Association between sequence variations of the Mediterranean fever gene and fibromyalgia syndrome in a cohort of Turkish patients

Clinica Chimica Acta

Volumn 414, Issue , 2012, Pages 36-40

  Karakus, Nevin ^a,b   Yigit, Serbulent ^b   Inanir, Ahmet ^b   Inanir, Sema ^b   Toprak, Huriye ^b   Okan, Sevil ^b  

^a ONDOKUZ MAYIS UNIVERSITY   (Turkey)

^b GAZIOSMANPASA UNIVERSITY   (Turkey)

Author keywords

Fibromyalgia; MEFV gene mutation; R202Q

Indexed keywords

ADENINE; ALANINE; ARGININE; GENOMIC DNA; GLUTAMIC ACID; GLUTAMINE; GUANINE; ISOLEUCINE; METHIONINE; PROLINE; SERINE; VALINE;

ADULT; ARTICLE; CASE CONTROL STUDY; COHORT ANALYSIS; CONCENTRATION LOSS; CONTROLLED STUDY; DISEASE SEVERITY; DNA ISOLATION; DRY EYE; DYSMENORRHEA; DYSURIA; FAMILIAL MEDITERRANEAN FEVER; FATIGUE; FEMALE; FIBROMYALGIA; FIBROMYALGIA SYNDROME; GENE; GENE FREQUENCY; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETIC VARIATION; GENOTYPE; HEADACHE; HETEROZYGOTE; HOMOZYGOSITY; HUMAN; IRRITABLE COLON; MAJOR CLINICAL STUDY; MALE; MEFV GENE; MISSENSE MUTATION; MORNING FATIGUE; MUTATIONAL ANALYSIS; PARESTHESIA; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAYNAUD PHENOMENON; RESTLESS LEGS SYNDROME; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEQUENCE ANALYSIS; SLEEP DISORDER; TURK (PEOPLE); XEROSTOMIA; GENETIC VARIABILITY; GENETICS; MIDDLE AGED; SYNDROME; TURKEY (REPUBLIC);

ADULT; CASE-CONTROL STUDIES; COHORT STUDIES; FAMILIAL MEDITERRANEAN FEVER; FEMALE; FIBROMYALGIA; GENETIC VARIATION; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MUTATION, MISSENSE; POLYMORPHISM, GENETIC; SYNDROME; TURKEY;

EID: 84865522627     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2012.07.019     Document Type: Article

References (31)

1. Wolfe, F., Smythe, H.A., Yunus, M.B., et al. The American college of rheumatology 1990 criteria for the classification of fibromyalgia. Report of the multicenter criteria committee. Arthritis Rheum 33:1990 (1990), 160–172.
2. Neumann, L., Buskila, D., Epidemiology of fibromyalgia. Curr. Pain Headache Rep. 7 (2003), 362–368.
3. Wolfe, F., Ross, K., Anderson, J., Russell, I.J., Hebert, L., The prevalence and characteristics of fibromyalgia in the general population. Arthritis Rheum. 38 (1995), 19–28.
4. Topbas, M., Cakırbay, H., Gulec, H., Akgol, E., Ak, I., Can, G., The prevalence of fibromyalgia in women aged 20–64 in Turkey. Scand J Rheumatol 34 (2005), 140–144.
5. Diatchenko, L., Nackley, A., Slade, G., Fillingim, R., Maixner, W., Idiopathic pain disorders: pathways of vulnerability. Pain 123 (2006), 226–230.
6. Buskila, D., Sarzi-Puttini, P., Biology and therapy of fibromyalgia. Genetic aspects of fibromyalgia syndrome. Arthritis Res. Ther., 8, 2006, 218.
7. Ablin, J.N., Cohen, H., Buskila, D., Mechanisms of disease: genetics of fibromyalgia. Nat Clin Pract Rheumatol 2 (2006), 671–678.
8. Lee, Y.H., Choi, S.J., Ji, J.D., Song, G.G., Candidate gene studies of fibromyalgia: a systematic review and meta-analysis. Rheumatol Int 32 (2012), 417–426.
9. Samuels, J., Ozen, S., Familial Mediterranean fever and the other autoinflammatory syndromes: evaluation of the patient with recurrent fever. Curr Opin Rheumatol 18 (2006), 108–117.
10. Onen, F., Familial Mediterranean fever. Rheumatol Int 26 (2006), 489–496.
11. Gursoy, S., Erdal, E., Herken, H., Madenci, E., Alasehirli, B., Association of T102C polymorphism of the 5HT2A receptor gene with pyschiatric status in fibromyalgia syndrome. Rheumatol Int 21 (2001), 58–61.
12. Gursoy, S., Absence of association of the serotonin transporter gene polymorphism with mentally healthy subset of fibromyalgia patients. Clin Rheumatol 21 (2002), 194–197.
13. Gursoy, S., Erdal, E., Herken, H., Madenci, E., Alasehirli, B., Erdal, N., Significance of catechol-O-methyltransferase gene polymorphism in fibromyalgia syndrome. Rheumatol Int 23 (2003), 104–107.
14. Alasehirli, B., Demiryürek, S., Arica, E., Gürsoy, S., Demiryürek, A.T., No evidence for an association between the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and fibromyalgia syndrome. Rheumatol Int 27 (2007), 275–280.
15. Gursoy, S., Erdal, E., Sezgin, M., et al. Which genotype of MAO gene that the patients have are likely to be most susceptible to the symptoms of fibromyalgia?. Rheumatol Int 28 (2008), 307–311.
16. Tander, B., Gunes, S., Boke, O., et al. Polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase genes: a study on fibromyalgia susceptibility. Rheumatol Int 28 (2008), 685–691.
17. Feng, J., Zhang, Z., Li, W., et al. Missense mutations in the MEFV gene are associated with fibromyalgia syndrome and correlate with elevated IL-1beta plasma levels. PLoS One, 30, 2009, 8480.
18. Booth, D.R., Gillmore, J.D., Lachmann, H.J., et al. The genetic basis of autosomal dominant familial Mediterranean fever. QJM 93 (2000), 217–221.
19. Shinar, Y., Livneh, A., Villa, Y., et al. Common mutations in the Mediterranean fever gene associated with rapid progression to disability in non-Ashkenazi Jewish multiple sclerosis patients. Genes Immunol 4 (2003), 197–203.
20. Rabinovich, E., Livneh, A., Langevitz, P., et al. Severe disease in patients with rheumatoid arthritis carrying a mutation in the Mediterranean fever gene. Ann Rheum Dis 64 (2005), 1009–1014.
21. Giaglis, S., Mimidis, K., Papadopoulos, V., et al. Increased frequency of mutations in the gene responsible for familial Mediterranean fever (MEFV) in a cohort of patients with ulcerative colitis: evidence for a potential disease-modifying effect. Dig Dis Sci 51 (2006), 687–692.
22. Rabinovich, E., Shinar, Y., Leiba, M., Ehrenfeld, M., Langevitz, P., Livneh, A., Common FMF alleles may predispose to development of Behcet's disease with increased risk for venous thrombosis. Scand J Rheumatol 36 (2007), 48–52.
23. Canete, J.D., Arostegui, J.I., Queiro, R., et al. An unexpectedly high frequency of MEFV mutations in patients with anti‐citrullinated protein antibody‐negative palindromic rheumatism. Arthritis Rheum 56 (2007), 2784–2788.
24. Pras, E., Aksentijevich, I., Gruberg, L., et al. Mapping of a gene causing familial Mediterranean fever to the short arm of chromosome 16. N Engl J Med 326 (1992), 1509–1513.
25. Ting, J.P., Kastner, D.L., Hoffman, H.M., CATERPILLERs, pyrin and hereditary immunological disorders. Nat Rev Immunol 6 (2006), 183–195.
26. Papin, S., Cuenin, S., Agostini, L., et al. The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing. Cell Death Differ 14 (2007), 1457–1466.
27. Yepiskoposyan, L., Harutyunyan, A., Population genetics of familial Mediterranean fever: a review. Eur J Hum Genet 15 (2007), 911–916.
28. Aldea, A., Calafell, F., ArósteguiI, J.I., et al. The west side story: MEFV haplotype in Spanish FMF patients and controls, and evidence of high LD and a recombination “hot-spot” at the MEFV locus. Hum Mutat, 23, 2004, 399.
29. Gershoni-Baruch, R., Kepten, I., Shinawi, M., Brik, R., Direct detection of common mutations in the familial Mediterranean fever gene (MEFV) using naturally occurring and primer mediated restriction fragment analysis. Hum Mutat 14 (1998), 91–94.
30. Aksentijevich, I., Torosyan, Y., Samuels, J., et al. Mutation and haplotype studies of familial Mediterranean fever reveal new ancestral relationships and evidence for a high carrier frequency with reduced penetrance in the Ashkenazi Jewish population. Am J Hum Genet 64 (1999), 949–962.
31. Ozturk, A., Ozcakar, B., Ekim, M., Akar, N., Is MEFV gene Arg202Gln (605 G>A) a disease-causing mutation?. Turk J Med Sci 38 (2008), 205–208.