTICIDES; PHENOLS; PHTHALIC ACIDS; POLYCHLORINATED BIPHENYLS; PRINCIPAL COMPONENT ANALYSIS; SEX FACTORS; SWEDEN; UNITED STATES; YOUNG ADULT;

EID: 84865525314     PISSN: 15590631     EISSN: 1559064X     Source Type: Journal    
DOI: 10.1038/jes.2012.41     Document Type: Article

References (25)

1. European Chemicals Agency. ECHA Website. 2011.
2. Kortenkamp A., Backhaus T., and Faust M., State of the Art Report on Mixture Toxicology - Final Report. 2009.
3. Silva E., Rajapakse N., Scholze M., Backhaus T., Ermler S., and Kortenkamp A. Joint effects of heterogeneous estrogenic chemicals in the E-Screen - exploring the applicability of concentration addition. Toxicol Sci 2011: 122: 383-394.
4. McFarland V.A., and Clarke J.U. Environmental occurrence, abundance, and potential toxicity of polychlorinated biphenyl congeners: Considerations for a congener-specific analysis. Environ Health Perspect 1989: 81: 225-239.
5. Moysich K.B., Mendola P., Schisterman E.F., Freudenheim J.L., Ambrosone C.B., and Vena J.E., et al. An evaluation of proposed frameworks for grouping polychlorinated biphenyl (PCB) congener data into meaningful analytic units. Am J Ind Med 1999: 35: 223-231.
6. Wolff M.S., Camann D., Gammon M., and Stellman S.D. Proposed PCB congener groupings for epidemiological studies. Environ Health Perspect 1997: 105: 13-14.
7. Lind L., Fors N., Hall J., Marttala K., and Stenborg A. A comparison of three different methods to evaluate endothelium-dependent vasodilation in the elderly: The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study. Arterioscler Thromb Vasc Biol 2005: 25: 2368-2375.
8. Salihovic S., Mattioli L., Lindstrom G., Lind L., Lind P.M., and Bavel B.V. A rapid method for screening of the Stockholm convention POPs in small amounts of human plasma using SPE and HRGC/HRMS. Chemosphere 2012: 86: 747-753.
9. Olsen L., Lind P.M., and Lind L. Gender differences for associations between circulating levels of metals and coronary risk in the elderly. Int J Hyg Environ Health 2012: 215: 411-417.
10. Olsen L., Lampa E., Birkholz D.A., Lind L., and Lind P.M. Circulating levels of bisphenol A (BPA) and phthalates in an elderly population in Sweden, based on the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS). Ecotoxicol Environ Saf 2011: 75: 242-248.
11. Centers for Disease Control and Prevention (CDC). National Health and Nutrition Examination Survey Data, Vol. 2011. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Hyattsville, MD, 2003-2004.
12. Rodushkin I., and Axelsson M.D. Application of double focusing sector field ICPMS for multielemental characterization of human hair and nails. Part I. Analytical methodology. Sci Total Environ 2000: 250: 83-100.
13. Calafat A.M., Kuklenyik Z., Reidy J.A., Caudill S.P., Ekong J., and Needham L.L. Urinary concentrations of bisphenol A and 4-nonylphenol in a human reference population. Environ Health Perspect 2005: 113: 391-395.
14. Silva M.J., Malek N.A., Hodge C.C., Reidy J.A., Kato K., and Barr D.B., et al. Improved quantitative detection of 11 urinary phthalate metabolites in humans using liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2003: 789: 393-404.
15. Hollander M., and Wolfe D.A. Nonparametric Statistical Methods, 2nd edn John Wiley & Sons, New York, 1999.
16. Shimodaira H. An approximately unbiased test of phylogenetic tree selection. Syst Biol 2002: 51: 492-508.
17. Suzuki R., and Shimodaira H. Pvclust: An R package for assessing the uncertainty in hierarchical clustering. Bioinformatics 2006: 22: 1540-1542.
18. Harrell F.E. Regression Modeling Strategies: With Applications to Linear Models, Logistic Regression, and Survival Analysis, 2nd edn Springer Science+Business Media, Inc., New York, NY, 2001.
19. R Development Core Team. R: A Language and Environment for Statistical Computing. 2.10.0 ed. R Foundation for Statistical Computing, Vienna, Austria 2009.
20. Harrell F.E. Hmisc: Harrell miscellaneous. R package version 3.8-3. 3.8-3 edn., 2010.
21. Glynn A.W., Wolk A., Aune M., Atuma S., Zettermark S., and Maehle-Schmid M., et al. Serum concentrations of organochlorines in men: A search for markers of exposure. Sci Total Environ 2000: 263: 197-208.
22. Glynn A.W., Granath F., Aune M., Atuma S., Darnerud P.O., and Bjerselius R., et al. Organochlorines in Swedish women: Determinants of serum concentrations. Environ Health Perspect 2003: 111: 349-355.
23. Stroheker T., Cabaton N., Nourdin G., Regnier J.F., Lhuguenot J.C., and Chagnon M.C. Evaluation of anti-androgenic activity of di-(2-ethylhexyl) phthalate. Toxicology 2005: 208: 115-121.
24. Bushnik T., Haines D., Levallois P., Levesque J., Van Oostdam J., and Viau C. Lead and bisphenol A concentrations in the Canadian population. Health Rep 2010: 21: 7-18.
25. Wolff M.S., Anderson H.A., Britton J.A., and Rothman N. Pharmakokinetic variability and modern epidemiology-the example of dichlorodiphenyltrichoroethane, body mass index, and birth cohort. Cancer Epidemiol Biomarkers Prev 2007: 16: 1925-1930.